This term is obsolete.

GO:0001609 JSON

G protein-coupled adenosine receptor activity

Molecular Function

Definition (GO:0001609 GONUTS page)

Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. PMID:9755289

Secondary IDs

GO:0001610, GO:0001611, GO:0001612, GO:0001613, GO:0008501

5,397 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
A3 adenosine receptor activity, G-protein coupled narrow
G protein coupled A1 adenosine receptor activity narrow
G protein coupled A2A adenosine receptor activity narrow
adenosine receptor activity, G protein coupled exact
G protein coupled A3 adenosine receptor activity narrow
G-protein-coupled A1 adenosine receptor activity narrow
G-protein-coupled A2A adenosine receptor activity narrow
G-protein-coupled A2B adenosine receptor activity narrow
G-protein-coupled A3 adenosine receptor activity narrow
P1 receptor exact

Ancestor Chart

Ancestor chart for GO:0001609
Chart options
Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A2ARI4 10090 LGR4_MOUSE GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21693646
NOT-qualified manual protein B0BLW3 8364 LGR4_XENTR GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D4AC13 10116 LGR5_RAT GO:0004930 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein E5DHB5 8355 LGR5A_XENLA GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein E7FE13 7955 LGR4_DANRE GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F1MLX5 9913 LGR4_BOVIN GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F1MT22 9913 LGR5_BOVIN GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F7D3V9 8364 LGR5_XENTR GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein G3QNC0 9595 G3QNC0_GORGO GO:0007186 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8910290
NOT-qualified manual protein O15529 9606 GPR42_HUMAN GO:0004930 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12496283

Cross-references

Database ID Description
InterPro IPR001634 Adenosine receptor

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:16335 adenosine

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001609 based on ALL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term PR S% #Together #Compared
G protein-coupled adenosine receptor activity
36,628.86 100.00 5,322 5,322
G protein-coupled adenosine receptor signaling pathway
27,670.52 75.54 5,322 7,045
vasodilation
5,034.33 7.56 765 5,566
response to purine-containing compound
10,867.90 3.28 189 637
visual system development
36,628.86 1.65 88 88
regulation of microglial cell migration
36,217.30 1.65 88 89
negative regulation of long-term synaptic depression
19,073.02 1.63 88 169
negative regulation of mucus secretion
18,960.82 1.63 88 170
cell body membrane
15,571.69 1.62 88 207
adenylate cyclase-activating G protein-coupled receptor signaling pathway
604.16 1.60 1,795 108,827
Totals 35592 3184757
No co-occurrence statistics for GO:0001609 based on MANUAL annotations
The top 100 of 208 co-occurring terms
Co-occurring Term PR S% #Together #Compared
G protein-coupled adenosine receptor activity
21,529.98 100.00 60 60
G protein-coupled adenosine receptor signaling pathway
7,983.03 28.45 33 89
response to purine-containing compound
3,312.31 4.88 4 26
positive regulation of mast cell degranulation
1,957.27 4.00 4 44
visual system development
21,529.98 3.33 2 2
positive regulation of chronic inflammatory response to non-antigenic stimulus
21,529.98 3.33 2 2
regulation of microglial cell migration
10,764.99 3.23 2 4
regulation of norepinephrine secretion
5,382.50 3.03 2 8
positive regulation of monoatomic ion transport
3,588.33 2.86 2 12
purine nucleoside binding
3,075.71 2.78 2 14
Totals 317 15392

