This term is obsolete.

GO:0016849 JSON

phosphorus-oxygen lyase activity

Molecular Function

Definition (GO:0016849 GONUTS page)

Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

400,446 annotations

Ancestor Chart

Ancestor chart for GO:0016849
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016849

Child Term Relationship to
GO:0016849
adenylate cyclase activity
is_a
cyclic pyranopterin monophosphate synthase activity
is_a
cytidylate cyclase activity
is_a
guanylate cyclase activity
is_a
FAD-AMP lyase (cyclizing) activity
is_a
ribonuclease T2 activity
is_a
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
is_a
phosphatidylinositol diacylglycerol-lyase activity
is_a
glycosylphosphatidylinositol diacylglycerol-lyase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.6.-.-
InterPro IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016849 based on ALL annotations
The top 100 of 594 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphorus-oxygen lyase activity
6,711.84 100.00 29,044 29,044
receptor guanylyl cyclase signaling pathway
2,984.77 26.18 11,295 25,399
guanylate cyclase activity
2,609.70 26.07 12,833 33,005
peptide receptor activity
3,204.74 25.07 10,037 21,021
cyclase activity
3,931.32 25.01 8,824 15,065
cGMP biosynthetic process
2,402.06 24.76 12,940 36,157
cyclic nucleotide biosynthetic process
1,212.30 17.44 24,223 134,109
adenylate cyclase activity
729.09 10.53 22,513 207,251
cAMP biosynthetic process
607.13 7.32 8,073 89,247
NAD+ nucleotidase, cyclic ADP-ribose generating
3,897.65 6.48 1,975 3,401
Totals 233833 12411210
No co-occurrence statistics for GO:0016849 based on MANUAL annotations
The top 52 of 52 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphorus-oxygen lyase activity
26,912.48 100.00 48 48
positive regulation of B cell proliferation
4,320.40 16.05 48 299
NAD+ nucleotidase, cyclic ADP-ribose generating
10,764.99 7.41 4 10
regulation of neutrophil chemotaxis
2,242.71 2.86 2 24
uropod
1,380.13 2.35 2 39
regulation of cellular extravasation
13,456.24 2.04 1 2
regulation of cell-matrix adhesion
1,015.57 2.02 2 53
regulation of superoxide metabolic process
8,970.83 2.00 1 3
hydrolase activity, acting on glycosyl bonds
841.01 1.82 2 64
regulation of calcium-mediated signaling
640.77 1.54 2 84
Totals 216 344497

Change Log

Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:4.6
2021-01-04 Added XREF EC:4.6.-.-
2008-11-22 Added DEFINITION Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
2008-04-01 Updated RELATION is a GO:0016829 (lyase activity)
2006-02-09 Deleted XREF EC:4.6.-.-
2006-02-09 Added XREF EC:4.6
2004-04-28 Deleted SYNONYM phosphorous-oxygen lyase activity
2004-04-19 Added SYNONYM phosphorous-oxygen lyase activity
2004-04-16 Deleted SYNONYM phosphorous-oxygen lyase activity
2003-09-19 Added SYNONYM phosphorous-oxygen lyase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM phosphorus-oxygen lyase activity
2002-02-06 Updated TERM phosphorus-oxygen lyase
2001-04-03 Updated TERM phosphorus-oxygen lyase
2001-03-30 Added TERM phosphorus-oxygen lyase
Timestamp Action Category Detail
2008-11-22 Added DEFINITION Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
2004-04-28 Deleted SYNONYM phosphorous-oxygen lyase activity
2004-04-19 Added SYNONYM phosphorous-oxygen lyase activity
2004-04-16 Deleted SYNONYM phosphorous-oxygen lyase activity
2003-09-19 Added SYNONYM phosphorous-oxygen lyase activity
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016829 (lyase activity)
Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:4.6
2021-01-04 Added XREF EC:4.6.-.-
2006-02-09 Deleted XREF EC:4.6.-.-
2006-02-09 Added XREF EC:4.6
2001-03-30 Added XREF EC:4.6.-.-
Timestamp Action Category Detail
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