GO:0001609
JSON
G protein-coupled adenosine receptor activity
Molecular Function
Definition (GO:0001609 GONUTS page)
Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. PMID:9755289
Secondary IDs
GO:0001610, GO:0001611, GO:0001612, GO:0001613, GO:0008501
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
A3 adenosine receptor activity, G-protein coupled | narrow |
G protein coupled A1 adenosine receptor activity | narrow |
G protein coupled A2A adenosine receptor activity | narrow |
adenosine receptor activity, G protein coupled | exact |
G protein coupled A3 adenosine receptor activity | narrow |
G-protein-coupled A1 adenosine receptor activity | narrow |
G-protein-coupled A2A adenosine receptor activity | narrow |
G-protein-coupled A2B adenosine receptor activity | narrow |
G-protein-coupled A3 adenosine receptor activity | narrow |
P1 receptor | exact |
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A2ARI4 | 10090 | LGR4_MOUSE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21693646 | |
NOT-qualified manual | protein | B0BLW3 | 8364 | LGR4_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D4AC13 | 10116 | LGR5_RAT | GO:0004930 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | E5DHB5 | 8355 | LGR5A_XENLA | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | E7FE13 | 7955 | LGR4_DANRE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MLX5 | 9913 | LGR4_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MT22 | 9913 | LGR5_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F7D3V9 | 8364 | LGR5_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | G3QNC0 | 9595 | G3QNC0_GORGO | GO:0007186 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8910290 | |
NOT-qualified manual | protein | O15529 | 9606 | GPR42_HUMAN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12496283 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001634 | Adenosine receptor |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:16335 | adenosine |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001609 based on ALL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
G protein-coupled adenosine receptor activity
|
36,628.86 | 100.00 | 5,322 | 5,322 |
G protein-coupled adenosine receptor signaling pathway
|
27,670.52 | 75.54 | 5,322 | 7,045 |
vasodilation
|
5,034.33 | 7.56 | 765 | 5,566 |
response to purine-containing compound
|
10,867.90 | 3.28 | 189 | 637 |
visual system development
|
36,628.86 | 1.65 | 88 | 88 |
regulation of microglial cell migration
|
36,217.30 | 1.65 | 88 | 89 |
negative regulation of long-term synaptic depression
|
19,073.02 | 1.63 | 88 | 169 |
negative regulation of mucus secretion
|
18,960.82 | 1.63 | 88 | 170 |
cell body membrane
|
15,571.69 | 1.62 | 88 | 207 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway
|
604.16 | 1.60 | 1,795 | 108,827 |
Totals | 35592 | 3184757 |
No co-occurrence statistics for GO:0001609 based on MANUAL annotations
The top 100 of 208 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
G protein-coupled adenosine receptor activity
|
21,529.98 | 100.00 | 60 | 60 |
G protein-coupled adenosine receptor signaling pathway
|
7,983.03 | 28.45 | 33 | 89 |
response to purine-containing compound
|
3,312.31 | 4.88 | 4 | 26 |
positive regulation of mast cell degranulation
|
1,957.27 | 4.00 | 4 | 44 |
visual system development
|
21,529.98 | 3.33 | 2 | 2 |
positive regulation of chronic inflammatory response to non-antigenic stimulus
|
21,529.98 | 3.33 | 2 | 2 |
regulation of microglial cell migration
|
10,764.99 | 3.23 | 2 | 4 |
regulation of norepinephrine secretion
|
5,382.50 | 3.03 | 2 | 8 |
positive regulation of monoatomic ion transport
|
3,588.33 | 2.86 | 2 | 12 |
purine nucleoside binding
|
3,075.71 | 2.78 | 2 | 14 |
Totals | 317 | 15392 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-07 | Deleted | RELATION | is a GO:0035586 (purinergic receptor activity) |
2018-09-08 | Added | SYNONYM | G-protein coupled adenosine receptor activity |
2018-09-08 | Deleted | SYNONYM | G-protein-coupled adenosine receptor activity |
2018-09-08 | Updated | TERM | G protein-coupled adenosine receptor activity |
2011-10-24 | Added | SYNONYM | adenosine receptor activity, G-protein coupled |
2011-10-24 | Updated | TERM | G-protein coupled adenosine receptor activity |
2011-10-24 | Added | DEFINITION | Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
2011-10-24 | Deleted | DEFINITION | Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
2010-10-24 | Deleted | RELATION | is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity) |
