This term is obsolete.

GO:0006518 JSON

peptide metabolic process

Biological Process

Definition (GO:0006518 GONUTS page)

The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.

557,759 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
peptide metabolism exact

Ancestor Chart

Ancestor chart for GO:0006518
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006518

Child Term Relationship to
GO:0006518
peptide biosynthetic process
is_a
peptide catabolic process
is_a
peptide stabilization
is_a
peptide modification
is_a
peptide antibiotic metabolic process
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1L8GRV7 8355 A0A1L8GRV7_XENLA GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8H1Z9 8355 A0A1L8H1Z9_XENLA GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2A6CPC3 54126 A0A2A6CPC3_PRIPA GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2I3SPY6 9598 A0A2I3SPY6_PANTR GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8I3NCZ1 9615 A0A8I3NCZ1_CANLF GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8M2BFA8 7955 A0A8M2BFA8_DANRE GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8V0ZA46 9031 A0A8V0ZA46_CHICK GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A2RUV9 10116 AEBP1_RAT GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A8WMX3 6238 A8WMX3_CAEBR GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7P9R8 6945 B7P9R8_IXOSC GO:0006518 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR000720 Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase
InterPro IPR010161 Peptidase M20B, tripeptide aminopeptidase
Reactome R-HSA-2980736

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:60466 peptide zwitterion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006518 based on ALL annotations
The top 100 of 589 co-occurring terms
Co-occurring Term PR S% #Together #Compared
peptide metabolic process
2,589.28 100.00 76,529 76,529
tripeptide aminopeptidase activity
2,426.67 18.05 13,983 14,920
metallocarboxypeptidase activity
267.85 6.54 11,550 111,652
protein processing involved in protein targeting to mitochondrion
574.29 5.15 4,811 21,691
peptide catabolic process
208.04 4.63 7,544 93,895
metallopeptidase activity
117.85 4.49 59,661 1,310,839
metalloendopeptidase activity
114.91 4.31 46,399 1,045,526
protein processing
122.76 3.74 11,546 243,527
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
642.22 3.66 3,147 12,688
mitochondrial intermembrane space
158.99 3.48 5,678 92,473
Totals 518249 182556248
No co-occurrence statistics for GO:0006518 based on MANUAL annotations
The top 100 of 262 co-occurring terms
Co-occurring Term PR S% #Together #Compared
peptide metabolic process
1,859.73 100.00 759 759
metallocarboxypeptidase activity
495.34 18.33 281 1,055
racemase and epimerase activity
1,579.95 12.37 96 113
protein processing
254.41 11.17 287 2,098
metalloendopeptidase activity
134.34 6.72 371 5,136
protein processing involved in protein targeting to mitochondrion
228.24 4.72 54 440
proteolysis
73.12 3.73 323 8,215
mitochondrial intermembrane space
75.03 2.76 61 1,512
creatinine metabolic process
1,505.49 2.23 17 21
amyloid-beta metabolic process
307.11 2.12 18 109
Totals 3074 155902

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pir 438

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2980736
2024-05-30 Added RELATION is a GO:0008152 (metabolic process)
2024-05-30 Deleted RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2024-03-21 Deleted RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2024-03-21 Added RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2024-03-21 Deleted RELATION is a GO:0043603 (amide metabolic process)
2013-04-18 Updated SUBSET goslim_pir
2012-11-05 Added RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2012-11-05 Deleted RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2012-11-02 Added RELATION is a GO:0043603 (amide metabolic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM peptide metabolic process
2002-02-06 Updated TERM peptide metabolism
2001-04-03 Updated TERM peptide metabolism
2001-03-30 Added TERM peptide metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2007-08-09 Deleted SYNONYM peptide metabolism
2007-08-09 Added SYNONYM peptide metabolism
2007-01-29 Added SYNONYM peptide metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2005-01-21 Updated DEFINITION The chemical reactions involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2002-11-27 Added DEFINITION The chemical reactions and physical changes involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
Timestamp Action Category Detail
2024-05-30 Added RELATION is a GO:0008152 (metabolic process)
2024-05-30 Deleted RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2024-03-21 Deleted RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2024-03-21 Added RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2024-03-21 Deleted RELATION is a GO:0043603 (amide metabolic process)
2012-11-05 Added RELATION is a GO:1901564 (obsolete organonitrogen compound metabolic process)
2012-11-05 Deleted RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2012-11-02 Added RELATION is a GO:0043603 (amide metabolic process)
2012-11-02 Added RELATION is a GO:0071704 (obsolete organic substance metabolic process)
2012-11-02 Deleted RELATION is a GO:0044237 (obsolete cellular metabolic process)
2008-04-01 Updated RELATION is a GO:0044237 (obsolete cellular metabolic process)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2980736
Timestamp Action Category Detail
2013-04-18 Updated SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_pir
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