GO:0010917
JSON
negative regulation of mitochondrial membrane potential
Biological Process
Definition (GO:0010917 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| reduction of mitochondrial membrane potential | exact |
Ancestor Chart
Ancestor chart for GO:0010917
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | Q07813 | 10090 | BAX_MOUSE | GO:0051881 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:14614769 | |
| NOT-qualified manual | protein | Q63690 | 10116 | BAX_RAT | GO:0051881 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0010917 based on ALL annotations
The top 100 of 571 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of mitochondrial membrane potential
|
351,131.28 | 100.00 | 567 | 567 |
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
117,043.77 | 17.67 | 155 | 465 |
|
regulation of mitochondrial fusion
|
347,435.16 | 16.55 | 94 | 95 |
|
negative regulation of L-glutamate import across plasma membrane
|
333,216.40 | 16.26 | 93 | 98 |
|
cellular response to radiation
|
261,955.10 | 15.69 | 94 | 126 |
|
establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
|
178,412.66 | 14.29 | 94 | 185 |
|
release of matrix enzymes from mitochondria
|
320,786.60 | 12.89 | 74 | 81 |
|
BAX complex
|
302,136.22 | 12.78 | 74 | 86 |
|
positive regulation of apoptotic DNA fragmentation
|
167,533.23 | 11.28 | 73 | 153 |
|
BAK complex
|
155,348.98 | 11.08 | 73 | 165 |
| Totals | 7524 | 159704 | ||
No co-occurrence statistics for GO:0010917 based on MANUAL annotations
The top 100 of 531 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of mitochondrial membrane potential
|
23,912.05 | 100.00 | 59 | 59 |
|
regulation of mitochondrial fusion
|
16,554.50 | 14.29 | 9 | 13 |
|
establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
|
16,554.50 | 14.29 | 9 | 13 |
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
8,484.92 | 13.92 | 11 | 31 |
|
cellular response to radiation
|
10,760.42 | 12.86 | 9 | 20 |
|
negative regulation of mitochondrial calcium ion concentration
|
7,686.02 | 11.54 | 9 | 28 |
|
positive regulation of mitochondrial membrane permeability
|
13,948.70 | 10.94 | 7 | 12 |
|
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
|
6,148.81 | 10.59 | 9 | 35 |
|
regulation of protein targeting to mitochondrion
|
8,809.70 | 9.86 | 7 | 19 |
|
hematopoietic stem cell migration
|
5,124.01 | 9.78 | 9 | 42 |
| Totals | 564 | 5753 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-03-27 | Added | SYNONYM | reduction of mitochondrial membrane potential |
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| 2009-03-15 | Added | RELATION | is a GO:0045837 (negative regulation of membrane potential) |
| 2009-03-15 | Added | TERM | negative regulation of mitochondrial membrane potential |
| 2009-03-15 | Added | RELATION | is a GO:0051881 (regulation of mitochondrial membrane potential) |
| 2009-03-15 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-03-15 | Added | TERM | negative regulation of mitochondrial membrane potential |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-03-27 | Added | SYNONYM | reduction of mitochondrial membrane potential |
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| 2009-03-15 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-03-15 | Added | RELATION | is a GO:0045837 (negative regulation of membrane potential) |
| 2009-03-15 | Added | RELATION | is a GO:0051881 (regulation of mitochondrial membrane potential) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
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