This term is obsolete.

GO:0007420 JSON

brain development

Biological Process

Definition (GO:0007420 GONUTS page)

The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).

185,486 annotations

Ancestor Chart

Ancestor chart for GO:0007420
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007420

Child Term Relationship to
GO:0007420
mushroom body development
part_of
central complex development
part_of
hindbrain development
part_of
midbrain development
part_of
forebrain development
part_of
midbrain-hindbrain boundary development
part_of
brain morphogenesis
part_of
brain segmentation
part_of
trigeminal sensory nucleus development
part_of
ventricular system development
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0007420 brain development Only in Taxon 33213 Bilateria

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q54NG5 44689 Q54NG5_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
IEA Review protein Q54NG6 44689 Q54NG6_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
NOT-qualified manual protein Q9VIP7 7227 ACASE_DROME GO:0007420 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21148295

Cross-references

Database ID Description
InterPro IPR002969 Apolipoprotein D
InterPro IPR016362 POU-domain transcription factor, class 3
InterPro IPR024885 Neuronatin
InterPro IPR026222 Apolipoprotein D, vertebrates
InterPro IPR047161 ARF GTPase-activating protein Git-like

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007420 based on ALL annotations
The top 100 of 4,548 co-occurring terms
Co-occurring Term PR S% #Together #Compared
brain development
2,546.16 100.00 77,825 77,825
cell-cell adhesion mediator activity
1,094.13 17.64 17,924 41,711
neuron differentiation
368.62 10.10 19,480 134,553
axon guidance
289.55 8.68 20,845 183,301
synaptic vesicle recycling
2,422.83 7.14 5,579 5,863
axon
222.54 6.86 18,776 214,819
cell-cell adhesion
217.95 6.68 18,151 212,046
endoplasmic reticulum tubular network formation
1,892.24 6.53 5,200 6,997
regulation of G protein-coupled receptor signaling pathway
456.87 5.55 5,790 32,268
DNA-binding transcription activator activity, RNA polymerase II-specific
185.73 5.08 11,141 152,734
Totals 461849 10289084
No co-occurrence statistics for GO:0007420 based on MANUAL annotations
The top 100 of 4,083 co-occurring terms
Co-occurring Term PR S% #Together #Compared
brain development
633.26 100.00 2,229 2,229
neuron differentiation
114.97 11.15 500 2,754
eye development
263.25 9.82 254 611
DNA-binding transcription activator activity, RNA polymerase II-specific
66.37 7.03 392 3,740
animal organ morphogenesis
113.10 6.51 207 1,159
central nervous system development
83.23 5.92 217 1,651
forebrain development
161.76 4.95 129 505
sensory organ development
110.35 4.03 111 637
embryonic organ development
135.89 3.85 100 466
neuron development
102.77 3.79 105 647
Totals 10915 160112

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
2020-02-28 Deleted XREF MIPS_funcat:47.03.01.01.01
2019-05-04 Added XREF MIPS_funcat:47.03.01.01.01
2017-08-13 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2014-11-23 Added RELATION part of GO:0060322 (head development)
2012-12-23 Added RELATION is a GO:0044767 (single-organism developmental process)
2010-05-14 Added DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2010-05-14 Deleted DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2008-05-13 Added DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2008-05-12 Deleted DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
Timestamp Action Category Detail
2002-02-06 Updated TERM brain development
2001-04-03 Updated TERM brain development
2001-03-30 Added TERM brain development
Timestamp Action Category Detail
2010-05-14 Added DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2010-05-14 Deleted DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2008-05-13 Added DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2008-05-12 Deleted DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2005-07-06 Updated DEFINITION The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2005-06-16 Updated DEFINITION The process aimed at the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2004-07-17 Updated DEFINITION Processes aimed at the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2003-11-26 Updated DEFINITION Formation and development of the brain; one of the two components of the central nervous system, the brain is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2003-07-30 Updated DEFINITION Formation and development of the brain; one of the two components of the central nervous system, the brain is the centre of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2003-07-29 Added DEFINITION Formation and development of the brain; one of the two components of the central nervous system, the brain is the centre of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
Timestamp Action Category Detail
2017-08-13 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2014-11-23 Added RELATION part of GO:0060322 (head development)
2012-12-23 Added RELATION is a GO:0044767 (single-organism developmental process)
2008-04-01 Updated RELATION part of GO:0007417 (central nervous system development)
2008-04-01 Updated RELATION is a GO:0048513 (animal organ development)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:47.03.01.01.01
2019-05-04 Added XREF MIPS_funcat:47.03.01.01.01
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
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