This term is obsolete.

GO:0006878 JSON

intracellular copper ion homeostasis

Biological Process

Definition (GO:0006878 GONUTS page)

A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.

16,502 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
copper homeostasis broad
cellular copper ion homeostasis exact

Ancestor Chart

Ancestor chart for GO:0006878
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006878

Child Term Relationship to
GO:0006878
sequestering of copper ion
is_a
extracellular sequestering of copper ion
part_of
intracellular sequestering of copper ion
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006878 intracellular copper ion homeostasis Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6JGR9 10116 A6JGR9_RAT GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZJB7 10116 D3ZJB7_RAT GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q6XR72 9606 ZNT10_HUMAN GO:0006878 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25319704

Cross-references

Database ID Description
InterPro IPR007939 Copper resistance B precursor
InterPro IPR017276 Synthesis of cytochrome c oxidase, Sco1/Sco2
InterPro IPR044671 Metallothionein-like protein 3

Cross-Ontology Relations

Relation Other Ontology ID Term
regulates_levels_of CHEBI CHEBI:23378 copper cation

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006878 based on ALL annotations
The top 100 of 809 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intracellular copper ion homeostasis
11,930.16 100.00 16,340 16,340
respiratory chain complex IV assembly
3,104.44 9.42 2,101 8,074
copper chaperone activity
3,082.76 9.41 2,107 8,154
mitochondrial cytochrome c oxidase assembly
567.65 3.62 2,144 45,060
intracellular iron ion homeostasis
463.29 3.55 4,747 122,241
copper ion import
570.24 3.13 1,358 28,411
fungal-type vacuole
425.16 2.72 1,684 47,254
P-type monovalent copper transporter activity
1,050.60 2.51 554 6,291
copper ion binding
289.21 2.41 13,894 573,134
copper ion export
378.00 2.30 1,256 39,641
Totals 76165 4373929
No co-occurrence statistics for GO:0006878 based on MANUAL annotations
The top 100 of 663 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intracellular copper ion homeostasis
6,945.16 100.00 186 186
copper ion export
3,340.71 16.74 38 79
copper ion import
1,292.12 11.08 40 215
copper ion transport
1,887.27 9.88 25 92
P-type divalent copper transporter activity
711.25 7.02 34 332
copper ion transmembrane transport
4,514.35 6.74 13 20
collateral sprouting in absence of injury
4,244.26 5.70 11 18
mating behavior
1,456.24 5.53 13 62
copper ion transmembrane transporter activity
543.90 5.28 26 332
copper ion binding
332.17 4.59 98 2,049
Totals 1047 17062

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-12-24 Deleted RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2022-12-24 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2022-12-12 Added SYNONYM cellular copper ion homeostasis
2022-12-12 Deleted DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2022-12-12 Updated TERM intracellular copper ion homeostasis
2022-12-12 Added DEFINITION A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
2013-07-04 Deleted RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2013-07-04 Added RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2010-12-19 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
Timestamp Action Category Detail
2022-12-12 Updated TERM intracellular copper ion homeostasis
2007-07-15 Updated TERM cellular copper ion homeostasis
2003-02-19 Updated TERM copper ion homeostasis
2002-02-06 Updated TERM copper homeostasis
2001-04-03 Updated TERM copper homeostasis
2001-03-30 Added TERM copper homeostasis
Timestamp Action Category Detail
2022-12-12 Added SYNONYM cellular copper ion homeostasis
2022-12-12 Deleted DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2022-12-12 Added DEFINITION A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
2010-12-01 Deleted DEFINITION Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell.
2010-12-01 Added DEFINITION Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
2010-03-13 Added DEFINITION Any process involved in the maintenance of an internal steady-state of copper ions at the level of a cell.
2010-03-13 Deleted DEFINITION Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell.
2009-01-12 Deleted DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2009-01-12 Added DEFINITION Any process involved in the maintenance of an internal equilibrium of copper ions at the level of a cell.
2008-05-13 Added DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2008-05-12 Deleted DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
2007-08-09 Deleted SYNONYM copper homeostasis
2007-08-09 Added SYNONYM copper homeostasis
2004-04-19 Added SYNONYM copper homeostasis
2004-04-16 Deleted SYNONYM copper homeostasis
2003-02-19 Added SYNONYM copper homeostasis
2002-11-27 Added DEFINITION The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment.
Timestamp Action Category Detail
2022-12-24 Deleted RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2022-12-24 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2013-07-04 Deleted RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2013-07-04 Added RELATION is a GO:0046916 (obsolete intracellular transition metal ion homeostasis)
2010-12-19 Added RELATION is a GO:0030003 (intracellular monoatomic cation homeostasis)
2010-12-19 Deleted RELATION is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis)
2008-04-01 Updated RELATION is a GO:0030005 (obsolete cellular di-, tri-valent inorganic cation homeostasis)
2008-04-01 Updated RELATION is a GO:0055070 (copper ion homeostasis)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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