GO:0016849
JSON
phosphorus-oxygen lyase activity
Molecular Function
Definition (GO:0016849 GONUTS page)
Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Ancestor Chart
Ancestor chart for GO:0016849
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016849
Child Term | Relationship to GO:0016849 |
---|---|
adenylate cyclase activity
|
is_a |
cyclic pyranopterin monophosphate synthase activity
|
is_a |
cytidylate cyclase activity
|
is_a |
guanylate cyclase activity
|
is_a |
FAD-AMP lyase (cyclizing) activity
|
is_a |
ribonuclease T2 activity
|
is_a |
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
|
is_a |
phosphatidylinositol diacylglycerol-lyase activity
|
is_a |
glycosylphosphatidylinositol diacylglycerol-lyase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.6.-.- | |
InterPro | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016849 based on ALL annotations
The top 100 of 594 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorus-oxygen lyase activity
|
6,711.84 | 100.00 | 29,044 | 29,044 |
receptor guanylyl cyclase signaling pathway
|
2,984.77 | 26.18 | 11,295 | 25,399 |
guanylate cyclase activity
|
2,609.70 | 26.07 | 12,833 | 33,005 |
peptide receptor activity
|
3,204.74 | 25.07 | 10,037 | 21,021 |
cyclase activity
|
3,931.32 | 25.01 | 8,824 | 15,065 |
cGMP biosynthetic process
|
2,402.06 | 24.76 | 12,940 | 36,157 |
cyclic nucleotide biosynthetic process
|
1,212.30 | 17.44 | 24,223 | 134,109 |
adenylate cyclase activity
|
729.09 | 10.53 | 22,513 | 207,251 |
cAMP biosynthetic process
|
607.13 | 7.32 | 8,073 | 89,247 |
NAD+ nucleotidase, cyclic ADP-ribose generating
|
3,897.65 | 6.48 | 1,975 | 3,401 |
Totals | 233833 | 12411210 |
No co-occurrence statistics for GO:0016849 based on MANUAL annotations
The top 52 of 52 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorus-oxygen lyase activity
|
26,912.48 | 100.00 | 48 | 48 |
positive regulation of B cell proliferation
|
4,320.40 | 16.05 | 48 | 299 |
NAD+ nucleotidase, cyclic ADP-ribose generating
|
10,764.99 | 7.41 | 4 | 10 |
regulation of neutrophil chemotaxis
|
2,242.71 | 2.86 | 2 | 24 |
uropod
|
1,380.13 | 2.35 | 2 | 39 |
regulation of cellular extravasation
|
13,456.24 | 2.04 | 1 | 2 |
regulation of cell-matrix adhesion
|
1,015.57 | 2.02 | 2 | 53 |
regulation of superoxide metabolic process
|
8,970.83 | 2.00 | 1 | 3 |
hydrolase activity, acting on glycosyl bonds
|
841.01 | 1.82 | 2 | 64 |
regulation of calcium-mediated signaling
|
640.77 | 1.54 | 2 | 84 |
Totals | 216 | 344497 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:4.6 |
2021-01-04 | Added | XREF | EC:4.6.-.- |
2008-11-22 | Added | DEFINITION | Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. |
2008-04-01 | Updated | RELATION | is a GO:0016829 (lyase activity) |
2006-02-09 | Deleted | XREF | EC:4.6.-.- |
2006-02-09 | Added | XREF | EC:4.6 |
2004-04-28 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-16 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2003-09-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | phosphorus-oxygen lyase activity |
2002-02-06 | Updated | TERM | phosphorus-oxygen lyase |
2001-04-03 | Updated | TERM | phosphorus-oxygen lyase |
2001-03-30 | Added | TERM | phosphorus-oxygen lyase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-11-22 | Added | DEFINITION | Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. |
2004-04-28 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-16 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2003-09-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016829 (lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:4.6 |
2021-01-04 | Added | XREF | EC:4.6.-.- |
2006-02-09 | Deleted | XREF | EC:4.6.-.- |
2006-02-09 | Added | XREF | EC:4.6 |
2001-03-30 | Added | XREF | EC:4.6.-.- |
Timestamp | Action | Category | Detail |
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