This term is obsolete.

GO:0005771 JSON

multivesicular body

Cellular Component

Definition (GO:0005771 GONUTS page)

A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. PMID:11566881 PMID:16533950

39,692 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
MVE exact
multivesicular endosome exact
MVB exact

Ancestor Chart

Ancestor chart for GO:0005771
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005771

Child Term Relationship to
GO:0005771
multivesicular body, internal vesicle
part_of
multivesicular body lumen
part_of
multivesicular body membrane
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005771 multivesicular body Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0031410 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
NIF_Subcellular sao2045955158
UniProtKB-SubCell SL-0174 Multivesicular body

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005771 based on ALL annotations
The top 100 of 1,756 co-occurring terms
Co-occurring Term PR S% #Together #Compared
multivesicular body
7,166.54 100.00 27,650 27,650
late endosome to vacuole transport via multivesicular body sorting pathway
5,536.25 66.53 22,878 29,615
ESCRT III complex
6,875.20 50.37 14,230 14,833
vesicle budding from membrane
4,769.69 49.60 18,268 27,448
vacuolar transport
2,055.45 25.31 18,876 65,813
endosome membrane
408.88 5.04 8,331 146,019
intracellular transport
514.45 4.89 3,679 51,250
cytoplasmic side of plasma membrane
343.79 4.40 9,647 201,098
endosome
211.84 2.88 14,220 481,072
kinetochore microtubule
1,169.15 2.50 794 4,867
Totals 190733 6205208
No co-occurrence statistics for GO:0005771 based on MANUAL annotations
The top 100 of 1,193 co-occurring terms
Co-occurring Term PR S% #Together #Compared
multivesicular body
899.07 100.00 1,570 1,570
ESCRT III complex
878.25 66.14 1,055 1,080
endosome transport via multivesicular body sorting pathway
821.96 36.72 597 653
late endosome to vacuole transport via multivesicular body sorting pathway
544.11 36.24 745 1,231
late endosome to vacuole transport
557.09 31.20 606 978
vesicle budding from membrane
403.86 26.58 619 1,378
protein transport
286.31 21.00 599 1,881
cytoplasmic side of plasma membrane
208.61 12.59 339 1,461
surfactant homeostasis
282.92 2.70 45 143
positive regulation of phagocytosis
83.63 2.36 48 516
Totals 7791 76129

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2016-04-17 Deleted RELATION is a GO:0005768 (endosome)
2016-04-17 Added RELATION is a GO:0005770 (late endosome)
2015-08-30 Deleted RELATION is a GO:0005770 (late endosome)
2015-08-30 Added RELATION is a GO:0005768 (endosome)
2015-08-30 Deleted DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2015-08-30 Added DEFINITION A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2010-02-04 Added XREF NIF_Subcellular:sao2045955158
2008-05-13 Added DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2008-05-12 Deleted DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
Timestamp Action Category Detail
2002-02-06 Updated TERM multivesicular body
2001-04-03 Updated TERM multivesicular body
2001-03-30 Added TERM multivesicular body
Timestamp Action Category Detail
2015-08-30 Deleted DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2015-08-30 Added DEFINITION A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2008-05-13 Added DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2008-05-12 Deleted DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2007-08-09 Deleted SYNONYM MVE
2007-08-09 Added SYNONYM MVB
2007-08-09 Added SYNONYM MVE
2007-08-09 Added SYNONYM multivesicular endosome
2007-08-09 Deleted SYNONYM MVB
2007-08-09 Deleted SYNONYM multivesicular endosome
2006-11-29 Added SYNONYM multivesicular endosome
2006-11-29 Added SYNONYM MVE
2004-04-19 Added SYNONYM MVB
2004-04-16 Deleted SYNONYM MVB
2004-03-16 Updated DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
2004-03-11 Added DEFINITION A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm
2004-03-11 Added SYNONYM MVB
Timestamp Action Category Detail
2016-04-17 Deleted RELATION is a GO:0005768 (endosome)
2016-04-17 Added RELATION is a GO:0005770 (late endosome)
2015-08-30 Deleted RELATION is a GO:0005770 (late endosome)
2015-08-30 Added RELATION is a GO:0005768 (endosome)
2008-04-01 Updated RELATION is a GO:0005770 (late endosome)
Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao2045955158
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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