GO:0004654
JSON
polyribonucleotide nucleotidyltransferase activity
Molecular Function
Definition (GO:0004654 GONUTS page)
Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
nucleoside diphosphate:polynucleotidyl transferase activity | related |
polynucleotide phosphorylase activity | related |
polyribonucleotide phosphorylase activity | related |
polyribonucleotide:phosphate nucleotidyltransferase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q4H4F3 | 1397 | BTRD_NIACI | GO:0016779 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17226887 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.7.8 | |
InterPro | IPR012162 | Polyribonucleotide nucleotidyltransferase |
InterPro | IPR014069 | Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase |
MetaCyc | 2.7.7.8-RXN | |
RHEA | 22096 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:43474 | hydrogenphosphate |
has_participant | CHEBI | CHEBI:57930 | nucleoside 5'-diphosphate(3-) |
has_participant | CHEBI | CHEBI:140395 | poly(nucleoside 5'-monophosphate) polyanion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004654 based on ALL annotations
The top 100 of 349 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
polyribonucleotide nucleotidyltransferase activity
|
4,036.92 | 100.00 | 48,289 | 48,289 |
3'-5'-RNA exonuclease activity
|
1,046.72 | 25.87 | 47,898 | 184,729 |
mRNA catabolic process
|
882.23 | 21.83 | 48,059 | 219,909 |
RNA catabolic process
|
434.75 | 10.67 | 44,320 | 411,540 |
mitochondrial mRNA catabolic process
|
3,781.99 | 6.70 | 3,249 | 3,468 |
mitochondrial RNA 3'-end processing
|
1,601.46 | 6.10 | 3,249 | 8,190 |
RNA processing
|
162.78 | 4.01 | 42,421 | 1,052,040 |
nucleotidyltransferase activity
|
89.71 | 2.22 | 43,134 | 1,940,928 |
magnesium ion binding
|
46.71 | 1.15 | 36,480 | 3,152,949 |
chloroplast stroma
|
54.70 | 0.85 | 1,082 | 79,851 |
Totals | 501451 | 108243449 |
No co-occurrence statistics for GO:0004654 based on MANUAL annotations
The top 61 of 61 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
polyribonucleotide nucleotidyltransferase activity
|
7,735.32 | 100.00 | 167 | 167 |
mitochondrial mRNA catabolic process
|
7,178.83 | 72.88 | 129 | 139 |
mitochondrial RNA 3'-end processing
|
3,538.50 | 40.31 | 129 | 282 |
3'-5'-RNA exonuclease activity
|
848.69 | 10.96 | 166 | 1,513 |
mitochondrial RNA catabolic process
|
2,667.35 | 5.38 | 10 | 29 |
mitochondrial mRNA polyadenylation
|
2,784.72 | 4.92 | 9 | 25 |
RNA import into mitochondrion
|
7,735.32 | 4.79 | 8 | 8 |
RNA catabolic process
|
407.12 | 4.61 | 45 | 855 |
positive regulation of mitochondrial RNA catabolic process
|
3,256.98 | 4.49 | 8 | 19 |
rRNA import into mitochondrion
|
2,812.85 | 4.42 | 8 | 22 |
Totals | 1192 | 670069 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Deleted | DEFINITION | Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. |
2023-09-23 | Added | DEFINITION | Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate. |
2020-10-08 | Added | SYNONYM | polyribonucleotide:phosphate nucleotidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | nucleoside diphosphate:polynucleotidyl transferase activity |
2020-10-08 | Deleted | SYNONYM | polyribonucleotide phosphorylase activity |
2020-10-08 | Deleted | SYNONYM | polyribonucleotide:phosphate nucleotidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | polynucleotide phosphorylase activity |
2020-10-08 | Added | SYNONYM | nucleoside diphosphate:polynucleotidyl transferase activity |
2020-10-08 | Added | SYNONYM | polyribonucleotide phosphorylase activity |
2020-10-08 | Added | SYNONYM | polynucleotide phosphorylase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | polyribonucleotide nucleotidyltransferase activity |
2002-02-06 | Updated | TERM | polyribonucleotide nucleotidyltransferase |
2001-04-03 | Updated | TERM | polyribonucleotide nucleotidyltransferase |
2001-03-30 | Added | TERM | polyribonucleotide nucleotidyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-23 | Deleted | DEFINITION | Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. |
2023-09-23 | Added | DEFINITION | Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate. |
2020-10-08 | Added | SYNONYM | polyribonucleotide:phosphate nucleotidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | nucleoside diphosphate:polynucleotidyl transferase activity |
2020-10-08 | Deleted | SYNONYM | polyribonucleotide phosphorylase activity |
2020-10-08 | Deleted | SYNONYM | polyribonucleotide:phosphate nucleotidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | polynucleotide phosphorylase activity |
2020-10-08 | Added | SYNONYM | nucleoside diphosphate:polynucleotidyl transferase activity |
2020-10-08 | Added | SYNONYM | polyribonucleotide phosphorylase activity |
2020-10-08 | Added | SYNONYM | polynucleotide phosphorylase activity |
2016-08-21 | Added | DEFINITION | Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. |
2016-08-21 | Deleted | DEFINITION | Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1). |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1). |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1). |
2007-11-08 | Added | SYNONYM | polyribonucleotide:phosphate nucleotidyltransferase activity |
2007-11-08 | Added | SYNONYM | polyribonucleotide phosphorylase activity |
2007-11-08 | Added | SYNONYM | nucleoside diphosphate:polynucleotidyl transferase activity |
2007-09-06 | Added | SYNONYM | polynucleotide phosphorylase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016779 (nucleotidyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:22096 |
2003-10-27 | Added | XREF | MetaCyc:2.7.7.8-RXN |
2001-03-30 | Added | XREF | EC:2.7.7.8 |
Timestamp | Action | Category | Detail |
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