This term is obsolete.

GO:0005501 JSON

retinoid binding

Molecular Function

Definition (GO:0005501 GONUTS page)

Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.

21,227 annotations

Ancestor Chart

Ancestor chart for GO:0005501
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005501

Child Term Relationship to
GO:0005501
retinal binding
is_a
retinol binding
is_a
retinoic acid binding
is_a
3,4-didehydroretinal binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P05943 10116 S10AA_RAT GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P60903 9606 S10AA_HUMAN GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394

Cross-references

Database ID Description
InterPro IPR002449 Retinol binding protein/Purpurin
InterPro IPR032956 Retinol-binding protein 3
Reactome R-HSA-2454113
Reactome R-HSA-2464809
Reactome R-HSA-2465934
Reactome R-HSA-2465938

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:26537 retinoid

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005501 based on ALL annotations
The top 100 of 174 co-occurring terms
Co-occurring Term PR S% #Together #Compared
retinoid binding
66,532.01 100.00 2,930 2,930
retinol transport
24,750.99 31.09 1,917 5,153
retinol transmembrane transporter activity
24,750.99 31.09 1,917 5,153
retinal binding
23,437.41 22.40 1,116 3,168
retinol binding
13,135.61 19.16 2,538 12,855
response to retinoic acid
2,633.83 2.23 142 3,587
prostaglandin-D synthase activity
10,970.70 1.91 62 376
negative regulation of male germ cell proliferation
14,878.47 1.70 53 237
regulation of circadian sleep/wake cycle, sleep
6,201.25 1.68 59 633
maintenance of gastrointestinal epithelium
2,203.36 1.64 92 2,778
Totals 16690 5986830
No co-occurrence statistics for GO:0005501 based on MANUAL annotations
The top 79 of 79 co-occurring terms
Co-occurring Term PR S% #Together #Compared
retinoid binding
35,883.31 100.00 36 36
prostaglandin-D synthase activity
18,659.32 27.08 13 25
regulation of circadian sleep/wake cycle, sleep
4,172.48 8.93 10 86
all-trans retinal binding
6,407.73 8.47 5 28
rod photoreceptor disc membrane
35,883.31 8.33 3 3
N-retinylidene-phosphatidylethanolamine flippase activity
21,529.98 7.89 3 5
prostaglandin biosynthetic process
2,727.97 6.70 13 171
rough endoplasmic reticulum
2,468.16 6.13 13 189
negative regulation of male germ cell proliferation
7,974.07 4.65 2 9
retinol transmembrane transporter activity
7,974.07 4.65 2 9
Totals 300 963861

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2019-04-01 Deleted XREF reactome:R-HSA-2465934
2019-04-01 Deleted XREF reactome:R-HSA-2454113
2019-04-01 Added XREF Reactome:R-HSA-2465938
2019-04-01 Added XREF Reactome:R-HSA-2465934
2019-04-01 Deleted XREF reactome:R-HSA-2464809
2019-04-01 Added XREF Reactome:R-HSA-2464809
2019-04-01 Added XREF Reactome:R-HSA-2454113
2019-04-01 Deleted XREF reactome:R-HSA-2465938
Timestamp Action Category Detail
2003-06-10 Updated TERM retinoid binding
2003-03-19 Updated TERM retinoid binding activity
2002-02-06 Updated TERM retinoid binding
2001-04-03 Updated TERM retinoid binding
2001-03-30 Added TERM retinoid binding
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2009-07-03 Deleted DEFINITION Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2008-05-13 Added DEFINITION Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2008-05-12 Deleted DEFINITION Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2004-10-08 Updated DEFINITION Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2003-03-26 Added DEFINITION Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0019840 (isoprenoid binding)
Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-2465934
2019-04-01 Deleted XREF reactome:R-HSA-2454113
2019-04-01 Added XREF Reactome:R-HSA-2465938
2019-04-01 Added XREF Reactome:R-HSA-2465934
2019-04-01 Deleted XREF reactome:R-HSA-2464809
2019-04-01 Added XREF Reactome:R-HSA-2464809
2019-04-01 Added XREF Reactome:R-HSA-2454113
2019-04-01 Deleted XREF reactome:R-HSA-2465938
2018-12-11 Added XREF reactome:R-HSA-2464809
2018-12-11 Added XREF reactome:R-HSA-2465938
2018-12-11 Added XREF reactome:R-HSA-2465934
2018-12-11 Added XREF reactome:R-HSA-2454113
Timestamp Action Category Detail
2018-02-01 Deleted CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2015-12-09 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
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