GO:0008658
JSON
penicillin binding
Molecular Function
Definition (GO:0008658 GONUTS page)
Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Ancestor Chart
Ancestor chart for GO:0008658
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001460 | Penicillin-binding protein, transpeptidase |
InterPro | IPR005311 | Penicillin-binding protein, dimerisation domain |
InterPro | IPR017790 | Penicillin-binding protein 2 |
InterPro | IPR036138 | Penicillin-binding protein, dimerisation domain superfamily |
InterPro | IPR037532 | Peptidoglycan D,D-transpeptidase FtsI |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:51356 | penicillinate anion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008658 based on ALL annotations
The top 100 of 360 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
penicillin binding
|
866.55 | 100.00 | 228,670 | 228,670 |
peptidoglycan glycosyltransferase activity
|
600.20 | 39.29 | 108,809 | 157,097 |
serine-type D-Ala-D-Ala carboxypeptidase activity
|
393.56 | 21.62 | 66,808 | 147,100 |
peptidoglycan L,D-transpeptidase activity
|
379.72 | 20.53 | 63,735 | 145,447 |
carboxypeptidase activity
|
206.84 | 20.20 | 129,932 | 544,350 |
peptidoglycan biosynthetic process
|
112.31 | 12.13 | 149,404 | 1,152,754 |
cell wall organization
|
103.49 | 11.52 | 174,920 | 1,464,669 |
outer membrane-bounded periplasmic space
|
92.99 | 9.35 | 96,331 | 897,720 |
regulation of cell shape
|
71.53 | 7.47 | 100,702 | 1,219,943 |
response to antibiotic
|
89.75 | 7.07 | 41,699 | 402,608 |
Totals | 1781477 | 178249954 |
No co-occurrence statistics for GO:0008658 based on MANUAL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
penicillin binding
|
12,949.85 | 100.00 | 109 | 109 |
peptidoglycan L,D-transpeptidase activity
|
5,326.15 | 28.02 | 51 | 124 |
cell wall organization
|
1,755.30 | 13.35 | 98 | 723 |
serine-type D-Ala-D-Ala carboxypeptidase activity
|
8,633.23 | 7.08 | 8 | 12 |
peptidoglycan glycosyltransferase activity
|
754.36 | 2.91 | 6 | 103 |
peptidoglycan biosynthetic process
|
380.88 | 2.14 | 8 | 272 |
peptidoglycan metabolic process
|
289.92 | 1.25 | 3 | 134 |
beta-lactamase activity
|
304.70 | 1.04 | 2 | 85 |
carboxypeptidase activity
|
166.45 | 1.01 | 5 | 389 |
positive regulation of bipolar cell growth
|
12,949.84 | 0.92 | 1 | 1 |
Totals | 449 | 369169 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_metagenomics | 111 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Deleted | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2022-12-24 | Deleted | RELATION | is a GO:0043177 (organic acid binding) |
2021-07-10 | Deleted | RELATION | is a GO:0008144 (obsolete drug binding) |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2021-05-24 | Added | DEFINITION | Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2020-11-03 | Added | RELATION | is a GO:0043177 (organic acid binding) |
2016-11-28 | Added | RELATION | is a GO:0033293 (monocarboxylic acid binding) |
2016-11-28 | Deleted | RELATION | is a GO:0043177 (organic acid binding) |
2016-07-23 | Added | SUBSET | goslim_metagenomics |
2016-06-22 | Added | RELATION | is a GO:0043177 (organic acid binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | penicillin binding |
2003-03-19 | Updated | TERM | penicillin binding activity |
2002-02-06 | Updated | TERM | penicillin binding |
2001-04-03 | Updated | TERM | penicillin binding |
2001-03-30 | Added | TERM | penicillin binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2021-05-24 | Added | DEFINITION | Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2008-05-13 | Added | DEFINITION | Interacting selectively with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2003-03-26 | Updated | DEFINITION | Interacting selectively with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-23 | Deleted | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2022-12-24 | Deleted | RELATION | is a GO:0043177 (organic acid binding) |
2021-07-10 | Deleted | RELATION | is a GO:0008144 (obsolete drug binding) |
2020-11-03 | Added | RELATION | is a GO:0043177 (organic acid binding) |
2016-11-28 | Added | RELATION | is a GO:0033293 (monocarboxylic acid binding) |
2016-11-28 | Deleted | RELATION | is a GO:0043177 (organic acid binding) |
2016-06-22 | Added | RELATION | is a GO:0043177 (organic acid binding) |
2016-06-22 | Deleted | RELATION | is a GO:0033293 (monocarboxylic acid binding) |
2012-12-05 | Added | RELATION | is a GO:1901681 (sulfur compound binding) |
2012-11-15 | Added | RELATION | is a GO:0033293 (monocarboxylic acid binding) |
2012-11-15 | Deleted | RELATION | is a GO:0031406 (carboxylic acid binding) |
2012-09-19 | Added | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2012-09-19 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2012-09-19 | Added | RELATION | is a GO:0033218 (amide binding) |
2009-07-03 | Added | RELATION | is a GO:0031406 (carboxylic acid binding) |
2008-04-01 | Updated | RELATION | is a GO:0008144 (obsolete drug binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-07-23 | Added | SUBSET | goslim_metagenomics |
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