This term is obsolete.

GO:0019786 JSON

protein-phosphatidylethanolamide deconjugating activity

Molecular Function

Definition (GO:0019786 GONUTS page)

Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue. PMID:22240591 PMID:22652539 PMID:28330855 PMID:2882172 PMID:28901328

10,459 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ATG8-PE deconjugation activity narrow
Atg8-specific protease activity exact
APG8-specific protease activity narrow
ATG8-PE hydrolase activity narrow
Atg8-specific peptidase activity narrow
APG8-PE hydrolase related

Ancestor Chart

Ancestor chart for GO:0019786
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9NHA8 7227 BGBP3_DROME GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089

Cross-references

Database ID Description
InterPro IPR046792 Peptidase C54, catalytic domain

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0019786 based on ALL annotations
The top 100 of 262 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein-phosphatidylethanolamide deconjugating activity
19,406.02 100.00 10,211 10,211
aggrephagy
12,004.04 59.85 9,685 15,657
mitophagy
4,691.99 23.87 9,699 40,115
piecemeal microautophagy of the nucleus
2,866.14 14.65 9,685 65,575
autophagosome assembly
1,686.01 8.65 9,704 111,693
autophagy
1,131.83 5.83 10,106 173,275
cysteine-type endopeptidase activity
996.38 5.12 9,700 188,922
protein processing
772.01 3.97 9,688 243,527
autophagosome
426.76 1.91 1,303 59,251
cysteine-type peptidase activity
347.90 1.79 10,209 569,466
Totals 131108 72967694
No co-occurrence statistics for GO:0019786 based on MANUAL annotations
The top 43 of 43 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein-phosphatidylethanolamide deconjugating activity
6,084.19 100.00 232 232
aggrephagy
3,117.30 50.78 228 445
piecemeal microautophagy of the nucleus
989.44 16.22 228 1,402
mitophagy
668.85 10.97 228 2,074
protein processing
661.20 10.85 228 2,098
cysteine-type peptidase activity
827.24 7.23 31 228
autophagosome assembly
373.61 6.13 228 3,713
cysteine-type endopeptidase activity
309.92 5.09 228 4,476
protein delipidation
3,476.68 4.98 12 21
autophagy
266.01 3.59 39 892
Totals 2032 776058

Change Log

Timestamp Action Category Detail
2023-06-13 Deleted SYNONYM APG8-specific protease activity
2023-06-13 Added SYNONYM Atg8-specific peptidase activity
2023-06-13 Deleted RELATION is a GO:0008234 (cysteine-type peptidase activity)
2023-06-13 Added SYNONYM ATG8-PE hydrolase activity
2023-06-13 Added SYNONYM ATG8-PE deconjugation activity
2023-06-13 Added SYNONYM APG8-specific protease activity
2023-06-13 Deleted RELATION is a GO:0019783 (ubiquitin-like protein peptidase activity)
2023-06-13 Added RELATION is a GO:0016787 (hydrolase activity)
2023-06-13 Added DEFINITION Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.
2023-06-13 Deleted DEFINITION A thiol-dependent isopeptidase activity that cleaves APG8 from a target protein to which it is conjugated.
Timestamp Action Category Detail
2023-06-13 Updated TERM protein-phosphatidylethanolamide deconjugating activity
2022-01-28 Updated TERM Atg8-specific peptidase activity
2014-06-08 Updated TERM Atg8-specific protease activity
2003-03-19 Updated TERM APG8-specific protease activity
2002-01-08 Updated TERM APG8-specific protease
2001-11-13 Added TERM APG8 specific protease
Timestamp Action Category Detail
2023-06-13 Deleted SYNONYM APG8-specific protease activity
2023-06-13 Added SYNONYM Atg8-specific peptidase activity
2023-06-13 Added SYNONYM ATG8-PE hydrolase activity
2023-06-13 Added SYNONYM ATG8-PE deconjugation activity
2023-06-13 Added SYNONYM APG8-specific protease activity
2023-06-13 Added DEFINITION Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.
2023-06-13 Deleted DEFINITION A thiol-dependent isopeptidase activity that cleaves APG8 from a target protein to which it is conjugated.
2022-01-28 Added DEFINITION A thiol-dependent isopeptidase activity that cleaves APG8 from a target protein to which it is conjugated.
2022-01-28 Added SYNONYM Atg8-specific protease activity
2022-01-28 Deleted DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2014-06-08 Added SYNONYM APG8-specific protease activity
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2007-08-09 Deleted SYNONYM APG8-PE hydrolase
2007-08-09 Added SYNONYM APG8-PE hydrolase
2005-07-29 Updated DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2005-07-27 Added DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier, from previously modified substrates.
2004-04-19 Added SYNONYM APG8-PE hydrolase
2004-04-05 Deleted SYNONYM APG8-PE hydrolase
2001-11-13 Added SYNONYM APG8-PE hydrolase
Timestamp Action Category Detail
2023-06-13 Deleted RELATION is a GO:0008234 (cysteine-type peptidase activity)
2023-06-13 Deleted RELATION is a GO:0019783 (ubiquitin-like protein peptidase activity)
2023-06-13 Added RELATION is a GO:0016787 (hydrolase activity)
2023-06-13 Added RELATION is a GO:0140096 (catalytic activity, acting on a protein)
2022-01-28 Added RELATION is a GO:0008234 (cysteine-type peptidase activity)
2016-11-15 Added RELATION has part GO:0000045 (autophagosome assembly)
2008-04-01 Updated RELATION is a GO:0019783 (ubiquitin-like protein peptidase activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
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