This term is obsolete.

GO:0030170 JSON

pyridoxal phosphate binding

Molecular Function

Definition (GO:0030170 GONUTS page)

Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1,729,982 annotations

Ancestor Chart

Ancestor chart for GO:0030170
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Cross-references

Database ID Description
InterPro IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
InterPro IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site
InterPro IPR001085 Serine hydroxymethyltransferase
InterPro IPR002129 Pyridoxal phosphate-dependent decarboxylase
InterPro IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site
InterPro IPR004839 Aminotransferase, class I/classII, large domain
InterPro IPR005302 Molybdenum cofactor sulfurase, C-terminal
InterPro IPR005784 D-amino acid aminotransferase
InterPro IPR005814 Aminotransferase class-III
InterPro IPR005957 Tyrosine aminotransferase

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:597326 pyridoxal 5'-phosphate(2-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030170 based on ALL annotations
The top 100 of 3,309 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pyridoxal phosphate binding
112.80 100.00 1,728,166 1,728,166
transaminase activity
79.48 40.82 851,179 1,208,015
biosynthetic process
35.30 17.19 477,066 1,524,289
amino acid metabolic process
47.85 11.23 228,984 539,854
transsulfuration
112.45 7.73 133,565 133,984
identical protein binding
29.52 5.68 116,864 446,538
polysaccharide biosynthetic process
37.43 5.39 104,598 315,234
carboxy-lyase activity
19.26 4.98 113,654 665,708
glycine hydroxymethyltransferase activity
112.08 3.89 67,171 67,605
glycine biosynthetic process from serine
112.80 3.88 67,137 67,137
Totals 8415981 90392216
No co-occurrence statistics for GO:0030170 based on MANUAL annotations
The top 100 of 642 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pyridoxal phosphate binding
583.73 100.00 2,213 2,213
glycine hydroxymethyltransferase activity
576.99 19.30 428 433
glycine biosynthetic process from serine
583.73 19.16 424 424
tetrahydrofolate metabolic process
474.07 18.51 428 527
transsulfuration
535.73 12.47 279 304
glycogen phosphorylase activity
570.00 11.22 249 255
glycogen catabolic process
387.60 10.65 249 375
carbon-sulfur lyase activity
577.71 8.67 192 194
glycine dehydrogenase (decarboxylating) activity
551.53 6.17 137 145
glycine binding
366.47 6.10 140 223
Totals 10086 362146

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_metagenomics 111

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2020-05-08 Deleted RELATION is a GO:0050662 (obsolete coenzyme binding)
2020-02-28 Deleted XREF MIPS_funcat:16.21.17
2019-05-04 Added XREF MIPS_funcat:16.21.17
2017-11-29 Added RELATION is a GO:0050662 (obsolete coenzyme binding)
2017-11-29 Deleted RELATION is a GO:0048037 (obsolete cofactor binding)
2017-02-23 Added RELATION is a GO:0070279 (vitamin B6 binding)
2017-02-23 Deleted RELATION is a GO:1901363 (heterocyclic compound binding)
2017-02-23 Deleted RELATION is a GO:0097159 (organic cyclic compound binding)
Timestamp Action Category Detail
2003-06-10 Updated TERM pyridoxal phosphate binding
2003-03-19 Updated TERM pyridoxal phosphate binding activity
2001-08-28 Added TERM pyridoxal phosphate binding
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2009-07-03 Deleted DEFINITION Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2009-02-01 Deleted SYNONYM vitamin B6 binding
2008-05-13 Added DEFINITION Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2008-05-12 Deleted DEFINITION Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2007-08-09 Deleted SYNONYM vitamin B6 binding
2007-08-09 Added SYNONYM vitamin B6 binding
2004-10-08 Updated DEFINITION Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
2004-08-06 Added SYNONYM vitamin B6 binding
2003-03-26 Updated DEFINITION Interacting selectively with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate.
Timestamp Action Category Detail
2020-05-08 Deleted RELATION is a GO:0050662 (obsolete coenzyme binding)
2017-11-29 Added RELATION is a GO:0050662 (obsolete coenzyme binding)
2017-11-29 Deleted RELATION is a GO:0048037 (obsolete cofactor binding)
2017-02-23 Added RELATION is a GO:0070279 (vitamin B6 binding)
2017-02-23 Deleted RELATION is a GO:1901363 (heterocyclic compound binding)
2017-02-23 Deleted RELATION is a GO:0097159 (organic cyclic compound binding)
2016-11-28 Added RELATION is a GO:0097159 (organic cyclic compound binding)
2016-11-28 Added RELATION is a GO:1901363 (heterocyclic compound binding)
2016-06-22 Deleted RELATION is a GO:0097159 (organic cyclic compound binding)
2016-06-22 Deleted RELATION is a GO:1901363 (heterocyclic compound binding)
2014-02-17 Added RELATION is a GO:1901363 (heterocyclic compound binding)
2014-02-17 Added RELATION is a GO:0097159 (organic cyclic compound binding)
2012-11-15 Deleted RELATION is a GO:0070279 (vitamin B6 binding)
2012-11-02 Added RELATION is a GO:0043168 (anion binding)
2009-02-01 Deleted RELATION is a GO:0019842 (vitamin binding)
2009-02-01 Added RELATION is a GO:0070279 (vitamin B6 binding)
2008-04-01 Updated RELATION is a GO:0048037 (obsolete cofactor binding)
2008-04-01 Updated RELATION is a GO:0019842 (vitamin binding)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:16.21.17
2019-05-04 Added XREF MIPS_funcat:16.21.17
Timestamp Action Category Detail
2016-07-23 Added SUBSET goslim_metagenomics
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