GO:0018833
JSON
DDT-dehydrochlorinase activity
Molecular Function
Definition (GO:0018833 GONUTS page)
Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| DDT-as | related |
| DDT-ase activity | related |
| 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming] | related |
| DDT dehydrochlorinase activity | exact |
| DDTase activity | related |
| 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity | related |
Ancestor Chart
Ancestor chart for GO:0018833
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Annotating to catalytic activities using the IPI evidence code | Link |
| Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
| NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
| Database | ID | Description |
|---|---|---|
| EC | 4.5.1.1 | |
| KEGG_REACTION | R04522 | |
| MetaCyc | DDT-DEHYDROCHLORINASE-RXN | |
| RHEA | 19217 | |
| UM-BBD_reactionID | r0439 |
Cross-Ontology Relations
| Relation | Other Ontology | ID | Term |
|---|---|---|---|
| has_participant | CHEBI | CHEBI:17996 | chloride |
| has_participant | CHEBI | CHEBI:15378 | hydron |
| has_participant | CHEBI | CHEBI:16598 | DDE |
| has_participant | CHEBI | CHEBI:16130 | DDT |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0018833 based on ALL annotations
The top 11 of 11 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
DDT-dehydrochlorinase activity
|
11,656,169.00 | 100.00 | 17 | 17 |
|
glutathione peroxidase activity
|
4,250.59 | 0.04 | 12 | 32,907 |
|
glutathione transferase activity
|
1,156.01 | 0.01 | 16 | 161,329 |
|
glutathione metabolic process
|
652.68 | 0.01 | 15 | 267,884 |
|
protein binding
|
278.64 | 0.00 | 1 | 41,833 |
|
cellular oxidant detoxification
|
165.70 | 0.00 | 12 | 844,124 |
|
response to toxic substance
|
163.47 | 0.00 | 1 | 71,305 |
|
catalytic activity
|
37.56 | 0.00 | 15 | 4,655,290 |
|
lyase activity
|
23.19 | 0.00 | 9 | 4,523,172 |
|
transferase activity
|
14.75 | 0.00 | 9 | 7,114,403 |
| Totals | 108 | 43215921 | ||
No co-occurrence statistics for GO:0018833 based on MANUAL annotations
The top 6 of 6 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
DDT-dehydrochlorinase activity
|
705,766.50 | 100.00 | 2 | 2 |
|
glutathione peroxidase activity
|
1,428.68 | 0.20 | 1 | 494 |
|
glutathione metabolic process
|
178.95 | 0.03 | 1 | 3,944 |
|
glutathione transferase activity
|
166.97 | 0.02 | 1 | 4,227 |
|
protein binding
|
16.87 | 0.00 | 1 | 41,833 |
|
cytoplasm
|
3.57 | 0.00 | 1 | 197,513 |
| Totals | 7 | 248013 | ||
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+). |
| 2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H+. |
| 2020-10-08 | Deleted | SYNONYM | DDTase activity |
| 2020-10-08 | Deleted | SYNONYM | DDT-ase activity |
| 2020-10-08 | Deleted | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity |
| 2020-10-08 | Added | SYNONYM | DDT-ase activity |
| 2020-10-08 | Added | SYNONYM | DDTase activity |
| 2020-10-08 | Added | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity |
| 2019-06-20 | Deleted | XREF | KEGG:R04522 |
| 2019-06-20 | Added | XREF | KEGG_REACTION:R04522 |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2004-01-07 | Updated | TERM | DDT-dehydrochlorinase activity |
| 2003-03-19 | Updated | TERM | DDT dehydrochlorinase activity |
| 2001-10-01 | Added | TERM | DDT dehydrochlorinase |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+). |
| 2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H+. |
| 2020-10-08 | Deleted | SYNONYM | DDTase activity |
| 2020-10-08 | Deleted | SYNONYM | DDT-ase activity |
| 2020-10-08 | Deleted | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity |
| 2020-10-08 | Added | SYNONYM | DDT-ase activity |
| 2020-10-08 | Added | SYNONYM | DDTase activity |
| 2020-10-08 | Added | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity |
| 2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride. |
| 2010-10-11 | Added | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+). |
| 2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride. |
| 2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride. |
| 2007-11-08 | Added | SYNONYM | DDT-ase activity |
| 2007-11-08 | Added | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming] |
| 2007-11-08 | Added | SYNONYM | DDTase activity |
| 2007-11-08 | Added | SYNONYM | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity |
| 2007-11-08 | Added | SYNONYM | DDT-as |
| 2007-08-09 | Added | SYNONYM | DDT dehydrochlorinase activity |
| 2007-08-09 | Deleted | SYNONYM | DDT dehydrochlorinase activity |
| 2006-02-04 | Updated | DEFINITION | Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride. |
| 2004-09-24 | Updated | DEFINITION | Catalysis of the reaction: 1,1,1,-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1,-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride. |
| 2004-04-19 | Added | SYNONYM | DDT dehydrochlorinase activity |
| 2004-04-16 | Deleted | SYNONYM | DDT dehydrochlorinase activity |
| 2004-01-07 | Added | SYNONYM | DDT dehydrochlorinase activity |
| 2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 1,1,1,-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1,-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | is a GO:0016848 (carbon-halide lyase activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2019-06-20 | Deleted | XREF | KEGG:R04522 |
| 2019-06-20 | Added | XREF | KEGG_REACTION:R04522 |
| 2018-07-13 | Added | XREF | RHEA:19217 |
| 2018-07-13 | Deleted | XREF | RHEA:19220 |
| 2011-05-03 | Deleted | XREF | UM-BBD_enzymeID:e0311 |
| 2011-05-03 | Added | XREF | UM-BBD_reactionID:r0439 |
| 2010-10-11 | Added | XREF | RHEA:19220 |
| 2010-10-11 | Added | XREF | KEGG:R04522 |
| 2003-10-27 | Added | XREF | MetaCyc:DDT-DEHYDROCHLORINASE-RXN |
| 2003-10-27 | Added | XREF | UM-BBD_enzymeID:e0311 |
| 2001-10-01 | Added | XREF | EC:4.5.1.1 |
| Timestamp | Action | Category | Detail |
|---|
Please Wait...
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link