This term is obsolete.

GO:0016435 JSON

rRNA (guanine) methyltransferase activity

Molecular Function

Definition (GO:0016435 GONUTS page)

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.

155,750 annotations

Ancestor Chart

Ancestor chart for GO:0016435
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016435

Child Term Relationship to
GO:0016435
rRNA (guanine-N1-)-methyltransferase activity
is_a
rRNA (guanine-N7-)-methyltransferase activity
is_a
rRNA (guanine-N2-)-methyltransferase activity
is_a
rRNA (guanosine-2'-O-)-methyltransferase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I5YBY9 10116 A0A8I5YBY9_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AGH5 10116 A0A8I6AGH5_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A2VDP2 9913 PCMD1_BOVIN GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6JFH4 10116 A6JFH4_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JFH5 10116 A6JFH5_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7XRZ1 227321 TDIE_EMENI GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773
NOT-qualified manual protein D3Z930 10116 D3Z930_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A629 10116 D4A629_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
InterPro IPR022238 18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal
InterPro IPR039769 18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016435 based on ALL annotations
The top 100 of 297 co-occurring terms
Co-occurring Term PR S% #Together #Compared
rRNA (guanine) methyltransferase activity
15,820.75 100.00 12,525 12,525
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
3,124.57 14.35 4,310 21,823
rRNA (uridine-2'-O-)-methyltransferase activity
2,674.86 12.79 4,310 25,492
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
1,227.25 6.76 4,310 55,561
rRNA (guanine-N7)-methylation
1,115.12 6.38 5,042 71,533
preribosome, large subunit precursor
916.76 5.22 4,310 74,379
rRNA modification
698.31 3.91 3,173 71,887
rRNA methyltransferase activity
628.96 3.60 3,466 87,183
rRNA methylation
354.07 2.20 7,483 334,361
tRNA (m2G10) methyltransferase complex
6,058.34 1.50 193 504
Totals 121513 67080443
No co-occurrence statistics for GO:0016435 based on MANUAL annotations
The top 53 of 53 co-occurring terms
Co-occurring Term PR S% #Together #Compared
rRNA (guanine) methyltransferase activity
3,953.87 100.00 357 357
rRNA (guanine-N7)-methylation
3,740.97 33.79 123 130
rRNA (uridine-2'-O-)-methyltransferase activity
2,214.17 29.98 140 250
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
1,882.80 27.40 140 294
rRNA modification
3,409.76 25.27 94 109
rRNA methylation
634.96 12.89 141 878
preribosome, large subunit precursor
297.44 6.74 140 1,861
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
288.00 6.55 140 1,922
nucleolus
57.80 1.45 262 17,922
rRNA (guanosine-2'-O-)-methyltransferase activity
930.32 1.08 4 17
Totals 1676 702133

Change Log

Timestamp Action Category Detail
2019-05-16 Deleted XREF EC:2.1.1
2016-10-03 Added XREF EC:2.1.1
2016-10-03 Deleted XREF EC:2.1.1.-
2012-03-01 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
2012-03-01 Deleted DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2008-05-13 Added DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2008-04-01 Updated RELATION is a GO:0008649 (rRNA methyltransferase activity)
2003-06-18 Added DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2003-03-19 Updated TERM rRNA (guanine) methyltransferase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM rRNA (guanine) methyltransferase activity
2002-02-06 Updated TERM rRNA (guanine) methyltransferase
2001-04-03 Updated TERM rRNA (guanine) methyltransferase
2001-03-30 Added TERM rRNA (guanine) methyltransferase
Timestamp Action Category Detail
2012-03-01 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
2012-03-01 Deleted DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2008-05-13 Added DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
2003-06-18 Added DEFINITION Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008649 (rRNA methyltransferase activity)
Timestamp Action Category Detail
2019-05-16 Deleted XREF EC:2.1.1
2016-10-03 Added XREF EC:2.1.1
2016-10-03 Deleted XREF EC:2.1.1.-
2001-03-30 Added XREF EC:2.1.1.-
Timestamp Action Category Detail
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