GO:0016435
JSON
rRNA (guanine) methyltransferase activity
Molecular Function
Definition (GO:0016435 GONUTS page)
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
Ancestor Chart
Ancestor chart for GO:0016435
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016435
Child Term | Relationship to GO:0016435 |
---|---|
rRNA (guanine-N1-)-methyltransferase activity
|
is_a |
rRNA (guanine-N7-)-methyltransferase activity
|
is_a |
rRNA (guanine-N2-)-methyltransferase activity
|
is_a |
rRNA (guanosine-2'-O-)-methyltransferase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I5YBY9 | 10116 | A0A8I5YBY9_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AGH5 | 10116 | A0A8I6AGH5_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A2VDP2 | 9913 | PCMD1_BOVIN | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6JFH4 | 10116 | A6JFH4_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JFH5 | 10116 | A6JFH5_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7XRZ1 | 227321 | TDIE_EMENI | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773 | |
NOT-qualified manual | protein | D3Z930 | 10116 | D3Z930_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A629 | 10116 | D4A629_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR022238 | 18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal |
InterPro | IPR039769 | 18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016435 based on ALL annotations
The top 100 of 297 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
rRNA (guanine) methyltransferase activity
|
15,820.75 | 100.00 | 12,525 | 12,525 |
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
|
3,124.57 | 14.35 | 4,310 | 21,823 |
rRNA (uridine-2'-O-)-methyltransferase activity
|
2,674.86 | 12.79 | 4,310 | 25,492 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
|
1,227.25 | 6.76 | 4,310 | 55,561 |
rRNA (guanine-N7)-methylation
|
1,115.12 | 6.38 | 5,042 | 71,533 |
preribosome, large subunit precursor
|
916.76 | 5.22 | 4,310 | 74,379 |
rRNA modification
|
698.31 | 3.91 | 3,173 | 71,887 |
rRNA methyltransferase activity
|
628.96 | 3.60 | 3,466 | 87,183 |
rRNA methylation
|
354.07 | 2.20 | 7,483 | 334,361 |
tRNA (m2G10) methyltransferase complex
|
6,058.34 | 1.50 | 193 | 504 |
Totals | 121513 | 67080443 |
No co-occurrence statistics for GO:0016435 based on MANUAL annotations
The top 53 of 53 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
rRNA (guanine) methyltransferase activity
|
3,953.87 | 100.00 | 357 | 357 |
rRNA (guanine-N7)-methylation
|
3,740.97 | 33.79 | 123 | 130 |
rRNA (uridine-2'-O-)-methyltransferase activity
|
2,214.17 | 29.98 | 140 | 250 |
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
|
1,882.80 | 27.40 | 140 | 294 |
rRNA modification
|
3,409.76 | 25.27 | 94 | 109 |
rRNA methylation
|
634.96 | 12.89 | 141 | 878 |
preribosome, large subunit precursor
|
297.44 | 6.74 | 140 | 1,861 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
|
288.00 | 6.55 | 140 | 1,922 |
nucleolus
|
57.80 | 1.45 | 262 | 17,922 |
rRNA (guanosine-2'-O-)-methyltransferase activity
|
930.32 | 1.08 | 4 | 17 |
Totals | 1676 | 702133 |
Change Log
- All changes
- All changes
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-16 | Deleted | XREF | EC:2.1.1 |
2016-10-03 | Added | XREF | EC:2.1.1 |
2016-10-03 | Deleted | XREF | EC:2.1.1.- |
2012-03-01 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine. |
2012-03-01 | Deleted | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2008-04-01 | Updated | RELATION | is a GO:0008649 (rRNA methyltransferase activity) |
2003-06-18 | Added | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2003-03-19 | Updated | TERM | rRNA (guanine) methyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | rRNA (guanine) methyltransferase activity |
2002-02-06 | Updated | TERM | rRNA (guanine) methyltransferase |
2001-04-03 | Updated | TERM | rRNA (guanine) methyltransferase |
2001-03-30 | Added | TERM | rRNA (guanine) methyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-03-01 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine. |
2012-03-01 | Deleted | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
2003-06-18 | Added | DEFINITION | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008649 (rRNA methyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-16 | Deleted | XREF | EC:2.1.1 |
2016-10-03 | Added | XREF | EC:2.1.1 |
2016-10-03 | Deleted | XREF | EC:2.1.1.- |
2001-03-30 | Added | XREF | EC:2.1.1.- |
Timestamp | Action | Category | Detail |
---|
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