GO:0006414
JSON
translational elongation
Biological Process
Definition (GO:0006414 GONUTS page)
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
Secondary IDs
GO:0006442, GO:0006455
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
translation elongation | exact |
protein synthesis elongation | broad |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006414
Child Term | Relationship to GO:0006414 |
---|---|
mitochondrial translational elongation
|
is_a |
positive regulation of translational elongation
|
positively_regulates |
translational readthrough
|
is_a |
cytoplasmic translational elongation
|
is_a |
regulation of translational elongation
|
regulates |
translational frameshifting
|
is_a |
trans-translation
|
is_a |
rescue of stalled ribosome
|
is_a |
translation elongation factor activity
|
part_of |
negative regulation of translational elongation
|
negatively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0006414 | translational elongation | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001059 | Translation elongation factor P/YeiP, central |
InterPro | IPR001326 | Translation elongation factor EF1B, beta/delta chains, conserved site |
InterPro | IPR001662 | Elongation factor 1B gamma, C-terminal |
InterPro | IPR001813 | Ribosomal protein P1/P2-like |
InterPro | IPR001816 | Translation elongation factor EFTs/EF1B |
InterPro | IPR004539 | Translation elongation factor EF1A, eukaryotic/archaeal |
InterPro | IPR004540 | Translation elongation factor EFG/EF2 |
InterPro | IPR004541 | Translation elongation factor EFTu/EF1A, bacterial/organelle |
InterPro | IPR004542 | Translation elongation factor EF1B, beta chain, archaeal |
InterPro | IPR004543 | Translation elongation factor EFG/EF2, archaeal |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0016147 | obsolete protein-synthesizing GTPase activity, elongation | consider GO:0006414 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006414 based on ALL annotations
The top 100 of 2,109 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
translational elongation
|
337.62 | 100.00 | 586,925 | 586,925 |
translation elongation factor activity
|
335.05 | 97.53 | 576,714 | 581,134 |
GTPase activity
|
65.43 | 16.45 | 305,686 | 1,577,317 |
GTP binding
|
45.09 | 12.15 | 337,000 | 2,523,530 |
ribosome disassembly
|
169.90 | 10.67 | 70,029 | 139,154 |
regulation of DNA-templated transcription elongation
|
168.89 | 9.25 | 59,842 | 119,626 |
RNA polymerase binding
|
255.33 | 9.24 | 55,871 | 73,877 |
DNA-templated transcription elongation
|
155.51 | 9.10 | 59,750 | 129,716 |
peptide biosynthetic process
|
334.95 | 7.99 | 46,943 | 47,317 |
positive regulation of translation
|
165.68 | 6.73 | 42,434 | 86,472 |
Totals | 3419603 | 195120045 |
No co-occurrence statistics for GO:0006414 based on MANUAL annotations
The top 100 of 258 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
translational elongation
|
949.25 | 100.00 | 1,487 | 1,487 |
translation elongation factor activity
|
576.74 | 50.27 | 1,107 | 1,822 |
ribosome binding
|
76.55 | 5.55 | 225 | 2,790 |
translation
|
51.09 | 4.59 | 354 | 6,577 |
ribonucleoprotein complex
|
47.66 | 3.92 | 226 | 4,501 |
guanyl-nucleotide exchange factor activity
|
42.93 | 3.75 | 268 | 5,926 |
GTPase activity
|
37.31 | 3.72 | 611 | 15,544 |
eukaryotic translation elongation factor 1 complex
|
878.93 | 1.68 | 25 | 27 |
triplet codon-amino acid adaptor activity
|
949.25 | 1.48 | 22 | 22 |
alpha-aminoacyl-tRNA binding
|
632.83 | 0.80 | 12 | 18 |
Totals | 5461 | 499923 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_yeast | 163 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-156842 |
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2023-01-08 | Added | RELATION | is a GO:0009059 (macromolecule biosynthetic process) |
2023-01-08 | Deleted | RELATION | is a GO:0034645 (obsolete cellular macromolecule biosynthetic process) |
2020-02-28 | Deleted | XREF | MIPS_funcat:12.04.02 |
2019-05-04 | Added | XREF | MIPS_funcat:12.04.02 |
2014-08-15 | Added | RELATION | has part GO:0006412 (translation) |
2013-04-18 | Updated | SUBSET | goslim_yeast |
2011-08-14 | Added | SUBSET | goslim_yeast |
2009-12-19 | Deleted | RELATION | is a GO:0034961 (cellular biopolymer biosynthetic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-08-05 | Updated | TERM | translational elongation |
2002-02-06 | Updated | TERM | protein synthesis elongation |
2001-04-03 | Updated | TERM | protein synthesis elongation |
2001-03-30 | Added | TERM | protein synthesis elongation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. |
2008-05-12 | Deleted | DEFINITION | The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. |
2007-08-09 | Deleted | SYNONYM | protein synthesis elongation |
2007-08-09 | Added | SYNONYM | translation elongation |
2007-08-09 | Added | SYNONYM | protein synthesis elongation |
2007-08-09 | Deleted | SYNONYM | translation elongation |
2007-07-11 | Deleted | SYNONYM | protein-synthesizing GTPase activity, elongation |
2005-08-19 | Added | SYNONYM | translation elongation |
2005-08-10 | Added | SYNONYM | protein-synthesizing GTPase activity, elongation |
2004-04-19 | Added | SYNONYM | protein synthesis elongation |
2004-04-16 | Deleted | SYNONYM | protein synthesis elongation |
2002-11-27 | Added | DEFINITION | The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. |
2002-08-05 | Added | SYNONYM | protein synthesis elongation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-01-08 | Added | RELATION | is a GO:0009059 (macromolecule biosynthetic process) |
2023-01-08 | Deleted | RELATION | is a GO:0034645 (obsolete cellular macromolecule biosynthetic process) |
2014-08-15 | Added | RELATION | has part GO:0006412 (translation) |
2009-12-19 | Deleted | RELATION | is a GO:0034961 (cellular biopolymer biosynthetic process) |
2009-12-19 | Added | RELATION | is a GO:0034645 (obsolete cellular macromolecule biosynthetic process) |
2008-10-02 | Deleted | RELATION | is a GO:0043284 (biopolymer biosynthetic process) |
2008-10-02 | Added | RELATION | is a GO:0034961 (cellular biopolymer biosynthetic process) |
2008-04-01 | Updated | RELATION | part of GO:0006412 (translation) |
2008-04-01 | Updated | RELATION | is a GO:0043284 (biopolymer biosynthetic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-156842 |
2020-02-28 | Deleted | XREF | MIPS_funcat:12.04.02 |
2019-05-04 | Added | XREF | MIPS_funcat:12.04.02 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2013-04-18 | Updated | SUBSET | goslim_yeast |
2011-08-14 | Added | SUBSET | goslim_yeast |
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