This term is obsolete.

GO:0016799 JSON

hydrolase activity, hydrolyzing N-glycosyl compounds

Molecular Function

Definition (GO:0016799 GONUTS page)

Catalysis of the hydrolysis of any N-glycosyl bond.

880,109 annotations

Ancestor Chart

Ancestor chart for GO:0016799
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016799

Child Term Relationship to
GO:0016799
purine nucleosidase activity
is_a
DNA-deoxyinosine glycosylase activity
is_a
cytokinin riboside 5'-monophosphate phosphoribohydrolase activity
is_a
deoxyribodipyrimidine endonucleosidase activity
is_a
6-amino-6-deoxyfutalosine hydrolase activity
is_a
1-methyladenosine nucleosidase activity
is_a
NMN nucleosidase activity
is_a
adenosylhomocysteine nucleosidase activity
is_a
RNA glycosylase activity
is_a
nicotinamide riboside hydrolase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q93Y07 3702 SFR2_ARATH GO:0016798 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25100720

Cross-references

Database ID Description
EC 3.2.2.-
InterPro IPR000214 Zinc finger, DNA glycosylase/AP lyase-type
InterPro IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain
InterPro IPR012092 8-oxoguanine DNA glycosylase/AP lyase Ogg
InterPro IPR015254 N-glycosylase/DNA lyase-like
InterPro IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding
InterPro IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site
InterPro IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site
InterPro IPR018085 Uracil-DNA glycosylase, active site
InterPro IPR019963 Futalosine hydrolase

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016799 based on ALL annotations
The top 100 of 747 co-occurring terms
Co-occurring Term PR S% #Together #Compared
hydrolase activity, hydrolyzing N-glycosyl compounds
2,207.71 100.00 89,756 89,756
purine nucleosidase activity
2,131.61 38.93 35,434 36,699
purine nucleoside catabolic process
1,239.11 30.10 35,329 62,945
cytokinin biosynthetic process
1,196.81 25.79 29,600 54,602
nucleobase-containing compound metabolic process
273.11 10.93 43,454 351,264
uridine nucleosidase activity
1,908.84 8.42 7,658 8,857
AMP nucleosidase activity
567.03 6.34 6,973 27,149
cytokinin riboside 5'-monophosphate phosphoribohydrolase activity
1,230.89 3.90 3,614 6,482
adenosylhomocysteine nucleosidase activity
274.54 3.14 3,616 29,078
methylthioadenosine nucleosidase activity
270.11 3.13 3,616 29,555
Totals 459012 62351778
No co-occurrence statistics for GO:0016799 based on MANUAL annotations
The top 38 of 38 co-occurring terms
Co-occurring Term PR S% #Together #Compared
hydrolase activity, hydrolyzing N-glycosyl compounds
100,823.79 100.00 14 14
mannosidase activity
67,215.86 35.29 6 9
carbohydrate derivative metabolic process
84,019.82 33.33 5 6
FAD metabolic process
50,411.90 6.67 1 2
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
25,205.95 5.88 1 4
5-amino-6-(5-phosphoribosylamino)uracil reductase activity
20,164.76 5.56 1 5
nucleobase-containing small molecule catabolic process
7,755.68 3.85 1 13
respiratory gaseous exchange by respiratory system
3,009.67 2.53 2 67
GTP cyclohydrolase II activity
2,016.48 1.59 1 50
retina morphogenesis in camera-type eye
1,563.16 1.42 2 129
Totals 88 206329

Change Log

Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:3.2.2
2021-01-04 Added XREF EC:3.2.2.-
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
2008-04-01 Updated RELATION is a GO:0016798 (hydrolase activity, acting on glycosyl bonds)
2007-10-25 Added DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
2006-02-09 Added XREF EC:3.2.2
2006-02-09 Deleted XREF EC:3.2.2.-
2003-03-25 Updated TERM hydrolase activity, hydrolyzing N-glycosyl compounds
2003-03-19 Updated TERM hydrolase, hydrolyzing N-glycosyl compounds activity
Timestamp Action Category Detail
2003-03-25 Updated TERM hydrolase activity, hydrolyzing N-glycosyl compounds
2003-03-19 Updated TERM hydrolase, hydrolyzing N-glycosyl compounds activity
2002-02-06 Updated TERM hydrolase, hydrolyzing N-glycosyl compounds
2001-04-03 Updated TERM hydrolase, hydrolyzing N-glycosyl compounds
2001-03-30 Added TERM hydrolase, hydrolyzing N-glycosyl compounds
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
2007-10-25 Added DEFINITION Catalysis of the hydrolysis of any N-glycosyl bond.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016798 (hydrolase activity, acting on glycosyl bonds)
Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:3.2.2
2021-01-04 Added XREF EC:3.2.2.-
2006-02-09 Added XREF EC:3.2.2
2006-02-09 Deleted XREF EC:3.2.2.-
2001-03-30 Added XREF EC:3.2.2.-
Timestamp Action Category Detail
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