This term is obsolete.

GO:0005774 JSON

vacuolar membrane

Cellular Component

Definition (GO:0005774 GONUTS page)

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

555,950 annotations

Ancestor Chart

Ancestor chart for GO:0005774
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0005774

Child Term Relationship to
GO:0005774
high-affinity iron exporter complex
part_of
Ragulator complex
part_of
autophagosome membrane
is_a
contractile vacuolar membrane
is_a
plant-type vacuole membrane
is_a
vacuolar proton-transporting V-type ATPase complex
part_of
vacuolar proton-transporting V-type ATPase, V0 domain
part_of
lytic vacuole membrane
is_a
vacuolar HOPS complex
part_of
PAS complex
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005774 vacuolar membrane Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 237631 A0A0D1E8X3_USTMA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
UniProtKB-SubCell SL-0271 Vacuole membrane

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0000306 obsolete extrinsic component of vacuolar membrane consider GO:0005774
GO:0031166 obsolete integral component of vacuolar membrane replaced_by GO:0005774
GO:0031310 obsolete intrinsic component of vacuolar membrane replaced_by GO:0005774

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0005774 based on ALL annotations
The top 100 of 2,190 co-occurring terms
Co-occurring Term PR S% #Together #Compared
vacuolar membrane
1,355.58 100.00 143,805 143,805
vacuole
712.50 29.69 58,316 110,950
fungal-type vacuole membrane
353.07 11.59 24,849 95,405
calcium:proton antiporter activity
900.62 9.44 14,251 21,450
L-amino acid transmembrane transporter activity
258.36 8.17 18,004 94,466
L-alpha-amino acid transmembrane transport
195.97 7.17 17,890 123,752
soluble NSF attachment protein activity
1,308.89 6.19 8,916 9,234
intracellular calcium ion homeostasis
161.27 5.63 13,900 116,839
proton-transporting V-type ATPase, V0 domain
316.53 5.50 9,642 41,293
syntaxin binding
243.15 4.83 8,916 49,708
Totals 744415 13094497
No co-occurrence statistics for GO:0005774 based on MANUAL annotations
The top 100 of 714 co-occurring terms
Co-occurring Term PR S% #Together #Compared
vacuolar membrane
768.47 100.00 1,681 1,681
L-amino acid transmembrane transporter activity
199.56 13.79 382 1,471
amino acid transmembrane transport
88.62 8.55 417 3,616
L-cystine transport
457.72 6.21 109 183
L-cystine transmembrane transporter activity
448.62 6.14 108 185
cellular response to amino acid starvation
101.53 4.55 109 825
positive regulation of TORC1 signaling
90.46 4.14 101 858
proton-transporting V-type ATPase complex
219.56 4.06 76 266
manganese ion transmembrane transporter activity
67.50 3.87 109 1,241
intracellular sequestering of iron ion
112.04 3.39 71 487
Totals 5373 101412

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2020-09-24 Deleted RELATION is a GO:0098805 (whole membrane)
2019-09-12 Deleted RELATION is a GO:0044437 (obsolete vacuolar part)
2017-07-11 Added RELATION part of GO:0005773 (vacuole)
2017-05-05 Deleted RELATION part of GO:0005773 (vacuole)
2017-05-01 Added RELATION part of GO:0005773 (vacuole)
2015-06-25 Deleted RELATION is a GO:0031090 (organelle membrane)
2015-05-11 Added RELATION is a GO:0098805 (whole membrane)
2014-06-05 Added RELATION is a GO:0031090 (organelle membrane)
2014-03-07 Added RELATION is a GO:0098588 (bounding membrane of organelle)
Timestamp Action Category Detail
2002-02-06 Updated TERM vacuolar membrane
2001-04-03 Updated TERM vacuolar membrane
2001-03-30 Added TERM vacuolar membrane
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
2008-05-12 Deleted DEFINITION The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
2003-03-19 Deleted SYNONYM extrinsic vacuolar membrane protein
2002-11-27 Added DEFINITION The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
2002-01-19 Added SYNONYM extrinsic vacuolar membrane protein
Timestamp Action Category Detail
2020-09-24 Deleted RELATION is a GO:0098805 (whole membrane)
2019-09-12 Deleted RELATION is a GO:0044437 (obsolete vacuolar part)
2017-07-11 Added RELATION part of GO:0005773 (vacuole)
2017-05-05 Deleted RELATION part of GO:0005773 (vacuole)
2017-05-01 Added RELATION part of GO:0005773 (vacuole)
2015-06-25 Deleted RELATION is a GO:0031090 (organelle membrane)
2015-05-11 Added RELATION is a GO:0098805 (whole membrane)
2014-06-05 Added RELATION is a GO:0031090 (organelle membrane)
2014-03-07 Added RELATION is a GO:0098588 (bounding membrane of organelle)
2014-03-07 Deleted RELATION is a GO:0031090 (organelle membrane)
2008-04-01 Updated RELATION is a GO:0044437 (obsolete vacuolar part)
2008-04-01 Updated RELATION is a GO:0031090 (organelle membrane)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2002-02-21 Deleted SECONDARY GO:0000306 (obsolete extrinsic component of vacuolar membrane)
2002-01-19 Added SECONDARY GO:0000306 (obsolete extrinsic component of vacuolar membrane)
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