This term is obsolete.

GO:0019136 JSON

deoxynucleoside kinase activity

Molecular Function

Definition (GO:0019136 GONUTS page)

Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.

52,985 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ATP:deoxynucleoside 5'-phosphotransferase activity related
ms-dNK related
Dm-dNK related
D. melanogaster deoxynucleoside kinase activity related
multispecific deoxynucleoside kinase activity related
multisubstrate deoxyribonucleoside kinase activity related
multifunctional deoxynucleoside kinase activity related
Ms-dNK activity related

Ancestor Chart

Ancestor chart for GO:0019136
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019136

Child Term Relationship to
GO:0019136
deoxyguanosine kinase activity
is_a
deoxycytidine kinase activity
is_a
deoxyadenosine kinase activity
is_a
thymidine kinase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZK09 10116 D3ZK09_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.1.145
InterPro IPR002624 Deoxynucleoside kinase
MetaCyc 2.7.1.145-RXN
RHEA 12140
Reactome R-HSA-74207

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:65317 2'-deoxynucleoside 5'-monophosphate(2-)
has_participant CHEBI CHEBI:456216 ADP(3-)
has_participant CHEBI CHEBI:18274 2'-deoxyribonucleoside
has_participant CHEBI CHEBI:15378 hydron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0019136 based on ALL annotations
The top 100 of 113 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxynucleoside kinase activity
9,472.48 100.00 20,919 20,919
deoxyribonucleoside monophosphate biosynthetic process
3,956.10 41.63 20,753 49,691
deoxyguanosine kinase activity
5,758.29 5.19 1,124 1,849
nucleobase-containing compound metabolic process
476.61 4.99 17,674 351,264
deoxycytidine kinase activity
6,611.82 3.94 839 1,202
deoxyadenosine kinase activity
7,486.32 2.10 441 558
dAMP biosynthetic process
9,322.13 1.78 372 378
dAMP salvage
5,656.23 0.79 166 278
TMP biosynthetic process
884.00 0.53 116 1,243
purine deoxyribonucleoside metabolic process
9,377.76 0.47 99 100
Totals 124671 193554355
No co-occurrence statistics for GO:0019136 based on MANUAL annotations
The top 31 of 31 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxynucleoside kinase activity
8,554.75 100.00 165 165
deoxyguanosine kinase activity
2,774.51 6.32 12 37
dGTP metabolic process
7,699.27 5.42 9 10
purine deoxyribonucleoside metabolic process
7,604.22 4.82 8 9
dAMP salvage
5,264.46 4.71 8 13
deoxycytidine kinase activity
1,996.11 3.72 7 30
mitochondrial ATP synthesis coupled electron transport
506.95 2.74 8 135
deoxyadenosine kinase activity
3,110.82 2.33 4 11
deoxycytidine metabolic process
6,416.06 1.81 3 4
deoxyribonucleotide metabolic process
3,666.32 1.78 3 7
Totals 506 613842

Change Log

Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-74207
2020-10-08 Deleted SYNONYM ATP:deoxynucleoside 5'-phosphotransferase activity
2020-10-08 Added SYNONYM D. melanogaster deoxynucleoside kinase activity
2020-10-08 Added SYNONYM ATP:deoxynucleoside 5'-phosphotransferase activity
2020-10-08 Deleted SYNONYM D. melanogaster deoxynucleoside kinase activity
2020-06-22 Added XREF RHEA:12140
2011-03-11 Added RELATION part of GO:0009157 (deoxyribonucleoside monophosphate biosynthetic process)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
2008-04-01 Updated RELATION is a GO:0019206 (nucleoside kinase activity)
Timestamp Action Category Detail
2003-03-19 Updated TERM deoxynucleoside kinase activity
2001-10-01 Added TERM deoxynucleoside kinase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM ATP:deoxynucleoside 5'-phosphotransferase activity
2020-10-08 Added SYNONYM D. melanogaster deoxynucleoside kinase activity
2020-10-08 Added SYNONYM ATP:deoxynucleoside 5'-phosphotransferase activity
2020-10-08 Deleted SYNONYM D. melanogaster deoxynucleoside kinase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
2007-11-08 Added SYNONYM ms-dNK
2007-11-08 Added SYNONYM D. melanogaster deoxynucleoside kinase activity
2007-11-08 Added SYNONYM ATP:deoxynucleoside 5'-phosphotransferase activity
2007-11-08 Added SYNONYM Dm-dNK
2007-09-06 Added SYNONYM multisubstrate deoxyribonucleoside kinase activity
2007-09-06 Added SYNONYM multispecific deoxynucleoside kinase activity
2007-09-06 Added SYNONYM multifunctional deoxynucleoside kinase activity
2007-09-06 Added SYNONYM Ms-dNK activity
2003-03-26 Updated DEFINITION Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
2002-11-27 Added DEFINITION Catalysis of the phosphorylation of any of the four common deoxynucleosides to the corresponding 2'-deoxynucleoside 5'-phosphates.
Timestamp Action Category Detail
2011-03-11 Added RELATION part of GO:0009157 (deoxyribonucleoside monophosphate biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019206 (nucleoside kinase activity)
Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-74207
2020-06-22 Added XREF RHEA:12140
2003-10-27 Added XREF MetaCyc:2.7.1.145-RXN
2001-10-01 Added XREF EC:2.7.1.145
Timestamp Action Category Detail
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