This term is obsolete.

GO:0004654 JSON

polyribonucleotide nucleotidyltransferase activity

Molecular Function

Definition (GO:0004654 GONUTS page)

Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.

49,214 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
polyribonucleotide:phosphate nucleotidyltransferase activity related
nucleoside diphosphate:polynucleotidyl transferase activity related
polynucleotide phosphorylase activity related
polyribonucleotide phosphorylase activity related

Ancestor Chart

Ancestor chart for GO:0004654
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q4H4F3 1397 BTRD_NIACI GO:0016779 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17226887
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.7.7.8
InterPro IPR012162 Polyribonucleotide nucleotidyltransferase
InterPro IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase
MetaCyc 2.7.7.8-RXN
RHEA 22096

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:43474 hydrogenphosphate
has_participant CHEBI CHEBI:140395 poly(nucleoside 5'-monophosphate) polyanion
has_participant CHEBI CHEBI:57930 nucleoside 5'-diphosphate(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004654 based on ALL annotations
The top 100 of 352 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polyribonucleotide nucleotidyltransferase activity
4,042.33 100.00 49,020 49,020
3'-5'-RNA exonuclease activity
1,037.36 25.61 48,632 189,506
mRNA catabolic process
901.79 22.29 48,791 218,708
RNA catabolic process
435.47 10.66 44,805 415,912
mitochondrial mRNA catabolic process
3,804.22 7.11 3,499 3,718
mitochondrial RNA 3'-end processing
1,634.97 6.46 3,499 8,651
RNA processing
163.38 4.02 43,038 1,064,849
nucleotidyltransferase activity
91.55 2.26 43,777 1,933,012
magnesium ion binding
46.41 1.14 36,834 3,208,148
chloroplast stroma
57.19 0.91 1,213 85,743
Totals 507695 106843457
No co-occurrence statistics for GO:0004654 based on MANUAL annotations
The top 61 of 61 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polyribonucleotide nucleotidyltransferase activity
7,713.30 100.00 183 183
mitochondrial mRNA catabolic process
7,215.66 75.13 145 155
mitochondrial RNA 3'-end processing
3,619.51 41.79 145 309
3'-5'-RNA exonuclease activity
894.72 11.59 182 1,569
mitochondrial RNA catabolic process
2,337.36 4.85 10 33
mitochondrial mRNA polyadenylation
3,305.70 4.62 9 21
RNA import into mitochondrion
7,713.30 4.37 8 8
RNA catabolic process
369.65 4.18 45 939
positive regulation of mitochondrial RNA catabolic process
3,247.70 4.12 8 19
rRNA import into mitochondrion
2,804.83 4.06 8 22
Totals 1287 726888

Change Log

Timestamp Action Category Detail
2023-09-23 Added DEFINITION Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
2023-09-23 Deleted DEFINITION Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
2020-10-08 Added SYNONYM polyribonucleotide:phosphate nucleotidyltransferase activity
2020-10-08 Deleted SYNONYM polyribonucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM nucleoside diphosphate:polynucleotidyl transferase activity
2020-10-08 Added SYNONYM polynucleotide phosphorylase activity
2020-10-08 Added SYNONYM polyribonucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM polynucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM polyribonucleotide:phosphate nucleotidyltransferase activity
2020-10-08 Added SYNONYM nucleoside diphosphate:polynucleotidyl transferase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM polyribonucleotide nucleotidyltransferase activity
2002-02-06 Updated TERM polyribonucleotide nucleotidyltransferase
2001-04-03 Updated TERM polyribonucleotide nucleotidyltransferase
2001-03-30 Added TERM polyribonucleotide nucleotidyltransferase
Timestamp Action Category Detail
2023-09-23 Added DEFINITION Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
2023-09-23 Deleted DEFINITION Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
2020-10-08 Added SYNONYM polyribonucleotide:phosphate nucleotidyltransferase activity
2020-10-08 Deleted SYNONYM polyribonucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM nucleoside diphosphate:polynucleotidyl transferase activity
2020-10-08 Added SYNONYM polynucleotide phosphorylase activity
2020-10-08 Added SYNONYM polyribonucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM polynucleotide phosphorylase activity
2020-10-08 Deleted SYNONYM polyribonucleotide:phosphate nucleotidyltransferase activity
2020-10-08 Added SYNONYM nucleoside diphosphate:polynucleotidyl transferase activity
2016-08-21 Added DEFINITION Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
2016-08-21 Deleted DEFINITION Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1).
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1).
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1).
2007-11-08 Added SYNONYM polyribonucleotide:phosphate nucleotidyltransferase activity
2007-11-08 Added SYNONYM nucleoside diphosphate:polynucleotidyl transferase activity
2007-11-08 Added SYNONYM polyribonucleotide phosphorylase activity
2007-09-06 Added SYNONYM polynucleotide phosphorylase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1).
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016779 (nucleotidyltransferase activity)
Timestamp Action Category Detail
2020-06-22 Added XREF RHEA:22096
2003-10-27 Added XREF MetaCyc:2.7.7.8-RXN
2001-03-30 Added XREF EC:2.7.7.8
Timestamp Action Category Detail
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