GO:0006479
JSON
protein methylation
Biological Process
Definition (GO:0006479 GONUTS page)
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
Restrictions
This term should not be used for direct annotation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
protein amino acid methylation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006479
Child Term | Relationship to GO:0006479 |
---|---|
peptidyl-histidine methylation
|
is_a |
peptidyl-lysine methylation
|
is_a |
peptidyl-glutamine methylation
|
is_a |
peptidyl-cysteine methylation
|
is_a |
C-terminal protein methylation
|
is_a |
N-terminal protein amino acid methylation
|
is_a |
peptidyl-arginine methylation
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q9M658 | 3702 | MOM1_ARATH | GO:0032259 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10821279 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004498 | Ribosomal protein L11 methyltransferase |
InterPro | IPR004556 | Methyltransferase HemK-like |
InterPro | IPR007857 | Protein arginine N-methyltransferase PRMT5 |
InterPro | IPR010456 | Ribosomal L11 methyltransferase, PrmA |
InterPro | IPR014644 | Protein arginine N-methyltransferase PRMT7 |
InterPro | IPR017127 | Ribosomal protein uL3 glutamine methyltransferase |
InterPro | IPR038899 | Methyltransferase-like protein 22 |
Reactome | R-HSA-8876725 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006479 based on ALL annotations
The top 100 of 258 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein methylation
|
3,738,770.80 | 100.00 | 53 | 53 |
peptidyl-arginine methylation
|
505,239.34 | 5.88 | 5 | 37 |
peptidyl-lysine trimethylation
|
534,110.10 | 4.23 | 3 | 21 |
peptidyl-lysine dimethylation
|
509,832.40 | 4.17 | 3 | 22 |
peptidyl-lysine monomethylation
|
303,143.60 | 3.45 | 3 | 37 |
peptidyl-glutamine methylation
|
1,068,220.40 | 3.45 | 2 | 7 |
GATOR1 complex binding
|
215,698.33 | 2.94 | 3 | 52 |
peptidyl-lysine methylation
|
373,877.10 | 2.82 | 2 | 20 |
peptidyl-arginine omega-N-methylation
|
3,738,771.20 | 1.89 | 1 | 1 |
peptidyl-arginine modification
|
3,738,771.20 | 1.89 | 1 | 1 |
Totals | 339 | 339540 |
No co-occurrence statistics for GO:0006479 based on MANUAL annotations
The top 100 of 221 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein methylation
|
26,632.70 | 100.00 | 53 | 53 |
negative regulation of megakaryocyte differentiation
|
4,438.78 | 6.41 | 5 | 30 |
peptidyl-arginine methylation
|
3,599.01 | 5.88 | 5 | 37 |
GATOR1 complex binding
|
19,974.52 | 5.56 | 3 | 4 |
lysine N-methyltransferase activity
|
11,414.01 | 5.26 | 3 | 7 |
regulation of megakaryocyte differentiation
|
3,436.48 | 5.00 | 4 | 31 |
histone H4R3 methyltransferase activity
|
2,663.27 | 4.49 | 4 | 40 |
cellular response to methionine
|
4,699.89 | 4.48 | 3 | 17 |
peptidyl-lysine trimethylation
|
3,804.67 | 4.23 | 3 | 21 |
peptidyl-lysine dimethylation
|
3,631.73 | 4.17 | 3 | 22 |
Totals | 302 | 13706 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-8876725 |
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
2020-02-28 | Deleted | XREF | MIPS_funcat:14.07.09 |
2019-05-04 | Added | XREF | MIPS_funcat:14.07.09 |
2010-10-24 | Added | SYNONYM | protein amino acid methylation |
2010-10-24 | Updated | TERM | protein methylation |
2008-05-13 | Added | DEFINITION | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
2008-05-12 | Deleted | DEFINITION | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-24 | Updated | TERM | protein methylation |
2002-02-06 | Updated | TERM | protein amino acid methylation |
2001-10-01 | Updated | TERM | protein amino acid methylation |
2001-04-03 | Updated | TERM | protein methylation |
2001-03-30 | Added | TERM | protein methylation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-24 | Added | SYNONYM | protein amino acid methylation |
2008-05-13 | Added | DEFINITION | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
2008-05-12 | Deleted | DEFINITION | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
2003-10-29 | Updated | DEFINITION | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
2002-11-27 | Added | DEFINITION | The addition of a methyl group to a protein amino acid. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008213 (protein alkylation) |
2008-04-01 | Updated | RELATION | is a GO:0043414 (macromolecule methylation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-8876725 |
2020-02-28 | Deleted | XREF | MIPS_funcat:14.07.09 |
2019-05-04 | Added | XREF | MIPS_funcat:14.07.09 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
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