GO:0009966
JSON
regulation of signal transduction
Biological Process
Definition (GO:0009966 GONUTS page)
Any process that modulates the frequency, rate or extent of signal transduction.
Secondary IDs
GO:0035466
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| regulation of signalling pathway | related |
| regulation of signaling pathway | related |
Ancestor Chart
Ancestor chart for GO:0009966
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0009966
| Child Term | Relationship to GO:0009966 |
|---|---|
|
regulation of lipopolysaccharide-mediated signaling pathway
|
is_a |
|
regulation of insulin-like growth factor receptor signaling pathway
|
is_a |
|
regulation of hepatocyte growth factor receptor signaling pathway
|
is_a |
|
regulation of integrin-mediated signaling pathway
|
is_a |
|
modulation of inhibitory postsynaptic potential
|
is_a |
|
regulation of postsynapse to nucleus signaling pathway
|
is_a |
|
regulation of insulin receptor signaling pathway
|
is_a |
|
signal complex assembly
|
is_a |
|
regulation of cytokinin-activated signaling pathway
|
is_a |
|
regulation of salicylic acid mediated signaling pathway
|
is_a |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
| Ontology Development Project | |
|---|---|
| signalling | Link |
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR000693 | Sea anemone toxin |
| InterPro | IPR001863 | Glypican |
| InterPro | IPR007062 | Protein phosphatase inhibitor 2 (IPP-2) |
| InterPro | IPR007304 | TAP46-like protein |
| InterPro | IPR007875 | Sprouty |
| InterPro | IPR008131 | Early E3 14.5kDa protein |
| InterPro | IPR010599 | Connector enhancer of kinase suppressor of ras 2/3 domain |
| InterPro | IPR016253 | Integrin-linked kinase |
| InterPro | IPR016574 | Nicalin |
| InterPro | IPR042651 | Regulator of G-protein signaling 22 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0009966 based on ALL annotations
The top 100 of 2,550 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
regulation of signal transduction
|
2,443.37 | 100.00 | 81,099 | 81,099 |
|
G protein-coupled receptor kinase activity
|
2,140.06 | 16.00 | 13,279 | 15,161 |
|
regulation of protein localization to membrane
|
2,438.38 | 9.03 | 7,323 | 7,338 |
|
basal plasma membrane
|
955.36 | 5.55 | 4,927 | 12,601 |
|
ERBB signaling pathway
|
1,862.03 | 5.41 | 4,465 | 5,859 |
|
collagen-containing extracellular matrix
|
193.42 | 5.30 | 11,202 | 141,510 |
|
regulation of dephosphorylation
|
1,436.69 | 4.98 | 4,183 | 7,114 |
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
1,161.55 | 4.96 | 4,259 | 8,959 |
|
protein phosphatase 2A binding
|
844.71 | 4.84 | 4,319 | 12,493 |
|
G protein-coupled receptor binding
|
243.61 | 4.74 | 6,732 | 67,521 |
| Totals | 428083 | 12215894 | ||
No co-occurrence statistics for GO:0009966 based on MANUAL annotations
The top 100 of 1,040 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
regulation of signal transduction
|
855.47 | 100.00 | 1,650 | 1,650 |
|
protein phosphatase regulator activity
|
171.21 | 10.30 | 289 | 1,444 |
|
calcium sensitive guanylate cyclase activator activity
|
839.63 | 6.42 | 106 | 108 |
|
calcium ion binding
|
56.45 | 5.87 | 572 | 8,668 |
|
regulation of potassium ion transmembrane transport
|
260.89 | 4.66 | 86 | 282 |
|
FAR/SIN/STRIPAK complex
|
245.28 | 4.42 | 82 | 286 |
|
K63-linked deubiquitinase activity
|
219.35 | 4.25 | 80 | 312 |
|
potassium channel regulator activity
|
84.95 | 3.54 | 86 | 866 |
|
G protein-coupled receptor kinase activity
|
541.44 | 2.98 | 50 | 79 |
|
cone photoreceptor outer segment
|
543.34 | 2.80 | 47 | 74 |
| Totals | 4747 | 134673 | ||
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2012-10-29 | Added | RELATION | is a GO:0010646 (regulation of cell communication) |
| 2012-10-29 | Deleted | RELATION | is a GO:0050794 (regulation of cellular process) |
| 2011-01-30 | Deleted | RELATION | is a GO:0050789 (regulation of biological process) |
| 2011-01-30 | Added | RELATION | is a GO:0050794 (regulation of cellular process) |
| 2011-01-30 | Added | RELATION | is a GO:0048583 (regulation of response to stimulus) |
| 2011-01-16 | Added | SYNONYM | regulation of signaling pathway |
| 2011-01-16 | Added | RELATION | is a GO:0050789 (regulation of biological process) |
| 2011-01-16 | Added | SECONDARY | GO:0035466 (regulation of signaling pathway) |
| 2011-01-16 | Added | SYNONYM | regulation of signalling pathway |
| 2010-10-28 | Deleted | RELATION | is a GO:0010646 (regulation of cell communication) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2002-12-18 | Added | TERM | regulation of signal transduction |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-01-16 | Added | SYNONYM | regulation of signaling pathway |
| 2011-01-16 | Added | SYNONYM | regulation of signalling pathway |
| 2008-05-13 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of signal transduction. |
| 2008-05-12 | Deleted | DEFINITION | Any process that modulates the frequency, rate or extent of signal transduction. |
| 2003-03-26 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of signal transduction. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2012-10-29 | Added | RELATION | is a GO:0010646 (regulation of cell communication) |
| 2012-10-29 | Deleted | RELATION | is a GO:0050794 (regulation of cellular process) |
| 2011-01-30 | Deleted | RELATION | is a GO:0050789 (regulation of biological process) |
| 2011-01-30 | Added | RELATION | is a GO:0050794 (regulation of cellular process) |
| 2011-01-30 | Added | RELATION | is a GO:0048583 (regulation of response to stimulus) |
| 2011-01-16 | Added | RELATION | is a GO:0050789 (regulation of biological process) |
| 2010-10-28 | Deleted | RELATION | is a GO:0010646 (regulation of cell communication) |
| 2010-02-20 | Added | RELATION | is a GO:0023051 (regulation of signaling) |
| 2008-10-21 | Added | RELATION | is a GO:0010646 (regulation of cell communication) |
| 2008-10-21 | Deleted | RELATION | is a GO:0050794 (regulation of cellular process) |
| 2008-04-01 | Added | RELATION | regulates GO:0007165 (signal transduction) |
| 2008-04-01 | Updated | RELATION | part of GO:0007165 (signal transduction) |
| 2008-04-01 | Deleted | RELATION | part of GO:0007165 (signal transduction) |
| 2008-04-01 | Updated | RELATION | is a GO:0050794 (regulation of cellular process) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-01-16 | Added | SECONDARY | GO:0035466 (regulation of signaling pathway) |
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