GO:0030170
JSON
pyridoxal phosphate binding
Molecular Function
Definition (GO:0030170 GONUTS page)
Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
Ancestor Chart
Ancestor chart for GO:0030170
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000277 | Cys/Met metabolism, pyridoxal phosphate-dependent enzyme |
InterPro | IPR000634 | Serine/threonine dehydratase, pyridoxal-phosphate-binding site |
InterPro | IPR001085 | Serine hydroxymethyltransferase |
InterPro | IPR002129 | Pyridoxal phosphate-dependent decarboxylase |
InterPro | IPR004838 | Aminotransferases, class-I, pyridoxal-phosphate-binding site |
InterPro | IPR004839 | Aminotransferase, class I/classII, large domain |
InterPro | IPR005302 | Molybdenum cofactor sulfurase, C-terminal |
InterPro | IPR005784 | D-amino acid aminotransferase |
InterPro | IPR005814 | Aminotransferase class-III |
InterPro | IPR005957 | Tyrosine aminotransferase |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:597326 | pyridoxal 5'-phosphate(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030170 based on ALL annotations
The top 100 of 3,309 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyridoxal phosphate binding
|
112.80 | 100.00 | 1,728,166 | 1,728,166 |
transaminase activity
|
79.48 | 40.82 | 851,179 | 1,208,015 |
biosynthetic process
|
35.30 | 17.19 | 477,066 | 1,524,289 |
amino acid metabolic process
|
47.85 | 11.23 | 228,984 | 539,854 |
transsulfuration
|
112.45 | 7.73 | 133,565 | 133,984 |
identical protein binding
|
29.52 | 5.68 | 116,864 | 446,538 |
polysaccharide biosynthetic process
|
37.43 | 5.39 | 104,598 | 315,234 |
carboxy-lyase activity
|
19.26 | 4.98 | 113,654 | 665,708 |
glycine hydroxymethyltransferase activity
|
112.08 | 3.89 | 67,171 | 67,605 |
glycine biosynthetic process from serine
|
112.80 | 3.88 | 67,137 | 67,137 |
Totals | 8415981 | 90392216 |
No co-occurrence statistics for GO:0030170 based on MANUAL annotations
The top 100 of 642 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyridoxal phosphate binding
|
583.73 | 100.00 | 2,213 | 2,213 |
glycine hydroxymethyltransferase activity
|
576.99 | 19.30 | 428 | 433 |
glycine biosynthetic process from serine
|
583.73 | 19.16 | 424 | 424 |
tetrahydrofolate metabolic process
|
474.07 | 18.51 | 428 | 527 |
transsulfuration
|
535.73 | 12.47 | 279 | 304 |
glycogen phosphorylase activity
|
570.00 | 11.22 | 249 | 255 |
glycogen catabolic process
|
387.60 | 10.65 | 249 | 375 |
carbon-sulfur lyase activity
|
577.71 | 8.67 | 192 | 194 |
glycine dehydrogenase (decarboxylating) activity
|
551.53 | 6.17 | 137 | 145 |
glycine binding
|
366.47 | 6.10 | 140 | 223 |
Totals | 10086 | 362146 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_metagenomics | 111 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2020-05-08 | Deleted | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.17 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.17 |
2017-11-29 | Added | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2017-02-23 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2017-02-23 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2017-02-23 | Deleted | RELATION | is a GO:0097159 (organic cyclic compound binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | pyridoxal phosphate binding |
2003-03-19 | Updated | TERM | pyridoxal phosphate binding activity |
2001-08-28 | Added | TERM | pyridoxal phosphate binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-02-01 | Deleted | SYNONYM | vitamin B6 binding |
2008-05-13 | Added | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2007-08-09 | Deleted | SYNONYM | vitamin B6 binding |
2007-08-09 | Added | SYNONYM | vitamin B6 binding |
2004-10-08 | Updated | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2004-08-06 | Added | SYNONYM | vitamin B6 binding |
2003-03-26 | Updated | DEFINITION | Interacting selectively with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-05-08 | Deleted | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Added | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2017-02-23 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2017-02-23 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2017-02-23 | Deleted | RELATION | is a GO:0097159 (organic cyclic compound binding) |
2016-11-28 | Added | RELATION | is a GO:0097159 (organic cyclic compound binding) |
2016-11-28 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2016-06-22 | Deleted | RELATION | is a GO:0097159 (organic cyclic compound binding) |
2016-06-22 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2014-02-17 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2014-02-17 | Added | RELATION | is a GO:0097159 (organic cyclic compound binding) |
2012-11-15 | Deleted | RELATION | is a GO:0070279 (vitamin B6 binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2009-02-01 | Deleted | RELATION | is a GO:0019842 (vitamin binding) |
2009-02-01 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2008-04-01 | Updated | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2008-04-01 | Updated | RELATION | is a GO:0019842 (vitamin binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.17 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.17 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-07-23 | Added | SUBSET | goslim_metagenomics |
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