GO:0005543
JSON
phospholipid binding
Molecular Function
Definition (GO:0005543 GONUTS page)
Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.
Ancestor Chart
Ancestor chart for GO:0005543
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005543
Child Term | Relationship to GO:0005543 |
---|---|
calcium-dependent phospholipid binding
|
is_a |
ceramide 1-phosphate binding
|
is_a |
phosphatidylcholine binding
|
is_a |
phosphatidylglycerol binding
|
is_a |
phosphatidic acid binding
|
is_a |
phosphatidylethanolamine binding
|
is_a |
phosphatidylinositol binding
|
is_a |
phosphatidylserine binding
|
is_a |
lysophosphatidic acid binding
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5YC76 | 10116 | A0A8I5YC76_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AFU4 | 10116 | A0A8I6AFU4_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A9K3Y6U2 | 10116 | A0A9K3Y6U2_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7UJ12 | 10116 | A7UJ12_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O15537 | 9606 | XLRS1_HUMAN | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:21196491 | |
NOT-qualified manual | protein | P05943 | 10116 | S10AA_RAT | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P50232 | 10116 | SYT4_RAT | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9830048 | |
NOT-qualified manual | protein | P60903 | 9606 | S10AA_HUMAN | GO:0008289 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394 | |
NOT-qualified manual | protein | Q8VY07 | 3702 | EPN1_ARATH | GO:0005543 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17277094 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001605 | Pleckstrin homology domain, spectrin-type |
InterPro | IPR011417 | AP180 N-terminal homology (ANTH) domain |
InterPro | IPR024774 | Pleckstrin homology domain, Mcp5-type |
InterPro | IPR037302 | Protein Unc-13, C2B domain |
InterPro | IPR037303 | Synaptotagmin-like protein 4/5, C2A domain |
InterPro | IPR037470 | Protein IVY1 |
InterPro | IPR037773 | RASA2, PH domain |
InterPro | IPR037777 | RASA4, PH domain |
InterPro | IPR044518 | ADP-ribosylation factor GTPase-activating protein AGD11/12/13 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:16247 | phospholipid |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005543 based on ALL annotations
The top 100 of 3,144 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phospholipid binding
|
1,352.79 | 100.00 | 144,101 | 144,101 |
lipid-A-disaccharide synthase activity
|
1,152.03 | 18.24 | 27,154 | 31,886 |
clathrin binding
|
314.20 | 9.19 | 19,029 | 81,929 |
clathrin vesicle coat
|
721.87 | 8.59 | 13,375 | 25,065 |
endocytosis
|
117.69 | 5.85 | 21,869 | 251,377 |
lipid A biosynthetic process
|
104.88 | 5.81 | 27,154 | 350,239 |
clathrin-coated vesicle
|
234.97 | 4.97 | 9,371 | 53,951 |
phospholipid transporter activity
|
180.07 | 4.88 | 10,302 | 77,396 |
calcium-dependent phospholipase A2 activity
|
538.08 | 4.81 | 7,481 | 18,808 |
arachidonate secretion
|
410.38 | 4.64 | 7,485 | 24,674 |
Totals | 773424 | 7306034 |
No co-occurrence statistics for GO:0005543 based on MANUAL annotations
The top 100 of 2,359 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phospholipid binding
|
607.33 | 100.00 | 2,127 | 2,127 |
clathrin vesicle coat
|
313.80 | 16.60 | 418 | 809 |
clathrin binding
|
244.20 | 15.35 | 423 | 1,052 |
phosphatidylglycerol metabolic process
|
532.85 | 8.64 | 186 | 212 |
phosphatidylcholine metabolic process
|
402.07 | 8.54 | 190 | 287 |
calcium-dependent phospholipase A2 activity
|
326.49 | 8.13 | 186 | 346 |
nuclear pore central transport channel
|
197.69 | 7.67 | 194 | 596 |
phosphatidylinositol-3,4-bisphosphate binding
|
257.66 | 7.67 | 182 | 429 |
endocytosis
|
57.04 | 6.83 | 426 | 4,536 |
endosome
|
51.55 | 6.78 | 537 | 6,327 |
Totals | 10846 | 213583 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2021-05-24 | Added | DEFINITION | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. |
2020-11-03 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2017-03-19 | Added | RELATION | has part GO:0120014 (phospholipid transfer activity) |
2016-11-28 | Added | RELATION | is a GO:0043168 (anion binding) |
2016-06-22 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2013-05-09 | Added | RELATION | is a GO:0043168 (anion binding) |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2008-05-13 | Added | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | phospholipid binding |
2003-03-19 | Updated | TERM | phospholipid binding activity |
2002-02-06 | Updated | TERM | phospholipid binding |
2001-04-03 | Updated | TERM | phospholipid binding |
2001-03-30 | Added | TERM | phospholipid binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2021-05-24 | Added | DEFINITION | Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2008-05-13 | Added | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2003-03-26 | Updated | DEFINITION | Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2017-03-19 | Added | RELATION | has part GO:0120014 (phospholipid transfer activity) |
2016-11-28 | Added | RELATION | is a GO:0043168 (anion binding) |
2016-06-22 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2013-05-09 | Added | RELATION | is a GO:0043168 (anion binding) |
2008-04-01 | Updated | RELATION | is a GO:0008289 (lipid binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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