This term is obsolete.

GO:0006952 JSON

defense response

Biological Process

Definition (GO:0006952 GONUTS page)

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

Secondary IDs

GO:0002217, GO:0042829

1,327,226 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
antimicrobial peptide activity related
physiological defense response exact
defense/immunity protein activity related
defence response exact

Ancestor Chart

Ancestor chart for GO:0006952
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0006952

Child Term Relationship to
GO:0006952
regulation of defense response
regulates
defense response by callose deposition
is_a
defense response to tumor cell
is_a
positive regulation of defense response
positively_regulates
defense response by cell wall thickening
is_a
negative regulation of defense response
negatively_regulates
cellular defense response
is_a
respiratory burst involved in defense response
part_of
defense response to other organism
is_a
inflammatory response
is_a

Cross-references

Database ID Description
InterPro IPR000471 Interferon alpha/beta/delta
InterPro IPR000767 Disease resistance protein
InterPro IPR000916 Bet v I/Major latex protein
InterPro IPR001010 Thionin
InterPro IPR001329 Glycoside hydrolase family 56, bee venom hyaluronidase
InterPro IPR001542 Defensin, invertebrate/fungal
InterPro IPR001855 Beta-defensin-like domain
InterPro IPR001894 Cathelicidin-like
InterPro IPR002186 Neocarzinostatin family
InterPro IPR002366 Alpha-defensin, N-terminal

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0003793 obsolete defense/immunity protein activity consider GO:0006952
GO:0043499 obsolete eukaryotic cell surface binding consider GO:0006952

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0006952 based on ALL annotations
The top 100 of 4,250 co-occurring terms
Co-occurring Term PR S% #Together #Compared
defense response
819.36 100.00 237,916 237,916
response to other organism
667.05 26.02 65,809 80,835
ADP binding
278.86 23.29 101,031 296,853
defense response to other organism
402.04 11.49 31,026 63,231
superoxide-generating NAD(P)H oxidase activity
770.68 4.75 11,335 12,051
NADPH oxidase complex
632.62 4.70 11,335 14,681
superoxide anion generation
459.23 4.59 11,335 20,224
plant-type hypersensitive response
685.15 3.47 8,316 9,945
abscisic acid-activated signaling pathway
348.24 3.24 8,071 18,990
cytokine activity
59.73 3.11 12,243 167,953
Totals 778607 21683035
No co-occurrence statistics for GO:0006952 based on MANUAL annotations
The top 100 of 1,882 co-occurring terms
Co-occurring Term PR S% #Together #Compared
defense response
460.21 100.00 2,807 2,807
superoxide-generating NAD(P)H oxidase activity
375.94 6.11 174 213
NADPH oxidase complex
319.03 6.03 174 251
superoxide anion generation
221.20 5.81 174 362
cell surface receptor signaling pathway via JAK-STAT
157.23 5.65 178 521
regulation of cell population proliferation
62.28 4.49 177 1,308
response to peptide hormone
138.16 4.35 136 453
cell surface receptor signaling pathway
18.18 2.36 155 3,923
growth hormone receptor signaling pathway via JAK-STAT
204.54 2.35 68 153
stearoyl-CoA 9-desaturase activity
152.65 2.31 68 205
Totals 6840 223540

Change Log

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2008-05-12 Deleted DEFINITION Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2008-05-11 Added RELATION is a GO:0006950 (response to stress)
2008-05-11 Deleted RELATION is a GO:0050896 (response to stimulus)
2008-04-01 Updated RELATION is a GO:0050896 (response to stimulus)
2007-08-09 Deleted SYNONYM antimicrobial peptide activity
2007-08-09 Deleted SYNONYM physiological defense response
2007-08-09 Added SYNONYM physiological defense response
2007-08-09 Added SYNONYM defense/immunity protein activity
2007-08-09 Added SYNONYM defence response
Timestamp Action Category Detail
2002-02-06 Updated TERM defense response
2001-04-03 Updated TERM defense response
2001-03-30 Added TERM defense response
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2008-05-12 Deleted DEFINITION Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2007-08-09 Deleted SYNONYM antimicrobial peptide activity
2007-08-09 Deleted SYNONYM physiological defense response
2007-08-09 Added SYNONYM physiological defense response
2007-08-09 Added SYNONYM defense/immunity protein activity
2007-08-09 Added SYNONYM defence response
2007-08-09 Added SYNONYM antimicrobial peptide activity
2007-08-09 Deleted SYNONYM defence response
2007-08-09 Deleted SYNONYM defense/immunity protein activity
2007-01-15 Added SYNONYM physiological defense response
2005-08-10 Added SYNONYM antimicrobial peptide activity
2005-08-10 Added SYNONYM defense/immunity protein activity
2004-05-29 Added SYNONYM defence response
2001-08-06 Added DEFINITION Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
Timestamp Action Category Detail
2008-05-11 Added RELATION is a GO:0006950 (response to stress)
2008-05-11 Deleted RELATION is a GO:0050896 (response to stimulus)
2008-04-01 Updated RELATION is a GO:0050896 (response to stimulus)
Timestamp Action Category Detail
Timestamp Action Category Detail
2007-01-15 Added SECONDARY GO:0002217 (physiological defense response)
2007-01-15 Added SECONDARY GO:0042829 (defense response to pathogen)
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