GO:0008441
JSON
3'(2'),5'-bisphosphate nucleotidase activity
Molecular Function
Definition (GO:0008441 GONUTS page)
Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
DPNPase activity | related |
adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity | related |
phosphoadenylate 3'-nucleotidase activity | related |
3'-phosphoadenylylsulfate 3'-phosphatase activity | related |
3'(2'),5' bisphosphate nucleotidase activity | exact |
3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | A0A087QTQ7 | 9233 | A0A087QTQ7_APTFO | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A087VMI5 | 100784 | A0A087VMI5_BALRE | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091CMN8 | 885580 | A0A091CMN8_FUKDA | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091HHI2 | 9244 | A0A091HHI2_CALAN | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091JLW6 | 188379 | A0A091JLW6_EGRGA | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091L9X5 | 187382 | A0A091L9X5_9AVES | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091P439 | 57397 | A0A091P439_APAVI | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091SAD7 | 54374 | A0A091SAD7_9AVES | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A091SQ34 | 176057 | A0A091SQ34_NESNO | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
IEA Review | protein | A0A093DPA0 | 121530 | A0A093DPA0_TAUER | GO:0016791 | To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. | IPR000387|IPR016130 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.1.3.7 | |
InterPro | IPR006239 | 3(2),5 -bisphosphate nucleotidase |
InterPro | IPR006240 | 3'(2'),5'-bisphosphate nucleotidase CysQ |
MetaCyc | 325-BISPHOSPHATE-NUCLEOTIDASE-RXN | |
RHEA | 10040 | |
Reactome | R-HSA-176606 | |
Reactome | R-HSA-8953499 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:456215 | adenosine 5'-monophosphate(2-) |
has_participant | CHEBI | CHEBI:58343 | adenosine 3',5'-bismonophosphate(4-) |
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:43474 | hydrogenphosphate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008441 based on ALL annotations
The top 100 of 230 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3'(2'),5'-bisphosphate nucleotidase activity
|
7,534.74 | 100.00 | 25,872 | 25,872 |
3'-phosphoadenosine 5'-phosphosulfate metabolic process
|
7,338.88 | 65.60 | 17,274 | 17,735 |
sulfate assimilation
|
1,412.48 | 18.38 | 23,373 | 124,681 |
sulfur compound metabolic process
|
1,141.28 | 13.97 | 16,618 | 109,712 |
phosphatidylinositol phosphate biosynthetic process
|
690.66 | 8.53 | 14,212 | 155,046 |
inositol phosphate metabolic process
|
6,691.36 | 6.45 | 1,682 | 1,894 |
inositol-1,4-bisphosphate 1-phosphatase activity
|
1,312.61 | 0.86 | 231 | 1,326 |
inositol-1,3,4-trisphosphate 1-phosphatase activity
|
7,422.28 | 0.77 | 198 | 201 |
tRNA decay
|
3,972.12 | 0.74 | 194 | 368 |
hyperosmotic salinity response
|
1,611.62 | 0.73 | 194 | 907 |
Totals | 180440 | 72894726 |
No co-occurrence statistics for GO:0008441 based on MANUAL annotations
The top 31 of 31 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3'(2'),5'-bisphosphate nucleotidase activity
|
4,911.78 | 100.00 | 263 | 263 |
sulfate assimilation
|
1,683.83 | 32.62 | 229 | 668 |
3'-phosphoadenosine 5'-phosphosulfate metabolic process
|
2,210.30 | 6.32 | 18 | 40 |
inositol-1,4-bisphosphate 1-phosphatase activity
|
633.78 | 1.38 | 4 | 31 |
inositol bisphosphate phosphatase activity
|
218.30 | 0.65 | 2 | 45 |
rapid tRNA decay
|
2,455.89 | 0.38 | 1 | 2 |
