GO:0006605
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protein targeting
Biological Process
Definition (GO:0006605 GONUTS page)
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
nascent polypeptide association | related |
protein sorting along secretory pathway | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0006605
Child Term | Relationship to GO:0006605 |
---|---|
protein targeting to Golgi apparatus
|
is_a |
protein targeting to vacuole
|
is_a |
protein targeting to chloroplast
|
is_a |
protein targeting to ER
|
is_a |
protein targeting to peroxisome
|
is_a |
protein targeting to mitochondrion
|
is_a |
regulation of protein targeting
|
regulates |
protein targeting to membrane
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02650 | 10116 | APOE_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P04639 | 10116 | APOA1_RAT | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P08226 | 10090 | APOE_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 | |
NOT-qualified manual | protein | Q00623 | 10090 | APOA1_MOUSE | GO:0008104 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000185 | Protein translocase subunit SecA |
InterPro | IPR001901 | Protein translocase complex, SecE/Sec61-gamma subunit |
InterPro | IPR002010 | Type III secretion system inner membrane R protein |
InterPro | IPR002056 | Protein import receptor MAS20 |
InterPro | IPR020937 | SecA conserved site |
InterPro | IPR022422 | Protein import receptor MAS20, metazoan |
Wikipedia | Protein_targeting |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006605 based on ALL annotations
The top 100 of 1,458 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein targeting
|
642.93 | 100.00 | 303,203 | 303,203 |
protein transport by the Sec complex
|
556.46 | 57.35 | 190,902 | 220,569 |
intracellular protein transmembrane transport
|
459.05 | 49.39 | 186,667 | 261,441 |
intracellular protein transport
|
181.81 | 23.22 | 171,263 | 605,631 |
protein-transporting ATPase activity
|
376.52 | 18.92 | 66,223 | 113,080 |
signal recognition particle binding
|
540.79 | 17.52 | 54,949 | 65,327 |
cell envelope Sec protein transport complex
|
642.89 | 17.20 | 52,139 | 52,142 |
protein import
|
246.44 | 14.40 | 56,835 | 148,276 |
SRP-dependent cotranslational protein targeting to membrane
|
245.88 | 14.02 | 54,937 | 143,652 |
protein transmembrane transporter activity
|
154.33 | 10.35 | 46,696 | 194,531 |
Totals | 2612976 | 211379922 |
No co-occurrence statistics for GO:0006605 based on MANUAL annotations
The top 100 of 894 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein targeting
|
2,942.59 | 100.00 | 439 | 439 |
Golgi to lysosome transport
|
1,307.82 | 16.03 | 88 | 198 |
mitochondrion distribution
|
1,770.76 | 14.05 | 68 | 113 |
myosin binding
|
794.20 | 12.00 | 78 | 289 |
anterograde axonal transport of mitochondrion
|
2,238.03 | 11.84 | 54 | 71 |
signal recognition particle binding
|
470.99 | 10.61 | 105 | 656 |
vesicle transport along microtubule
|
471.09 | 8.61 | 69 | 431 |
GABA receptor binding
|
693.28 | 7.69 | 45 | 191 |
cytoplasmic vesicle
|
184.26 | 5.83 | 200 | 3,194 |
BLOC-3 complex
|
1,159.20 | 5.43 | 26 | 66 |
Totals | 2257 | 38764 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pombe | 61 |
goslim_yeast | 163 |
goslim_chembl | 296 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-10-14 | Deleted | RELATION | is a GO:0006886 (intracellular protein transport) |
2023-10-14 | Added | RELATION | is a GO:0045184 (establishment of protein localization) |
2022-01-12 | Deleted | SUBSET | goslim_drosophila |
2021-11-15 | Deleted | SUBSET | goslim_generic |
2020-02-28 | Deleted | XREF | MIPS_funcat:14.04 |
2020-02-28 | Deleted | XREF | MIPS_funcat:14 |
2019-11-09 | Added | SUBSET | goslim_drosophila |
2019-05-04 | Added | XREF | MIPS_funcat:14.04 |
2019-05-04 | Added | XREF | MIPS_funcat:14 |
2016-06-22 | Deleted | RELATION | is a GO:1902582 (single-organism intracellular transport) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | protein targeting |
2001-04-03 | Updated | TERM | protein targeting |
2001-03-30 | Added | TERM | protein targeting |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-03-03 | Added | DEFINITION | The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2016-03-03 | Deleted | DEFINITION | The process of targeting specific proteins to particular regions of the cell, typcially membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2016-03-02 | Added | DEFINITION | The process of targeting specific proteins to particular regions of the cell, typcially membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2016-03-02 | Deleted | DEFINITION | The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2008-07-20 | Added | SYNONYM | protein sorting along secretory pathway |
2008-05-13 | Added | DEFINITION | The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2008-05-12 | Deleted | DEFINITION | The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2008-04-27 | Updated | DEFINITION | The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
2007-08-09 | Deleted | SYNONYM | nascent polypeptide association |
2007-08-09 | Added | SYNONYM | nascent polypeptide association |
2005-10-08 | Added | SYNONYM | nascent polypeptide association |
2001-08-06 | Added | DEFINITION | The process of targeting specific proteins to particular membrane-bound subcellular organelles. Usually requires an organelle specific protein sequence motif. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-10-14 | Deleted | RELATION | is a GO:0006886 (intracellular protein transport) |
2023-10-14 | Added | RELATION | is a GO:0045184 (establishment of protein localization) |
2016-06-22 | Deleted | RELATION | is a GO:1902582 (single-organism intracellular transport) |
2013-12-20 | Added | RELATION | is a GO:1902582 (single-organism intracellular transport) |
2013-12-20 | Deleted | RELATION | is a GO:0044765 (single-organism transport) |
2012-12-20 | Added | RELATION | is a GO:0044765 (single-organism transport) |
2008-04-01 | Updated | RELATION | is a GO:0006886 (intracellular protein transport) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:14.04 |
2020-02-28 | Deleted | XREF | MIPS_funcat:14 |
2019-05-04 | Added | XREF | MIPS_funcat:14.04 |
2019-05-04 | Added | XREF | MIPS_funcat:14 |
2009-03-02 | Added | XREF | Wikipedia:Protein_targeting |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-01-12 | Deleted | SUBSET | goslim_drosophila |
2021-11-15 | Deleted | SUBSET | goslim_generic |
2019-11-09 | Added | SUBSET | goslim_drosophila |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2013-04-18 | Updated | SUBSET | goslim_generic |
2013-04-18 | Updated | SUBSET | goslim_yeast |
2013-04-18 | Updated | SUBSET | goslim_pombe |
2011-08-14 | Added | SUBSET | goslim_yeast |
2010-12-05 | Added | SUBSET | goslim_generic |
2009-05-11 | Added | SUBSET | goslim_pombe |
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