Change Log

Timestamp Action Category Detail
2020-02-07 Deleted RELATION is a GO:0035586 (purinergic receptor activity)
2018-09-08 Added SYNONYM G-protein coupled adenosine receptor activity
2018-09-08 Deleted SYNONYM G-protein-coupled adenosine receptor activity
2018-09-08 Updated TERM G protein-coupled adenosine receptor activity
2011-10-24 Added SYNONYM adenosine receptor activity, G-protein coupled
2011-10-24 Updated TERM G-protein coupled adenosine receptor activity
2011-10-24 Added DEFINITION Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 Deleted DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2010-10-24 Deleted RELATION is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity)
2010-10-24 Added RELATION part of GO:0001973 (G protein-coupled adenosine receptor signaling pathway)
Timestamp Action Category Detail
2018-09-08 Updated TERM G protein-coupled adenosine receptor activity
2011-10-24 Updated TERM G-protein coupled adenosine receptor activity
2003-03-25 Updated TERM adenosine receptor activity, G-protein coupled
2003-03-19 Updated TERM adenosine receptor, G-protein coupled activity
2002-01-15 Updated TERM adenosine receptor, G-protein coupled
2002-01-09 Added TERM adenosine receptor
Timestamp Action Category Detail
2018-09-08 Added SYNONYM G-protein coupled adenosine receptor activity
2018-09-08 Deleted SYNONYM G-protein-coupled adenosine receptor activity
2011-10-24 Added SYNONYM adenosine receptor activity, G-protein coupled
2011-10-24 Added DEFINITION Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 Deleted DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2010-10-24 Added SYNONYM P1 receptor
2008-05-13 Added DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-05-12 Deleted DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-03-11 Added DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-02-22 Added SYNONYM G protein coupled A2A adenosine receptor activity
2008-02-22 Added SYNONYM G protein coupled A1 adenosine receptor activity
2008-02-22 Added SYNONYM A3 adenosine receptor activity, G-protein coupled
2008-02-22 Added SYNONYM A3 adenosine receptor activity, G protein coupled
2008-02-22 Added SYNONYM A2B adenosine receptor activity, G-protein coupled
2008-02-22 Added SYNONYM A2B adenosine receptor activity, G protein coupled
2008-02-22 Added SYNONYM A2A adenosine receptor activity, G-protein coupled
2008-02-22 Added SYNONYM A2A adenosine receptor activity, G protein coupled
2008-02-22 Added SYNONYM A1 adenosine receptor activity, G-protein coupled
2008-02-22 Added SYNONYM A1 adenosine receptor activity, G protein coupled
2008-02-22 Added SYNONYM G-protein-coupled A3 adenosine receptor activity
2008-02-22 Added SYNONYM G-protein-coupled A2B adenosine receptor activity
2008-02-22 Added SYNONYM G-protein-coupled A2A adenosine receptor activity
2008-02-22 Added SYNONYM G-protein-coupled A1 adenosine receptor activity
2008-02-22 Added SYNONYM G protein coupled A3 adenosine receptor activity
2008-02-22 Added SYNONYM G protein coupled A2B adenosine receptor activity
2007-08-09 Deleted SYNONYM G-protein-coupled adenosine receptor activity
2007-08-09 Added SYNONYM G protein coupled adenosine receptor activity
2007-08-09 Added SYNONYM G-protein-coupled adenosine receptor activity
2007-08-09 Added SYNONYM adenosine nucleotide receptor
2007-08-09 Added SYNONYM adenosine receptor activity, G protein coupled
2007-08-09 Deleted SYNONYM adenosine nucleotide receptor
2007-08-09 Deleted SYNONYM adenosine receptor activity, G protein coupled
2007-08-09 Deleted SYNONYM G protein coupled adenosine receptor activity
2005-06-27 Added SYNONYM G protein coupled adenosine receptor activity
2005-06-27 Added SYNONYM G-protein-coupled adenosine receptor activity
2005-06-27 Added SYNONYM adenosine receptor activity, G protein coupled
2004-04-19 Added SYNONYM adenosine nucleotide receptor
2004-04-16 Deleted SYNONYM adenosine nucleotide receptor
2002-06-05 Added SYNONYM adenosine nucleotide receptor
Timestamp Action Category Detail
2020-02-07 Deleted RELATION is a GO:0035586 (purinergic receptor activity)
2010-10-24 Deleted RELATION is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity)
2010-10-24 Added RELATION part of GO:0001973 (G protein-coupled adenosine receptor signaling pathway)
2010-10-24 Added RELATION is a GO:0035586 (purinergic receptor activity)
2010-10-24 Added RELATION is a GO:0004930 (G protein-coupled receptor activity)
2008-04-01 Updated RELATION is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2008-02-22 Added SECONDARY GO:0001611 (A2A adenosine receptor activity, G-protein coupled)
2008-02-22 Added SECONDARY GO:0001613 (A3 adenosine receptor activity, G-protein coupled)
2008-02-22 Added SECONDARY GO:0001612 (A2B adenosine receptor activity, G-protein coupled)
2008-02-22 Added SECONDARY GO:0001610 (A1 adenosine receptor activity, G-protein coupled)
2002-06-05 Added SECONDARY GO:0008501 (adenosine nucleotide receptor)
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