This term is obsolete.

GO:0008017 JSON

microtubule binding

Molecular Function

Definition (GO:0008017 GONUTS page)

Binding to a microtubule, a filament composed of tubulin monomers.

507,216 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
microtubule severing activity related
microtubule/chromatin interaction related

Ancestor Chart

Ancestor chart for GO:0008017
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008017

Child Term Relationship to
GO:0008017
S100A9 complex
capable_of
negative regulation of microtubule binding
negatively_regulates
microtubule plus-end binding
is_a
regulation of microtubule binding
regulates
microtubule lateral binding
is_a
microtubule minus-end binding
is_a
positive regulation of microtubule binding
positively_regulates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q00535 9606 CDK5_HUMAN GO:0008017 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17491008
NOT-qualified manual protein Q2HIK4 3702 PFD6_ARATH GO:0008017 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19004800
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Cross-references

Database ID Description
InterPro IPR001265 Formin homology family, Cappuccino subfamily
InterPro IPR001752 Kinesin motor domain
InterPro IPR002955 Microtubule-associated protein Tau
InterPro IPR003108 GAR domain
InterPro IPR004953 EB1, C-terminal
InterPro IPR007145 Microtubule-associated protein, MAP65/Ase1/PRC1
InterPro IPR007882 Microtubule-associated protein 6
InterPro IPR008636 Hook, C-terminal
InterPro IPR009234 Adenomatous polyposis coli protein basic domain
InterPro IPR009768 Microtubule-associated protein 70

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0008351 obsolete microtubule severing activity consider GO:0008017
GO:0008546 obsolete microtubule/chromatin interaction consider GO:0008017

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008017 based on ALL annotations
The top 100 of 5,058 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microtubule binding
442.89 100.00 447,415 447,415
microtubule
207.36 34.41 252,768 539,869
microtubule motor activity
435.84 33.82 152,126 154,587
microtubule-based movement
262.47 27.56 152,147 256,727
cytoskeletal motor activity
155.20 18.86 129,736 370,213
cytoskeleton
77.62 14.46 202,457 1,155,248
microtubule cytoskeleton organization
163.08 10.60 57,964 157,421
spindle
157.17 8.50 44,963 126,700
microtubule cytoskeleton
166.19 8.10 41,893 111,643
spindle elongation
419.68 7.74 34,788 36,712
Totals 2637302 15480911
No co-occurrence statistics for GO:0008017 based on MANUAL annotations
The top 100 of 3,080 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microtubule binding
152.52 100.00 9,255 9,255
microtubule
90.16 29.82 3,477 5,882
kinesin complex
150.74 23.76 2,205 2,231
microtubule-based movement
108.35 18.75 1,879 2,645
microtubule motor activity
113.95 16.63 1,631 2,183
ATP hydrolysis activity
30.25 11.95 2,141 10,796
microtubule cytoskeleton organization
41.35 10.78 1,404 5,179
microtubule cytoskeleton
45.21 8.68 1,012 3,414
microtubule-based process
101.37 6.96 668 1,005
cytoplasmic microtubule
75.75 6.73 668 1,345
Totals 49726 489080

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2021-05-24 Added DEFINITION Binding to a microtubule, a filament composed of tubulin monomers.
2020-07-19 Added XREF Reactome:R-HSA-9614343
2016-06-22 Deleted RELATION is a GO:0032403 (protein complex binding)
2016-02-04 Added RELATION has part GO:0008608 (attachment of spindle microtubules to kinetochore)
2013-09-27 Added RELATION is a GO:0032403 (protein complex binding)
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2009-07-03 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-13 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-12 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
Timestamp Action Category Detail
2003-06-10 Updated TERM microtubule binding
2003-03-19 Updated TERM microtubule binding activity
2002-02-06 Updated TERM microtubule binding
2001-04-03 Updated TERM microtubule binding
2001-03-30 Added TERM microtubule binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2021-05-24 Added DEFINITION Binding to a microtubule, a filament composed of tubulin monomers.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2009-07-03 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-13 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2008-05-12 Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2007-08-09 Deleted SYNONYM microtubule severing activity
2007-08-09 Added SYNONYM microtubule/chromatin interaction
2007-08-09 Added SYNONYM microtubule severing activity
2007-08-09 Deleted SYNONYM microtubule/chromatin interaction
2005-08-10 Added SYNONYM microtubule/chromatin interaction
2005-08-10 Added SYNONYM microtubule severing activity
2003-03-26 Added DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
Timestamp Action Category Detail
2016-06-22 Deleted RELATION is a GO:0032403 (protein complex binding)
2016-02-04 Added RELATION has part GO:0008608 (attachment of spindle microtubules to kinetochore)
2013-09-27 Added RELATION is a GO:0032403 (protein complex binding)
2008-04-01 Updated RELATION is a GO:0015631 (tubulin binding)
Timestamp Action Category Detail
2020-07-19 Added XREF Reactome:R-HSA-9614343
Timestamp Action Category Detail
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