GO:0032211
JSON
negative regulation of telomere maintenance via telomerase
Biological Process
Definition (GO:0032211 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| down regulation of telomere maintenance via telomerase activity | exact |
| inhibition of telomere maintenance via telomerase | narrow |
| downregulation of telomere maintenance via telomerase activity | exact |
| down-regulation of telomere maintenance via telomerase activity | exact |
Ancestor Chart
Ancestor chart for GO:0032211
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | F1LM81 | 10116 | TM1L1_RAT | GO:2000278 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | O75674 | 9606 | TM1L1_HUMAN | GO:2000278 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16479011 | |
| NOT-qualified manual | protein | P04085 | 9606 | PDGFA_HUMAN | GO:2000278 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:11788434, PMID:19019919 | |
| NOT-qualified manual | protein | P20033 | 10090 | PDGFA_MOUSE | GO:2000278 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | P28576 | 10116 | PDGFA_RAT | GO:2000278 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
| NOT-qualified manual | protein | P34007 | 9986 | PDGFA_RABIT | GO:2000278 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | Q2KJ15 | 9913 | PDGFA_BOVIN | GO:2000278 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0032211 based on ALL annotations
The top 100 of 601 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of telomere maintenance via telomerase
|
50,691.96 | 100.00 | 3,909 | 3,909 |
|
telomerase inhibitor activity
|
13,705.94 | 21.43 | 1,987 | 7,349 |
|
protein localization to chromosome, telomeric region
|
21,077.85 | 20.98 | 1,163 | 2,797 |
|
CST complex
|
14,352.66 | 19.60 | 1,521 | 5,372 |
|
shelterin complex
|
10,087.28 | 14.04 | 1,263 | 6,347 |
|
telomere capping
|
7,591.25 | 11.70 | 1,362 | 9,095 |
|
telomeric DNA binding
|
3,282.77 | 6.34 | 2,913 | 44,982 |
|
telomere assembly
|
46,678.84 | 5.63 | 221 | 240 |
|
telomeric D-loop disassembly
|
10,251.46 | 5.46 | 272 | 1,345 |
|
telomerase holoenzyme complex
|
3,089.36 | 4.99 | 842 | 13,816 |
| Totals | 26834 | 271511 | ||
No co-occurrence statistics for GO:0032211 based on MANUAL annotations
The top 100 of 532 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of telomere maintenance via telomerase
|
8,503.21 | 100.00 | 166 | 166 |
|
CST complex
|
4,327.98 | 34.27 | 85 | 167 |
|
telomerase inhibitor activity
|
3,408.94 | 29.77 | 89 | 222 |
|
shelterin complex
|
2,524.39 | 14.84 | 38 | 128 |
|
telomere capping
|
1,684.97 | 12.65 | 43 | 217 |
|
protein localization to chromosome, telomeric region
|
1,938.23 | 11.44 | 31 | 136 |
|
telomeric DNA binding
|
823.10 | 9.40 | 127 | 1,312 |
|
telomeric D-loop disassembly
|
2,713.79 | 7.58 | 15 | 47 |
|
G-rich strand telomeric DNA binding
|
1,230.73 | 7.43 | 22 | 152 |
|
nuclear telomere cap complex
|
1,069.27 | 6.73 | 21 | 167 |
| Totals | 1185 | 12483 | ||
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2016-06-22 | Deleted | RELATION | is a GO:0008156 (negative regulation of DNA replication) |
| 2016-04-16 | Added | RELATION | is a GO:2000279 (negative regulation of DNA biosynthetic process) |
| 2015-06-14 | Added | RELATION | is a GO:1904357 (negative regulation of telomere maintenance via telomere lengthening) |
| 2015-06-14 | Deleted | RELATION | is a GO:0032205 (negative regulation of telomere maintenance) |
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0007004 (telomere maintenance via telomerase) |
| 2008-04-01 | Updated | RELATION | is a GO:0008156 (negative regulation of DNA replication) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2006-08-28 | Added | TERM | negative regulation of telomere maintenance via telomerase |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| 2007-11-08 | Deleted | SYNONYM | down-regulation of telomere maintenance via telomerase |
| 2007-11-08 | Deleted | SYNONYM | downregulation of telomere maintenance via telomerase |
| 2007-11-08 | Added | SYNONYM | down regulation of telomere maintenance via telomerase activity |
| 2007-11-08 | Added | SYNONYM | down-regulation of telomere maintenance via telomerase activity |
| 2007-11-08 | Deleted | SYNONYM | down regulation of telomere maintenance via telomerase |
| 2007-11-08 | Added | SYNONYM | downregulation of telomere maintenance via telomerase activity |
| 2007-08-09 | Deleted | SYNONYM | down regulation of telomere maintenance via telomerase |
| 2007-08-09 | Deleted | SYNONYM | inhibition of telomere maintenance via telomerase |
| 2007-08-09 | Deleted | SYNONYM | downregulation of telomere maintenance via telomerase |
| 2007-08-09 | Added | SYNONYM | down regulation of telomere maintenance via telomerase |
| 2007-08-09 | Added | SYNONYM | downregulation of telomere maintenance via telomerase |
| 2007-08-09 | Deleted | SYNONYM | down-regulation of telomere maintenance via telomerase |
| 2007-08-09 | Added | SYNONYM | down-regulation of telomere maintenance via telomerase |
| 2007-08-09 | Added | SYNONYM | inhibition of telomere maintenance via telomerase |
| 2007-02-23 | Added | SYNONYM | down-regulation of telomere maintenance via telomerase |
| 2007-02-23 | Added | SYNONYM | down regulation of telomere maintenance via telomerase |
| 2007-02-23 | Added | SYNONYM | downregulation of telomere maintenance via telomerase |
| 2007-02-23 | Added | SYNONYM | inhibition of telomere maintenance via telomerase |
| 2006-08-29 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2016-06-22 | Deleted | RELATION | is a GO:0008156 (negative regulation of DNA replication) |
| 2016-04-16 | Added | RELATION | is a GO:2000279 (negative regulation of DNA biosynthetic process) |
| 2015-06-14 | Added | RELATION | is a GO:1904357 (negative regulation of telomere maintenance via telomere lengthening) |
| 2015-06-14 | Deleted | RELATION | is a GO:0032205 (negative regulation of telomere maintenance) |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0007004 (telomere maintenance via telomerase) |
| 2008-04-01 | Updated | RELATION | is a GO:0008156 (negative regulation of DNA replication) |
| 2008-04-01 | Updated | RELATION | is a GO:0032205 (negative regulation of telomere maintenance) |
| 2008-04-01 | Updated | RELATION | is a GO:0032210 (regulation of telomere maintenance via telomerase) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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