This term is obsolete.

GO:0003746 JSON

translation elongation factor activity

Molecular Function

Definition (GO:0003746 GONUTS page)

Functions in chain elongation during polypeptide synthesis at the ribosome.

Secondary IDs

GO:0008182, GO:0008183

582,845 annotations

Ancestor Chart

Ancestor chart for GO:0003746
Chart options
Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0003746 translation elongation factor activity Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2K9J3 10116 A0A0G2K9J3_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZWL9 10116 A0A8I5ZWL9_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AJA2 10116 A0A8I6AJA2_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JIT1 10116 A6JIT1_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JIT2 10116 A6JIT2_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JIT3 10116 A6JIT3_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4ABV1 10116 D4ABV1_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q5BJP6 10116 RRF2M_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q5M809 10116 Q5M809_RAT GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q969S9 9606 RRF2M_HUMAN GO:0003746 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19716793

Cross-references

Database ID Description
InterPro IPR001059 Translation elongation factor P/YeiP, central
InterPro IPR001326 Translation elongation factor EF1B, beta/delta chains, conserved site
InterPro IPR001662 Elongation factor 1B gamma, C-terminal
InterPro IPR001816 Translation elongation factor EFTs/EF1B
InterPro IPR001884 Translation elongation factor IF5A-like
InterPro IPR004535 Translation elongation factor, selenocysteine-specific
InterPro IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal
InterPro IPR004540 Translation elongation factor EFG/EF2
InterPro IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle
InterPro IPR004542 Translation elongation factor EF1B, beta chain, archaeal

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0016147 obsolete protein-synthesizing GTPase activity, elongation consider GO:0003746

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0003746 based on ALL annotations
The top 100 of 2,034 co-occurring terms
Co-occurring Term PR S% #Together #Compared
translation elongation factor activity
340.98 100.00 581,134 581,134
translational elongation
335.05 97.53 576,714 586,925
GTPase activity
66.65 16.66 308,300 1,577,317
GTP binding
46.09 12.34 341,129 2,523,530
ribosome disassembly
171.60 10.77 70,030 139,154
regulation of DNA-templated transcription elongation
170.57 9.34 59,842 119,626
RNA polymerase binding
257.87 9.33 55,871 73,877
DNA-templated transcription elongation
157.06 9.18 59,750 129,716
peptide biosynthetic process
338.24 8.07 46,937 47,317
positive regulation of translation
167.32 6.79 42,433 86,472
Totals 3381757 181436644
No co-occurrence statistics for GO:0003746 based on MANUAL annotations
The top 100 of 228 co-occurring terms
Co-occurring Term PR S% #Together #Compared
translation elongation factor activity
774.72 100.00 1,822 1,822
translational elongation
576.74 50.27 1,107 1,487
mitochondrial translational elongation
690.74 27.07 510 572
ribosome binding
62.20 5.10 224 2,790
GTPase activity
37.93 4.58 761 15,544
translation
41.34 4.36 351 6,577
ribonucleoprotein complex
39.93 3.81 232 4,501
selenocysteine incorporation
245.41 2.64 51 161
eukaryotic translation elongation factor 1 complex
659.94 1.26 23 27
cytoplasmic translational elongation
130.40 0.89 17 101
Totals 6393 540091

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2019-04-01 Added XREF Reactome:R-HSA-192841
2019-04-01 Added XREF Reactome:R-HSA-192704
2019-04-01 Deleted XREF reactome:R-HSA-192841
2019-04-01 Deleted XREF reactome:R-HSA-192704
2018-12-11 Added XREF reactome:R-HSA-192841
2018-12-11 Added XREF reactome:R-HSA-192704
2010-06-15 Added RELATION part of GO:0006414 (translational elongation)
2010-06-14 Deleted RELATION part of GO:0006414 (translational elongation)
2010-06-08 Added RELATION part of GO:0006414 (translational elongation)
Timestamp Action Category Detail
2003-03-19 Updated TERM translation elongation factor activity
2002-02-06 Updated TERM translation elongation factor
2001-04-03 Updated TERM translation elongation factor
2001-03-30 Added TERM translation elongation factor
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Functions in chain elongation during polypeptide synthesis at the ribosome.
2008-05-12 Deleted DEFINITION Functions in chain elongation during polypeptide synthesis at the ribosome.
2007-07-11 Deleted SYNONYM protein-synthesizing GTPase activity, elongation
2005-08-10 Added SYNONYM protein-synthesizing GTPase activity, elongation
2003-07-24 Updated DEFINITION Functions in chain elongation during polypeptide synthesis at the ribosome.
2002-11-27 Updated DEFINITION Any of a group of soluble proteins required for chain elongation during polypeptide synthesis at the ribosome.
2001-08-06 Added DEFINITION any member of a group of soluble proteins required for chain elongation during polypeptide synthesis at the ribosome.
Timestamp Action Category Detail
2010-06-15 Added RELATION part of GO:0006414 (translational elongation)
2010-06-14 Deleted RELATION part of GO:0006414 (translational elongation)
2010-06-08 Added RELATION part of GO:0006414 (translational elongation)
2008-04-01 Updated RELATION is a GO:0008135 (translation factor activity, RNA binding)
Timestamp Action Category Detail
2019-04-01 Added XREF Reactome:R-HSA-192841
2019-04-01 Added XREF Reactome:R-HSA-192704
2019-04-01 Deleted XREF reactome:R-HSA-192841
2019-04-01 Deleted XREF reactome:R-HSA-192704
2018-12-11 Added XREF reactome:R-HSA-192841
2018-12-11 Added XREF reactome:R-HSA-192704
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.