GO:0005769
JSON
early endosome
Cellular Component
Definition (GO:0005769 GONUTS page)
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. PMID:19696797
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005769
Child Term | Relationship to GO:0005769 |
---|---|
early endosome lumen
|
part_of |
early endosome membrane
|
part_of |
postsynaptic early endosome
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0005769 | early endosome | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 5270 | A0A0D1E8X3_MYCMD | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0031410 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR028290 | WASH1 |
NIF_Subcellular | nlx_subcell_20090701 | |
UniProtKB-SubCell | SL-0094 | Early endosome |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005769 based on ALL annotations
The top 100 of 5,024 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
early endosome
|
1,391.66 | 100.00 | 142,387 | 142,387 |
recycling endosome
|
559.36 | 14.17 | 25,570 | 63,617 |
late endosome
|
359.97 | 12.63 | 28,172 | 108,916 |
endosome
|
168.52 | 10.31 | 58,255 | 481,072 |
endocytic recycling
|
415.90 | 9.09 | 16,441 | 55,014 |
phosphatidylinositol binding
|
171.86 | 7.81 | 24,930 | 201,874 |
voltage-gated chloride channel activity
|
464.63 | 7.09 | 11,760 | 35,224 |
early endosome to late endosome transport
|
814.78 | 6.12 | 9,107 | 15,555 |
endosome organization
|
353.31 | 6.10 | 10,582 | 41,682 |
endosome to lysosome transport
|
426.24 | 5.74 | 9,396 | 30,678 |
Totals | 766550 | 10451871 |
No co-occurrence statistics for GO:0005769 based on MANUAL annotations
The top 100 of 4,074 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
early endosome
|
420.98 | 100.00 | 3,353 | 3,353 |
recycling endosome
|
166.09 | 14.96 | 651 | 1,650 |
endocytic recycling
|
129.45 | 10.96 | 488 | 1,587 |
late endosome
|
96.31 | 10.22 | 523 | 2,286 |
endosome organization
|
124.31 | 7.89 | 326 | 1,104 |
receptor recycling
|
366.07 | 7.67 | 260 | 299 |
retrograde transport, endosome to Golgi
|
54.29 | 6.45 | 383 | 2,970 |
endocytic vesicle
|
82.67 | 6.24 | 281 | 1,431 |
phosphatidylinositol binding
|
66.71 | 5.55 | 264 | 1,666 |
trans-Golgi network
|
34.29 | 5.12 | 407 | 4,996 |
Totals | 16490 | 246424 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2014-10-05 | Added | XREF | NIF_Subcellular:nlx_subcell_20090701 |
2011-02-25 | Added | DEFINITION | A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
2011-02-25 | Deleted | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2008-05-13 | Added | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2008-05-12 | Deleted | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2008-04-01 | Updated | RELATION | is a GO:0005768 (endosome) |
2004-04-17 | Updated | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2004-04-15 | Added | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered |
2002-02-06 | Updated | TERM | early endosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | early endosome |
2001-04-03 | Updated | TERM | early endosome |
2001-03-30 | Added | TERM | early endosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-02-25 | Added | DEFINITION | A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
2011-02-25 | Deleted | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2008-05-13 | Added | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2008-05-12 | Deleted | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2004-04-17 | Updated | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered. |
2004-04-15 | Added | DEFINITION | Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0005768 (endosome) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-10-05 | Added | XREF | NIF_Subcellular:nlx_subcell_20090701 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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