This term is obsolete.

GO:0006878 JSON

intracellular copper ion homeostasis

Biological Process

Definition (GO:0006878 GONUTS page)

A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.

16,748 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
copper homeostasis broad
cellular copper ion homeostasis exact

Ancestor Chart

Ancestor chart for GO:0006878
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006878 intracellular copper ion homeostasis Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6JGR9 10116 A6JGR9_RAT GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZJB7 10116 D3ZJB7_RAT GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q6XR72 9606 ZNT10_HUMAN GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25319704

Cross-references

Database ID Description
InterPro IPR007939 Copper resistance B precursor
InterPro IPR017276 Synthesis of cytochrome c oxidase, Sco1/Sco2
InterPro IPR044671 Metallothionein-like protein 3

Cross-Ontology Relations

Relation Other Ontology ID Term
regulates_levels_of CHEBI CHEBI:23378 copper cation

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006878 based on ALL annotations
The top 100 of 792 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intracellular copper ion homeostasis
11,959.37 100.00 16,569 16,569
respiratory chain complex IV assembly
3,153.13 9.55 2,158 8,185
copper chaperone activity
3,079.86 9.49 2,164 8,403
mitochondrial cytochrome c oxidase assembly
565.41 3.61 2,200 46,534
intracellular iron ion homeostasis
458.70 3.50 4,785 124,756
voltage-gated chloride channel activity
575.15 3.38 1,694 35,224
copper ion import
583.53 3.20 1,410 28,898
fungal-type vacuole
424.65 2.71 1,694 47,708
P-type monovalent copper transporter activity
1,077.42 2.52 560 6,216
copper ion binding
288.26 2.40 14,113 585,529
Totals 78854 4489770
No co-occurrence statistics for GO:0006878 based on MANUAL annotations
The top 100 of 653 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intracellular copper ion homeostasis
6,786.22 100.00 208 208
copper ion export
4,214.60 24.18 59 95
copper ion import
1,696.55 15.60 61 244
P-type divalent copper transporter activity
1,036.78 10.72 55 360
copper ion transport
1,761.81 9.47 27 104
copper ion transmembrane transport
4,643.20 6.07 13 19
copper ion binding
371.51 5.26 120 2,192
collateral sprouting in absence of injury
4,147.13 5.12 11 18
mating behavior
1,422.92 5.06 13 62
copper ion transmembrane transporter activity
511.43 4.93 26 345
Totals 1211 23308

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-12-24 Deleted RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2022-12-24 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2022-12-12 Added SYNONYM cellular copper ion homeostasis
2022-12-12 Deleted DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2022-12-12 Updated TERM intracellular copper ion homeostasis
2022-12-12 Added DEFINITION A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
2013-07-04 Added RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2013-07-04 Deleted RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2010-12-19 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
Timestamp Action Category Detail
2022-12-12 Updated TERM intracellular copper ion homeostasis
2007-07-15 Updated TERM cellular copper ion homeostasis
2003-02-19 Updated TERM copper ion homeostasis
2002-02-06 Updated TERM copper homeostasis
2001-04-03 Updated TERM copper homeostasis
2001-03-30 Added TERM copper homeostasis
Timestamp Action Category Detail
2022-12-12 Added SYNONYM cellular copper ion homeostasis
2022-12-12 Deleted DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2022-12-12 Added DEFINITION A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
2010-12-01 Deleted DEFINITION Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell.
2010-12-01 Added DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2010-03-13 Added DEFINITION Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell.
2010-03-13 Deleted DEFINITION Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell.
2009-01-12 Added DEFINITION Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell.
2009-01-12 Deleted DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2008-05-13 Added DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2008-05-12 Deleted DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2007-08-09 Deleted SYNONYM copper homeostasis
2007-08-09 Added SYNONYM copper homeostasis
2004-04-19 Added SYNONYM copper homeostasis
2004-04-16 Deleted SYNONYM copper homeostasis
2003-02-19 Added SYNONYM copper homeostasis
2002-11-27 Added DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
Timestamp Action Category Detail
2022-12-24 Deleted RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2022-12-24 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2013-07-04 Added RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2013-07-04 Deleted RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2010-12-19 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2010-12-19 Deleted RELATION is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis)
2008-04-01 Updated RELATION is a GO:0055070 (copper ion homeostasis)
2008-04-01 Updated RELATION is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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