GO:0016813
JSON
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Molecular Function
Definition (GO:0016813 GONUTS page)
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
Ancestor Chart
Ancestor chart for GO:0016813
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016813
Child Term | Relationship to GO:0016813 |
---|---|
amidinoaspartase activity
|
is_a |
guanidinopropionase activity
|
is_a |
guanidinobutyrase activity
|
is_a |
guanidinoacetase activity
|
is_a |
arginine deiminase activity
|
is_a |
aminopropylagmatine ureohydrolase activity
|
is_a |
diguanidinobutanase activity
|
is_a |
formimidoylglutamate deiminase activity
|
is_a |
formimidoylglutamase activity
|
is_a |
formimidoylaspartate deiminase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q91YD4 | 10090 | TRPM2_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q9NHA8 | 7227 | BGBP3_DROME | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.5.3.- | |
InterPro | IPR010158 | Amidase, carbamoylase-type |
InterPro | IPR020855 | Ureohydrolase, manganese-binding site |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016813 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
|
2,644.00 | 100.00 | 74,945 | 74,945 |
putrescine biosynthetic process from arginine, via agmatine
|
2,236.71 | 51.76 | 42,829 | 50,628 |
agmatinase activity
|
2,233.42 | 51.72 | 42,832 | 50,706 |
N-carbamoyl-L-amino-acid hydrolase activity
|
2,611.86 | 2.60 | 1,950 | 1,974 |
purine nucleobase metabolic process
|
73.72 | 1.39 | 2,010 | 72,085 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
|
41.36 | 1.37 | 7,624 | 487,406 |
putrescine biosynthetic process
|
116.48 | 1.10 | 1,080 | 24,516 |
putrescine biosynthetic process from arginine
|
99.50 | 1.05 | 1,076 | 28,592 |
allantoin metabolic process
|
254.48 | 0.99 | 818 | 8,499 |
guanidinobutyrase activity
|
2,605.35 | 0.90 | 674 | 684 |
Totals | 321142 | 96240998 |
No co-occurrence statistics for GO:0016813 based on MANUAL annotations
The top 4 of 4 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
|
470,511.00 | 100.00 | 3 | 3 |
putrescine biosynthetic process from arginine, via agmatine
|
3,075.24 | 0.65 | 1 | 153 |
agmatinase activity
|
3,075.24 | 0.65 | 1 | 153 |
spermidine biosynthetic process
|
1,656.73 | 0.35 | 2 | 568 |
Totals | 7 | 877 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:3.5.3 |
2021-01-04 | Added | XREF | EC:3.5.3.- |
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
2008-04-01 | Updated | RELATION | is a GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds) |
2006-02-09 | Added | XREF | EC:3.5.3 |
2006-02-09 | Deleted | XREF | EC:3.5.3.- |
2003-07-23 | Added | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
2003-03-25 | Updated | TERM | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
2003-03-19 | Updated | TERM | hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-25 | Updated | TERM | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
2003-03-19 | Updated | TERM | hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines activity |
2002-02-06 | Updated | TERM | hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
2001-04-03 | Updated | TERM | hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
2001-03-30 | Added | TERM | hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
2003-07-23 | Added | DEFINITION | Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:3.5.3 |
2021-01-04 | Added | XREF | EC:3.5.3.- |
2006-02-09 | Added | XREF | EC:3.5.3 |
2006-02-09 | Deleted | XREF | EC:3.5.3.- |
2001-03-30 | Added | XREF | EC:3.5.3.- |
Timestamp | Action | Category | Detail |
---|
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