GO:0016849
JSON
phosphorus-oxygen lyase activity
Molecular Function
Definition (GO:0016849 GONUTS page)
Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Ancestor Chart
Ancestor chart for GO:0016849
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016849
Child Term | Relationship to GO:0016849 |
---|---|
ribonuclease T2 activity
|
is_a |
cytidylate cyclase activity
|
is_a |
glycosylphosphatidylinositol diacylglycerol-lyase activity
|
is_a |
adenylate cyclase activity
|
is_a |
guanylate cyclase activity
|
is_a |
phosphatidylinositol diacylglycerol-lyase activity
|
is_a |
FAD-AMP lyase (cyclizing) activity
|
is_a |
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
|
is_a |
cyclic pyranopterin monophosphate synthase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.6.-.- | |
InterPro | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016849 based on ALL annotations
The top 100 of 549 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorus-oxygen lyase activity
|
7,311.99 | 100.00 | 27,100 | 27,100 |
receptor guanylyl cyclase signaling pathway
|
3,259.45 | 28.17 | 11,746 | 26,350 |
guanylate cyclase activity
|
2,856.87 | 27.86 | 13,349 | 34,166 |
peptide receptor activity
|
3,495.93 | 27.18 | 10,473 | 21,905 |
cGMP biosynthetic process
|
2,630.54 | 26.35 | 13,447 | 37,378 |
cyclase activity
|
3,671.48 | 19.42 | 6,518 | 12,981 |
cyclic nucleotide biosynthetic process
|
1,177.45 | 15.51 | 21,909 | 136,055 |
adenylate cyclase activity
|
791.41 | 10.61 | 22,935 | 211,902 |
NAD+ nucleotidase, cyclic ADP-ribose generating
|
4,321.01 | 7.14 | 2,037 | 3,447 |
cAMP biosynthetic process
|
560.68 | 6.26 | 6,893 | 89,893 |
Totals | 226756 | 12591158 |
No co-occurrence statistics for GO:0016849 based on MANUAL annotations
The top 52 of 52 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorus-oxygen lyase activity
|
25,664.24 | 100.00 | 55 | 55 |
positive regulation of B cell proliferation
|
4,226.15 | 16.47 | 55 | 334 |
NAD+ nucleotidase, cyclic ADP-ribose generating
|
10,265.69 | 6.56 | 4 | 10 |
regulation of neutrophil chemotaxis
|
2,138.69 | 2.60 | 2 | 24 |
uropod
|
1,316.11 | 2.17 | 2 | 39 |
regulation of cell-matrix adhesion
|
933.24 | 1.85 | 2 | 55 |
regulation of cellular extravasation
|
12,832.12 | 1.79 | 1 | 2 |
regulation of superoxide metabolic process
|
8,554.75 | 1.75 | 1 | 3 |
regulation of calcium-mediated signaling
|
633.68 | 1.49 | 2 | 81 |
hydrolase activity, acting on glycosyl bonds
|
534.67 | 1.34 | 2 | 96 |
Totals | 237 | 368153 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:4.6 |
2021-01-04 | Added | XREF | EC:4.6.-.- |
2008-11-22 | Added | DEFINITION | Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. |
2008-04-01 | Updated | RELATION | is a GO:0016829 (lyase activity) |
2006-02-09 | Deleted | XREF | EC:4.6.-.- |
2006-02-09 | Added | XREF | EC:4.6 |
2004-04-28 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-16 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2003-09-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | phosphorus-oxygen lyase activity |
2002-02-06 | Updated | TERM | phosphorus-oxygen lyase |
2001-04-03 | Updated | TERM | phosphorus-oxygen lyase |
2001-03-30 | Added | TERM | phosphorus-oxygen lyase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-11-22 | Added | DEFINITION | Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. |
2004-04-28 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
2004-04-16 | Deleted | SYNONYM | phosphorous-oxygen lyase activity |
2003-09-19 | Added | SYNONYM | phosphorous-oxygen lyase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016829 (lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:4.6 |
2021-01-04 | Added | XREF | EC:4.6.-.- |
2006-02-09 | Deleted | XREF | EC:4.6.-.- |
2006-02-09 | Added | XREF | EC:4.6 |
2001-03-30 | Added | XREF | EC:4.6.-.- |
Timestamp | Action | Category | Detail |
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