This term is obsolete.

GO:0004515 JSON

nicotinate-nucleotide adenylyltransferase activity

Molecular Function

Definition (GO:0004515 GONUTS page)

Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.

45,150 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
nicotinate mononucleotide adenylyltransferase activity related
deamidonicotinamide adenine dinucleotide pyrophosphorylase activity related
deamido-NAD(+) pyrophosphorylase activity related
deamido-NAD(+) diphosphorylase activity related
deamido-NAD+ pyrophosphorylase activity related
ATP:nicotinate-ribonucleotide adenylyltransferase activity related
ATP:nicotinate-nucleotide adenylyltransferase activity exact
NaMN-ATase activity related
nicotinic acid mononucleotide adenylyltransferase narrow

Ancestor Chart

Ancestor chart for GO:0004515
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q4H4F3 1397 BTRD_NIACI GO:0016779 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17226887
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.7.7.18
InterPro IPR045094 Nicotinamide/nicotinate mononucleotide adenylyltransferase, eukaryotic
MetaCyc NICONUCADENYLYLTRAN-RXN
RHEA 22860
Reactome R-HSA-197235
Reactome R-HSA-200474
Reactome R-HSA-200512

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:58437 deamido-NAD(2-)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:57502 nicotinate D-ribonucleotide(2-)
has_participant CHEBI CHEBI:33019 diphosphate(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004515 based on ALL annotations
The top 100 of 389 co-occurring terms
Co-occurring Term PR S% #Together #Compared
nicotinate-nucleotide adenylyltransferase activity
4,406.77 100.00 44,966 44,966
adenylyltransferase activity
2,764.67 60.25 42,195 67,257
pyridine nucleotide biosynthetic process
770.91 17.35 42,899 245,223
nucleotide biosynthetic process
703.45 15.80 42,176 264,212
NAD biosynthetic process
665.19 15.09 44,874 297,281
nicotinamide-nucleotide adenylyltransferase activity
1,928.29 13.02 7,034 16,075
nucleotidyltransferase activity
99.53 2.26 43,660 1,933,012
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
80.11 0.69 497 27,338
cytoplasmic vesicle membrane
38.02 0.60 883 102,347
protein ADP-ribosyltransferase-substrate adaptor activity
2,298.15 0.43 194 372
Totals 322266 56979337
No co-occurrence statistics for GO:0004515 based on MANUAL annotations
The top 100 of 131 co-occurring terms
Co-occurring Term PR S% #Together #Compared
nicotinate-nucleotide adenylyltransferase activity
7,238.63 100.00 195 195
nicotinamide-nucleotide adenylyltransferase activity
5,252.09 72.01 193 266
NAD biosynthetic process
2,494.74 34.34 193 560
protein ADP-ribosyltransferase-substrate adaptor activity
3,217.17 5.71 12 27
negative regulation of apoptotic DNA fragmentation
2,285.88 2.88 6 19
ATP generation from poly-ADP-D-ribose
420.31 2.64 9 155
response to tumor necrosis factor
241.29 1.47 5 150
dendritic spine maintenance
332.81 1.44 4 87
nucleotide biosynthetic process
868.64 1.38 3 25
photoreceptor cell maintenance
83.44 0.74 4 347
Totals 811 156791

