GO:0006103
JSON
2-oxoglutarate metabolic process
Biological Process
Definition (GO:0006103 GONUTS page)
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
2-ketoglutarate metabolic process | exact |
2-ketoglutarate metabolism | exact |
alpha-oxoglutarate metabolism | exact |
alpha-oxoglutarate metabolic process | exact |
alpha-ketoglutarate metabolism | exact |
alpha-ketoglutarate metabolic process | exact |
2-oxoglutarate metabolism | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006103
Child Term | Relationship to GO:0006103 |
---|---|
mixed acid fermentation
|
is_a |
L-histidine catabolic process to 2-oxoglutarate
|
is_a |
proline catabolic process to 2-oxoglutarate
|
is_a |
L-arabinose catabolic process to 2-oxoglutarate
|
is_a |
acetyl-CoA assimilation pathway
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR020373 | Alpha-ketoglutarate dehydrogenase component 4/YMR-31 |
Reactome | R-HSA-2978092 | |
Reactome | R-HSA-880009 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input_or_output | CHEBI | CHEBI:16810 | 2-oxoglutarate(2-) |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0006100 | obsolete tricarboxylic acid cycle intermediate metabolic process | consider GO:0006103 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006103 based on ALL annotations
The top 100 of 591 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
2-oxoglutarate metabolic process
|
2,187.99 | 100.00 | 89,095 | 89,095 |
dihydrolipoyl dehydrogenase activity
|
2,126.05 | 93.32 | 85,464 | 87,954 |
pyruvate metabolic process
|
704.56 | 31.77 | 85,464 | 265,404 |
oxoglutarate dehydrogenase complex
|
258.26 | 5.48 | 8,278 | 70,132 |
NAD(P)+ transhydrogenase (Si-specific) activity
|
2,137.27 | 5.43 | 4,846 | 4,961 |
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
|
315.80 | 5.29 | 6,871 | 47,605 |
flavin adenine dinucleotide binding
|
112.61 | 5.14 | 85,463 | 1,660,475 |
nucleotide binding
|
81.15 | 3.67 | 68,305 | 1,841,736 |
NADP metabolic process
|
378.15 | 3.02 | 3,140 | 18,168 |
oxoglutarate dehydrogenase (succinyl-transferring) activity
|
120.54 | 1.79 | 2,309 | 41,912 |
Totals | 569369 | 63312635 |
No co-occurrence statistics for GO:0006103 based on MANUAL annotations
The top 100 of 335 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
2-oxoglutarate metabolic process
|
3,018.22 | 100.00 | 428 | 428 |
dihydrolipoyl dehydrogenase activity
|
2,855.08 | 63.06 | 280 | 296 |
oxoglutarate dehydrogenase complex
|
1,096.00 | 29.41 | 260 | 716 |
pyruvate metabolic process
|
818.90 | 23.73 | 280 | 1,032 |
glutamate metabolic process
|
909.60 | 8.30 | 44 | 146 |
flavin adenine dinucleotide binding
|
242.05 | 7.69 | 279 | 3,479 |
aspartate metabolic process
|
1,411.12 | 7.68 | 36 | 77 |
L-aspartate:2-oxoglutarate aminotransferase activity
|
288.56 | 4.76 | 37 | 387 |
oxoglutarate dehydrogenase (succinyl-transferring) activity
|
301.82 | 3.51 | 22 | 220 |
aspartate biosynthetic process
|
545.46 | 3.02 | 15 | 83 |
Totals | 2498 | 75582 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-2978092 |
2024-12-05 | Added | XREF | Reactome:R-HSA-880009 |
2019-07-06 | Deleted | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2009-07-03 | Deleted | RELATION | is a GO:0042180 (ketone metabolic process) |
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2008-04-01 | Updated | RELATION | is a GO:0042180 (ketone metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0043648 (dicarboxylic acid metabolic process) |
2007-08-09 | Deleted | SYNONYM | 2-ketoglutarate metabolic process |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-01-15 | Updated | TERM | 2-oxoglutarate metabolic process |
2002-10-03 | Updated | TERM | 2-oxoglutarate metabolism |
2002-02-06 | Updated | TERM | 2-oxo-glutarate metabolism |
2001-10-15 | Updated | TERM | 2-oxo-glutarate metabolism |
2001-04-03 | Updated | TERM | 2-oxoglutarate metabolism |
2001-03-30 | Added | TERM | 2-oxoglutarate metabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2007-08-09 | Deleted | SYNONYM | 2-ketoglutarate metabolic process |
2007-08-09 | Deleted | SYNONYM | alpha-ketoglutarate metabolic process |
2007-08-09 | Deleted | SYNONYM | alpha-oxoglutarate metabolic process |
2007-08-09 | Deleted | SYNONYM | alpha-oxoglutarate metabolism |
2007-08-09 | Deleted | SYNONYM | 2-oxoglutarate metabolism |
2007-08-09 | Added | SYNONYM | alpha-oxoglutarate metabolic process |
2007-08-09 | Added | SYNONYM | 2-ketoglutarate metabolic process |
2007-08-09 | Added | SYNONYM | 2-ketoglutarate metabolism |
2007-08-09 | Added | SYNONYM | 2-oxoglutarate metabolism |
2007-08-09 | Deleted | SYNONYM | alpha-ketoglutarate metabolism |
2007-08-09 | Deleted | SYNONYM | 2-ketoglutarate metabolism |
2007-08-09 | Added | SYNONYM | alpha-ketoglutarate metabolism |
2007-08-09 | Added | SYNONYM | alpha-ketoglutarate metabolic process |
2007-08-09 | Added | SYNONYM | alpha-oxoglutarate metabolism |
2007-01-29 | Added | SYNONYM | 2-oxoglutarate metabolism |
2007-01-15 | Added | SYNONYM | alpha-ketoglutarate metabolic process |
2007-01-15 | Added | SYNONYM | 2-ketoglutarate metabolic process |
2007-01-15 | Added | SYNONYM | alpha-oxoglutarate metabolic process |
2006-05-04 | Updated | DEFINITION | The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2005-07-09 | Deleted | SYNONYM | ketoglutarate metabolism |
2005-07-09 | Added | SYNONYM | 2-ketoglutarate metabolism |
2005-07-09 | Added | SYNONYM | alpha-ketoglutarate metabolism |
2005-07-09 | Added | SYNONYM | alpha-oxoglutarate metabolism |
2005-01-21 | Updated | DEFINITION | The chemical reactions involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2004-04-19 | Added | SYNONYM | ketoglutarate metabolism |
2004-04-16 | Deleted | SYNONYM | ketoglutarate metabolism |
2002-11-27 | Added | DEFINITION | The chemical reactions and physical changes involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. |
2002-10-03 | Added | SYNONYM | ketoglutarate metabolism |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-07-06 | Deleted | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2017-11-29 | Added | RELATION | is a GO:0051186 (obsolete cofactor metabolic process) |
2009-07-03 | Deleted | RELATION | is a GO:0042180 (ketone metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0042180 (ketone metabolic process) |
2008-04-01 | Updated | RELATION | is a GO:0043648 (dicarboxylic acid metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-2978092 |
2024-12-05 | Added | XREF | Reactome:R-HSA-880009 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link