This term is obsolete.

GO:0004307 JSON

ethanolaminephosphotransferase activity

Molecular Function

Definition (GO:0004307 GONUTS page)

Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.

5,031 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity related
diacylglycerol ethanolaminephosphotransferase activity related
phosphorylethanolamine-glyceride transferase activity related
EPT related
CDPethanolamine diglyceride phosphotransferase activity related

Ancestor Chart

Ancestor chart for GO:0004307
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.7.8.1
MetaCyc ETHANOLAMINEPHOSPHOTRANSFERASE-RXN
RHEA 32943
Reactome R-HSA-1482962

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57876 CDP-ethanolamine(1-)
has_participant CHEBI CHEBI:17815 1,2-diacyl-sn-glycerol
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:60377 cytidine 5'-monophosphate(2-)
has_participant CHEBI CHEBI:64612 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004307 based on ALL annotations
The top 93 of 93 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ethanolaminephosphotransferase activity
39,798.13 100.00 4,979 4,979
diacylglycerol cholinephosphotransferase activity
25,150.21 42.60 2,821 4,464
CDP-choline pathway
5,861.47 13.24 2,821 19,154
phosphatidylethanolamine biosynthetic process
2,956.56 7.42 4,864 65,474
lipid biosynthetic process
643.88 1.62 4,855 300,087
nuclear membrane
638.34 1.53 1,301 81,112
phosphotransferase activity, for other substituted phosphate groups
579.60 1.45 4,614 316,822
phospholipid biosynthetic process
316.66 0.80 4,610 579,385
ether lipid biosynthetic process
478.52 0.66 71 5,905
phosphatidylcholine biosynthetic process
225.21 0.46 118 20,852
Totals 54630 306072475
No co-occurrence statistics for GO:0004307 based on MANUAL annotations
The top 28 of 28 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ethanolaminephosphotransferase activity
13,704.20 100.00 103 103
diacylglycerol cholinephosphotransferase activity
4,685.95 25.85 53 155
phosphatidylethanolamine biosynthetic process
1,702.28 12.36 99 797
ether lipid biosynthetic process
595.83 2.09 4 92
sphingomyelin biosynthetic process
279.68 1.01 2 98
mitotic nuclear membrane biogenesis
2,284.03 0.93 1 6
myelination
112.56 0.68 4 487
phosphatidylcholine biosynthetic process
107.70 0.66 4 509
endoplasmic reticulum membrane
71.30 0.52 97 18,644
ceramide cholinephosphotransferase activity
91.97 0.50 2 298
Totals 498 610362

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM CDPethanolamine diglyceride phosphotransferase activity
2020-10-08 Added SYNONYM CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Deleted SYNONYM phosphorylethanolamine-glyceride transferase activity
2020-10-08 Deleted SYNONYM diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Deleted SYNONYM CDPethanolamine diglyceride phosphotransferase activity
2020-10-08 Deleted SYNONYM CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Added SYNONYM diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Added SYNONYM phosphorylethanolamine-glyceride transferase activity
2020-03-30 Added XREF RHEA:32943
2020-03-30 Deleted XREF RHEA:14596
Timestamp Action Category Detail
2003-03-19 Updated TERM ethanolaminephosphotransferase activity
2002-02-06 Updated TERM ethanolaminephosphotransferase
2001-04-03 Updated TERM ethanolaminephosphotransferase
2001-03-30 Added TERM ethanolaminephosphotransferase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM CDPethanolamine diglyceride phosphotransferase activity
2020-10-08 Added SYNONYM CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Deleted SYNONYM phosphorylethanolamine-glyceride transferase activity
2020-10-08 Deleted SYNONYM diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Deleted SYNONYM CDPethanolamine diglyceride phosphotransferase activity
2020-10-08 Deleted SYNONYM CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Added SYNONYM diacylglycerol ethanolaminephosphotransferase activity
2020-10-08 Added SYNONYM phosphorylethanolamine-glyceride transferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
2007-11-08 Added SYNONYM CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity
2007-11-08 Added SYNONYM CDPethanolamine diglyceride phosphotransferase activity
2007-11-08 Added SYNONYM diacylglycerol ethanolaminephosphotransferase activity
2007-11-08 Added SYNONYM phosphorylethanolamine-glyceride transferase activity
2007-11-08 Added SYNONYM EPT
2002-11-27 Added DEFINITION Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0017169 (CDP-alcohol phosphatidyltransferase activity)
Timestamp Action Category Detail
2020-03-30 Added XREF RHEA:32943
2020-03-30 Deleted XREF RHEA:14596
2019-04-01 Deleted XREF reactome:R-HSA-1482962
2019-04-01 Added XREF Reactome:R-HSA-1482962
2018-12-11 Added XREF reactome:R-HSA-1482962
2011-09-16 Added XREF RHEA:14596
2003-10-27 Added XREF MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN
2001-03-30 Added XREF EC:2.7.8.1
Timestamp Action Category Detail
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