This term is obsolete.

GO:0005643 JSON

nuclear pore

Cellular Component

Definition (GO:0005643 GONUTS page)

A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.

Secondary IDs

GO:0005644

295,302 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
nuclear pore membrane protein narrow
NPC exact
nuclear pore complex exact
nucleopore exact

Ancestor Chart

Ancestor chart for GO:0005643
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005643

Child Term Relationship to
GO:0005643
GO:0044611
nuclear pore inner ring
part_of
GO:0044612
nuclear pore linkers
part_of
GO:0017056
structural constituent of nuclear pore
occurs_in
GO:1990875
nucleoplasmic side of nuclear pore
part_of
GO:1990876
cytoplasmic side of nuclear pore
part_of
GO:0031080
nuclear pore outer ring
part_of
GO:0070762
nuclear pore transmembrane ring
part_of
GO:0044615
nuclear pore nuclear basket
part_of
GO:0044613
nuclear pore central transport channel
part_of
GO:0044614
nuclear pore cytoplasmic filaments
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005643 nuclear pore Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR004870 Nucleoporin, Nup155-like
InterPro IPR007230 Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain
InterPro IPR007231 Nucleoporin interacting component Nup93/Nic96
InterPro IPR007252 Nuclear pore protein 84/107
InterPro IPR012476 mRNA export factor GLE1-like
InterPro IPR015007 Nuclear pore complex, NUP2/50/61
InterPro IPR018783 Transcription factor, enhancer of yellow 2
InterPro IPR021827 Nucleoporin Nup186/Nup192/Nup205
InterPro IPR024864 Nucleoporin Nup54/Nup57/Nup44
InterPro IPR024882 Nucleoporin p58/p45/NUP49

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0005646 obsolete importin consider GO:0005643
GO:0005647 obsolete importin, alpha-subunit consider GO:0005643
GO:0005648 obsolete importin, beta-subunit consider GO:0005643
GO:0005649 obsolete transportin consider GO:0005643
GO:0005650 obsolete importin, alpha-subunit transport factor consider GO:0005643
GO:0005651 obsolete exportin consider GO:0005643

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005643 based on ALL annotations
The top 100 of 2,037 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0005643
nuclear pore
1,459.62 100.00 135,758 135,758
GO:0017056
structural constituent of nuclear pore
1,369.24 54.04 76,083 81,105
GO:0051028
mRNA transport
608.82 28.39 63,895 153,185
GO:0006606
protein import into nucleus
503.28 23.55 57,887 167,885
GO:0006913
nucleocytoplasmic transport
697.64 20.78 36,490 76,345
GO:0006405
RNA export from nucleus
1,153.01 17.59 25,053 31,715
GO:0031080
nuclear pore outer ring
1,104.88 14.72 20,974 27,708
GO:0006406
mRNA export from nucleus
460.90 12.65 23,665 74,945
GO:0008139
nuclear localization sequence binding
1,297.02 12.37 17,063 19,202
GO:0006999
nuclear pore organization
1,290.47 11.26 15,518 17,552
Totals 1016200 21913606
No co-occurrence statistics for GO:0005643 based on MANUAL annotations
The top 100 of 848 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0005643
nuclear pore
757.26 100.00 1,864 1,864
GO:0017056
structural constituent of nuclear pore
295.40 22.48 646 1,656
GO:0006405
RNA export from nucleus
252.42 12.11 298 894
GO:0006611
protein export from nucleus
230.35 10.39 254 835
GO:0005049
nuclear export signal receptor activity
252.42 10.17 238 714
GO:0006913
nucleocytoplasmic transport
305.88 8.66 185 458
GO:0006606
protein import into nucleus
87.91 8.49 448 3,859
GO:0000972
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
335.88 7.97 165 372
GO:0006406
mRNA export from nucleus
110.98 7.89 272 1,856
GO:0008139
nuclear localization sequence binding
103.36 7.22 248 1,817
Totals 8801 153606

