GO:0005643
JSON
nuclear pore
Cellular Component
Definition (GO:0005643 GONUTS page)
A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
Secondary IDs
GO:0005644
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
nucleopore | exact |
nuclear pore membrane protein | narrow |
nuclear pore complex | exact |
NPC | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005643
Child Term | Relationship to GO:0005643 |
---|---|
nuclear pore outer ring
|
part_of |
nuclear pore central transport channel
|
part_of |
nuclear pore linkers
|
part_of |
nuclear pore inner ring
|
part_of |
nuclear pore transmembrane ring
|
part_of |
cytoplasmic side of nuclear pore
|
part_of |
nuclear pore cytoplasmic filaments
|
part_of |
nucleoplasmic side of nuclear pore
|
part_of |
nuclear pore nuclear basket
|
part_of |
structural constituent of nuclear pore
|
occurs_in |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0005643 | nuclear pore | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004870 | Nucleoporin, Nup155-like |
InterPro | IPR007230 | Nuclear pore complex protein Nup98-Nup96-like, autopeptidase S59 domain |
InterPro | IPR007231 | Nucleoporin interacting component Nup93/Nic96 |
InterPro | IPR007252 | Nuclear pore protein 84/107 |
InterPro | IPR012476 | mRNA export factor GLE1-like |
InterPro | IPR015007 | Nuclear pore complex, NUP2/50/61 |
InterPro | IPR018783 | Transcription factor, enhancer of yellow 2 |
InterPro | IPR021827 | Nucleoporin Nup186/Nup192/Nup205 |
InterPro | IPR024864 | Nucleoporin Nup54/Nup57/Nup44 |
InterPro | IPR024882 | Nucleoporin p58/p45/NUP49 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0005646 | obsolete importin | consider GO:0005643 |
GO:0005647 | obsolete importin, alpha-subunit | consider GO:0005643 |
GO:0005648 | obsolete importin, beta-subunit | consider GO:0005643 |
GO:0005649 | obsolete transportin | consider GO:0005643 |
GO:0005650 | obsolete importin, alpha-subunit transport factor | consider GO:0005643 |
GO:0005651 | obsolete exportin | consider GO:0005643 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005643 based on ALL annotations
The top 100 of 2,045 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nuclear pore
|
1,474.42 | 100.00 | 132,214 | 132,214 |
structural constituent of nuclear pore
|
1,384.90 | 53.94 | 73,888 | 78,664 |
mRNA transport
|
593.78 | 27.10 | 59,907 | 148,756 |
protein import into nucleus
|
509.50 | 23.49 | 55,945 | 161,896 |
nucleocytoplasmic transport
|
710.85 | 20.97 | 35,780 | 74,214 |
RNA export from nucleus
|
1,168.37 | 17.48 | 24,223 | 30,568 |
nuclear pore outer ring
|
1,115.84 | 14.56 | 20,202 | 26,694 |
mRNA export from nucleus
|
469.94 | 12.67 | 22,984 | 72,111 |
nuclear localization sequence binding
|
1,312.24 | 12.27 | 16,466 | 18,501 |
nuclear membrane
|
404.30 | 11.75 | 22,554 | 82,250 |
Totals | 979347 | 21452487 |
No co-occurrence statistics for GO:0005643 based on MANUAL annotations
The top 100 of 854 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nuclear pore
|
692.28 | 100.00 | 1,866 | 1,866 |
structural constituent of nuclear pore
|
273.46 | 21.59 | 602 | 1,524 |
protein export from nucleus
|
268.48 | 12.13 | 280 | 722 |
RNA export from nucleus
|
229.05 | 11.10 | 267 | 807 |
nuclear export signal receptor activity
|
242.53 | 9.42 | 213 | 608 |
nucleocytoplasmic transport
|
282.63 | 8.38 | 178 | 436 |
protein import into nucleus
|
79.58 | 8.16 | 409 | 3,558 |
mRNA export from nucleus
|
101.27 | 7.52 | 250 | 1,709 |
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
|
311.73 | 7.50 | 154 | 342 |
nuclear localization sequence binding
|
92.61 | 6.74 | 223 | 1,667 |
Totals | 8687 | 146105 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pir | 439 |
Change Log
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- Term
