GO:0004307
JSON
ethanolaminephosphotransferase activity
Molecular Function
Definition (GO:0004307 GONUTS page)
Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity | related |
diacylglycerol ethanolaminephosphotransferase activity | related |
phosphorylethanolamine-glyceride transferase activity | related |
EPT | related |
CDPethanolamine diglyceride phosphotransferase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.8.1 | |
MetaCyc | ETHANOLAMINEPHOSPHOTRANSFERASE-RXN | |
RHEA | 32943 | |
Reactome | R-HSA-1482962 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57876 | CDP-ethanolamine(1-) |
has_participant | CHEBI | CHEBI:17815 | 1,2-diacyl-sn-glycerol |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:60377 | cytidine 5'-monophosphate(2-) |
has_participant | CHEBI | CHEBI:64612 | 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004307 based on ALL annotations
The top 93 of 93 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ethanolaminephosphotransferase activity
|
39,798.13 | 100.00 | 4,979 | 4,979 |
diacylglycerol cholinephosphotransferase activity
|
25,150.21 | 42.60 | 2,821 | 4,464 |
CDP-choline pathway
|
5,861.47 | 13.24 | 2,821 | 19,154 |
phosphatidylethanolamine biosynthetic process
|
2,956.56 | 7.42 | 4,864 | 65,474 |
lipid biosynthetic process
|
643.88 | 1.62 | 4,855 | 300,087 |
nuclear membrane
|
638.34 | 1.53 | 1,301 | 81,112 |
phosphotransferase activity, for other substituted phosphate groups
|
579.60 | 1.45 | 4,614 | 316,822 |
phospholipid biosynthetic process
|
316.66 | 0.80 | 4,610 | 579,385 |
ether lipid biosynthetic process
|
478.52 | 0.66 | 71 | 5,905 |
phosphatidylcholine biosynthetic process
|
225.21 | 0.46 | 118 | 20,852 |
Totals | 54630 | 306072475 |
No co-occurrence statistics for GO:0004307 based on MANUAL annotations
The top 28 of 28 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ethanolaminephosphotransferase activity
|
13,704.20 | 100.00 | 103 | 103 |
diacylglycerol cholinephosphotransferase activity
|
4,685.95 | 25.85 | 53 | 155 |
phosphatidylethanolamine biosynthetic process
|
1,702.28 | 12.36 | 99 | 797 |
ether lipid biosynthetic process
|
595.83 | 2.09 | 4 | 92 |
sphingomyelin biosynthetic process
|
279.68 | 1.01 | 2 | 98 |
mitotic nuclear membrane biogenesis
|
2,284.03 | 0.93 | 1 | 6 |
myelination
|
112.56 | 0.68 | 4 | 487 |
phosphatidylcholine biosynthetic process
|
107.70 | 0.66 | 4 | 509 |
endoplasmic reticulum membrane
|
71.30 | 0.52 | 97 | 18,644 |
ceramide cholinephosphotransferase activity
|
91.97 | 0.50 | 2 | 298 |
Totals | 498 | 610362 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | CDPethanolamine diglyceride phosphotransferase activity |
2020-10-08 | Added | SYNONYM | CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphorylethanolamine-glyceride transferase activity |
2020-10-08 | Deleted | SYNONYM | diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CDPethanolamine diglyceride phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Added | SYNONYM | diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Added | SYNONYM | phosphorylethanolamine-glyceride transferase activity |
2020-03-30 | Added | XREF | RHEA:32943 |
2020-03-30 | Deleted | XREF | RHEA:14596 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | ethanolaminephosphotransferase activity |
2002-02-06 | Updated | TERM | ethanolaminephosphotransferase |
2001-04-03 | Updated | TERM | ethanolaminephosphotransferase |
2001-03-30 | Added | TERM | ethanolaminephosphotransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | CDPethanolamine diglyceride phosphotransferase activity |
2020-10-08 | Added | SYNONYM | CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphorylethanolamine-glyceride transferase activity |
2020-10-08 | Deleted | SYNONYM | diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CDPethanolamine diglyceride phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Added | SYNONYM | diacylglycerol ethanolaminephosphotransferase activity |
2020-10-08 | Added | SYNONYM | phosphorylethanolamine-glyceride transferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine. |
2007-11-08 | Added | SYNONYM | CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity |
2007-11-08 | Added | SYNONYM | CDPethanolamine diglyceride phosphotransferase activity |
2007-11-08 | Added | SYNONYM | diacylglycerol ethanolaminephosphotransferase activity |
2007-11-08 | Added | SYNONYM | phosphorylethanolamine-glyceride transferase activity |
2007-11-08 | Added | SYNONYM | EPT |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0017169 (CDP-alcohol phosphatidyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-30 | Added | XREF | RHEA:32943 |
2020-03-30 | Deleted | XREF | RHEA:14596 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1482962 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1482962 |
2018-12-11 | Added | XREF | reactome:R-HSA-1482962 |
2011-09-16 | Added | XREF | RHEA:14596 |
2003-10-27 | Added | XREF | MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN |
2001-03-30 | Added | XREF | EC:2.7.8.1 |
Timestamp | Action | Category | Detail |
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