This term is obsolete.

GO:0006479 JSON

protein methylation

Biological Process

Definition (GO:0006479 GONUTS page)

The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.

Restrictions

This term should not be used for direct annotation.

317 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protein amino acid methylation exact

Ancestor Chart

Ancestor chart for GO:0006479
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006479

Child Term Relationship to
GO:0006479
peptidyl-histidine methylation
is_a
peptidyl-lysine methylation
is_a
peptidyl-glutamine methylation
is_a
peptidyl-cysteine methylation
is_a
C-terminal protein methylation
is_a
N-terminal protein amino acid methylation
is_a
peptidyl-arginine methylation
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q9M658 3702 MOM1_ARATH GO:0032259 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10821279

Cross-references

Database ID Description
InterPro IPR004498 Ribosomal protein L11 methyltransferase
InterPro IPR004556 Methyltransferase HemK-like
InterPro IPR007857 Protein arginine N-methyltransferase PRMT5
InterPro IPR010456 Ribosomal L11 methyltransferase, PrmA
InterPro IPR014644 Protein arginine N-methyltransferase PRMT7
InterPro IPR017127 Ribosomal protein uL3 glutamine methyltransferase
InterPro IPR038899 Methyltransferase-like protein 22
Reactome R-HSA-8876725

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006479 based on ALL annotations
The top 100 of 258 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein methylation
3,738,770.80 100.00 53 53
peptidyl-arginine methylation
505,239.34 5.88 5 37
peptidyl-lysine trimethylation
534,110.10 4.23 3 21
peptidyl-lysine dimethylation
509,832.40 4.17 3 22
peptidyl-lysine monomethylation
303,143.60 3.45 3 37
peptidyl-glutamine methylation
1,068,220.40 3.45 2 7
GATOR1 complex binding
215,698.33 2.94 3 52
peptidyl-lysine methylation
373,877.10 2.82 2 20
peptidyl-arginine omega-N-methylation
3,738,771.20 1.89 1 1
peptidyl-arginine modification
3,738,771.20 1.89 1 1
Totals 339 339540
No co-occurrence statistics for GO:0006479 based on MANUAL annotations
The top 100 of 221 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein methylation
26,632.70 100.00 53 53
negative regulation of megakaryocyte differentiation
4,438.78 6.41 5 30
peptidyl-arginine methylation
3,599.01 5.88 5 37
GATOR1 complex binding
19,974.52 5.56 3 4
lysine N-methyltransferase activity
11,414.01 5.26 3 7
regulation of megakaryocyte differentiation
3,436.48 5.00 4 31
histone H4R3 methyltransferase activity
2,663.27 4.49 4 40
cellular response to methionine
4,699.89 4.48 3 17
peptidyl-lysine trimethylation
3,804.67 4.23 3 21
peptidyl-lysine dimethylation
3,631.73 4.17 3 22
Totals 302 13706

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-8876725
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2023-06-13 Added SUBSET gocheck_do_not_annotate
2020-02-28 Deleted XREF MIPS_funcat:14.07.09
2019-05-04 Added XREF MIPS_funcat:14.07.09
2010-10-24 Added SYNONYM protein amino acid methylation
2010-10-24 Updated TERM protein methylation
2008-05-13 Added DEFINITION The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2008-05-12 Deleted DEFINITION The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
Timestamp Action Category Detail
2010-10-24 Updated TERM protein methylation
2002-02-06 Updated TERM protein amino acid methylation
2001-10-01 Updated TERM protein amino acid methylation
2001-04-03 Updated TERM protein methylation
2001-03-30 Added TERM protein methylation
Timestamp Action Category Detail
2010-10-24 Added SYNONYM protein amino acid methylation
2008-05-13 Added DEFINITION The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2008-05-12 Deleted DEFINITION The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2003-10-29 Updated DEFINITION The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
2002-11-27 Added DEFINITION The addition of a methyl group to a protein amino acid.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008213 (protein alkylation)
2008-04-01 Updated RELATION is a GO:0043414 (macromolecule methylation)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-8876725
2020-02-28 Deleted XREF MIPS_funcat:14.07.09
2019-05-04 Added XREF MIPS_funcat:14.07.09
Timestamp Action Category Detail
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2023-06-13 Added SUBSET gocheck_do_not_annotate
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