Change Log

Timestamp Action Category Detail
2024-12-23 Added DEFINITION Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.
2024-12-23 Deleted DEFINITION Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
2020-10-08 Deleted SYNONYM deamidonicotinamide adenine dinucleotide pyrophosphorylase activity
2020-10-08 Deleted SYNONYM deamido-NAD(+) diphosphorylase activity
2020-10-08 Deleted SYNONYM deamido-NAD(+) pyrophosphorylase activity
2020-10-08 Added SYNONYM ATP:nicotinate-ribonucleotide adenylyltransferase activity
2020-10-08 Added SYNONYM deamidonicotinamide adenine dinucleotide pyrophosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD(+) diphosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD+ pyrophosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD(+) pyrophosphorylase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM nicotinate-nucleotide adenylyltransferase activity
2002-02-06 Updated TERM nicotinate-nucleotide adenylyltransferase
2001-04-03 Updated TERM nicotinate-nucleotide adenylyltransferase
2001-03-30 Added TERM nicotinate-nucleotide adenylyltransferase
Timestamp Action Category Detail
2024-12-23 Added DEFINITION Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.
2024-12-23 Deleted DEFINITION Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
2020-10-08 Deleted SYNONYM deamidonicotinamide adenine dinucleotide pyrophosphorylase activity
2020-10-08 Deleted SYNONYM deamido-NAD(+) diphosphorylase activity
2020-10-08 Deleted SYNONYM deamido-NAD(+) pyrophosphorylase activity
2020-10-08 Added SYNONYM ATP:nicotinate-ribonucleotide adenylyltransferase activity
2020-10-08 Added SYNONYM deamidonicotinamide adenine dinucleotide pyrophosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD(+) diphosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD+ pyrophosphorylase activity
2020-10-08 Added SYNONYM deamido-NAD(+) pyrophosphorylase activity
2020-10-08 Added SYNONYM nicotinate mononucleotide adenylyltransferase activity
2020-10-08 Deleted SYNONYM ATP:nicotinate-ribonucleotide adenylyltransferase activity
2020-10-08 Added SYNONYM NaMN-ATase activity
2020-10-08 Deleted SYNONYM nicotinate mononucleotide adenylyltransferase activity
2020-10-08 Deleted SYNONYM NaMN-ATase activity
2020-10-08 Deleted SYNONYM deamido-NAD+ pyrophosphorylase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
2007-11-08 Added SYNONYM nicotinate mononucleotide adenylyltransferase activity
2007-11-08 Added SYNONYM ATP:nicotinate-ribonucleotide adenylyltransferase activity
2007-11-08 Added SYNONYM NaMN-ATase activity
2007-11-08 Added SYNONYM deamido-NAD+ pyrophosphorylase activity
2007-11-08 Added SYNONYM deamidonicotinamide adenine dinucleotide pyrophosphorylase activity
2007-09-06 Added SYNONYM deamido-NAD(+) diphosphorylase activity
2007-09-06 Added SYNONYM deamido-NAD(+) pyrophosphorylase activity
2007-08-09 Deleted SYNONYM nicotinic acid mononucleotide adenylyltransferase
2007-08-09 Deleted SYNONYM ATP:nicotinate-nucleotide adenylyltransferase activity
2007-08-09 Added SYNONYM nicotinic acid mononucleotide adenylyltransferase
2007-08-09 Added SYNONYM ATP:nicotinate-nucleotide adenylyltransferase activity
2005-10-24 Added SYNONYM ATP:nicotinate-nucleotide adenylyltransferase activity
2004-04-19 Added SYNONYM nicotinic acid mononucleotide adenylyltransferase
2004-04-16 Deleted SYNONYM nicotinic acid mononucleotide adenylyltransferase
2003-10-27 Added SYNONYM nicotinic acid mononucleotide adenylyltransferase
2003-08-21 Deleted SYNONYM nicotinic acid mononucleotide adenylyltransferase
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
2002-03-17 Added SYNONYM nicotinic acid mononucleotide adenylyltransferase
Timestamp Action Category Detail
2009-04-29 Deleted RELATION is a GO:0016779 (nucleotidyltransferase activity)
2009-04-29 Added RELATION is a GO:0070566 (adenylyltransferase activity)
2008-04-01 Updated RELATION is a GO:0016779 (nucleotidyltransferase activity)
Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-200512
2019-04-01 Deleted XREF reactome:R-HSA-197235
2019-04-01 Deleted XREF reactome:R-HSA-200474
2019-04-01 Added XREF Reactome:R-HSA-197235
2019-04-01 Added XREF Reactome:R-HSA-200474
2019-04-01 Added XREF Reactome:R-HSA-200512
2018-12-11 Added XREF reactome:R-HSA-200512
2018-12-11 Added XREF reactome:R-HSA-197235
2018-12-11 Added XREF reactome:R-HSA-200474
2018-07-13 Added XREF RHEA:22860
2018-07-13 Deleted XREF RHEA:22863
2011-09-16 Added XREF RHEA:22863
2003-10-27 Added XREF MetaCyc:NICONUCADENYLYLTRAN-RXN
2001-03-30 Added XREF EC:2.7.7.18
Timestamp Action Category Detail
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