GO:0007507
JSON
heart development
Biological Process
Definition (GO:0007507 GONUTS page)
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
Secondary IDs
GO:0007511
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
dorsal vessel development | narrow |
cardiac development | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0007507
Child Term | Relationship to GO:0007507 |
---|---|
heart growth
|
part_of |
cardiac jelly development
|
part_of |
endocardium development
|
part_of |
larval heart development
|
is_a |
heart valve development
|
part_of |
heart morphogenesis
|
part_of |
cell surface receptor signaling pathway involved in heart development
|
part_of |
fibroblast growth factor receptor signaling pathway involved in heart development
|
part_of |
cardiac muscle tissue development
|
part_of |
atrioventricular canal development
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0007507 | heart development | Only in Taxon | 33213 | Bilateria |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A1D5NZN4 | 9031 | A0A1D5NZN4_CHICK | GO:0007507 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:17549728 | |
NOT-qualified manual | protein | F7FNP9 | 10116 | F7FNP9_RAT | GO:0007507 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P43680 | 10090 | SOX18_MOUSE | GO:0007507 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11094083 | |
NOT-qualified manual | protein | Q4V7E4 | 10116 | Q4V7E4_RAT | GO:0007507 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000482 | 5-Hydroxytryptamine 2B receptor |
InterPro | IPR002261 | Gap junction alpha-1 protein (Cx43) |
InterPro | IPR037885 | Heat shock protein beta-7, ACD domain |
InterPro | IPR047853 | Apelin receptor early endogenous ligand |
Wikipedia | Heart_development |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0061310 | obsolete canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development | consider GO:0007507 |
GO:0061312 | obsolete BMP signaling pathway involved in heart development | consider GO:0007507 |
GO:1901225 | obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development | consider GO:0007507 |
GO:1901226 | obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development | consider GO:0007507 |
GO:1905066 | obsolete regulation of canonical Wnt signaling pathway involved in heart development | consider GO:0007507 |
GO:1905067 | obsolete negative regulation of canonical Wnt signaling pathway involved in heart development | consider GO:0007507 |
GO:1905068 | obsolete positive regulation of canonical Wnt signaling pathway involved in heart development | consider GO:0007507 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0007507 based on ALL annotations
The top 100 of 6,241 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
heart development
|
2,735.33 | 100.00 | 71,267 | 71,267 |
muscle alpha-actinin binding
|
1,837.34 | 15.29 | 11,773 | 17,527 |
filamentous actin
|
1,873.92 | 15.17 | 11,621 | 16,963 |
muscle structure development
|
1,735.01 | 15.05 | 11,744 | 18,515 |
stress fiber
|
630.77 | 10.59 | 11,671 | 50,611 |
Z disc
|
461.61 | 9.23 | 12,058 | 71,452 |
cellular response to growth factor stimulus
|
630.78 | 6.74 | 6,192 | 26,851 |
adherens junction
|
253.38 | 6.51 | 12,810 | 138,289 |
cell surface receptor protein serine/threonine kinase signaling pathway
|
627.44 | 6.30 | 5,691 | 24,810 |
determination of left/right symmetry
|
1,103.87 | 6.03 | 4,718 | 11,691 |
Totals | 460823 | 5983971 |
No co-occurrence statistics for GO:0007507 based on MANUAL annotations
The top 100 of 5,783 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
heart development
|
517.76 | 100.00 | 2,495 | 2,495 |
determination of left/right symmetry
|
202.26 | 8.18 | 234 | 599 |
blood vessel development
|
202.86 | 7.16 | 201 | 513 |
heart morphogenesis
|
181.08 | 7.16 | 206 | 589 |
transforming growth factor beta receptor signaling pathway
|
113.21 | 6.49 | 211 | 965 |
muscle alpha-actinin binding
|
318.16 | 6.20 | 161 | 262 |
muscle structure development
|
318.14 | 5.91 | 153 | 249 |
cardiac epithelial to mesenchymal transition
|
371.59 | 5.87 | 150 | 209 |
positive regulation of gene expression
|
48.31 | 5.61 | 308 | 3,301 |
vasculogenesis
|
162.25 | 5.53 | 157 | 501 |
Totals | 14916 | 127277 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2020-02-28 | Deleted | XREF | MIPS_funcat:47.03.03.01 |
2019-05-04 | Added | XREF | MIPS_funcat:47.03.03.01 |
2017-08-13 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2016-09-17 | Added | RELATION | part of GO:0072359 (circulatory system development) |
2016-09-17 | Deleted | RELATION | part of GO:0072358 (cardiovascular system development) |
2012-12-23 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2010-11-18 | Added | RELATION | part of GO:0072358 (cardiovascular system development) |
2009-03-02 | Added | XREF | Wikipedia:Heart_development |
2008-05-13 | Added | DEFINITION | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | heart development |
2001-04-03 | Updated | TERM | heart development |
2001-03-30 | Added | TERM | heart development |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
2008-05-12 | Deleted | DEFINITION | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
2007-08-09 | Deleted | SYNONYM | dorsal vessel development |
2007-08-09 | Added | SYNONYM | dorsal vessel development |
2007-08-09 | Added | SYNONYM | cardiac development |
2007-08-09 | Deleted | SYNONYM | cardiac development |
2007-03-11 | Added | SYNONYM | cardiac development |
2005-07-06 | Updated | DEFINITION | The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
2005-05-27 | Updated | DEFINITION | The process aimed at the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
2004-07-18 | Updated | DEFINITION | Processes aimed at the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
2003-10-22 | Added | SYNONYM | dorsal vessel development |
2003-07-04 | Added | DEFINITION | Development of the heart; a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-13 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2016-09-17 | Added | RELATION | part of GO:0072359 (circulatory system development) |
2016-09-17 | Deleted | RELATION | part of GO:0072358 (cardiovascular system development) |
2012-12-23 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2010-11-18 | Added | RELATION | part of GO:0072358 (cardiovascular system development) |
2008-04-01 | Updated | RELATION | is a GO:0048513 (animal organ development) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:47.03.03.01 |
2019-05-04 | Added | XREF | MIPS_funcat:47.03.03.01 |
2009-03-02 | Added | XREF | Wikipedia:Heart_development |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2003-10-22 | Added | SECONDARY | GO:0007511 (dorsal vessel development) |
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