GO:0019087
JSON
symbiont-mediated transformation of host cell
Biological Process
Definition (GO:0019087 GONUTS page)
A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses. PMID:11119620 PMID:18366075 PMID:24373315
Secondary IDs
GO:0019088, GO:0020021
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
virus-mediated transformation of host cell | related |
viral transformation | exact |
immortalization of host cell | exact |
transformation of host cell | exact |
immortalization of host cell by virus | related |
host cell transformation | exact |
host cell immortalization | exact |
viral immortalization | exact |
transformation of host cell by virus | exact |
viral transformation of host cell | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0019087
Child Term | Relationship to GO:0019087 |
---|---|
positive regulation of transformation of host cell by virus
|
positively_regulates |
regulation of transformation of host cell by virus
|
regulates |
negative regulation of transformation of host cell by virus
|
negatively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0019087 | symbiont-mediated transformation of host cell | Never in Taxon | 33090 | Viridiplantae | |
GO:0019087 | symbiont-mediated transformation of host cell | Never in Taxon | 4895 | Schizosaccharomyces | |
GO:0019087 | symbiont-mediated transformation of host cell | Never in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004109 | Hepatitis C virus, NS3 protease |
InterPro | IPR007961 | Herpesvirus latent membrane 1 |
Wikipedia | Viral_transformation |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0044864 | obsolete positive regulation by virus of host cell division | replaced_by GO:0019087 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0019087 based on ALL annotations
The top 100 of 137 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated transformation of host cell
|
5,223.40 | 100.00 | 37,936 | 37,936 |
symbiont-mediated suppression of host innate immune response
|
923.68 | 15.40 | 20,652 | 116,787 |
host cell endoplasmic reticulum membrane
|
871.33 | 15.31 | 24,670 | 147,891 |
symbiont-mediated suppression of host TRAF-mediated signal transduction
|
4,576.04 | 14.33 | 5,549 | 6,334 |
host cell endoplasmic reticulum
|
691.92 | 12.37 | 24,668 | 186,223 |
ribonucleoside triphosphate phosphatase activity
|
554.17 | 10.02 | 24,406 | 230,041 |
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
|
2,972.31 | 9.40 | 3,841 | 6,750 |
symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint
|
2,500.72 | 9.12 | 3,842 | 8,025 |
host cell lipid droplet
|
642.60 | 9.12 | 9,885 | 80,350 |
host cell mitochondrion
|
488.40 | 7.38 | 9,831 | 105,142 |
Totals | 764699 | 156840486 |
No co-occurrence statistics for GO:0019087 based on MANUAL annotations
The top 4 of 4 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated transformation of host cell
|
352,883.25 | 100.00 | 4 | 4 |
symbiont-mediated perturbation of host cell cycle progression
|
44,110.41 | 9.09 | 1 | 8 |
zinc ion binding
|
53.21 | 0.02 | 1 | 6,632 |
protein binding
|
25.31 | 0.01 | 3 | 41,833 |
Totals | 9 | 48477 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-16 | Updated | TERM | symbiont-mediated transformation of host cell |
2024-11-16 | Deleted | DEFINITION | A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. |
2024-11-16 | Added | DEFINITION | A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses. |
2024-11-16 | Added | SYNONYM | virus-mediated transformation of host cell |
2024-11-13 | Added | SYNONYM | transformation of host cell by virus |
2024-11-13 | Added | RELATION | is a GO:0044068 (symbiont-mediated perturbation of host cellular process) |
2024-11-13 | Deleted | RELATION | is a GO:0019054 (obsolete modulation by virus of host cellular process) |
2024-11-13 | Updated | TERM | virus-mediated transformation of host cell |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:7742 (Vertebrata) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-16 | Updated | TERM | symbiont-mediated transformation of host cell |
2024-11-13 | Updated | TERM | virus-mediated transformation of host cell |
2005-12-10 | Updated | TERM | transformation of host cell by virus |
2001-10-01 | Added | TERM | viral transformation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-16 | Deleted | DEFINITION | A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. |
2024-11-16 | Added | DEFINITION | A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses. |
2024-11-16 | Added | SYNONYM | virus-mediated transformation of host cell |
2024-11-13 | Added | SYNONYM | transformation of host cell by virus |
2020-02-07 | Added | SYNONYM | host cell transformation |
2020-02-07 | Added | SYNONYM | host cell immortalization |
2020-02-07 | Added | SYNONYM | viral immortalization |
2020-02-07 | Added | SYNONYM | transformation of host cell |
2020-02-07 | Added | SYNONYM | immortalization of host cell |
2020-02-07 | Added | DEFINITION | A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. |
2020-02-07 | Added | SYNONYM | immortalization of host cell by virus |
2020-02-07 | Deleted | DEFINITION | Any virus-induced change in the morphological, biochemical, or growth parameters of a cell. |
2008-05-13 | Added | DEFINITION | Any virus-induced change in the morphological, biochemical, or growth parameters of a cell. |
2008-05-12 | Deleted | DEFINITION | Any virus-induced change in the morphological, biochemical, or growth parameters of a cell. |
2007-08-09 | Deleted | SYNONYM | viral transformation |
2007-08-09 | Deleted | SYNONYM | viral transformation of host cell |
2007-08-09 | Added | SYNONYM | viral transformation of host cell |
2007-08-09 | Added | SYNONYM | viral transformation |
2005-12-10 | Added | SYNONYM | viral transformation |
2005-12-10 | Added | SYNONYM | viral transformation of host cell |
2002-11-27 | Added | DEFINITION | Any virus-induced change in the morphological, biochemical, or growth parameters of a cell. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-13 | Added | RELATION | is a GO:0044068 (symbiont-mediated perturbation of host cellular process) |
2024-11-13 | Deleted | RELATION | is a GO:0019054 (obsolete modulation by virus of host cellular process) |
2022-04-05 | Deleted | RELATION | is a GO:0019048 (obsolete modulation by virus of host process) |
2022-04-05 | Added | RELATION | is a GO:0019054 (obsolete modulation by virus of host cellular process) |
2013-07-12 | Deleted | RELATION | is a GO:0044792 (modulation by virus of host morphology or physiology) |
2013-06-12 | Added | RELATION | is a GO:0044792 (modulation by virus of host morphology or physiology) |
2013-06-12 | Deleted | RELATION | is a GO:0044003 (symbiont-mediated perturbation of host process) |
2008-04-01 | Updated | RELATION | is a GO:0044003 (symbiont-mediated perturbation of host process) |
2008-04-01 | Updated | RELATION | is a GO:0019048 (obsolete modulation by virus of host process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-03-29 | Added | XREF | Wikipedia:Viral_transformation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:7742 (Vertebrata) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33090 (Viridiplantae) |
2020-02-07 | Added | SECONDARY | GO:0019088 (immortalization of host cell by virus) |
2020-02-07 | Added | SECONDARY | GO:0020021 (immortalization of host cell) |
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