GO:0004515
JSON
nicotinate-nucleotide adenylyltransferase activity
Molecular Function
Definition (GO:0004515 GONUTS page)
Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
nicotinate mononucleotide adenylyltransferase activity | related |
deamidonicotinamide adenine dinucleotide pyrophosphorylase activity | related |
deamido-NAD(+) pyrophosphorylase activity | related |
deamido-NAD(+) diphosphorylase activity | related |
deamido-NAD+ pyrophosphorylase activity | related |
ATP:nicotinate-ribonucleotide adenylyltransferase activity | related |
ATP:nicotinate-nucleotide adenylyltransferase activity | exact |
NaMN-ATase activity | related |
nicotinic acid mononucleotide adenylyltransferase | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q4H4F3 | 1397 | BTRD_NIACI | GO:0016779 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17226887 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.7.18 | |
InterPro | IPR045094 | Nicotinamide/nicotinate mononucleotide adenylyltransferase, eukaryotic |
MetaCyc | NICONUCADENYLYLTRAN-RXN | |
RHEA | 22860 | |
Reactome | R-HSA-197235 | |
Reactome | R-HSA-200474 | |
Reactome | R-HSA-200512 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:58437 | deamido-NAD(2-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:57502 | nicotinate D-ribonucleotide(2-) |
has_participant | CHEBI | CHEBI:33019 | diphosphate(3-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004515 based on ALL annotations
The top 100 of 389 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nicotinate-nucleotide adenylyltransferase activity
|
4,406.77 | 100.00 | 44,966 | 44,966 |
adenylyltransferase activity
|
2,764.67 | 60.25 | 42,195 | 67,257 |
pyridine nucleotide biosynthetic process
|
770.91 | 17.35 | 42,899 | 245,223 |
nucleotide biosynthetic process
|
703.45 | 15.80 | 42,176 | 264,212 |
NAD biosynthetic process
|
665.19 | 15.09 | 44,874 | 297,281 |
nicotinamide-nucleotide adenylyltransferase activity
|
1,928.29 | 13.02 | 7,034 | 16,075 |
nucleotidyltransferase activity
|
99.53 | 2.26 | 43,660 | 1,933,012 |
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
|
80.11 | 0.69 | 497 | 27,338 |
cytoplasmic vesicle membrane
|
38.02 | 0.60 | 883 | 102,347 |
protein ADP-ribosyltransferase-substrate adaptor activity
|
2,298.15 | 0.43 | 194 | 372 |
Totals | 322266 | 56979337 |
No co-occurrence statistics for GO:0004515 based on MANUAL annotations
The top 100 of 131 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nicotinate-nucleotide adenylyltransferase activity
|
7,238.63 | 100.00 | 195 | 195 |
nicotinamide-nucleotide adenylyltransferase activity
|
5,252.09 | 72.01 | 193 | 266 |
NAD biosynthetic process
|
2,494.74 | 34.34 | 193 | 560 |
protein ADP-ribosyltransferase-substrate adaptor activity
|
3,217.17 | 5.71 | 12 | 27 |
negative regulation of apoptotic DNA fragmentation
|
2,285.88 | 2.88 | 6 | 19 |
ATP generation from poly-ADP-D-ribose
|
420.31 | 2.64 | 9 | 155 |
response to tumor necrosis factor
|
241.29 | 1.47 | 5 | 150 |
dendritic spine maintenance
|
332.81 | 1.44 | 4 | 87 |
nucleotide biosynthetic process
|
868.64 | 1.38 | 3 | 25 |
photoreceptor cell maintenance
|
83.44 | 0.74 | 4 | 347 |
Totals | 811 | 156791 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Added | DEFINITION | Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate. |
2024-12-23 | Deleted | DEFINITION | Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. |
2020-10-08 | Deleted | SYNONYM | deamidonicotinamide adenine dinucleotide pyrophosphorylase activity |
2020-10-08 | Deleted | SYNONYM | deamido-NAD(+) diphosphorylase activity |
2020-10-08 | Deleted | SYNONYM | deamido-NAD(+) pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | ATP:nicotinate-ribonucleotide adenylyltransferase activity |
2020-10-08 | Added | SYNONYM | deamidonicotinamide adenine dinucleotide pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD(+) diphosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD+ pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD(+) pyrophosphorylase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | nicotinate-nucleotide adenylyltransferase activity |
