This term is obsolete.

GO:0042470 JSON

melanosome

Cellular Component

Definition (GO:0042470 GONUTS page)

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. PMID:11584301

38,576 annotations

Ancestor Chart

Ancestor chart for GO:0042470
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042470

Child Term Relationship to
GO:0042470
GO:0033162
melanosome membrane
part_of
GO:0034493
melanosome lumen
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0042470 melanosome Only in Taxon 89593 Craniata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0031410 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR029242 Protein melan-A
InterPro IPR031638 Melanoregulin
UniProtKB-SubCell SL-0161 Melanosome
Wikipedia Melanosome

Cross-Ontology Relations

Relation Other Ontology ID Term
part_of CL CL:0000148 melanocyte

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042470 based on ALL annotations
The top 100 of 2,014 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0042470
melanosome
8,578.20 100.00 23,209 23,209
GO:0032438
melanosome organization
2,768.56 8.22 2,306 7,145
GO:0030665
clathrin-coated vesicle membrane
1,337.27 7.50 2,932 18,808
GO:0033162
melanosome membrane
1,491.44 7.34 2,617 15,052
GO:0030318
melanocyte differentiation
1,974.96 6.95 2,102 9,130
GO:0042438
melanin biosynthetic process
1,250.32 6.18 2,249 15,430
GO:0051283
negative regulation of sequestering of calcium ion
7,632.23 6.07 1,420 1,596
GO:0032402
melanosome transport
4,455.88 5.78 1,416 2,726
GO:0004998
transferrin receptor activity
6,553.79 5.43 1,282 1,678
GO:0019960
C-X3-C chemokine binding
3,740.51 5.35 1,333 3,057
Totals 141801 4898645
No co-occurrence statistics for GO:0042470 based on MANUAL annotations
The top 100 of 678 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0042470
melanosome
4,782.41 100.00 295 295
GO:0032438
melanosome organization
1,479.94 20.15 108 349
GO:0030318
melanocyte differentiation
1,177.21 13.03 64 260
GO:0033162
melanosome membrane
1,659.20 9.47 34 98
GO:0032402
melanosome transport
1,388.44 9.40 36 124
GO:0006583
melanin biosynthetic process from tyrosine
2,537.61 8.18 26 49
GO:0043473
pigmentation
649.87 7.18 39 287
GO:0004167
dopachrome isomerase activity
2,630.33 7.03 22 40
GO:0048066
developmental pigmentation
722.68 7.00 34 225
GO:0021847
ventricular zone neuroblast division
2,446.81 6.96 22 43
Totals 1547 26614

Change Log

Timestamp Action Category Detail
2024-09-05 Deleted CONSTRAINT never_in_taxon NCBITaxon:6237 (Caenorhabditis)
2024-09-05 Deleted CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2024-09-05 Deleted CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-03-22 Added CONSTRAINT in_taxon NCBITaxon:89593 (Craniata)
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2017-01-07 Added CONSTRAINT never_in_taxon NCBITaxon:6237 (Caenorhabditis)
2016-11-26 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2016-10-29 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2009-02-25 Added XREF Wikipedia:Melanosome
Timestamp Action Category Detail
2002-08-10 Added TERM melanosome
Timestamp Action Category Detail
2008-10-02 Deleted DEFINITION A tissue-specific, membrane bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
2008-10-02 Added DEFINITION A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
2008-05-13 Added DEFINITION A tissue-specific, membrane bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
2008-05-12 Deleted DEFINITION A tissue-specific, membrane bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
2004-10-28 Updated DEFINITION A tissue-specific, membrane bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
2002-11-27 Added DEFINITION A tissue-specific cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0048770 (pigment granule)
Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Melanosome
Timestamp Action Category Detail
2024-09-05 Deleted CONSTRAINT never_in_taxon NCBITaxon:6237 (Caenorhabditis)
2024-09-05 Deleted CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2024-09-05 Deleted CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-03-22 Added CONSTRAINT in_taxon NCBITaxon:89593 (Craniata)
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2017-01-07 Added CONSTRAINT never_in_taxon NCBITaxon:6237 (Caenorhabditis)
2016-11-26 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2016-10-29 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
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