GO:0015093
JSON
ferrous iron transmembrane transporter activity
Molecular Function
Definition (GO:0015093 GONUTS page)
Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
Secondary IDs
GO:0015639
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ferrous iron uptake transmembrane transporter activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0015093
Child Term | Relationship to GO:0015093 |
---|---|
high-affinity ferrous iron transmembrane transporter activity
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A2WLC1 | 39946 | CDT3_ORYSI | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6K7I4 | 10116 | A6K7I4_RAT | GO:0034220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7MB71 | 9913 | AT1B4_BOVIN | GO:0098662 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | B4YDY0 | 10090 | B4YDY0_MOUSE | GO:0006811 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921 | |
NOT-qualified manual | protein | B8B2D0 | 39946 | CDT1_ORYSI | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D4ABB2 | 10116 | D4ABB2_RAT | GO:0034220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q5VRD7 | 39947 | CDT3_ORYSJ | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867 | |
NOT-qualified manual | protein | Q5VSB5 | 39947 | CDT1_ORYSJ | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867 | |
NOT-qualified manual | protein | Q6R3K9 | 3702 | YSL2_ARATH | GO:0006826 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15753101 | |
NOT-qualified manual | protein | Q6ZG85 | 39947 | NRAT1_ORYSJ | GO:0005381 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20937890 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR003373 | Ferrous iron transport protein B |
InterPro | IPR011640 | Ferrous iron transport protein B, C-terminal |
MetaCyc | TRANS-RXN-8 | |
Reactome | R-HSA-1362417 | |
Reactome | R-HSA-442368 | |
Reactome | R-HSA-5655760 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:29033 | iron(2+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0015093 based on ALL annotations
The top 100 of 349 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferrous iron transmembrane transporter activity
|
2,369.31 | 100.00 | 83,634 | 83,634 |
iron ion transmembrane transport
|
1,134.27 | 46.14 | 77,542 | 161,973 |
iron ion transmembrane transporter activity
|
1,591.12 | 26.50 | 25,462 | 37,915 |
zinc efflux antiporter activity
|
2,369.31 | 25.66 | 21,463 | 21,463 |
high-affinity iron permease complex
|
1,991.24 | 20.68 | 18,002 | 21,420 |
intracellular zinc ion homeostasis
|
851.82 | 17.66 | 21,547 | 59,932 |
cadmium ion transmembrane transporter activity
|
552.49 | 14.26 | 22,456 | 96,300 |
cadmium ion transmembrane transport
|
549.87 | 14.22 | 22,456 | 96,760 |
zinc ion transmembrane transport
|
372.58 | 10.82 | 21,550 | 137,040 |
iron ion transport
|
277.81 | 10.51 | 42,109 | 359,124 |
Totals | 737427 | 131593639 |
No co-occurrence statistics for GO:0015093 based on MANUAL annotations
The top 100 of 162 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferrous iron transmembrane transporter activity
|
4,303.45 | 100.00 | 328 | 328 |
iron import into the mitochondrion
|
4,163.88 | 53.59 | 179 | 185 |
mitochondrial membrane
|
663.79 | 13.65 | 178 | 1,154 |
high-affinity iron permease complex
|
2,800.66 | 11.71 | 41 | 63 |
iron ion transmembrane transport
|
607.79 | 10.15 | 87 | 616 |
lead ion transmembrane transporter activity
|
4,098.53 | 6.08 | 20 | 21 |
zinc efflux antiporter activity
|
4,303.45 | 5.79 | 19 | 19 |
cobalt ion transmembrane transporter activity
|
1,031.04 | 5.74 | 23 | 96 |
cadmium ion binding
|
1,390.35 | 5.65 | 21 | 65 |
nickel cation transmembrane transporter activity
|
1,655.17 | 5.56 | 20 | 52 |
Totals | 1389 | 36071 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-14 | Deleted | XREF | RHEA:28486 |
2024-02-24 | Added | XREF | MetaCyc:TRANS-RXN-8 |
2020-12-17 | Deleted | RELATION | is a GO:0072509 (divalent inorganic cation transmembrane transporter activity) |
2019-05-04 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-01 | Added | XREF | Reactome:R-HSA-442368 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-06-09 | Updated | TERM | ferrous iron transmembrane transporter activity |
2010-06-08 | Updated | TERM | ferrous iron transmembrane transporter activity |
2007-07-14 | Updated | TERM | ferrous iron transmembrane transporter activity |
2003-03-19 | Updated | TERM | ferrous iron transporter activity |
2002-02-06 | Updated | TERM | ferrous iron transporter |
2001-04-03 | Updated | TERM | ferrous iron transporter |
2001-03-30 | Added | TERM | ferrous iron transporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-01 | Added | SYNONYM | ferrous iron uptake transmembrane transporter activity |
2015-05-11 | Deleted | DEFINITION | Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
2015-05-11 | Added | DEFINITION | Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
2007-07-27 | Updated | DEFINITION | Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
2003-03-26 | Added | DEFINITION | Enables the directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of, within or between cells. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-12-17 | Deleted | RELATION | is a GO:0072509 (divalent inorganic cation transmembrane transporter activity) |
2018-10-18 | Deleted | RELATION | part of GO:1903874 (ferrous iron transmembrane transport) |
2017-11-01 | Deleted | RELATION | part of GO:0015684 (ferrous iron transport) |
2017-05-22 | Added | RELATION | part of GO:0015684 (ferrous iron transport) |
2017-04-06 | Deleted | RELATION | part of GO:0015684 (ferrous iron transport) |
2015-03-06 | Added | RELATION | part of GO:1903874 (ferrous iron transmembrane transport) |
2010-12-19 | Added | RELATION | is a GO:0072509 (divalent inorganic cation transmembrane transporter activity) |
2010-06-15 | Added | RELATION | part of GO:0015684 (ferrous iron transport) |
2010-06-14 | Deleted | RELATION | part of GO:0015684 (ferrous iron transport) |
2010-06-08 | Added | RELATION | part of GO:0015684 (ferrous iron transport) |
2008-04-01 | Updated | RELATION | is a GO:0005381 (iron ion transmembrane transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-14 | Deleted | XREF | RHEA:28486 |
2024-02-24 | Added | XREF | MetaCyc:TRANS-RXN-8 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5655760 |
2019-04-01 | Added | XREF | Reactome:R-HSA-442368 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1362417 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-442368 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5655760 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1362417 |
2018-12-11 | Added | XREF | reactome:R-HSA-1362417 |
2018-12-11 | Added | XREF | reactome:R-HSA-442368 |
2018-07-13 | Added | XREF | RHEA:28486 |
2018-07-13 | Deleted | XREF | RHEA:28489 |
2012-09-14 | Added | XREF | RHEA:28489 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-01 | Added | SECONDARY | GO:0015639 (ferrous iron uptake transmembrane transporter activity) |
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