GO:0007267
JSON
cell-cell signaling
Biological Process
Definition (GO:0007267 GONUTS page)
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
cell-cell signalling | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007267
Child Term | Relationship to GO:0007267 |
---|---|
endodermal-mesodermal cell signaling
|
is_a |
cerebellar Purkinje cell-granule cell precursor cell signaling
|
is_a |
synaptic signaling
|
is_a |
regulation of pre-tubular aggregate formation by cell-cell signaling
|
is_a |
c-di-GMP signaling
|
is_a |
visceral mesoderm-endoderm interaction involved in midgut development
|
is_a |
cell-cell signaling involved in placenta development
|
is_a |
epiblast cell-extraembryonic ectoderm cell signaling
|
is_a |
mesenchymal-epithelial cell signaling
|
is_a |
ectoderm and mesoderm interaction
|
is_a |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
---|---|
signalling | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000320 | Hedgehog, N-terminal signalling domain |
InterPro | IPR001657 | Hedgehog protein |
InterPro | IPR002261 | Gap junction alpha-1 protein (Cx43) |
InterPro | IPR017289 | SH2 protein 1A |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0003001 | obsolete generation of a signal involved in cell-cell signaling | consider GO:0007267 |
GO:0023017 | obsolete signal transmission via diffusible molecule | consider GO:0007267 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007267 based on ALL annotations
The top 100 of 3,526 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cell-cell signaling
|
5,169.57 | 100.00 | 38,331 | 38,331 |
connexin complex
|
5,026.36 | 49.03 | 19,058 | 19,601 |
gap junction
|
3,044.81 | 38.34 | 20,065 | 34,067 |
gap junction channel activity
|
3,466.85 | 37.50 | 17,618 | 26,271 |
cell communication
|
1,040.34 | 16.49 | 18,292 | 90,895 |
patched binding
|
2,941.93 | 11.11 | 4,650 | 8,171 |
positive regulation of interleukin-1 production
|
4,622.34 | 9.41 | 3,649 | 4,081 |
wide pore channel activity
|
2,653.94 | 8.73 | 3,646 | 7,102 |
alpha1-adrenergic receptor activity
|
4,994.46 | 8.68 | 3,337 | 3,454 |
protein autoprocessing
|
1,321.31 | 8.62 | 4,409 | 17,250 |
Totals | 227256 | 3077708 |
No co-occurrence statistics for GO:0007267 based on MANUAL annotations
The top 100 of 2,809 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cell-cell signaling
|
1,268.22 | 100.00 | 1,113 | 1,113 |
connexin complex
|
1,242.39 | 42.83 | 481 | 491 |
gap junction channel activity
|
967.29 | 35.91 | 450 | 590 |
alpha1-adrenergic receptor activity
|
1,217.49 | 6.45 | 72 | 75 |
gap junction-mediated intercellular transport
|
1,152.93 | 6.25 | 70 | 77 |
wide pore channel activity
|
584.57 | 4.99 | 59 | 128 |
adenylate cyclase-activating adrenergic receptor signaling pathway
|
209.43 | 4.87 | 72 | 436 |
growth factor binding
|
238.88 | 4.07 | 55 | 292 |
phospholipase C-activating G protein-coupled receptor signaling pathway
|
112.16 | 4.07 | 78 | 882 |
positive regulation of MAPK cascade
|
71.07 | 3.85 | 122 | 2,177 |
Totals | 5507 | 37726 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_plant | 97 |
goslim_chembl | 296 |
Change Log
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- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2022-11-08 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2021-11-15 | Deleted | SUBSET | goslim_generic |
2017-08-13 | Deleted | RELATION | is a GO:0044700 (single organism signaling) |
2017-08-13 | Deleted | RELATION | is a GO:0044763 (single-organism cellular process) |
2017-08-13 | Added | RELATION | is a GO:0023052 (signaling) |
2016-12-17 | Added | RELATION | is a GO:0044763 (single-organism cellular process) |
2016-05-21 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the recieving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2016-05-21 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2016-05-20 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | cell-cell signaling |
2001-04-03 | Updated | TERM | cell-cell signaling |
2001-03-30 | Added | TERM | cell-cell signaling |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-08 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2022-11-08 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2016-05-21 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the recieving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2016-05-21 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2016-05-20 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. |
2016-05-20 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the recieving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
2011-02-27 | Deleted | SYNONYM | paracrine signaling |
2010-04-30 | Added | SYNONYM | paracrine signaling |
2010-04-30 | Deleted | SYNONYM | paracrine signaling |
2010-03-31 | Added | SYNONYM | paracrine signaling |
2008-05-13 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. |
2008-05-12 | Deleted | DEFINITION | Any process that mediates the transfer of information from one cell to another. |
2007-08-09 | Added | SYNONYM | cell-cell signalling |
2007-08-09 | Deleted | SYNONYM | cell-cell signalling |
2004-04-19 | Added | SYNONYM | cell-cell signalling |
2004-04-16 | Deleted | SYNONYM | cell-cell signalling |
2003-11-13 | Added | SYNONYM | cell-cell signalling |
2001-08-06 | Added | DEFINITION | Any process that mediates the transfer of information from one cell to another. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-13 | Deleted | RELATION | is a GO:0044700 (single organism signaling) |
2017-08-13 | Deleted | RELATION | is a GO:0044763 (single-organism cellular process) |
2017-08-13 | Added | RELATION | is a GO:0023052 (signaling) |
2016-12-17 | Added | RELATION | is a GO:0044763 (single-organism cellular process) |
2012-09-29 | Deleted | RELATION | is a GO:0023052 (signaling) |
2012-09-29 | Added | RELATION | is a GO:0044700 (single organism signaling) |
2010-04-15 | Deleted | RELATION | is a GO:0023060 (obsolete signal transmission) |
2010-03-31 | Added | RELATION | is a GO:0023052 (signaling) |
2010-02-20 | Added | RELATION | is a GO:0023060 (obsolete signal transmission) |
2008-04-01 | Updated | RELATION | is a GO:0007154 (cell communication) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-11-15 | Deleted | SUBSET | goslim_generic |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2013-04-18 | Updated | SUBSET | goslim_plant |
2013-04-18 | Updated | SUBSET | goslim_generic |
2008-06-09 | Added | SUBSET | goslim_generic |
2008-06-09 | Added | SUBSET | goslim_plant |
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