This term is obsolete.

GO:0019087 JSON

symbiont-mediated transformation of host cell

Biological Process

Definition (GO:0019087 GONUTS page)

A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses. PMID:11119620 PMID:18366075 PMID:24373315

Secondary IDs

GO:0019088, GO:0020021

37,936 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
virus-mediated transformation of host cell related
viral transformation exact
immortalization of host cell exact
transformation of host cell exact
immortalization of host cell by virus related
host cell transformation exact
host cell immortalization exact
viral immortalization exact
transformation of host cell by virus exact
viral transformation of host cell exact

Ancestor Chart

Ancestor chart for GO:0019087
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019087

Child Term Relationship to
GO:0019087
positive regulation of transformation of host cell by virus
positively_regulates
regulation of transformation of host cell by virus
regulates
negative regulation of transformation of host cell by virus
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0019087 symbiont-mediated transformation of host cell Never in Taxon 33090 Viridiplantae
GO:0019087 symbiont-mediated transformation of host cell Never in Taxon 4895 Schizosaccharomyces
GO:0019087 symbiont-mediated transformation of host cell Never in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
InterPro IPR004109 Hepatitis C virus, NS3 protease
InterPro IPR007961 Herpesvirus latent membrane 1
Wikipedia Viral_transformation

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0044864 obsolete positive regulation by virus of host cell division replaced_by GO:0019087

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0019087 based on ALL annotations
The top 100 of 137 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated transformation of host cell
5,223.40 100.00 37,936 37,936
symbiont-mediated suppression of host innate immune response
923.68 15.40 20,652 116,787
host cell endoplasmic reticulum membrane
871.33 15.31 24,670 147,891
symbiont-mediated suppression of host TRAF-mediated signal transduction
4,576.04 14.33 5,549 6,334
host cell endoplasmic reticulum
691.92 12.37 24,668 186,223
ribonucleoside triphosphate phosphatase activity
554.17 10.02 24,406 230,041
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
2,972.31 9.40 3,841 6,750
symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint
2,500.72 9.12 3,842 8,025
host cell lipid droplet
642.60 9.12 9,885 80,350
host cell mitochondrion
488.40 7.38 9,831 105,142
Totals 764699 156840486
No co-occurrence statistics for GO:0019087 based on MANUAL annotations
The top 4 of 4 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated transformation of host cell
352,883.25 100.00 4 4
symbiont-mediated perturbation of host cell cycle progression
44,110.41 9.09 1 8
zinc ion binding
53.21 0.02 1 6,632
protein binding
25.31 0.01 3 41,833
Totals 9 48477

Change Log

Timestamp Action Category Detail
2024-11-16 Updated TERM symbiont-mediated transformation of host cell
2024-11-16 Deleted DEFINITION A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.
2024-11-16 Added DEFINITION A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses.
2024-11-16 Added SYNONYM virus-mediated transformation of host cell
2024-11-13 Added SYNONYM transformation of host cell by virus
2024-11-13 Added RELATION is a GO:0044068 (symbiont-mediated perturbation of host cellular process)
2024-11-13 Deleted RELATION is a GO:0019054 (obsolete modulation by virus of host cellular process)
2024-11-13 Updated TERM virus-mediated transformation of host cell
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:7742 (Vertebrata)
Timestamp Action Category Detail
2024-11-16 Updated TERM symbiont-mediated transformation of host cell
2024-11-13 Updated TERM virus-mediated transformation of host cell
2005-12-10 Updated TERM transformation of host cell by virus
2001-10-01 Added TERM viral transformation
Timestamp Action Category Detail
2024-11-16 Deleted DEFINITION A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.
2024-11-16 Added DEFINITION A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses.
2024-11-16 Added SYNONYM virus-mediated transformation of host cell
2024-11-13 Added SYNONYM transformation of host cell by virus
2020-02-07 Added SYNONYM host cell transformation
2020-02-07 Added SYNONYM host cell immortalization
2020-02-07 Added SYNONYM viral immortalization
2020-02-07 Added SYNONYM transformation of host cell
2020-02-07 Added SYNONYM immortalization of host cell
2020-02-07 Added DEFINITION A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.
2020-02-07 Added SYNONYM immortalization of host cell by virus
2020-02-07 Deleted DEFINITION Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
2008-05-13 Added DEFINITION Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
2008-05-12 Deleted DEFINITION Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
2007-08-09 Deleted SYNONYM viral transformation
2007-08-09 Deleted SYNONYM viral transformation of host cell
2007-08-09 Added SYNONYM viral transformation of host cell
2007-08-09 Added SYNONYM viral transformation
2005-12-10 Added SYNONYM viral transformation
2005-12-10 Added SYNONYM viral transformation of host cell
2002-11-27 Added DEFINITION Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
Timestamp Action Category Detail
2024-11-13 Added RELATION is a GO:0044068 (symbiont-mediated perturbation of host cellular process)
2024-11-13 Deleted RELATION is a GO:0019054 (obsolete modulation by virus of host cellular process)
2022-04-05 Deleted RELATION is a GO:0019048 (obsolete modulation by virus of host process)
2022-04-05 Added RELATION is a GO:0019054 (obsolete modulation by virus of host cellular process)
2013-07-12 Deleted RELATION is a GO:0044792 (modulation by virus of host morphology or physiology)
2013-06-12 Added RELATION is a GO:0044792 (modulation by virus of host morphology or physiology)
2013-06-12 Deleted RELATION is a GO:0044003 (symbiont-mediated perturbation of host process)
2008-04-01 Updated RELATION is a GO:0044003 (symbiont-mediated perturbation of host process)
2008-04-01 Updated RELATION is a GO:0019048 (obsolete modulation by virus of host process)
Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Viral_transformation
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:7742 (Vertebrata)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2020-02-07 Added SECONDARY GO:0019088 (immortalization of host cell by virus)
2020-02-07 Added SECONDARY GO:0020021 (immortalization of host cell)
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