GO:0031515
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tRNA (m1A) methyltransferase complex
Cellular Component
Definition (GO:0031515 GONUTS page)
A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. PMID:10779558 PMID:14739239
Ancestor Chart
Ancestor chart for GO:0031515
Taxon Constraints
The use of this term should conform to the following taxon constraints:
| Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
|---|---|---|---|---|---|
| GO:0031515 | tRNA (m1A) methyltransferase complex | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR014816 | tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 |
| InterPro | IPR017423 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031515 based on ALL annotations
The top 100 of 300 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
tRNA (m1A) methyltransferase complex
|
9,331.96 | 100.00 | 21,234 | 21,234 |
|
tRNA (adenine(58)-N1)-methyltransferase activity
|
9,320.85 | 78.90 | 16,770 | 16,790 |
|
tRNA methylation
|
606.74 | 6.50 | 21,233 | 326,575 |
|
tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
|
8,598.74 | 1.21 | 258 | 280 |
|
tRNA processing
|
104.05 | 1.11 | 19,824 | 1,777,988 |
|
mRNA (adenine-N1-)-methyltransferase activity
|
9,280.12 | 0.84 | 179 | 180 |
|
methylation
|
43.01 | 0.46 | 16,787 | 3,642,626 |
|
methyltransferase activity
|
41.34 | 0.44 | 16,795 | 3,790,987 |
|
mitochondrial tRNA processing
|
3,452.83 | 0.35 | 74 | 200 |
|
rRNA (adenine) methyltransferase activity
|
163.87 | 0.29 | 74 | 4,214 |
| Totals | 128786 | 40819414 | ||
No co-occurrence statistics for GO:0031515 based on MANUAL annotations
The top 22 of 22 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
tRNA (m1A) methyltransferase complex
|
5,208.61 | 100.00 | 271 | 271 |
|
tRNA methylation
|
415.28 | 7.51 | 153 | 1,919 |
|
tRNA (adenine(58)-N1)-methyltransferase activity
|
3,906.46 | 2.20 | 6 | 8 |
|
mRNA (adenine-N1-)-methyltransferase activity
|
3,472.41 | 1.47 | 4 | 6 |
|
mRNA processing
|
26.19 | 0.43 | 8 | 1,591 |
|
catalytic activity, acting on RNA
|
5,208.61 | 0.37 | 1 | 1 |
|
mitochondrial tRNA processing
|
434.05 | 0.35 | 1 | 12 |
|
rRNA (adenine) methyltransferase activity
|
137.07 | 0.32 | 1 | 38 |
|
tRNA processing
|
12.96 | 0.19 | 2 | 804 |
|
nucleus
|
5.85 | 0.11 | 234 | 208,176 |
| Totals | 724 | 732213 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
| 2024-05-25 | Added | RELATION | capable of GO:0016426 (tRNA (adenine) methyltransferase activity) |
| 2008-08-24 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
| 2008-08-24 | Deleted | RELATION | is a GO:0043234 (protein complex) |
| 2008-08-24 | Deleted | RELATION | part of GO:0043527 (tRNA methyltransferase complex) |
| 2008-08-24 | Added | RELATION | is a GO:0043527 (tRNA methyltransferase complex) |
| 2008-05-13 | Added | DEFINITION | A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
| 2008-05-12 | Deleted | DEFINITION | A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
| 2008-04-01 | Updated | RELATION | part of GO:0043527 (tRNA methyltransferase complex) |
| 2008-04-01 | Updated | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2005-07-23 | Added | TERM | tRNA (m1A) methyltransferase complex |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
| 2008-05-12 | Deleted | DEFINITION | A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
| 2005-11-04 | Updated | DEFINITION | A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. |
| 2005-08-03 | Updated | DEFINITION | A methyltransferase complex involved in the transfer of 1-methyladenosine (m1A) to the tRNA. In yeast, this complex consists of two subunits, namely Gcd10p and Gcd14p. |
| 2005-07-28 | Updated | DEFINITION | A methyltransferase complex involved in the transfer of 1-methyladenosine (m1A) to the tRNA. In yeast, this complex consists of two subunits, namely Gcd10p and Gcd14p |
| 2005-07-23 | Added | DEFINITION | A methyltransferase complex involved in the transfer of 1-methyladenosine (m1A) to the tRNA. In yeast, this complex consists of two subunits namely Gcd10p and Gcd14p |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-05-25 | Added | RELATION | capable of GO:0016426 (tRNA (adenine) methyltransferase activity) |
| 2008-08-24 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
| 2008-08-24 | Deleted | RELATION | is a GO:0043234 (protein complex) |
| 2008-08-24 | Deleted | RELATION | part of GO:0043527 (tRNA methyltransferase complex) |
| 2008-08-24 | Added | RELATION | is a GO:0043527 (tRNA methyltransferase complex) |
| 2008-04-01 | Updated | RELATION | part of GO:0043527 (tRNA methyltransferase complex) |
| 2008-04-01 | Updated | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
| 2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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