This term is obsolete.

GO:0030177 JSON

positive regulation of Wnt signaling pathway

Biological Process

Definition (GO:0030177 GONUTS page)

Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.

Secondary IDs

GO:0045811

40,168 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
upregulation of Wnt receptor signaling pathway exact
up-regulation of Wnt receptor signaling pathway exact
up regulation of Wnt receptor signaling pathway exact
stimulation of Wnt receptor signaling pathway narrow
positive regulation of Wnt receptor signalling pathway exact
activation of Wnt receptor signaling pathway narrow
positive regulation of Wnt-activated signaling pathway exact
positive regulation of Wnt receptor signaling pathway exact
positive regulation of frizzled signalling pathway exact
stimulation of frizzled signaling pathway narrow

Ancestor Chart

Ancestor chart for GO:0030177
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030177

Child Term Relationship to
GO:0030177
positive regulation of canonical Wnt signaling pathway
is_a
positive regulation of non-canonical Wnt signaling pathway
is_a
Wnt receptor recycling
part_of

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0030177 positive regulation of Wnt signaling pathway Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2K7K6 10116 A0A0G2K7K6_RAT GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZNT5 10116 A0A8I5ZNT5_RAT GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AGU3 10116 A0A8I6AGU3_RAT GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6KB18 10116 A6KB18_RAT GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZSK6 10116 D3ZSK6_RAT GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q4V6B6 7227 Q4V6B6_DROME GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22508513
NOT-qualified manual protein Q7TN08 10090 DACT2_MOUSE GO:0030111 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17197390

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0035593 obsolete positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region consider GO:0030177
GO:0072381 obsolete positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation consider GO:0030177
GO:1905426 obsolete positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation consider GO:0030177
GO:2000055 obsolete positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification consider GO:0030177

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030177 based on ALL annotations
The top 100 of 1,638 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of Wnt signaling pathway
15,730.32 100.00 12,597 12,597
heparan sulfate proteoglycan metabolic process
15,180.07 28.39 3,614 3,745
glomerular basement membrane development
11,870.35 25.58 3,515 4,658
positive regulation of vascular endothelial growth factor production
9,870.71 24.15 3,551 5,659
protein K29-linked deubiquitination
14,083.22 21.05 2,719 3,037
protein K33-linked deubiquitination
14,078.59 21.05 2,719 3,038
negative regulation of fibroblast growth factor receptor signaling pathway
6,345.51 20.14 3,614 8,959
N-acetylglucosamine-6-sulfatase activity
5,930.46 19.46 3,614 9,586
glycosaminoglycan binding
4,950.31 17.66 3,614 11,484
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
6,911.20 17.09 2,753 6,266
Totals 101500 1827154
No co-occurrence statistics for GO:0030177 based on MANUAL annotations
The top 100 of 1,477 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of Wnt signaling pathway
3,835.69 100.00 368 368
heparan sulfate proteoglycan metabolic process
2,999.70 15.84 61 78
N-acetylglucosamine-6-sulfatase activity
1,695.49 13.71 61 138
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
1,787.82 12.76 55 118
negative regulation of fibroblast growth factor receptor signaling pathway
947.28 11.01 61 247
positive regulation of vascular endothelial growth factor production
1,295.84 10.73 50 148
glomerular basement membrane development
1,343.89 10.50 48 137
glycosaminoglycan binding
688.80 8.49 51 284
K63-linked polyubiquitin modification-dependent protein binding
534.08 7.77 55 395
limb bud formation
1,917.84 7.54 30 60
Totals 2958 13334

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2013-12-11 Updated TERM positive regulation of Wnt signaling pathway
2013-12-11 Added SYNONYM positive regulation of Wnt-activated signaling pathway
2013-12-11 Added SYNONYM positive regulation of Wnt receptor signaling pathway
2013-12-11 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity.
2013-12-11 Added DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2011-01-16 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
Timestamp Action Category Detail
2013-12-11 Updated TERM positive regulation of Wnt signaling pathway
2002-07-16 Updated TERM positive regulation of Wnt receptor signaling pathway
2001-08-30 Added TERM activation of Wnt receptor signaling pathway
Timestamp Action Category Detail
2013-12-11 Added SYNONYM positive regulation of Wnt-activated signaling pathway
2013-12-11 Added SYNONYM positive regulation of Wnt receptor signaling pathway
2013-12-11 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity.
2013-12-11 Added DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
2008-05-13 Added DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity.
2008-05-12 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity.
2007-11-08 Added SYNONYM upregulation of frizzled signaling pathway
2007-11-08 Added SYNONYM activation of frizzled signaling pathway
2007-11-08 Added SYNONYM positive regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM up-regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM up regulation of frizzled signaling pathway
2007-11-08 Added SYNONYM stimulation of frizzled signaling pathway
2007-11-08 Added SYNONYM positive regulation of frizzled signalling pathway
2007-08-09 Added SYNONYM positive regulation of Wnt receptor signalling pathway
2007-08-09 Deleted SYNONYM positive regulation of Wnt receptor signalling pathway
2007-08-09 Added SYNONYM upregulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM up regulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM stimulation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM up-regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM upregulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM up-regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM up regulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM stimulation of Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM activation of Wnt receptor signaling pathway
2007-08-09 Added SYNONYM activation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM up-regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM up regulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM stimulation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM activation of Wnt receptor signaling pathway
2007-02-23 Added SYNONYM upregulation of Wnt receptor signaling pathway
2006-05-04 Updated DEFINITION Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity.
2005-10-21 Updated DEFINITION Any process that activates or increases the rate, frequency or extent of Wnt receptor signaling pathway activity.
2004-04-19 Added SYNONYM positive regulation of Wnt receptor signalling pathway
2004-04-16 Deleted SYNONYM positive regulation of Wnt receptor signalling pathway
2003-11-13 Added SYNONYM positive regulation of Wnt receptor signalling pathway
2002-11-27 Added DEFINITION Any process that activates or increases the rate of Wnt receptor signaling pathway activity.
Timestamp Action Category Detail
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2011-01-16 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2008-04-01 Updated RELATION is a GO:0030111 (regulation of Wnt signaling pathway)
2008-04-01 Updated RELATION is a GO:0009967 (positive regulation of signal transduction)
2008-04-01 Added RELATION positively regulates GO:0016055 (Wnt signaling pathway)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2007-11-08 Added SECONDARY GO:0045811 (positive regulation of frizzled signaling pathway)
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