GO:0005501
JSON
retinoid binding
Molecular Function
Definition (GO:0005501 GONUTS page)
Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005501
Child Term | Relationship to GO:0005501 |
---|---|
retinal binding
|
is_a |
retinol binding
|
is_a |
retinoic acid binding
|
is_a |
3,4-didehydroretinal binding
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P05943 | 10116 | S10AA_RAT | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P60903 | 9606 | S10AA_HUMAN | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR002449 | Retinol binding protein/Purpurin |
InterPro | IPR032956 | Retinol-binding protein 3 |
Reactome | R-HSA-2454113 | |
Reactome | R-HSA-2464809 | |
Reactome | R-HSA-2465934 | |
Reactome | R-HSA-2465938 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:26537 | retinoid |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005501 based on ALL annotations
The top 100 of 174 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
retinoid binding
|
66,532.01 | 100.00 | 2,930 | 2,930 |
retinol transport
|
24,750.99 | 31.09 | 1,917 | 5,153 |
retinol transmembrane transporter activity
|
24,750.99 | 31.09 | 1,917 | 5,153 |
retinal binding
|
23,437.41 | 22.40 | 1,116 | 3,168 |
retinol binding
|
13,135.61 | 19.16 | 2,538 | 12,855 |
response to retinoic acid
|
2,633.83 | 2.23 | 142 | 3,587 |
prostaglandin-D synthase activity
|
10,970.70 | 1.91 | 62 | 376 |
negative regulation of male germ cell proliferation
|
14,878.47 | 1.70 | 53 | 237 |
regulation of circadian sleep/wake cycle, sleep
|
6,201.25 | 1.68 | 59 | 633 |
maintenance of gastrointestinal epithelium
|
2,203.36 | 1.64 | 92 | 2,778 |
Totals | 16690 | 5986830 |
No co-occurrence statistics for GO:0005501 based on MANUAL annotations
The top 79 of 79 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
retinoid binding
|
35,883.31 | 100.00 | 36 | 36 |
prostaglandin-D synthase activity
|
18,659.32 | 27.08 | 13 | 25 |
regulation of circadian sleep/wake cycle, sleep
|
4,172.48 | 8.93 | 10 | 86 |
all-trans retinal binding
|
6,407.73 | 8.47 | 5 | 28 |
rod photoreceptor disc membrane
|
35,883.31 | 8.33 | 3 | 3 |
N-retinylidene-phosphatidylethanolamine flippase activity
|
21,529.98 | 7.89 | 3 | 5 |
prostaglandin biosynthetic process
|
2,727.97 | 6.70 | 13 | 171 |
rough endoplasmic reticulum
|
2,468.16 | 6.13 | 13 | 189 |
negative regulation of male germ cell proliferation
|
7,974.07 | 4.65 | 2 | 9 |
retinol transmembrane transporter activity
|
7,974.07 | 4.65 | 2 | 9 |
Totals | 300 | 963861 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2465934 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2454113 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2465938 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2465934 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2464809 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2464809 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2454113 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2465938 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | retinoid binding |
2003-03-19 | Updated | TERM | retinoid binding activity |
2002-02-06 | Updated | TERM | retinoid binding |
2001-04-03 | Updated | TERM | retinoid binding |
2001-03-30 | Added | TERM | retinoid binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2008-05-13 | Added | DEFINITION | Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2004-10-08 | Updated | DEFINITION | Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
2003-03-26 | Added | DEFINITION | Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0019840 (isoprenoid binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-2465934 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2454113 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2465938 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2465934 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2464809 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2464809 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2454113 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2465938 |
2018-12-11 | Added | XREF | reactome:R-HSA-2464809 |
2018-12-11 | Added | XREF | reactome:R-HSA-2465938 |
2018-12-11 | Added | XREF | reactome:R-HSA-2465934 |
2018-12-11 | Added | XREF | reactome:R-HSA-2454113 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-01 | Deleted | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2015-12-09 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
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