GO:0006878
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intracellular copper ion homeostasis
Biological Process
Definition (GO:0006878 GONUTS page)
A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
copper homeostasis | broad |
cellular copper ion homeostasis | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0006878 | intracellular copper ion homeostasis | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A6JGR9 | 10116 | A6JGR9_RAT | GO:0006878 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZJB7 | 10116 | D3ZJB7_RAT | GO:0006878 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q6XR72 | 9606 | ZNT10_HUMAN | GO:0006878 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25319704 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR007939 | Copper resistance B precursor |
InterPro | IPR017276 | Synthesis of cytochrome c oxidase, Sco1/Sco2 |
InterPro | IPR044671 | Metallothionein-like protein 3 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
regulates_levels_of | CHEBI | CHEBI:23378 | copper cation |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0006878 based on ALL annotations
The top 100 of 792 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intracellular copper ion homeostasis
|
11,959.37 | 100.00 | 16,569 | 16,569 |
respiratory chain complex IV assembly
|
3,153.13 | 9.55 | 2,158 | 8,185 |
copper chaperone activity
|
3,079.86 | 9.49 | 2,164 | 8,403 |
mitochondrial cytochrome c oxidase assembly
|
565.41 | 3.61 | 2,200 | 46,534 |
intracellular iron ion homeostasis
|
458.70 | 3.50 | 4,785 | 124,756 |
voltage-gated chloride channel activity
|
575.15 | 3.38 | 1,694 | 35,224 |
copper ion import
|
583.53 | 3.20 | 1,410 | 28,898 |
fungal-type vacuole
|
424.65 | 2.71 | 1,694 | 47,708 |
P-type monovalent copper transporter activity
|
1,077.42 | 2.52 | 560 | 6,216 |
copper ion binding
|
288.26 | 2.40 | 14,113 | 585,529 |
Totals | 78854 | 4489770 |
No co-occurrence statistics for GO:0006878 based on MANUAL annotations
The top 100 of 653 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intracellular copper ion homeostasis
|
6,786.22 | 100.00 | 208 | 208 |
copper ion export
|
4,214.60 | 24.18 | 59 | 95 |
copper ion import
|
1,696.55 | 15.60 | 61 | 244 |
P-type divalent copper transporter activity
|
1,036.78 | 10.72 | 55 | 360 |
copper ion transport
|
1,761.81 | 9.47 | 27 | 104 |
copper ion transmembrane transport
|
4,643.20 | 6.07 | 13 | 19 |
copper ion binding
|
371.51 | 5.26 | 120 | 2,192 |
collateral sprouting in absence of injury
|
4,147.13 | 5.12 | 11 | 18 |
mating behavior
|
1,422.92 | 5.06 | 13 | 62 |
copper ion transmembrane transporter activity
|
511.43 | 4.93 | 26 | 345 |
Totals | 1211 | 23308 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-12-24 | Deleted | RELATION | is a GO:0046916 (obsolete intracellular transition metal ion homeostasis) |
2022-12-24 | Added | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
2022-12-12 | Added | SYNONYM | cellular copper ion homeostasis |
2022-12-12 | Deleted | DEFINITION | Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell. |
2022-12-12 | Updated | TERM | intracellular copper ion homeostasis |
2022-12-12 | Added | DEFINITION | A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell. |
2013-07-04 | Added | RELATION | is a GO:0046916 (obsolete intracellular transition metal ion homeostasis) |
2013-07-04 | Deleted | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
2010-12-19 | Added | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-12-12 | Updated | TERM | intracellular copper ion homeostasis |
2007-07-15 | Updated | TERM | cellular copper ion homeostasis |
2003-02-19 | Updated | TERM | copper ion homeostasis |
2002-02-06 | Updated | TERM | copper homeostasis |
2001-04-03 | Updated | TERM | copper homeostasis |
2001-03-30 | Added | TERM | copper homeostasis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-12-12 | Added | SYNONYM | cellular copper ion homeostasis |
2022-12-12 | Deleted | DEFINITION | Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell. |
2022-12-12 | Added | DEFINITION | A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell. |
2010-12-01 | Deleted | DEFINITION | Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell. |
2010-12-01 | Added | DEFINITION | Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell. |
2010-03-13 | Added | DEFINITION | Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell. |
2010-03-13 | Deleted | DEFINITION | Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell. |
2009-01-12 | Added | DEFINITION | Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell. |
2009-01-12 | Deleted | DEFINITION | The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment. |
2008-05-13 | Added | DEFINITION | The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment. |
2008-05-12 | Deleted | DEFINITION | The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment. |
2007-08-09 | Deleted | SYNONYM | copper homeostasis |
2007-08-09 | Added | SYNONYM | copper homeostasis |
2004-04-19 | Added | SYNONYM | copper homeostasis |
2004-04-16 | Deleted | SYNONYM | copper homeostasis |
2003-02-19 | Added | SYNONYM | copper homeostasis |
2002-11-27 | Added | DEFINITION | The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-12-24 | Deleted | RELATION | is a GO:0046916 (obsolete intracellular transition metal ion homeostasis) |
2022-12-24 | Added | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
2013-07-04 | Added | RELATION | is a GO:0046916 (obsolete intracellular transition metal ion homeostasis) |
2013-07-04 | Deleted | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
2010-12-19 | Added | RELATION | is a GO:0030003 (intracellular monoatomic cation homeostasis) |
2010-12-19 | Deleted | RELATION | is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis) |
2008-04-01 | Updated | RELATION | is a GO:0055070 (copper ion homeostasis) |
2008-04-01 | Updated | RELATION | is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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