This term is obsolete.

GO:0005543 JSON

phospholipid binding

Molecular Function

Definition (GO:0005543 GONUTS page)

Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.

774,657 annotations

Ancestor Chart

Ancestor chart for GO:0005543
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005543

Child Term Relationship to
GO:0005543
calcium-dependent phospholipid binding
is_a
ceramide 1-phosphate binding
is_a
phosphatidylcholine binding
is_a
phosphatidylglycerol binding
is_a
phosphatidic acid binding
is_a
phosphatidylethanolamine binding
is_a
phosphatidylinositol binding
is_a
phosphatidylserine binding
is_a
lysophosphatidic acid binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5YC76 10116 A0A8I5YC76_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AFU4 10116 A0A8I6AFU4_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A9K3Y6U2 10116 A0A9K3Y6U2_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7UJ12 10116 A7UJ12_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O15537 9606 XLRS1_HUMAN GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:21196491
NOT-qualified manual protein P05943 10116 S10AA_RAT GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P50232 10116 SYT4_RAT GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9830048
NOT-qualified manual protein P60903 9606 S10AA_HUMAN GO:0008289 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23861394
NOT-qualified manual protein Q8VY07 3702 EPN1_ARATH GO:0005543 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17277094

Cross-references

Database ID Description
InterPro IPR001605 Pleckstrin homology domain, spectrin-type
InterPro IPR011417 AP180 N-terminal homology (ANTH) domain
InterPro IPR024774 Pleckstrin homology domain, Mcp5-type
InterPro IPR037302 Protein Unc-13, C2B domain
InterPro IPR037303 Synaptotagmin-like protein 4/5, C2A domain
InterPro IPR037470 Protein IVY1
InterPro IPR037773 RASA2, PH domain
InterPro IPR037777 RASA4, PH domain
InterPro IPR044518 ADP-ribosylation factor GTPase-activating protein AGD11/12/13

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:16247 phospholipid

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005543 based on ALL annotations
The top 100 of 3,144 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phospholipid binding
1,352.79 100.00 144,101 144,101
lipid-A-disaccharide synthase activity
1,152.03 18.24 27,154 31,886
clathrin binding
314.20 9.19 19,029 81,929
clathrin vesicle coat
721.87 8.59 13,375 25,065
endocytosis
117.69 5.85 21,869 251,377
lipid A biosynthetic process
104.88 5.81 27,154 350,239
clathrin-coated vesicle
234.97 4.97 9,371 53,951
phospholipid transporter activity
180.07 4.88 10,302 77,396
calcium-dependent phospholipase A2 activity
538.08 4.81 7,481 18,808
arachidonate secretion
410.38 4.64 7,485 24,674
Totals 773424 7306034
No co-occurrence statistics for GO:0005543 based on MANUAL annotations
The top 100 of 2,359 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phospholipid binding
607.33 100.00 2,127 2,127
clathrin vesicle coat
313.80 16.60 418 809
clathrin binding
244.20 15.35 423 1,052
phosphatidylglycerol metabolic process
532.85 8.64 186 212
phosphatidylcholine metabolic process
402.07 8.54 190 287
calcium-dependent phospholipase A2 activity
326.49 8.13 186 346
nuclear pore central transport channel
197.69 7.67 194 596
phosphatidylinositol-3,4-bisphosphate binding
257.66 7.67 182 429
endocytosis
57.04 6.83 426 4,536
endosome
51.55 6.78 537 6,327
Totals 10846 213583

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2021-05-24 Added DEFINITION Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.
2020-11-03 Deleted RELATION is a GO:0043168 (anion binding)
2017-03-19 Added RELATION has part GO:0120014 (phospholipid transfer activity)
2016-11-28 Added RELATION is a GO:0043168 (anion binding)
2016-06-22 Deleted RELATION is a GO:0043168 (anion binding)
2013-05-09 Added RELATION is a GO:0043168 (anion binding)
2009-07-03 Deleted DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2008-05-13 Added DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
Timestamp Action Category Detail
2003-06-10 Updated TERM phospholipid binding
2003-03-19 Updated TERM phospholipid binding activity
2002-02-06 Updated TERM phospholipid binding
2001-04-03 Updated TERM phospholipid binding
2001-03-30 Added TERM phospholipid binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2021-05-24 Added DEFINITION Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.
2009-07-03 Deleted DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2008-05-13 Added DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2008-05-12 Deleted DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2003-03-26 Updated DEFINITION Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
Timestamp Action Category Detail
2020-11-03 Deleted RELATION is a GO:0043168 (anion binding)
2017-03-19 Added RELATION has part GO:0120014 (phospholipid transfer activity)
2016-11-28 Added RELATION is a GO:0043168 (anion binding)
2016-06-22 Deleted RELATION is a GO:0043168 (anion binding)
2013-05-09 Added RELATION is a GO:0043168 (anion binding)
2008-04-01 Updated RELATION is a GO:0008289 (lipid binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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