This term is obsolete.

GO:0006605 JSON

protein targeting

Biological Process

Definition (GO:0006605 GONUTS page)

The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

978,452 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
nascent polypeptide association related
protein sorting along secretory pathway narrow

Ancestor Chart

Ancestor chart for GO:0006605
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006605

Child Term Relationship to
GO:0006605
protein targeting to Golgi apparatus
is_a
protein targeting to vacuole
is_a
protein targeting to chloroplast
is_a
protein targeting to ER
is_a
protein targeting to peroxisome
is_a
protein targeting to mitochondrion
is_a
regulation of protein targeting
regulates
protein targeting to membrane
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02650 10116 APOE_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P04639 10116 APOA1_RAT GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P08226 10090 APOE_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076
NOT-qualified manual protein Q00623 10090 APOA1_MOUSE GO:0008104 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9325076

Cross-references

Database ID Description
InterPro IPR000185 Protein translocase subunit SecA
InterPro IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit
InterPro IPR002010 Type III secretion system inner membrane R protein
InterPro IPR002056 Protein import receptor MAS20
InterPro IPR020937 SecA conserved site
InterPro IPR022422 Protein import receptor MAS20, metazoan
Wikipedia Protein_targeting

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006605 based on ALL annotations
The top 100 of 1,458 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein targeting
642.93 100.00 303,203 303,203
protein transport by the Sec complex
556.46 57.35 190,902 220,569
intracellular protein transmembrane transport
459.05 49.39 186,667 261,441
intracellular protein transport
181.81 23.22 171,263 605,631
protein-transporting ATPase activity
376.52 18.92 66,223 113,080
signal recognition particle binding
540.79 17.52 54,949 65,327
cell envelope Sec protein transport complex
642.89 17.20 52,139 52,142
protein import
246.44 14.40 56,835 148,276
SRP-dependent cotranslational protein targeting to membrane
245.88 14.02 54,937 143,652
protein transmembrane transporter activity
154.33 10.35 46,696 194,531
Totals 2612976 211379922
No co-occurrence statistics for GO:0006605 based on MANUAL annotations
The top 100 of 894 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein targeting
2,942.59 100.00 439 439
Golgi to lysosome transport
1,307.82 16.03 88 198
mitochondrion distribution
1,770.76 14.05 68 113
myosin binding
794.20 12.00 78 289
anterograde axonal transport of mitochondrion
2,238.03 11.84 54 71
signal recognition particle binding
470.99 10.61 105 656
vesicle transport along microtubule
471.09 8.61 69 431
GABA receptor binding
693.28 7.69 45 191
cytoplasmic vesicle
184.26 5.83 200 3,194
BLOC-3 complex
1,159.20 5.43 26 66
Totals 2257 38764

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pombe 61
goslim_yeast 163
goslim_chembl 296

Change Log

Timestamp Action Category Detail
2023-10-14 Deleted RELATION is a GO:0006886 (intracellular protein transport)
2023-10-14 Added RELATION is a GO:0045184 (establishment of protein localization)
2022-01-12 Deleted SUBSET goslim_drosophila
2021-11-15 Deleted SUBSET goslim_generic
2020-02-28 Deleted XREF MIPS_funcat:14.04
2020-02-28 Deleted XREF MIPS_funcat:14
2019-11-09 Added SUBSET goslim_drosophila
2019-05-04 Added XREF MIPS_funcat:14.04
2019-05-04 Added XREF MIPS_funcat:14
2016-06-22 Deleted RELATION is a GO:1902582 (single-organism intracellular transport)
Timestamp Action Category Detail
2002-02-06 Updated TERM protein targeting
2001-04-03 Updated TERM protein targeting
2001-03-30 Added TERM protein targeting
Timestamp Action Category Detail
2016-03-03 Added DEFINITION The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2016-03-03 Deleted DEFINITION The process of targeting specific proteins to particular regions of the cell, typcially membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2016-03-02 Added DEFINITION The process of targeting specific proteins to particular regions of the cell, typcially membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2016-03-02 Deleted DEFINITION The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2008-07-20 Added SYNONYM protein sorting along secretory pathway
2008-05-13 Added DEFINITION The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2008-05-12 Deleted DEFINITION The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2008-04-27 Updated DEFINITION The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
2007-08-09 Deleted SYNONYM nascent polypeptide association
2007-08-09 Added SYNONYM nascent polypeptide association
2005-10-08 Added SYNONYM nascent polypeptide association
2001-08-06 Added DEFINITION The process of targeting specific proteins to particular membrane-bound subcellular organelles. Usually requires an organelle specific protein sequence motif.
Timestamp Action Category Detail
2023-10-14 Deleted RELATION is a GO:0006886 (intracellular protein transport)
2023-10-14 Added RELATION is a GO:0045184 (establishment of protein localization)
2016-06-22 Deleted RELATION is a GO:1902582 (single-organism intracellular transport)
2013-12-20 Added RELATION is a GO:1902582 (single-organism intracellular transport)
2013-12-20 Deleted RELATION is a GO:0044765 (single-organism transport)
2012-12-20 Added RELATION is a GO:0044765 (single-organism transport)
2008-04-01 Updated RELATION is a GO:0006886 (intracellular protein transport)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:14.04
2020-02-28 Deleted XREF MIPS_funcat:14
2019-05-04 Added XREF MIPS_funcat:14.04
2019-05-04 Added XREF MIPS_funcat:14
2009-03-02 Added XREF Wikipedia:Protein_targeting
Timestamp Action Category Detail
2022-01-12 Deleted SUBSET goslim_drosophila
2021-11-15 Deleted SUBSET goslim_generic
2019-11-09 Added SUBSET goslim_drosophila
2015-05-19 Added SUBSET goslim_chembl
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-11 Added SUBSET goslim_ChEMBL
2013-04-18 Updated SUBSET goslim_generic
2013-04-18 Updated SUBSET goslim_yeast
2013-04-18 Updated SUBSET goslim_pombe
2011-08-14 Added SUBSET goslim_yeast
2010-12-05 Added SUBSET goslim_generic
2009-05-11 Added SUBSET goslim_pombe
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