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pir 438

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2020-11-24 Added DEFINITION A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2020-11-24 Deleted DEFINITION Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2020-11-03 Deleted RELATION is a GO:0032991 (protein-containing complex)
2020-11-03 Added RELATION is a GO:0140513 (nuclear protein-containing complex)
2019-09-12 Deleted RELATION is a GO:0044428 (obsolete nuclear part)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2016-07-29 Added RELATION is a GO:0043234 (protein complex)
2015-08-21 Deleted RELATION is a GO:0046930 (pore complex)
Timestamp Action Category Detail
2002-02-06 Updated TERM nuclear pore
2001-04-03 Updated TERM nuclear pore
2001-03-30 Added TERM nuclear pore
Timestamp Action Category Detail
2020-11-24 Added DEFINITION A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2020-11-24 Deleted DEFINITION Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2011-08-10 Added SYNONYM nucleopore
2008-05-13 Added DEFINITION Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2008-05-12 Deleted DEFINITION Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2007-08-09 Added SYNONYM NPC
2007-08-09 Deleted SYNONYM nuclear pore complex
2007-08-09 Deleted SYNONYM nuclear pore membrane protein
2007-08-09 Added SYNONYM nuclear pore membrane protein
2007-08-09 Deleted SYNONYM NPC
2007-08-09 Added SYNONYM nuclear pore complex
2005-08-20 Deleted SYNONYM transportin
2005-08-20 Deleted SYNONYM importin, beta-subunit
2005-08-20 Deleted SYNONYM importin, alpha-subunit transport factor
2005-08-20 Deleted SYNONYM importin, alpha-subunit
2005-08-20 Deleted SYNONYM exportin
2005-08-20 Deleted SYNONYM RAN-binding protein
2005-08-20 Deleted SYNONYM importin
2005-08-10 Added SYNONYM transportin
2005-08-10 Added SYNONYM importin, beta-subunit
2005-08-10 Added SYNONYM exportin
2005-08-10 Added SYNONYM importin, alpha-subunit
2005-08-10 Added SYNONYM importin, alpha-subunit transport factor
2005-08-10 Added SYNONYM importin
2005-08-10 Added SYNONYM RAN-binding protein
2004-04-19 Added SYNONYM NPC
2004-04-19 Added SYNONYM nuclear pore membrane protein
2004-04-19 Added SYNONYM nuclear pore complex
2004-04-16 Deleted SYNONYM nuclear pore complex
2004-04-16 Deleted SYNONYM NPC
2004-04-16 Deleted SYNONYM nuclear pore membrane protein
2002-11-28 Added SYNONYM nuclear pore membrane protein
2001-08-06 Added DEFINITION Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2001-03-30 Added SYNONYM nuclear pore complex
2001-03-30 Added SYNONYM NPC
Timestamp Action Category Detail
2020-11-03 Deleted RELATION is a GO:0032991 (protein-containing complex)
2020-11-03 Added RELATION is a GO:0140513 (nuclear protein-containing complex)
2019-09-12 Deleted RELATION is a GO:0044428 (obsolete nuclear part)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2016-07-29 Added RELATION is a GO:0043234 (protein complex)
2015-08-21 Deleted RELATION is a GO:0046930 (pore complex)
2009-12-10 Deleted RELATION is a GO:0043234 (protein complex)
2008-10-21 Added RELATION is a GO:0044428 (obsolete nuclear part)
2008-10-02 Deleted RELATION is a GO:0044453 (obsolete nuclear membrane part)
2008-10-02 Added RELATION part of GO:0005635 (nuclear envelope)
2008-04-01 Updated RELATION is a GO:0046930 (pore complex)
2008-04-01 Updated RELATION is a GO:0044453 (obsolete nuclear membrane part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao220861693
2009-02-05 Added XREF Wikipedia:Nuclear_pore
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2013-04-18 Updated SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_pir
2002-11-28 Added SECONDARY GO:0005644 (nuclear pore membrane protein)
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