2010-10-24 | Added | RELATION | part of GO:0001973 (G protein-coupled adenosine receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-09-08 | Updated | TERM | G protein-coupled adenosine receptor activity |
2011-10-24 | Updated | TERM | G-protein coupled adenosine receptor activity |
2003-03-25 | Updated | TERM | adenosine receptor activity, G-protein coupled |
2003-03-19 | Updated | TERM | adenosine receptor, G-protein coupled activity |
2002-01-15 | Updated | TERM | adenosine receptor, G-protein coupled |
2002-01-09 | Added | TERM | adenosine receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-09-08 | Added | SYNONYM | G-protein coupled adenosine receptor activity |
2018-09-08 | Deleted | SYNONYM | G-protein-coupled adenosine receptor activity |
2011-10-24 | Added | SYNONYM | adenosine receptor activity, G-protein coupled |
2011-10-24 | Added | DEFINITION | Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
2011-10-24 | Deleted | DEFINITION | Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
2010-10-24 | Added | SYNONYM | P1 receptor |
2008-05-13 | Added | DEFINITION | Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
2008-03-11 | Added | DEFINITION | Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
2008-02-22 | Added | SYNONYM | G protein coupled A2A adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G protein coupled A1 adenosine receptor activity |
2008-02-22 | Added | SYNONYM | A3 adenosine receptor activity, G-protein coupled |
2008-02-22 | Added | SYNONYM | A3 adenosine receptor activity, G protein coupled |
2008-02-22 | Added | SYNONYM | A2B adenosine receptor activity, G-protein coupled |
2008-02-22 | Added | SYNONYM | A2B adenosine receptor activity, G protein coupled |
2008-02-22 | Added | SYNONYM | A2A adenosine receptor activity, G-protein coupled |
2008-02-22 | Added | SYNONYM | A2A adenosine receptor activity, G protein coupled |
2008-02-22 | Added | SYNONYM | A1 adenosine receptor activity, G-protein coupled |
2008-02-22 | Added | SYNONYM | A1 adenosine receptor activity, G protein coupled |
2008-02-22 | Added | SYNONYM | G-protein-coupled A3 adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G-protein-coupled A2B adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G-protein-coupled A2A adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G-protein-coupled A1 adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G protein coupled A3 adenosine receptor activity |
2008-02-22 | Added | SYNONYM | G protein coupled A2B adenosine receptor activity |
2007-08-09 | Deleted | SYNONYM | G-protein-coupled adenosine receptor activity |
2007-08-09 | Added | SYNONYM | G protein coupled adenosine receptor activity |
2007-08-09 | Added | SYNONYM | G-protein-coupled adenosine receptor activity |
2007-08-09 | Added | SYNONYM | adenosine nucleotide receptor |
2007-08-09 | Added | SYNONYM | adenosine receptor activity, G protein coupled |
2007-08-09 | Deleted | SYNONYM | adenosine nucleotide receptor |
2007-08-09 | Deleted | SYNONYM | adenosine receptor activity, G protein coupled |
2007-08-09 | Deleted | SYNONYM | G protein coupled adenosine receptor activity |
2005-06-27 | Added | SYNONYM | G protein coupled adenosine receptor activity |
2005-06-27 | Added | SYNONYM | G-protein-coupled adenosine receptor activity |
2005-06-27 | Added | SYNONYM | adenosine receptor activity, G protein coupled |
2004-04-19 | Added | SYNONYM | adenosine nucleotide receptor |
2004-04-16 | Deleted | SYNONYM | adenosine nucleotide receptor |
2002-06-05 | Added | SYNONYM | adenosine nucleotide receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-07 | Deleted | RELATION | is a GO:0035586 (purinergic receptor activity) |
2010-10-24 | Deleted | RELATION | is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity) |
2010-10-24 | Added | RELATION | part of GO:0001973 (G protein-coupled adenosine receptor signaling pathway) |
2010-10-24 | Added | RELATION | is a GO:0035586 (purinergic receptor activity) |
2010-10-24 | Added | RELATION | is a GO:0004930 (G protein-coupled receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0045028 (G protein-coupled purinergic nucleotide receptor activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-02-22 | Added | SECONDARY | GO:0001611 (A2A adenosine receptor activity, G-protein coupled) |
2008-02-22 | Added | SECONDARY | GO:0001613 (A3 adenosine receptor activity, G-protein coupled) |
2008-02-22 | Added | SECONDARY | GO:0001612 (A2B adenosine receptor activity, G-protein coupled) |
2008-02-22 | Added | SECONDARY | GO:0001610 (A1 adenosine receptor activity, G-protein coupled) |
2002-06-05 | Added | SECONDARY | GO:0008501 (adenosine nucleotide receptor) |
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