This term is obsolete.

GO:0015936 JSON

coenzyme A metabolic process

Biological Process

Definition (GO:0015936 GONUTS page)

The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.

Secondary IDs

GO:0006763

242,840 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
CoA metabolism exact
coenzyme A metabolism exact

Ancestor Chart

Ancestor chart for GO:0015936
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015936

Child Term Relationship to
GO:0015936
GO:0015938
coenzyme A catabolic process
is_a
GO:0015937
coenzyme A biosynthetic process
is_a

Cross-references

Database ID Description
InterPro IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II
InterPro IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type
InterPro IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:57287 coenzyme A(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0015936 based on ALL annotations
The top 100 of 557 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0015936
coenzyme A metabolic process
9,599.60 100.00 20,642 20,642
GO:0004420
hydroxymethylglutaryl-CoA reductase (NADPH) activity
9,283.87 95.65 20,407 21,101
GO:0140643
hydroxymethylglutaryl-CoA reductase (NADH) activity
9,592.78 20.45 4,222 4,225
GO:0016126
sterol biosynthetic process
1,077.20 9.05 6,585 58,683
GO:0005778
peroxisomal membrane
578.25 5.38 6,942 115,244
GO:0006696
ergosterol biosynthetic process
648.92 4.22 2,090 30,918
GO:0008299
isoprenoid biosynthetic process
210.94 2.15 10,478 476,837
GO:0042170
plastid membrane
891.04 1.83 459 4,945
GO:0004496
mevalonate kinase activity
171.80 0.73 250 13,969
GO:0005789
endoplasmic reticulum membrane
53.90 0.56 7,105 1,265,429
Totals 116225 79630270
No co-occurrence statistics for GO:0015936 based on MANUAL annotations
The top 78 of 78 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0015936
coenzyme A metabolic process
100,823.79 100.00 14 14
GO:0018787
4-chlorobenzoyl-CoA dehalogenase activity
100,823.79 14.29 2 2
GO:1902860
propionyl-CoA biosynthetic process
100,823.79 14.29 2 2
GO:0016453
C-acetyltransferase activity
67,215.86 13.33 2 3
GO:0046952
ketone body catabolic process
40,329.52 11.76 2 5
GO:0051791
medium-chain fatty acid metabolic process
18,904.46 11.11 3 16
GO:0034736
cholesterol O-acyltransferase activity
16,803.97 8.33 2 12
GO:0120225
coenzyme A binding
15,511.35 8.00 2 13
GO:0008458
carnitine O-octanoyltransferase activity
9,378.96 7.55 4 43
GO:0072229
metanephric proximal convoluted tubule development
100,823.79 7.14 1 1
Totals 142 727205

Change Log

Timestamp Action Category Detail
2024-08-20 Added RELATION is a GO:0006790 (sulfur compound metabolic process)
2024-08-20 Deleted RELATION is a GO:0009150 (purine ribonucleotide metabolic process)
2024-08-20 Deleted RELATION is a GO:0033875 (ribonucleoside bisphosphate metabolic process)
2024-08-20 Deleted RELATION is a GO:0034032 (purine nucleoside bisphosphate metabolic process)
2024-08-20 Added RELATION is a GO:0006753 (nucleoside phosphate metabolic process)
2024-08-20 Added RELATION is a GO:0043603 (amide metabolic process)
2024-08-20 Added RELATION is a GO:0072521 (purine-containing compound metabolic process)
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-02-23 Deleted RELATION is a GO:0046128 (purine ribonucleoside metabolic process)
2012-11-02 Added RELATION is a GO:0034032 (purine nucleoside bisphosphate metabolic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM coenzyme A metabolic process
2002-02-06 Updated TERM coenzyme A metabolism
2001-04-03 Updated TERM coenzyme A metabolism
2001-03-30 Added TERM coenzyme A metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2007-08-09 Added SYNONYM CoA metabolism
2007-08-09 Deleted SYNONYM CoA metabolism
2007-08-09 Deleted SYNONYM coenzyme A metabolism
2007-08-09 Added SYNONYM coenzyme A metabolism
2007-02-23 Added SYNONYM CoA metabolism
2007-01-29 Added SYNONYM coenzyme A metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2005-01-21 Updated DEFINITION The chemical reactions involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2002-11-27 Updated DEFINITION The chemical reactions and physical changes involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2001-08-06 Added DEFINITION Metabolism of coenzyme A: 3'-phosphoadenosine-(5')diphospho(4')pantatheine; an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Timestamp Action Category Detail
2024-08-20 Added RELATION is a GO:0006790 (sulfur compound metabolic process)
2024-08-20 Deleted RELATION is a GO:0009150 (purine ribonucleotide metabolic process)
2024-08-20 Deleted RELATION is a GO:0033875 (ribonucleoside bisphosphate metabolic process)
2024-08-20 Deleted RELATION is a GO:0034032 (purine nucleoside bisphosphate metabolic process)
2024-08-20 Added RELATION is a GO:0006753 (nucleoside phosphate metabolic process)
2024-08-20 Added RELATION is a GO:0043603 (amide metabolic process)
2024-08-20 Added RELATION is a GO:0072521 (purine-containing compound metabolic process)
2020-05-09 Deleted RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2017-02-23 Deleted RELATION is a GO:0046128 (purine ribonucleoside metabolic process)
2012-11-02 Added RELATION is a GO:0034032 (purine nucleoside bisphosphate metabolic process)
2012-11-02 Deleted RELATION is a GO:0033865 (nucleoside bisphosphate metabolic process)
2012-11-02 Added RELATION is a GO:0009150 (purine ribonucleotide metabolic process)
2012-11-02 Added RELATION is a GO:0033875 (ribonucleoside bisphosphate metabolic process)
2010-10-11 Deleted RELATION is a GO:0006752 (group transfer coenzyme metabolic process)
2010-10-11 Added RELATION is a GO:0006732 (obsolete coenzyme metabolic process)
2009-07-06 Added RELATION is a GO:0046128 (purine ribonucleoside metabolic process)
2009-07-03 Added RELATION is a GO:0033865 (nucleoside bisphosphate metabolic process)
2008-04-01 Updated RELATION is a GO:0006752 (group transfer coenzyme metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
2005-09-02 Added SECONDARY GO:0006763 (coenzyme A metabolism)
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