GO:0016799
JSON
hydrolase activity, hydrolyzing N-glycosyl compounds
Molecular Function
Definition (GO:0016799 GONUTS page)
Catalysis of the hydrolysis of any N-glycosyl bond.
Ancestor Chart
Ancestor chart for GO:0016799
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016799
Child Term | Relationship to GO:0016799 |
---|---|
purine nucleosidase activity
|
is_a |
DNA-deoxyinosine glycosylase activity
|
is_a |
cytokinin riboside 5'-monophosphate phosphoribohydrolase activity
|
is_a |
deoxyribodipyrimidine endonucleosidase activity
|
is_a |
6-amino-6-deoxyfutalosine hydrolase activity
|
is_a |
1-methyladenosine nucleosidase activity
|
is_a |
NMN nucleosidase activity
|
is_a |
adenosylhomocysteine nucleosidase activity
|
is_a |
RNA glycosylase activity
|
is_a |
nicotinamide riboside hydrolase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q91YD4 | 10090 | TRPM2_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q93Y07 | 3702 | SFR2_ARATH | GO:0016798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.2.2.- | |
InterPro | IPR000214 | Zinc finger, DNA glycosylase/AP lyase-type |
InterPro | IPR001910 | Inosine/uridine-preferring nucleoside hydrolase domain |
InterPro | IPR012092 | 8-oxoguanine DNA glycosylase/AP lyase Ogg |
InterPro | IPR015254 | N-glycosylase/DNA lyase-like |
InterPro | IPR015886 | DNA glycosylase/AP lyase, H2TH DNA-binding |
InterPro | IPR015887 | DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site |
InterPro | IPR015910 | Inosine/uridine-preferring nucleoside hydrolase, conserved site |
InterPro | IPR018085 | Uracil-DNA glycosylase, active site |
InterPro | IPR019963 | Futalosine hydrolase |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016799 based on ALL annotations
The top 100 of 747 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hydrolase activity, hydrolyzing N-glycosyl compounds
|
2,207.71 | 100.00 | 89,756 | 89,756 |
purine nucleosidase activity
|
2,131.61 | 38.93 | 35,434 | 36,699 |
purine nucleoside catabolic process
|
1,239.11 | 30.10 | 35,329 | 62,945 |
cytokinin biosynthetic process
|
1,196.81 | 25.79 | 29,600 | 54,602 |
nucleobase-containing compound metabolic process
|
273.11 | 10.93 | 43,454 | 351,264 |
uridine nucleosidase activity
|
1,908.84 | 8.42 | 7,658 | 8,857 |
AMP nucleosidase activity
|
567.03 | 6.34 | 6,973 | 27,149 |
cytokinin riboside 5'-monophosphate phosphoribohydrolase activity
|
1,230.89 | 3.90 | 3,614 | 6,482 |
adenosylhomocysteine nucleosidase activity
|
274.54 | 3.14 | 3,616 | 29,078 |
methylthioadenosine nucleosidase activity
|
270.11 | 3.13 | 3,616 | 29,555 |
Totals | 459012 | 62351778 |
No co-occurrence statistics for GO:0016799 based on MANUAL annotations
The top 38 of 38 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hydrolase activity, hydrolyzing N-glycosyl compounds
|
100,823.79 | 100.00 | 14 | 14 |
mannosidase activity
|
67,215.86 | 35.29 | 6 | 9 |
carbohydrate derivative metabolic process
|
84,019.82 | 33.33 | 5 | 6 |
FAD metabolic process
|
50,411.90 | 6.67 | 1 | 2 |
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
|
25,205.95 | 5.88 | 1 | 4 |
5-amino-6-(5-phosphoribosylamino)uracil reductase activity
|
20,164.76 | 5.56 | 1 | 5 |
nucleobase-containing small molecule catabolic process
|
7,755.68 | 3.85 | 1 | 13 |
respiratory gaseous exchange by respiratory system
|
3,009.67 | 2.53 | 2 | 67 |
GTP cyclohydrolase II activity
|
2,016.48 | 1.59 | 1 | 50 |
retina morphogenesis in camera-type eye
|
1,563.16 | 1.42 | 2 | 129 |
Totals | 88 | 206329 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:3.2.2 |
2021-01-04 | Added | XREF | EC:3.2.2.- |
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
2008-04-01 | Updated | RELATION | is a GO:0016798 (hydrolase activity, acting on glycosyl bonds) |
2007-10-25 | Added | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
2006-02-09 | Added | XREF | EC:3.2.2 |
2006-02-09 | Deleted | XREF | EC:3.2.2.- |
2003-03-25 | Updated | TERM | hydrolase activity, hydrolyzing N-glycosyl compounds |
2003-03-19 | Updated | TERM | hydrolase, hydrolyzing N-glycosyl compounds activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-25 | Updated | TERM | hydrolase activity, hydrolyzing N-glycosyl compounds |
2003-03-19 | Updated | TERM | hydrolase, hydrolyzing N-glycosyl compounds activity |
2002-02-06 | Updated | TERM | hydrolase, hydrolyzing N-glycosyl compounds |
2001-04-03 | Updated | TERM | hydrolase, hydrolyzing N-glycosyl compounds |
2001-03-30 | Added | TERM | hydrolase, hydrolyzing N-glycosyl compounds |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
2007-10-25 | Added | DEFINITION | Catalysis of the hydrolysis of any N-glycosyl bond. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016798 (hydrolase activity, acting on glycosyl bonds) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:3.2.2 |
2021-01-04 | Added | XREF | EC:3.2.2.- |
2006-02-09 | Added | XREF | EC:3.2.2 |
2006-02-09 | Deleted | XREF | EC:3.2.2.- |
2001-03-30 | Added | XREF | EC:3.2.2.- |
Timestamp | Action | Category | Detail |
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