This term is obsolete.

GO:0016813 JSON

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

Molecular Function

Definition (GO:0016813 GONUTS page)

Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.

263,208 annotations

Ancestor Chart

Ancestor chart for GO:0016813
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016813

Child Term Relationship to
GO:0016813
amidinoaspartase activity
is_a
guanidinopropionase activity
is_a
guanidinobutyrase activity
is_a
guanidinoacetase activity
is_a
arginine deiminase activity
is_a
aminopropylagmatine ureohydrolase activity
is_a
diguanidinobutanase activity
is_a
formimidoylglutamate deiminase activity
is_a
formimidoylglutamase activity
is_a
formimidoylaspartate deiminase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9NHA8 7227 BGBP3_DROME GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089

Cross-references

Database ID Description
EC 3.5.3.-
InterPro IPR010158 Amidase, carbamoylase-type
InterPro IPR020855 Ureohydrolase, manganese-binding site

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016813 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term PR S% #Together #Compared
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2,644.00 100.00 74,945 74,945
putrescine biosynthetic process from arginine, via agmatine
2,236.71 51.76 42,829 50,628
agmatinase activity
2,233.42 51.72 42,832 50,706
N-carbamoyl-L-amino-acid hydrolase activity
2,611.86 2.60 1,950 1,974
purine nucleobase metabolic process
73.72 1.39 2,010 72,085
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
41.36 1.37 7,624 487,406
putrescine biosynthetic process
116.48 1.10 1,080 24,516
putrescine biosynthetic process from arginine
99.50 1.05 1,076 28,592
allantoin metabolic process
254.48 0.99 818 8,499
guanidinobutyrase activity
2,605.35 0.90 674 684
Totals 321142 96240998
No co-occurrence statistics for GO:0016813 based on MANUAL annotations
The top 4 of 4 co-occurring terms
Co-occurring Term PR S% #Together #Compared
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
470,511.00 100.00 3 3
putrescine biosynthetic process from arginine, via agmatine
3,075.24 0.65 1 153
agmatinase activity
3,075.24 0.65 1 153
spermidine biosynthetic process
1,656.73 0.35 2 568
Totals 7 877

Change Log

Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:3.5.3
2021-01-04 Added XREF EC:3.5.3.-
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
2008-04-01 Updated RELATION is a GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds)
2006-02-09 Added XREF EC:3.5.3
2006-02-09 Deleted XREF EC:3.5.3.-
2003-07-23 Added DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
2003-03-25 Updated TERM hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2003-03-19 Updated TERM hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines activity
Timestamp Action Category Detail
2003-03-25 Updated TERM hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2003-03-19 Updated TERM hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines activity
2002-02-06 Updated TERM hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2001-04-03 Updated TERM hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2001-03-30 Added TERM hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
2003-07-23 Added DEFINITION Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds)
Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:3.5.3
2021-01-04 Added XREF EC:3.5.3.-
2006-02-09 Added XREF EC:3.5.3
2006-02-09 Deleted XREF EC:3.5.3.-
2001-03-30 Added XREF EC:3.5.3.-
Timestamp Action Category Detail
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