GO:0005771
JSON
multivesicular body
Cellular Component
Definition (GO:0005771 GONUTS page)
A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. PMID:11566881 PMID:16533950
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
MVE | exact |
multivesicular endosome | exact |
MVB | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0005771
Child Term | Relationship to GO:0005771 |
---|---|
multivesicular body, internal vesicle
|
part_of |
multivesicular body lumen
|
part_of |
multivesicular body membrane
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0005771 | multivesicular body | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 5270 | A0A0D1E8X3_MYCMD | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0031410 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
NIF_Subcellular | sao2045955158 | |
UniProtKB-SubCell | SL-0174 | Multivesicular body |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005771 based on ALL annotations
The top 100 of 1,756 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
multivesicular body
|
7,166.54 | 100.00 | 27,650 | 27,650 |
late endosome to vacuole transport via multivesicular body sorting pathway
|
5,536.25 | 66.53 | 22,878 | 29,615 |
ESCRT III complex
|
6,875.20 | 50.37 | 14,230 | 14,833 |
vesicle budding from membrane
|
4,769.69 | 49.60 | 18,268 | 27,448 |
vacuolar transport
|
2,055.45 | 25.31 | 18,876 | 65,813 |
endosome membrane
|
408.88 | 5.04 | 8,331 | 146,019 |
intracellular transport
|
514.45 | 4.89 | 3,679 | 51,250 |
cytoplasmic side of plasma membrane
|
343.79 | 4.40 | 9,647 | 201,098 |
endosome
|
211.84 | 2.88 | 14,220 | 481,072 |
kinetochore microtubule
|
1,169.15 | 2.50 | 794 | 4,867 |
Totals | 190733 | 6205208 |
No co-occurrence statistics for GO:0005771 based on MANUAL annotations
The top 100 of 1,193 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
multivesicular body
|
899.07 | 100.00 | 1,570 | 1,570 |
ESCRT III complex
|
878.25 | 66.14 | 1,055 | 1,080 |
endosome transport via multivesicular body sorting pathway
|
821.96 | 36.72 | 597 | 653 |
late endosome to vacuole transport via multivesicular body sorting pathway
|
544.11 | 36.24 | 745 | 1,231 |
late endosome to vacuole transport
|
557.09 | 31.20 | 606 | 978 |
vesicle budding from membrane
|
403.86 | 26.58 | 619 | 1,378 |
protein transport
|
286.31 | 21.00 | 599 | 1,881 |
cytoplasmic side of plasma membrane
|
208.61 | 12.59 | 339 | 1,461 |
surfactant homeostasis
|
282.92 | 2.70 | 45 | 143 |
positive regulation of phagocytosis
|
83.63 | 2.36 | 48 | 516 |
Totals | 7791 | 76129 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2016-04-17 | Deleted | RELATION | is a GO:0005768 (endosome) |
2016-04-17 | Added | RELATION | is a GO:0005770 (late endosome) |
2015-08-30 | Deleted | RELATION | is a GO:0005770 (late endosome) |
2015-08-30 | Added | RELATION | is a GO:0005768 (endosome) |
2015-08-30 | Deleted | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2015-08-30 | Added | DEFINITION | A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2010-02-04 | Added | XREF | NIF_Subcellular:sao2045955158 |
2008-05-13 | Added | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2008-05-12 | Deleted | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | multivesicular body |
2001-04-03 | Updated | TERM | multivesicular body |
2001-03-30 | Added | TERM | multivesicular body |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-08-30 | Deleted | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2015-08-30 | Added | DEFINITION | A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2008-05-13 | Added | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2008-05-12 | Deleted | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2007-08-09 | Deleted | SYNONYM | MVE |
2007-08-09 | Added | SYNONYM | MVB |
2007-08-09 | Added | SYNONYM | MVE |
2007-08-09 | Added | SYNONYM | multivesicular endosome |
2007-08-09 | Deleted | SYNONYM | MVB |
2007-08-09 | Deleted | SYNONYM | multivesicular endosome |
2006-11-29 | Added | SYNONYM | multivesicular endosome |
2006-11-29 | Added | SYNONYM | MVE |
2004-04-19 | Added | SYNONYM | MVB |
2004-04-16 | Deleted | SYNONYM | MVB |
2004-03-16 | Updated | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. |
2004-03-11 | Added | DEFINITION | A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm |
2004-03-11 | Added | SYNONYM | MVB |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-04-17 | Deleted | RELATION | is a GO:0005768 (endosome) |
2016-04-17 | Added | RELATION | is a GO:0005770 (late endosome) |
2015-08-30 | Deleted | RELATION | is a GO:0005770 (late endosome) |
2015-08-30 | Added | RELATION | is a GO:0005768 (endosome) |
2008-04-01 | Updated | RELATION | is a GO:0005770 (late endosome) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-04 | Added | XREF | NIF_Subcellular:sao2045955158 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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