GO:0005960
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glycine cleavage complex
Cellular Component
Definition (GO:0005960 GONUTS page)
A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.
Secondary IDs
GO:0005961, GO:0070015
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
glycine dehydrogenase complex (decarboxylating) | related |
glycine synthase complex | exact |
glycine cleavage system | exact |
glycine dehydrogenase (decarboxylating) complex | exact |
glycine decarboxylase complex | exact |
Ancestor Chart
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR002930 | Glycine cleavage system H-protein |
InterPro | IPR006223 | Glycine cleavage system T protein |
InterPro | IPR017453 | Glycine cleavage system H-protein, subgroup |
Wikipedia | Glycine_decarboxylase_complex |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0005960 based on ALL annotations
The top 100 of 461 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycine cleavage complex
|
1,544.21 | 100.00 | 128,321 | 128,321 |
glycine decarboxylation via glycine cleavage system
|
1,423.58 | 81.90 | 112,934 | 122,504 |
glycine catabolic process
|
1,376.41 | 54.16 | 74,408 | 83,479 |
glycine binding
|
1,332.64 | 32.20 | 43,550 | 50,464 |
glycine dehydrogenase (decarboxylating) activity
|
1,161.22 | 30.66 | 43,772 | 58,209 |
aminomethyltransferase activity
|
1,466.94 | 28.49 | 37,116 | 39,071 |
transaminase activity
|
47.29 | 2.85 | 36,794 | 1,201,488 |
pyridoxal phosphate binding
|
38.43 | 2.37 | 43,815 | 1,760,728 |
cytosol
|
10.62 | 0.69 | 96,200 | 13,989,509 |
chloroplast envelope
|
59.68 | 0.61 | 914 | 23,648 |
Totals | 767137 | 92242537 |
No co-occurrence statistics for GO:0005960 based on MANUAL annotations
The top 67 of 67 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycine cleavage complex
|
3,610.06 | 100.00 | 391 | 391 |
glycine decarboxylation via glycine cleavage system
|
3,510.78 | 96.77 | 389 | 400 |
glycine dehydrogenase (decarboxylating) activity
|
3,522.54 | 40.76 | 161 | 165 |
glycine binding
|
2,285.40 | 32.57 | 157 | 248 |
pyridoxal phosphate binding
|
238.74 | 6.02 | 157 | 2,374 |
glycine catabolic process
|
1,805.03 | 3.69 | 15 | 30 |
aminomethyltransferase activity
|
1,263.52 | 1.73 | 7 | 20 |
one-carbon metabolic process
|
252.70 | 1.45 | 7 | 100 |
protein lipoylation
|
416.55 | 0.72 | 3 | 26 |
mitochondrion
|
26.10 | 0.72 | 354 | 48,955 |
Totals | 1789 | 794094 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pir | 438 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-07 | Deleted | RELATION | part of GO:0005737 (cytoplasm) |
2024-09-07 | Deleted | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2019-09-20 | Added | RELATION | is a GO:1990204 (oxidoreductase complex) |
2019-09-20 | Deleted | RELATION | is a GO:1902494 (catalytic complex) |
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2019-08-30 | Deleted | RELATION | is a GO:1990204 (oxidoreductase complex) |
2019-08-30 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2015-06-18 | Added | RELATION | capable of GO:0004375 (glycine dehydrogenase (decarboxylating) activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-05-24 | Updated | TERM | glycine cleavage complex |
2002-06-12 | Updated | TERM | glycine cleavage system complex |
2002-02-06 | Updated | TERM | glycine cleavage system |
2001-04-03 | Updated | TERM | glycine cleavage system |
2001-03-30 | Added | TERM | glycine cleavage system |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-25 | Added | SYNONYM | glycine dehydrogenase (decarboxylating) complex |
2009-02-25 | Added | SYNONYM | glycine decarboxylase complex |
2009-02-25 | Added | DEFINITION | A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T. |
2009-02-25 | Deleted | DEFINITION | A multienzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase. |
2008-05-13 | Added | DEFINITION | A multienzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase. |
2008-05-12 | Deleted | DEFINITION | A multienzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase. |
2008-02-22 | Added | SYNONYM | glycine dehydrogenase complex (decarboxylating) |
2007-08-09 | Added | SYNONYM | glycine cleavage system |
2007-08-09 | Deleted | SYNONYM | glycine synthase complex |
2007-08-09 | Deleted | SYNONYM | glycine cleavage system |
2007-08-09 | Added | SYNONYM | glycine synthase complex |
2004-04-19 | Added | SYNONYM | glycine cleavage system |
2004-04-19 | Added | SYNONYM | glycine synthase complex |
2004-04-16 | Deleted | SYNONYM | glycine synthase complex |
2004-04-16 | Deleted | SYNONYM | glycine cleavage system |
2003-05-24 | Added | SYNONYM | glycine synthase complex |
2003-05-24 | Added | SYNONYM | glycine cleavage system |
2003-05-24 | Deleted | SYNONYM | glycine synthase |
2003-04-17 | Updated | DEFINITION | A multienzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase. |
2003-04-09 | Updated | DEFINITION | A multi-enzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase. |
2002-11-27 | Added | DEFINITION | An enzyme complex composed of aminomethyltransferase and glycine dehydrogenase (decarboxylating). It catalyzes the cleavage of glycine, forming dihydrolipoylprotein, methylenetetrahydrofolate and ammonia. |
2001-03-30 | Added | SYNONYM | glycine synthase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-07 | Deleted | RELATION | part of GO:0005737 (cytoplasm) |
2019-09-20 | Added | RELATION | is a GO:1990204 (oxidoreductase complex) |
2019-09-20 | Deleted | RELATION | is a GO:1902494 (catalytic complex) |
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2019-08-30 | Deleted | RELATION | is a GO:1990204 (oxidoreductase complex) |
2019-08-30 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2015-06-18 | Added | RELATION | capable of GO:0004375 (glycine dehydrogenase (decarboxylating) activity) |
2013-10-24 | Added | RELATION | is a GO:1990204 (oxidoreductase complex) |
2013-10-24 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-08 | Added | XREF | Wikipedia:Glycine_decarboxylase_complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-07 | Deleted | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2013-04-18 | Updated | SUBSET | goslim_pir |
2009-02-25 | Added | SECONDARY | GO:0070015 (glycine decarboxylase complex) |
2008-06-09 | Added | SUBSET | goslim_pir |
2008-02-22 | Added | SECONDARY | GO:0005961 (glycine dehydrogenase complex (decarboxylating)) |
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