This term is obsolete.

GO:0008017 JSON

microtubule binding

Molecular Function

Definition (GO:0008017 GONUTS page)

Binding to a microtubule, a filament composed of tubulin monomers.

486,888 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
microtubule severing activity related
microtubule/chromatin interaction related

Ancestor Chart

Ancestor chart for GO:0008017
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008017

Child Term Relationship to
GO:0008017
S100A9 complex
capable_of
negative regulation of microtubule binding
negatively_regulates
positive regulation of microtubule binding
positively_regulates
microtubule lateral binding
is_a
regulation of microtubule binding
regulates
microtubule minus-end binding
is_a
microtubule plus-end binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q00535 9606 CDK5_HUMAN GO:0008017 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17491008
NOT-qualified manual protein Q2HIK4 3702 PFD6_ARATH GO:0008017 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19004800
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Cross-references

Database ID Description
InterPro IPR001265 Formin homology family, Cappuccino subfamily
InterPro IPR001752 Kinesin motor domain
InterPro IPR002955 Microtubule-associated protein Tau
InterPro IPR003108 GAR domain
InterPro IPR004953 EB1, C-terminal
InterPro IPR007145 Microtubule-associated protein, MAP65/Ase1/PRC1
InterPro IPR007882 Microtubule-associated protein 6
InterPro IPR008636 Hook, C-terminal
InterPro IPR009234 Adenomatous polyposis coli protein basic domain
InterPro IPR009768 Microtubule-associated protein 70

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0008351 obsolete microtubule severing activity consider GO:0008017
GO:0008546 obsolete microtubule/chromatin interaction consider GO:0008017

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008017 based on ALL annotations
The top 100 of 5,088 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microtubule binding
453.67 100.00 429,694 429,694
microtubule
208.84 33.92 241,981 525,653
microtubule motor activity
446.43 33.70 145,621 147,982
microtubule-based movement
267.67 27.43 145,638 246,841
cytoskeletal motor activity
156.51 18.65 124,077 359,662
cytoskeleton
74.31 13.78 199,552 1,218,329
microtubule cytoskeleton organization
161.62 10.14 53,342 149,732
microtubule cytoskeleton
172.36 7.88 38,842 102,238
spindle
147.59 7.83 40,167 123,469
spindle elongation
429.45 7.70 33,251 35,126
Totals 2547942 15863400
No co-occurrence statistics for GO:0008017 based on MANUAL annotations
The top 100 of 3,133 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microtubule binding
150.82 100.00 8,565 8,565
microtubule
89.31 30.94 3,367 5,686
kinesin complex
149.04 25.28 2,172 2,198
microtubule-based movement
108.47 19.40 1,798 2,500
microtubule motor activity
112.75 16.31 1,478 1,977
ATP hydrolysis activity
31.51 12.77 2,118 10,138
microtubule cytoskeleton organization
39.78 10.58 1,286 4,876
plus-end-directed microtubule motor activity
107.52 8.08 715 1,003
microtubule cytoskeleton
39.89 7.00 744 2,813
cytoplasmic microtubule
74.27 6.74 620 1,259
Totals 46645 454844

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2021-05-24 Added DEFINITION Binding to a microtubule, a filament composed of tubulin monomers.
2020-07-19 Added XREF Reactome:R-HSA-9614343
2016-06-22 Deleted RELATION is a GO:0032403 (protein complex binding)
2016-02-04 Added RELATION has part GO:0008608 (attachment of spindle microtubules to kinetochore)
2013-09-27 Added RELATION is a GO:0032403 (protein complex binding)
2009-07-03 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2008-05-13 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-12 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
Timestamp Action Category Detail
2003-06-10 Updated TERM microtubule binding
2003-03-19 Updated TERM microtubule binding activity
2002-02-06 Updated TERM microtubule binding
2001-04-03 Updated TERM microtubule binding
2001-03-30 Added TERM microtubule binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2021-05-24 Added DEFINITION Binding to a microtubule, a filament composed of tubulin monomers.
2009-07-03 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2008-05-13 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-12 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2007-08-09 Deleted SYNONYM microtubule severing activity
2007-08-09 Added SYNONYM microtubule/chromatin interaction
2007-08-09 Added SYNONYM microtubule severing activity
2007-08-09 Deleted SYNONYM microtubule/chromatin interaction
2005-08-10 Added SYNONYM microtubule/chromatin interaction
2005-08-10 Added SYNONYM microtubule severing activity
2003-03-26 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
Timestamp Action Category Detail
2016-06-22 Deleted RELATION is a GO:0032403 (protein complex binding)
2016-02-04 Added RELATION has part GO:0008608 (attachment of spindle microtubules to kinetochore)
2013-09-27 Added RELATION is a GO:0032403 (protein complex binding)
2008-04-01 Updated RELATION is a GO:0015631 (tubulin binding)
Timestamp Action Category Detail
2020-07-19 Added XREF Reactome:R-HSA-9614343
Timestamp Action Category Detail
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.