This term is obsolete.

GO:0007507 JSON

heart development

Biological Process

Definition (GO:0007507 GONUTS page)

The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

Secondary IDs

GO:0007511

229,977 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
dorsal vessel development narrow
cardiac development related

Ancestor Chart

Ancestor chart for GO:0007507
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0007507

Child Term Relationship to
GO:0007507
heart growth
part_of
cardiac jelly development
part_of
endocardium development
part_of
larval heart development
is_a
heart valve development
part_of
heart morphogenesis
part_of
cell surface receptor signaling pathway involved in heart development
part_of
fibroblast growth factor receptor signaling pathway involved in heart development
part_of
cardiac muscle tissue development
part_of
atrioventricular canal development
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0007507 heart development Only in Taxon 33213 Bilateria

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1D5NZN4 9031 A0A1D5NZN4_CHICK GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:17549728
NOT-qualified manual protein F7FNP9 10116 F7FNP9_RAT GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P43680 10090 SOX18_MOUSE GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11094083
NOT-qualified manual protein Q4V7E4 10116 Q4V7E4_RAT GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR000482 5-Hydroxytryptamine 2B receptor
InterPro IPR002261 Gap junction alpha-1 protein (Cx43)
InterPro IPR037885 Heat shock protein beta-7, ACD domain
InterPro IPR047853 Apelin receptor early endogenous ligand
Wikipedia Heart_development

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0061310 obsolete canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development consider GO:0007507
GO:0061312 obsolete BMP signaling pathway involved in heart development consider GO:0007507
GO:1901225 obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development consider GO:0007507
GO:1901226 obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development consider GO:0007507
GO:1905066 obsolete regulation of canonical Wnt signaling pathway involved in heart development consider GO:0007507
GO:1905067 obsolete negative regulation of canonical Wnt signaling pathway involved in heart development consider GO:0007507
GO:1905068 obsolete positive regulation of canonical Wnt signaling pathway involved in heart development consider GO:0007507

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0007507 based on ALL annotations
The top 100 of 6,241 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heart development
2,735.33 100.00 71,267 71,267
muscle alpha-actinin binding
1,837.34 15.29 11,773 17,527
filamentous actin
1,873.92 15.17 11,621 16,963
muscle structure development
1,735.01 15.05 11,744 18,515
stress fiber
630.77 10.59 11,671 50,611
Z disc
461.61 9.23 12,058 71,452
cellular response to growth factor stimulus
630.78 6.74 6,192 26,851
adherens junction
253.38 6.51 12,810 138,289
cell surface receptor protein serine/threonine kinase signaling pathway
627.44 6.30 5,691 24,810
determination of left/right symmetry
1,103.87 6.03 4,718 11,691
Totals 460823 5983971
No co-occurrence statistics for GO:0007507 based on MANUAL annotations
The top 100 of 5,783 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heart development
517.76 100.00 2,495 2,495
determination of left/right symmetry
202.26 8.18 234 599
blood vessel development
202.86 7.16 201 513
heart morphogenesis
181.08 7.16 206 589
transforming growth factor beta receptor signaling pathway
113.21 6.49 211 965
muscle alpha-actinin binding
318.16 6.20 161 262
muscle structure development
318.14 5.91 153 249
cardiac epithelial to mesenchymal transition
371.59 5.87 150 209
positive regulation of gene expression
48.31 5.61 308 3,301
vasculogenesis
162.25 5.53 157 501
Totals 14916 127277

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
2020-02-28 Deleted XREF MIPS_funcat:47.03.03.01
2019-05-04 Added XREF MIPS_funcat:47.03.03.01
2017-08-13 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2016-09-17 Added RELATION part of GO:0072359 (circulatory system development)
2016-09-17 Deleted RELATION part of GO:0072358 (cardiovascular system development)
2012-12-23 Added RELATION is a GO:0044767 (single-organism developmental process)
2010-11-18 Added RELATION part of GO:0072358 (cardiovascular system development)
2009-03-02 Added XREF Wikipedia:Heart_development
2008-05-13 Added DEFINITION The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
Timestamp Action Category Detail
2002-02-06 Updated TERM heart development
2001-04-03 Updated TERM heart development
2001-03-30 Added TERM heart development
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2008-05-12 Deleted DEFINITION The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2007-08-09 Deleted SYNONYM dorsal vessel development
2007-08-09 Added SYNONYM dorsal vessel development
2007-08-09 Added SYNONYM cardiac development
2007-08-09 Deleted SYNONYM cardiac development
2007-03-11 Added SYNONYM cardiac development
2005-07-06 Updated DEFINITION The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2005-05-27 Updated DEFINITION The process aimed at the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2004-07-18 Updated DEFINITION Processes aimed at the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2003-10-22 Added SYNONYM dorsal vessel development
2003-07-04 Added DEFINITION Development of the heart; a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
Timestamp Action Category Detail
2017-08-13 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2016-09-17 Added RELATION part of GO:0072359 (circulatory system development)
2016-09-17 Deleted RELATION part of GO:0072358 (cardiovascular system development)
2012-12-23 Added RELATION is a GO:0044767 (single-organism developmental process)
2010-11-18 Added RELATION part of GO:0072358 (cardiovascular system development)
2008-04-01 Updated RELATION is a GO:0048513 (animal organ development)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:47.03.03.01
2019-05-04 Added XREF MIPS_funcat:47.03.03.01
2009-03-02 Added XREF Wikipedia:Heart_development
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
2003-10-22 Added SECONDARY GO:0007511 (dorsal vessel development)
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