GO:0000160
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phosphorelay signal transduction system
Biological Process
Definition (GO:0000160 GONUTS page)
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. PMID:9191038
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
histidyl-aspartyl phosphorelay | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000160
Child Term | Relationship to GO:0000160 |
---|---|
phosphorelay sensor kinase activity
|
part_of |
phosphorelay response regulator activity
|
part_of |
regulation of phosphorelay signal transduction system
|
regulates |
positive regulation of phosphorelay signal transduction system
|
positively_regulates |
ethylene-activated signaling pathway
|
is_a |
osmosensory signaling via phosphorelay pathway
|
is_a |
negative regulation of phosphorelay signal transduction system
|
negatively_regulates |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
---|---|
signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O14283 | 284812 | PRR1_SCHPO | GO:0000160 | They shouldn't match this GO term. Reported by InterPro (Typhaine Paysan-Lafosse) on 08/01/2020 | IPR001789 |
IEA Review | protein | Q8TFG6 | 284812 | PPK18_SCHPO | GO:0000160 | They shouldn't match this GO term. Reported by InterPro (Typhaine Paysan-Lafosse) on 08/01/2020 | IPR001789 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000673 | Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase |
InterPro | IPR001789 | Signal transduction response regulator, receiver domain |
InterPro | IPR001867 | OmpR/PhoB-type DNA-binding domain |
InterPro | IPR003755 | HPr(Ser) kinase/phosphorylase |
InterPro | IPR003852 | Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal |
InterPro | IPR004105 | Histidine kinase CheA-like, homodimeric domain |
InterPro | IPR006290 | Heavy metal sensor kinase |
InterPro | IPR008207 | Signal transduction histidine kinase, phosphotransfer (Hpt) domain |
InterPro | IPR008248 | Protein-glutamate methylesterase/protein-glutamine glutaminase, CheB type |
InterPro | IPR008358 | Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000160 based on ALL annotations
The top 100 of 2,624 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorelay signal transduction system
|
61.68 | 100.00 | 3,160,480 | 3,160,480 |
phosphorelay sensor kinase activity
|
59.96 | 44.74 | 1,432,236 | 1,473,219 |
phosphorelay response regulator activity
|
57.60 | 19.69 | 631,107 | 675,816 |
kinase activity
|
15.12 | 18.03 | 1,280,018 | 5,220,332 |
signal transduction
|
18.24 | 14.50 | 700,348 | 2,368,833 |
protein-DNA complex
|
43.96 | 13.74 | 459,791 | 645,092 |
transcription cis-regulatory region binding
|
16.36 | 10.38 | 460,781 | 1,737,394 |
regulation of DNA-templated transcription
|
7.41 | 9.90 | 1,138,197 | 9,472,174 |
DNA binding
|
4.24 | 6.05 | 1,062,540 | 15,456,294 |
protein dimerization activity
|
12.22 | 4.33 | 166,077 | 838,193 |
Totals | 15135492 | 296437670 |
No co-occurrence statistics for GO:0000160 based on MANUAL annotations
The top 100 of 188 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorelay signal transduction system
|
1,414.89 | 100.00 | 913 | 913 |
histidine phosphotransfer kinase activity
|
1,407.60 | 84.19 | 772 | 776 |
protein histidine kinase binding
|
1,359.34 | 44.73 | 416 | 433 |
cytokinin-activated signaling pathway
|
932.54 | 36.15 | 406 | 616 |
phosphorelay sensor kinase activity
|
862.13 | 32.79 | 379 | 622 |
phosphorelay response regulator activity
|
76.36 | 2.25 | 34 | 630 |
protein histidine kinase activity
|
332.92 | 1.26 | 12 | 51 |
osmosensory signaling via phosphorelay pathway
|
110.97 | 0.79 | 8 | 102 |
response to cytokinin
|
106.78 | 0.79 | 8 | 106 |
protein-DNA complex
|
11.90 | 0.48 | 10 | 1,189 |
Totals | 4452 | 575604 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_metagenomics | 111 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-09-14 | Deleted | SYNONYM | phosphorelay signal transduction system |
2020-02-28 | Deleted | XREF | MIPS_funcat:30.01.05.07 |
2020-02-28 | Deleted | XREF | MIPS_funcat:30.05.01.10 |
2019-05-04 | Added | XREF | MIPS_funcat:30.05.01.10 |
2019-05-04 | Added | XREF | MIPS_funcat:30.01.05.07 |
2014-08-29 | Added | RELATION | is a GO:0035556 (intracellular signal transduction) |
2014-08-29 | Deleted | RELATION | is a GO:0007165 (signal transduction) |
2013-04-18 | Updated | SUBSET | goslim_metagenomics |
2012-12-07 | Updated | TERM | phosphorelay signal transduction system |
2012-12-07 | Added | SYNONYM | phosphorelay signal transduction system |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-12-07 | Updated | TERM | phosphorelay signal transduction system |
2002-02-06 | Updated | TERM | two-component signal transduction system (phosphorelay) |
2001-04-03 | Updated | TERM | two-component signal transduction system (phosphorelay) |
2001-03-30 | Added | TERM | two-component signal transduction system (phosphorelay) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-09-14 | Deleted | SYNONYM | phosphorelay signal transduction system |
2012-12-07 | Added | SYNONYM | phosphorelay signal transduction system |
2008-05-13 | Added | DEFINITION | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
2008-05-12 | Deleted | DEFINITION | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
2007-08-09 | Deleted | SYNONYM | histidyl-aspartyl phosphorelay |
2007-08-09 | Added | SYNONYM | histidyl-aspartyl phosphorelay |
2005-07-29 | Added | SYNONYM | histidyl-aspartyl phosphorelay |
2005-07-28 | Updated | DEFINITION | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
2005-07-27 | Updated | DEFINITION | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
2004-08-20 | Updated | DEFINITION | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase that then acts as a phospho-donor to response regulator proteins; also known as histidyl-aspartyl phosphorelay. |
2001-08-06 | Added | DEFINITION | A conserved signal transduction system found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase that then acts as a phospho-donor to response regulator proteins; also known as histidyl-aspartyl phosphorelay. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-08-29 | Added | RELATION | is a GO:0035556 (intracellular signal transduction) |
2014-08-29 | Deleted | RELATION | is a GO:0007165 (signal transduction) |
2011-01-16 | Deleted | RELATION | is a GO:0023060 (obsolete signal transmission) |
2011-01-16 | Added | RELATION | is a GO:0007165 (signal transduction) |
2010-02-20 | Deleted | RELATION | is a GO:0007165 (signal transduction) |
2010-02-20 | Added | RELATION | is a GO:0023060 (obsolete signal transmission) |
2008-04-01 | Updated | RELATION | is a GO:0007165 (signal transduction) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:30.01.05.07 |
2020-02-28 | Deleted | XREF | MIPS_funcat:30.05.01.10 |
2019-05-04 | Added | XREF | MIPS_funcat:30.05.01.10 |
2019-05-04 | Added | XREF | MIPS_funcat:30.01.05.07 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-04-18 | Updated | SUBSET | goslim_metagenomics |
2012-02-17 | Added | SUBSET | goslim_metagenomics |
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