This term is obsolete.

GO:0005769 JSON

early endosome

Cellular Component

Definition (GO:0005769 GONUTS page)

A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. PMID:19696797

238,936 annotations

Ancestor Chart

Ancestor chart for GO:0005769
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005769

Child Term Relationship to
GO:0005769
early endosome lumen
part_of
early endosome membrane
part_of
postsynaptic early endosome
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005769 early endosome Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0031410 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR028290 WASH1
NIF_Subcellular nlx_subcell_20090701
UniProtKB-SubCell SL-0094 Early endosome

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005769 based on ALL annotations
The top 100 of 5,024 co-occurring terms
Co-occurring Term PR S% #Together #Compared
early endosome
1,391.66 100.00 142,387 142,387
recycling endosome
559.36 14.17 25,570 63,617
late endosome
359.97 12.63 28,172 108,916
endosome
168.52 10.31 58,255 481,072
endocytic recycling
415.90 9.09 16,441 55,014
phosphatidylinositol binding
171.86 7.81 24,930 201,874
voltage-gated chloride channel activity
464.63 7.09 11,760 35,224
early endosome to late endosome transport
814.78 6.12 9,107 15,555
endosome organization
353.31 6.10 10,582 41,682
endosome to lysosome transport
426.24 5.74 9,396 30,678
Totals 766550 10451871
No co-occurrence statistics for GO:0005769 based on MANUAL annotations
The top 100 of 4,074 co-occurring terms
Co-occurring Term PR S% #Together #Compared
early endosome
420.98 100.00 3,353 3,353
recycling endosome
166.09 14.96 651 1,650
endocytic recycling
129.45 10.96 488 1,587
late endosome
96.31 10.22 523 2,286
endosome organization
124.31 7.89 326 1,104
receptor recycling
366.07 7.67 260 299
retrograde transport, endosome to Golgi
54.29 6.45 383 2,970
endocytic vesicle
82.67 6.24 281 1,431
phosphatidylinositol binding
66.71 5.55 264 1,666
trans-Golgi network
34.29 5.12 407 4,996
Totals 16490 246424

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2014-10-05 Added XREF NIF_Subcellular:nlx_subcell_20090701
2011-02-25 Added DEFINITION A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2011-02-25 Deleted DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2008-05-13 Added DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2008-05-12 Deleted DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2008-04-01 Updated RELATION is a GO:0005768 (endosome)
2004-04-17 Updated DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2004-04-15 Added DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered
2002-02-06 Updated TERM early endosome
Timestamp Action Category Detail
2002-02-06 Updated TERM early endosome
2001-04-03 Updated TERM early endosome
2001-03-30 Added TERM early endosome
Timestamp Action Category Detail
2011-02-25 Added DEFINITION A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2011-02-25 Deleted DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2008-05-13 Added DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2008-05-12 Deleted DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2004-04-17 Updated DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2004-04-15 Added DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005768 (endosome)
Timestamp Action Category Detail
2014-10-05 Added XREF NIF_Subcellular:nlx_subcell_20090701
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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