Note that this term represents a protein complex, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'.
GO:0000123
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histone acetyltransferase complex
Cellular Component
Definition (GO:0000123 GONUTS page)
A protein complex that possesses histone acetyltransferase activity.
Comments
Note that this term represents a protein complex, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
histone acetylase complex | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000123
Child Term | Relationship to GO:0000123 |
---|---|
H3 histone acetyltransferase complex
|
is_a |
H4 histone acetyltransferase complex
|
is_a |
SAGA-type complex
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0000123 | histone acetyltransferase complex | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y7L4 | 10116 | A0A8I5Y7L4_RAT | GO:0005694 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q14TE9 | 10116 | Q14TE9_RAT | GO:0005694 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q63177 | 10116 | Q63177_RAT | GO:0005694 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q64511 | 10090 | TOP2B_MOUSE | GO:0005694 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:11835579 | |
NOT-qualified manual | protein | Q8NFT6 | 9606 | DBF4B_HUMAN | GO:0000785 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15668232 | |
NOT-qualified manual | protein | Q9URY0 | 284812 | YTM1_SCHPO | GO:0000785 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:36423630 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR014744 | Nuclear receptor coactivator, CREB-bp-like, interlocking |
InterPro | IPR015418 | Chromatin modification-related protein Eaf6 |
InterPro | IPR026180 | KAT8 regulatory NSL complex subunit 1 |
InterPro | IPR026316 | KAT8 regulatory NSL complex subunit 2 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000123 based on ALL annotations
The top 100 of 1,010 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone acetyltransferase complex
|
5,662.38 | 100.00 | 34,427 | 34,427 |
histone acetyltransferase activity
|
1,496.45 | 19.77 | 15,144 | 57,303 |
histone H4K8 acetyltransferase activity
|
1,760.25 | 14.56 | 7,403 | 23,814 |
histone H4K5 acetyltransferase activity
|
1,760.25 | 14.56 | 7,403 | 23,814 |
histone H4K12 acetyltransferase activity
|
1,757.99 | 14.56 | 7,409 | 23,864 |
histone H3K14 acetyltransferase activity
|
1,738.45 | 14.31 | 7,280 | 23,712 |
NSL complex
|
2,230.41 | 14.12 | 6,211 | 15,768 |
histone H3K18 acetyltransferase activity
|
1,699.52 | 13.72 | 6,945 | 23,139 |
histone H3K27 acetyltransferase activity
|
1,691.97 | 13.63 | 6,901 | 23,095 |
histone H3K122 acetyltransferase activity
|
1,685.43 | 13.56 | 6,863 | 23,057 |
Totals | 317843 | 9773660 |
No co-occurrence statistics for GO:0000123 based on MANUAL annotations
The top 100 of 559 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone acetyltransferase complex
|
1,951.36 | 100.00 | 662 | 662 |
histone acetyltransferase activity
|
571.47 | 21.18 | 287 | 980 |
histone H3 acetyltransferase activity
|
767.48 | 11.65 | 94 | 239 |
chromatin DNA binding
|
270.22 | 11.43 | 262 | 1,892 |
histone H4K8 acetyltransferase activity
|
1,274.89 | 7.12 | 49 | 75 |
histone H4K5 acetyltransferase activity
|
1,210.34 | 7.08 | 49 | 79 |
histone H4K12 acetyltransferase activity
|
1,180.45 | 7.06 | 49 | 81 |
transcription regulator complex
|
147.66 | 6.77 | 260 | 3,436 |
histone H3K14 acetyltransferase activity
|
1,271.34 | 6.28 | 43 | 66 |
transcription coactivator activity
|
127.69 | 6.05 | 294 | 4,493 |
Totals | 3717 | 52961 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-08-28 | Added | RELATION | part of GO:0000785 (chromatin) |
2022-08-28 | Deleted | RELATION | part of GO:0005654 (nucleoplasm) |
2022-08-28 | Deleted | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044451 (obsolete nucleoplasm part) |
2019-09-12 | Added | RELATION | part of GO:0005654 (nucleoplasm) |
2015-06-18 | Added | RELATION | capable of GO:0004402 (histone acetyltransferase activity) |
2013-12-14 | Added | RELATION | is a GO:0031248 (protein acetyltransferase complex) |
2013-12-14 | Deleted | RELATION | is a GO:1902493 (acetyltransferase complex) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | histone acetyltransferase complex |
2001-04-03 | Updated | TERM | histone acetyltransferase complex |
2001-03-30 | Added | TERM | histone acetyltransferase complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-16 | Added | DEFINITION | A protein complex that possesses histone acetyltransferase activity. |
2008-05-16 | Deleted | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-15 | Added | DEFINITION | A protein complex that possesses histone acetyltransferase activity. |
2008-05-15 | Deleted | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-15 | Updated | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-14 | Updated | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-13 | Deleted | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-13 | Added | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2008-05-13 | Added | DEFINITION | A protein complex that possesses histone acetyltransferase activity. |
2008-05-12 | Deleted | DEFINITION | Complex that possesses histone acetyltransferase activity. |
2007-08-09 | Deleted | SYNONYM | histone acetylase complex |
2007-08-09 | Added | SYNONYM | histone acetylase complex |
2004-10-31 | Added | SYNONYM | histone acetylase complex |
2004-03-23 | Added | DEFINITION | Complex that possesses histone acetyltransferase activity. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-08-28 | Added | RELATION | part of GO:0000785 (chromatin) |
2022-08-28 | Deleted | RELATION | part of GO:0005654 (nucleoplasm) |
2022-08-28 | Deleted | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044451 (obsolete nucleoplasm part) |
2019-09-12 | Added | RELATION | part of GO:0005654 (nucleoplasm) |
2015-06-18 | Added | RELATION | capable of GO:0004402 (histone acetyltransferase activity) |
2013-12-14 | Added | RELATION | is a GO:0031248 (protein acetyltransferase complex) |
2013-12-14 | Deleted | RELATION | is a GO:1902493 (acetyltransferase complex) |
2013-11-28 | Added | RELATION | is a GO:1902493 (acetyltransferase complex) |
2013-11-28 | Deleted | RELATION | is a GO:1902494 (catalytic complex) |
2013-11-15 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-11-15 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2008-05-01 | Added | RELATION | is a GO:0043234 (protein complex) |
2008-05-01 | Deleted | RELATION | is a GO:0005667 (transcription regulator complex) |
2008-05-01 | Added | RELATION | is a GO:0044451 (obsolete nucleoplasm part) |
2008-04-01 | Updated | RELATION | is a GO:0005667 (transcription regulator complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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