GO:0007420
JSON
brain development
Biological Process
Definition (GO:0007420 GONUTS page)
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007420
Child Term | Relationship to GO:0007420 |
---|---|
mushroom body development
|
part_of |
central complex development
|
part_of |
hindbrain development
|
part_of |
midbrain development
|
part_of |
forebrain development
|
part_of |
midbrain-hindbrain boundary development
|
part_of |
brain morphogenesis
|
part_of |
brain segmentation
|
part_of |
trigeminal sensory nucleus development
|
part_of |
ventricular system development
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0007420 | brain development | Only in Taxon | 33213 | Bilateria |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q54NG5 | 44689 | Q54NG5_DICDI | GO:0007417 | To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 | IPR034968 |
IEA Review | protein | Q54NG6 | 44689 | Q54NG6_DICDI | GO:0007417 | To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 | IPR034968 |
NOT-qualified manual | protein | Q9VIP7 | 7227 | ACASE_DROME | GO:0007420 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21148295 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR002969 | Apolipoprotein D |
InterPro | IPR016362 | POU-domain transcription factor, class 3 |
InterPro | IPR024885 | Neuronatin |
InterPro | IPR026222 | Apolipoprotein D, vertebrates |
InterPro | IPR047161 | ARF GTPase-activating protein Git-like |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007420 based on ALL annotations
The top 100 of 4,548 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
brain development
|
2,546.16 | 100.00 | 77,825 | 77,825 |
cell-cell adhesion mediator activity
|
1,094.13 | 17.64 | 17,924 | 41,711 |
neuron differentiation
|
368.62 | 10.10 | 19,480 | 134,553 |
axon guidance
|
289.55 | 8.68 | 20,845 | 183,301 |
synaptic vesicle recycling
|
2,422.83 | 7.14 | 5,579 | 5,863 |
axon
|
222.54 | 6.86 | 18,776 | 214,819 |
cell-cell adhesion
|
217.95 | 6.68 | 18,151 | 212,046 |
endoplasmic reticulum tubular network formation
|
1,892.24 | 6.53 | 5,200 | 6,997 |
regulation of G protein-coupled receptor signaling pathway
|
456.87 | 5.55 | 5,790 | 32,268 |
DNA-binding transcription activator activity, RNA polymerase II-specific
|
185.73 | 5.08 | 11,141 | 152,734 |
Totals | 461849 | 10289084 |
No co-occurrence statistics for GO:0007420 based on MANUAL annotations
The top 100 of 4,083 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
brain development
|
633.26 | 100.00 | 2,229 | 2,229 |
neuron differentiation
|
114.97 | 11.15 | 500 | 2,754 |
eye development
|
263.25 | 9.82 | 254 | 611 |
DNA-binding transcription activator activity, RNA polymerase II-specific
|
66.37 | 7.03 | 392 | 3,740 |
animal organ morphogenesis
|
113.10 | 6.51 | 207 | 1,159 |
central nervous system development
|
83.23 | 5.92 | 217 | 1,651 |
forebrain development
|
161.76 | 4.95 | 129 | 505 |
sensory organ development
|
110.35 | 4.03 | 111 | 637 |
embryonic organ development
|
135.89 | 3.85 | 100 | 466 |
neuron development
|
102.77 | 3.79 | 105 | 647 |
Totals | 10915 | 160112 |
Change Log
- All changes
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- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2020-02-28 | Deleted | XREF | MIPS_funcat:47.03.01.01.01 |
2019-05-04 | Added | XREF | MIPS_funcat:47.03.01.01.01 |
2017-08-13 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2014-11-23 | Added | RELATION | part of GO:0060322 (head development) |
2012-12-23 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2010-05-14 | Added | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2010-05-14 | Deleted | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2008-05-13 | Added | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2008-05-12 | Deleted | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | brain development |
2001-04-03 | Updated | TERM | brain development |
2001-03-30 | Added | TERM | brain development |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-05-14 | Added | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2010-05-14 | Deleted | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2008-05-13 | Added | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2008-05-12 | Deleted | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2005-07-06 | Updated | DEFINITION | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2005-06-16 | Updated | DEFINITION | The process aimed at the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2004-07-17 | Updated | DEFINITION | Processes aimed at the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2003-11-26 | Updated | DEFINITION | Formation and development of the brain; one of the two components of the central nervous system, the brain is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2003-07-30 | Updated | DEFINITION | Formation and development of the brain; one of the two components of the central nervous system, the brain is the centre of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
2003-07-29 | Added | DEFINITION | Formation and development of the brain; one of the two components of the central nervous system, the brain is the centre of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-13 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2014-11-23 | Added | RELATION | part of GO:0060322 (head development) |
2012-12-23 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2008-04-01 | Updated | RELATION | part of GO:0007417 (central nervous system development) |
2008-04-01 | Updated | RELATION | is a GO:0048513 (animal organ development) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:47.03.01.01.01 |
2019-05-04 | Added | XREF | MIPS_funcat:47.03.01.01.01 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
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