GO:0016154
JSON
pyrimidine-nucleoside phosphorylase activity
Molecular Function
Definition (GO:0016154 GONUTS page)
Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Py-NPase activity | related |
pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016154
Child Term | Relationship to GO:0016154 |
---|---|
uridine phosphorylase activity
|
is_a |
deoxyuridine phosphorylase activity
|
is_a |
thymidine phosphorylase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016757 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A6KJI3 | 10116 | A6KJI3_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D6WQD5 | 7070 | D6WQD5_TRICA | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q6AYL7 | 10116 | Q6AYL7_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7JRM5 | 7227 | Q7JRM5_DROME | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.4.2.2 | |
InterPro | IPR018090 | Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016154 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyrimidine-nucleoside phosphorylase activity
|
8,968.06 | 100.00 | 21,737 | 21,737 |
thymidine phosphorylase activity
|
5,961.31 | 60.07 | 18,732 | 28,180 |
pyrimidine nucleoside metabolic process
|
5,473.54 | 46.36 | 14,313 | 23,451 |
pyrimidine nucleobase metabolic process
|
4,089.14 | 36.89 | 14,321 | 31,408 |
deoxyuridine phosphorylase activity
|
6,028.47 | 35.74 | 9,409 | 13,997 |
1,4-alpha-oligoglucan phosphorylase activity
|
2,702.61 | 26.07 | 14,317 | 47,508 |
guanosine phosphorylase activity
|
7,746.57 | 22.95 | 5,175 | 5,991 |
uridine phosphorylase activity
|
2,776.89 | 18.18 | 6,644 | 21,457 |
purine-nucleoside phosphorylase activity
|
1,185.35 | 10.53 | 7,417 | 56,115 |
pentosyltransferase activity
|
439.30 | 4.77 | 13,997 | 285,741 |
Totals | 171204 | 243962878 |
No co-occurrence statistics for GO:0016154 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyrimidine-nucleoside phosphorylase activity
|
117,436.27 | 100.00 | 11 | 11 |
purine-nucleoside phosphorylase activity
|
8,728.37 | 7.43 | 11 | 148 |
protein homodimerization activity
|
22.08 | 0.02 | 1 | 5,319 |
cytosol
|
15.34 | 0.01 | 11 | 84,217 |
cellular_component
|
5.62 | 0.00 | 3 | 62,739 |
biological_process
|
5.30 | 0.00 | 3 | 66,439 |
molecular_function
|
5.06 | 0.00 | 3 | 69,561 |
Totals | 43 | 288434 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-08-11 | Deleted | XREF | MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN |
2020-10-08 | Deleted | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | Py-NPase activity |
2020-10-08 | Added | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2020-10-08 | Added | SYNONYM | Py-NPase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
2008-04-01 | Updated | RELATION | is a GO:0016763 (pentosyltransferase activity) |
2007-11-08 | Added | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2007-09-06 | Added | SYNONYM | Py-NPase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | pyrimidine-nucleoside phosphorylase activity |
2002-02-06 | Updated | TERM | pyrimidine-nucleoside phosphorylase |
2001-04-03 | Updated | TERM | pyrimidine-nucleoside phosphorylase |
2001-03-30 | Added | TERM | pyrimidine-nucleoside phosphorylase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | Py-NPase activity |
2020-10-08 | Added | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2020-10-08 | Added | SYNONYM | Py-NPase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
2007-11-08 | Added | SYNONYM | pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity |
2007-09-06 | Added | SYNONYM | Py-NPase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016763 (pentosyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-08-11 | Deleted | XREF | MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN |
2003-10-27 | Added | XREF | MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN |
2001-03-30 | Added | XREF | EC:2.4.2.2 |
Timestamp | Action | Category | Detail |
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