inositol monophosphate 1-phosphatase activity
|
36.66 | 0.38 | 2 | 268 |
inositol-1,3,4-trisphosphate 1-phosphatase activity
|
1,227.95 | 0.38 | 1 | 4 |
regulation of neuronal signal transduction
|
818.63 | 0.37 | 1 | 6 |
dauer exit
|
409.32 | 0.36 | 1 | 12 |
Totals | 558 | 894711 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | phosphoadenylate 3'-nucleotidase activity |
2020-10-08 | Deleted | SYNONYM | DPNPase activity |
2020-10-08 | Deleted | SYNONYM | 3'-phosphoadenylylsulfate 3'-phosphatase activity |
2020-10-08 | Added | SYNONYM | 3'-phosphoadenylylsulfate 3'-phosphatase activity |
2020-10-08 | Added | SYNONYM | phosphoadenylate 3'-nucleotidase activity |
2020-10-08 | Added | SYNONYM | DPNPase activity |
2020-10-08 | Added | SYNONYM | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity |
2020-10-08 | Added | SYNONYM | 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | 3'(2'),5'-bisphosphate nucleotidase activity |
2002-02-06 | Updated | TERM | 3'(2'),5'-bisphosphate nucleotidase |
2001-04-03 | Updated | TERM | 3'(2'),5'-bisphosphate nucleotidase |
2001-03-30 | Added | TERM | 3'(2'),5'-bisphosphate nucleotidase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | phosphoadenylate 3'-nucleotidase activity |
2020-10-08 | Deleted | SYNONYM | DPNPase activity |
2020-10-08 | Deleted | SYNONYM | 3'-phosphoadenylylsulfate 3'-phosphatase activity |
2020-10-08 | Added | SYNONYM | 3'-phosphoadenylylsulfate 3'-phosphatase activity |
2020-10-08 | Added | SYNONYM | phosphoadenylate 3'-nucleotidase activity |
2020-10-08 | Added | SYNONYM | DPNPase activity |
2020-10-08 | Added | SYNONYM | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity |
2020-10-08 | Added | SYNONYM | 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. |
2007-11-08 | Added | SYNONYM | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity |
2007-09-06 | Added | SYNONYM | phosphoadenylate 3'-nucleotidase activity |
2007-09-06 | Added | SYNONYM | 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity |
2007-09-06 | Added | SYNONYM | DPNPase activity |
2007-09-06 | Added | SYNONYM | 3'-phosphoadenylylsulfate 3'-phosphatase activity |
2007-08-09 | Deleted | SYNONYM | 3'(2'),5' bisphosphate nucleotidase activity |
2007-08-09 | Added | SYNONYM | 3'(2'),5' bisphosphate nucleotidase activity |
2004-04-19 | Added | SYNONYM | 3'(2'),5' bisphosphate nucleotidase activity |
2004-04-16 | Deleted | SYNONYM | 3'(2'),5' bisphosphate nucleotidase activity |
2004-02-26 | Added | SYNONYM | 3'(2'),5' bisphosphate nucleotidase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008252 (nucleotidase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Added | XREF | Reactome:R-HSA-8953499 |
2019-04-01 | Added | XREF | Reactome:R-HSA-176606 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-8953499 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-176606 |
2018-12-11 | Added | XREF | reactome:R-HSA-8953499 |
2018-12-11 | Added | XREF | reactome:R-HSA-176606 |
2018-07-13 | Deleted | XREF | RHEA:10043 |
2018-07-13 | Added | XREF | RHEA:10040 |
2011-09-16 | Added | XREF | RHEA:10043 |
2009-05-21 | Deleted | XREF | MetaCyc:3'(2'),5'-BISPHOSPHATE-NUCLEOTIDASE-RXN |
2009-05-21 | Added | XREF | MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN |
2003-10-27 | Added | XREF | MetaCyc:3'(2'),5'-BISPHOSPHATE-NUCLEOTIDASE-RXN |
2001-03-30 | Added | XREF | EC:3.1.3.7 |
Timestamp | Action | Category | Detail |
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