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2020-11-24 | Added | DEFINITION | A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2020-11-24 | Deleted | DEFINITION | Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2020-11-03 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044428 (obsolete nuclear part) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2016-07-29 | Added | RELATION | is a GO:0043234 (protein complex) |
2015-08-21 | Deleted | RELATION | is a GO:0046930 (pore complex) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | nuclear pore |
2001-04-03 | Updated | TERM | nuclear pore |
2001-03-30 | Added | TERM | nuclear pore |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-24 | Added | DEFINITION | A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2020-11-24 | Deleted | DEFINITION | Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2011-08-10 | Added | SYNONYM | nucleopore |
2008-05-13 | Added | DEFINITION | Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2008-05-12 | Deleted | DEFINITION | Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2007-08-09 | Deleted | SYNONYM | NPC |
2007-08-09 | Added | SYNONYM | nuclear pore membrane protein |
2007-08-09 | Added | SYNONYM | nuclear pore complex |
2007-08-09 | Added | SYNONYM | NPC |
2007-08-09 | Deleted | SYNONYM | nuclear pore complex |
2007-08-09 | Deleted | SYNONYM | nuclear pore membrane protein |
2005-08-20 | Deleted | SYNONYM | RAN-binding protein |
2005-08-20 | Deleted | SYNONYM | exportin |
2005-08-20 | Deleted | SYNONYM | transportin |
2005-08-20 | Deleted | SYNONYM | importin, beta-subunit |
2005-08-20 | Deleted | SYNONYM | importin, alpha-subunit transport factor |
2005-08-20 | Deleted | SYNONYM | importin |
2005-08-20 | Deleted | SYNONYM | importin, alpha-subunit |
2005-08-10 | Added | SYNONYM | transportin |
2005-08-10 | Added | SYNONYM | RAN-binding protein |
2005-08-10 | Added | SYNONYM | exportin |
2005-08-10 | Added | SYNONYM | importin |
2005-08-10 | Added | SYNONYM | importin, alpha-subunit |
2005-08-10 | Added | SYNONYM | importin, alpha-subunit transport factor |
2005-08-10 | Added | SYNONYM | importin, beta-subunit |
2004-04-19 | Added | SYNONYM | NPC |
2004-04-19 | Added | SYNONYM | nuclear pore complex |
2004-04-19 | Added | SYNONYM | nuclear pore membrane protein |
2004-04-16 | Deleted | SYNONYM | NPC |
2004-04-16 | Deleted | SYNONYM | nuclear pore complex |
2004-04-16 | Deleted | SYNONYM | nuclear pore membrane protein |
2002-11-28 | Added | SYNONYM | nuclear pore membrane protein |
2001-08-06 | Added | DEFINITION | Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
2001-03-30 | Added | SYNONYM | NPC |
2001-03-30 | Added | SYNONYM | nuclear pore complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044428 (obsolete nuclear part) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2016-07-29 | Added | RELATION | is a GO:0043234 (protein complex) |
2015-08-21 | Deleted | RELATION | is a GO:0046930 (pore complex) |
2009-12-10 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-10-21 | Added | RELATION | is a GO:0044428 (obsolete nuclear part) |
2008-10-02 | Deleted | RELATION | is a GO:0044453 (obsolete nuclear membrane part) |
2008-10-02 | Added | RELATION | part of GO:0005635 (nuclear envelope) |
2008-04-01 | Updated | RELATION | is a GO:0046930 (pore complex) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044453 (obsolete nuclear membrane part) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-04 | Added | XREF | NIF_Subcellular:sao220861693 |
2009-02-05 | Added | XREF | Wikipedia:Nuclear_pore |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2013-04-18 | Updated | SUBSET | goslim_pir |
2008-06-09 | Added | SUBSET | goslim_pir |
2002-11-28 | Added | SECONDARY | GO:0005644 (nuclear pore membrane protein) |
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