This term is obsolete.

GO:0015093 JSON

ferrous iron transmembrane transporter activity

Molecular Function

Definition (GO:0015093 GONUTS page)

Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.

Secondary IDs

GO:0015639

83,815 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ferrous iron uptake transmembrane transporter activity related

Ancestor Chart

Ancestor chart for GO:0015093
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015093

Child Term Relationship to
GO:0015093
high-affinity ferrous iron transmembrane transporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A2WLC1 39946 CDT3_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7MB71 9913 AT1B4_BOVIN GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein B4YDY0 10090 B4YDY0_MOUSE GO:0006811 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921
NOT-qualified manual protein B8B2D0 39946 CDT1_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D4ABB2 10116 D4ABB2_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q5VRD7 39947 CDT3_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q5VSB5 39947 CDT1_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q6R3K9 3702 YSL2_ARATH GO:0006826 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15753101
NOT-qualified manual protein Q6ZG85 39947 NRAT1_ORYSJ GO:0005381 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20937890

Cross-references

Database ID Description
InterPro IPR003373 Ferrous iron transport protein B
InterPro IPR011640 Ferrous iron transport protein B, C-terminal
MetaCyc TRANS-RXN-8
Reactome R-HSA-1362417
Reactome R-HSA-442368
Reactome R-HSA-5655760

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:29033 iron(2+)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0015093 based on ALL annotations
The top 100 of 349 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferrous iron transmembrane transporter activity
2,369.31 100.00 83,634 83,634
iron ion transmembrane transport
1,134.27 46.14 77,542 161,973
iron ion transmembrane transporter activity
1,591.12 26.50 25,462 37,915
zinc efflux antiporter activity
2,369.31 25.66 21,463 21,463
high-affinity iron permease complex
1,991.24 20.68 18,002 21,420
intracellular zinc ion homeostasis
851.82 17.66 21,547 59,932
cadmium ion transmembrane transporter activity
552.49 14.26 22,456 96,300
cadmium ion transmembrane transport
549.87 14.22 22,456 96,760
zinc ion transmembrane transport
372.58 10.82 21,550 137,040
iron ion transport
277.81 10.51 42,109 359,124
Totals 737427 131593639
No co-occurrence statistics for GO:0015093 based on MANUAL annotations
The top 100 of 162 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferrous iron transmembrane transporter activity
4,303.45 100.00 328 328
iron import into the mitochondrion
4,163.88 53.59 179 185
mitochondrial membrane
663.79 13.65 178 1,154
high-affinity iron permease complex
2,800.66 11.71 41 63
iron ion transmembrane transport
607.79 10.15 87 616
lead ion transmembrane transporter activity
4,098.53 6.08 20 21
zinc efflux antiporter activity
4,303.45 5.79 19 19
cobalt ion transmembrane transporter activity
1,031.04 5.74 23 96
cadmium ion binding
1,390.35 5.65 21 65
nickel cation transmembrane transporter activity
1,655.17 5.56 20 52
Totals 1389 36071

Change Log

Timestamp Action Category Detail
2024-09-14 Deleted XREF RHEA:28486
2024-02-24 Added XREF MetaCyc:TRANS-RXN-8
2020-12-17 Deleted RELATION is a GO:0072509 (divalent inorganic cation transmembrane transporter activity)
2019-05-04 Added XREF Reactome:R-HSA-5655760
2019-04-30 Deleted XREF Reactome:R-HSA-5655760
2019-04-29 Added XREF Reactome:R-HSA-5655760
2019-04-28 Deleted XREF Reactome:R-HSA-5655760
2019-04-27 Added XREF Reactome:R-HSA-5655760
2019-04-23 Deleted XREF Reactome:R-HSA-5655760
2019-04-01 Added XREF Reactome:R-HSA-442368
Timestamp Action Category Detail
2010-06-09 Updated TERM ferrous iron transmembrane transporter activity
2010-06-08 Updated TERM ferrous iron transmembrane transporter activity
2007-07-14 Updated TERM ferrous iron transmembrane transporter activity
2003-03-19 Updated TERM ferrous iron transporter activity
2002-02-06 Updated TERM ferrous iron transporter
2001-04-03 Updated TERM ferrous iron transporter
2001-03-30 Added TERM ferrous iron transporter
Timestamp Action Category Detail
2017-11-01 Added SYNONYM ferrous iron uptake transmembrane transporter activity
2015-05-11 Deleted DEFINITION Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
2015-05-11 Added DEFINITION Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
2008-05-13 Added DEFINITION Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
2007-07-27 Updated DEFINITION Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
2003-03-26 Added DEFINITION Enables the directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of, within or between cells.
Timestamp Action Category Detail
2020-12-17 Deleted RELATION is a GO:0072509 (divalent inorganic cation transmembrane transporter activity)
2018-10-18 Deleted RELATION part of GO:1903874 (ferrous iron transmembrane transport)
2017-11-01 Deleted RELATION part of GO:0015684 (ferrous iron transport)
2017-05-22 Added RELATION part of GO:0015684 (ferrous iron transport)
2017-04-06 Deleted RELATION part of GO:0015684 (ferrous iron transport)
2015-03-06 Added RELATION part of GO:1903874 (ferrous iron transmembrane transport)
2010-12-19 Added RELATION is a GO:0072509 (divalent inorganic cation transmembrane transporter activity)
2010-06-15 Added RELATION part of GO:0015684 (ferrous iron transport)
2010-06-14 Deleted RELATION part of GO:0015684 (ferrous iron transport)
2010-06-08 Added RELATION part of GO:0015684 (ferrous iron transport)
2008-04-01 Updated RELATION is a GO:0005381 (iron ion transmembrane transporter activity)
Timestamp Action Category Detail
2024-09-14 Deleted XREF RHEA:28486
2024-02-24 Added XREF MetaCyc:TRANS-RXN-8
2019-05-04 Added XREF Reactome:R-HSA-5655760
2019-04-30 Deleted XREF Reactome:R-HSA-5655760
2019-04-29 Added XREF Reactome:R-HSA-5655760
2019-04-28 Deleted XREF Reactome:R-HSA-5655760
2019-04-27 Added XREF Reactome:R-HSA-5655760
2019-04-23 Deleted XREF Reactome:R-HSA-5655760
2019-04-01 Added XREF Reactome:R-HSA-442368
2019-04-01 Deleted XREF reactome:R-HSA-1362417
2019-04-01 Deleted XREF reactome:R-HSA-442368
2019-04-01 Added XREF Reactome:R-HSA-5655760
2019-04-01 Added XREF Reactome:R-HSA-1362417
2018-12-11 Added XREF reactome:R-HSA-1362417
2018-12-11 Added XREF reactome:R-HSA-442368
2018-07-13 Added XREF RHEA:28486
2018-07-13 Deleted XREF RHEA:28489
2012-09-14 Added XREF RHEA:28489
Timestamp Action Category Detail
2017-11-01 Added SECONDARY GO:0015639 (ferrous iron uptake transmembrane transporter activity)
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