GO:0030170
JSON
pyridoxal phosphate binding
Molecular Function
Definition (GO:0030170 GONUTS page)
Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
Ancestor Chart
Ancestor chart for GO:0030170
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000277 | Cys/Met metabolism, pyridoxal phosphate-dependent enzyme |
InterPro | IPR000634 | Serine/threonine dehydratase, pyridoxal-phosphate-binding site |
InterPro | IPR001085 | Serine hydroxymethyltransferase |
InterPro | IPR002129 | Pyridoxal phosphate-dependent decarboxylase |
InterPro | IPR004838 | Aminotransferases, class-I, pyridoxal-phosphate-binding site |
InterPro | IPR004839 | Aminotransferase, class I/classII, large domain |
InterPro | IPR005302 | Molybdenum cofactor sulfurase, C-terminal |
InterPro | IPR005784 | D-amino acid aminotransferase |
InterPro | IPR005814 | Aminotransferase class-III |
InterPro | IPR005957 | Tyrosine aminotransferase |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:597326 | pyridoxal 5'-phosphate(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030170 based on ALL annotations
The top 100 of 3,338 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyridoxal phosphate binding
|
112.54 | 100.00 | 1,760,728 | 1,760,728 |
transaminase activity
|
81.19 | 41.36 | 866,729 | 1,201,488 |
biosynthetic process
|
35.06 | 17.95 | 523,950 | 1,682,002 |
amino acid metabolic process
|
44.83 | 11.05 | 233,643 | 586,483 |
transsulfuration
|
112.19 | 7.70 | 135,665 | 136,086 |
identical protein binding
|
29.56 | 5.69 | 119,149 | 453,648 |
polysaccharide biosynthetic process
|
33.97 | 5.29 | 106,060 | 351,347 |
carboxy-lyase activity
|
19.38 | 5.04 | 117,169 | 680,500 |
catalytic activity
|
7.32 | 4.95 | 302,656 | 4,655,290 |
glycine hydroxymethyltransferase activity
|
111.83 | 3.90 | 68,688 | 69,126 |
Totals | 8663440 | 87902773 |
No co-occurrence statistics for GO:0030170 based on MANUAL annotations
The top 100 of 641 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pyridoxal phosphate binding
|
594.58 | 100.00 | 2,374 | 2,374 |
glycine hydroxymethyltransferase activity
|
588.19 | 19.34 | 460 | 465 |
glycine biosynthetic process from serine
|
594.58 | 19.21 | 456 | 456 |
tetrahydrofolate metabolic process
|
486.67 | 18.58 | 460 | 562 |
transsulfuration
|
548.27 | 12.34 | 296 | 321 |
glycogen phosphorylase activity
|
581.79 | 11.47 | 273 | 279 |
glycogen catabolic process
|
399.80 | 10.89 | 273 | 406 |
carbon-sulfur lyase activity
|
588.81 | 8.59 | 204 | 206 |
glycine dehydrogenase (decarboxylating) activity
|
565.75 | 6.59 | 157 | 165 |
glycine binding
|
383.60 | 6.50 | 160 | 248 |
Totals | 11045 | 388788 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_metagenomics | 111 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2020-05-08 | Deleted | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.17 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.17 |
2017-11-29 | Added | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2017-02-23 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2017-02-23 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2017-02-23 | Deleted | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | pyridoxal phosphate binding |
2003-03-19 | Updated | TERM | pyridoxal phosphate binding activity |
2001-08-28 | Added | TERM | pyridoxal phosphate binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2009-02-01 | Deleted | SYNONYM | vitamin B6 binding |
2008-05-13 | Added | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2007-08-09 | Added | SYNONYM | vitamin B6 binding |
2007-08-09 | Deleted | SYNONYM | vitamin B6 binding |
2004-10-08 | Updated | DEFINITION | Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
2004-08-06 | Added | SYNONYM | vitamin B6 binding |
2003-03-26 | Updated | DEFINITION | Interacting selectively with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with pyridoxal 5' phosphate: 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-05-08 | Deleted | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Added | RELATION | is a GO:0050662 (obsolete coenzyme binding) |
2017-11-29 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2017-02-23 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2017-02-23 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2017-02-23 | Deleted | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2016-11-28 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2016-11-28 | Added | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2016-06-22 | Deleted | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2016-06-22 | Deleted | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2014-02-17 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2014-02-17 | Added | RELATION | is a GO:0097159 (obsolete organic cyclic compound binding) |
2012-11-15 | Deleted | RELATION | is a GO:0070279 (vitamin B6 binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2009-02-01 | Deleted | RELATION | is a GO:0019842 (vitamin binding) |
2009-02-01 | Added | RELATION | is a GO:0070279 (vitamin B6 binding) |
2008-04-01 | Updated | RELATION | is a GO:0019842 (vitamin binding) |
2008-04-01 | Updated | RELATION | is a GO:0048037 (obsolete cofactor binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.17 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.17 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-07-23 | Added | SUBSET | goslim_metagenomics |
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