2002-02-06 | Updated | TERM | nicotinate-nucleotide adenylyltransferase |
2001-04-03 | Updated | TERM | nicotinate-nucleotide adenylyltransferase |
2001-03-30 | Added | TERM | nicotinate-nucleotide adenylyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Added | DEFINITION | Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate. |
2024-12-23 | Deleted | DEFINITION | Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. |
2020-10-08 | Deleted | SYNONYM | deamidonicotinamide adenine dinucleotide pyrophosphorylase activity |
2020-10-08 | Deleted | SYNONYM | deamido-NAD(+) diphosphorylase activity |
2020-10-08 | Deleted | SYNONYM | deamido-NAD(+) pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | ATP:nicotinate-ribonucleotide adenylyltransferase activity |
2020-10-08 | Added | SYNONYM | deamidonicotinamide adenine dinucleotide pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD(+) diphosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD+ pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | deamido-NAD(+) pyrophosphorylase activity |
2020-10-08 | Added | SYNONYM | nicotinate mononucleotide adenylyltransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:nicotinate-ribonucleotide adenylyltransferase activity |
2020-10-08 | Added | SYNONYM | NaMN-ATase activity |
2020-10-08 | Deleted | SYNONYM | nicotinate mononucleotide adenylyltransferase activity |
2020-10-08 | Deleted | SYNONYM | NaMN-ATase activity |
2020-10-08 | Deleted | SYNONYM | deamido-NAD+ pyrophosphorylase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. |
2007-11-08 | Added | SYNONYM | nicotinate mononucleotide adenylyltransferase activity |
2007-11-08 | Added | SYNONYM | ATP:nicotinate-ribonucleotide adenylyltransferase activity |
2007-11-08 | Added | SYNONYM | NaMN-ATase activity |
2007-11-08 | Added | SYNONYM | deamido-NAD+ pyrophosphorylase activity |
2007-11-08 | Added | SYNONYM | deamidonicotinamide adenine dinucleotide pyrophosphorylase activity |
2007-09-06 | Added | SYNONYM | deamido-NAD(+) diphosphorylase activity |
2007-09-06 | Added | SYNONYM | deamido-NAD(+) pyrophosphorylase activity |
2007-08-09 | Deleted | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2007-08-09 | Deleted | SYNONYM | ATP:nicotinate-nucleotide adenylyltransferase activity |
2007-08-09 | Added | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2007-08-09 | Added | SYNONYM | ATP:nicotinate-nucleotide adenylyltransferase activity |
2005-10-24 | Added | SYNONYM | ATP:nicotinate-nucleotide adenylyltransferase activity |
2004-04-19 | Added | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2004-04-16 | Deleted | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2003-10-27 | Added | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2003-08-21 | Deleted | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. |
2002-03-17 | Added | SYNONYM | nicotinic acid mononucleotide adenylyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-04-29 | Deleted | RELATION | is a GO:0016779 (nucleotidyltransferase activity) |
2009-04-29 | Added | RELATION | is a GO:0070566 (adenylyltransferase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016779 (nucleotidyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-200512 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-197235 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-200474 |
2019-04-01 | Added | XREF | Reactome:R-HSA-197235 |
2019-04-01 | Added | XREF | Reactome:R-HSA-200474 |
2019-04-01 | Added | XREF | Reactome:R-HSA-200512 |
2018-12-11 | Added | XREF | reactome:R-HSA-200512 |
2018-12-11 | Added | XREF | reactome:R-HSA-197235 |
2018-12-11 | Added | XREF | reactome:R-HSA-200474 |
2018-07-13 | Added | XREF | RHEA:22860 |
2018-07-13 | Deleted | XREF | RHEA:22863 |
2011-09-16 | Added | XREF | RHEA:22863 |
2003-10-27 | Added | XREF | MetaCyc:NICONUCADENYLYLTRAN-RXN |
2001-03-30 | Added | XREF | EC:2.7.7.18 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link