This term is obsolete.

GO:0043296 JSON

apical junction complex

Cellular Component

Definition (GO:0043296 GONUTS page)

A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. PMID:12525486 PMID:15196556

100,047 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
apical junction exact
apical cell junction complex exact

Ancestor Chart

Ancestor chart for GO:0043296
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043296

Child Term Relationship to
GO:0043296
bicellular tight junction
part_of
septate junction
part_of
subapical complex
part_of
zonula adherens
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0043296 apical junction complex Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043296 based on ALL annotations
The top 100 of 1,088 co-occurring terms
Co-occurring Term PR S% #Together #Compared
apical junction complex
10,436.35 100.00 18,987 18,987
establishment of centrosome localization
8,659.16 32.48 6,607 7,963
establishment of cell polarity
3,392.92 20.21 6,612 20,338
establishment or maintenance of epithelial cell apical/basal polarity
1,698.76 12.50 6,648 40,842
adherens junction
1,193.47 11.18 15,777 137,963
cortical actin cytoskeleton
1,297.46 9.64 5,702 45,865
protein localization
1,055.82 8.56 6,803 67,245
apical plasma membrane
805.13 7.41 12,348 160,059
cell cortex
563.15 4.92 6,796 125,943
cell-cell junction organization
691.63 3.92 1,666 25,139
Totals 154006 4094350
No co-occurrence statistics for GO:0043296 based on MANUAL annotations
The top 100 of 951 co-occurring terms
Co-occurring Term PR S% #Together #Compared
apical junction complex
3,724.36 100.00 379 379
establishment of centrosome localization
2,255.12 15.64 66 109
establishment or maintenance of epithelial cell apical/basal polarity
553.98 9.72 83 558
adherens junction
357.76 9.07 234 2,436
establishment of cell polarity
381.02 7.09 71 694
cortical actin cytoskeleton
274.36 5.91 87 1,181
apical plasma membrane
187.05 4.73 169 3,365
cell-cell junction organization
292.57 4.55 37 471
germline ring canal formation
3,517.45 4.47 17 18
apical junction assembly
1,396.64 4.40 18 48
Totals 2783 54628

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2013-02-02 Added SYNONYM apical junction
2012-10-29 Deleted RELATION part of GO:0016327 (apicolateral plasma membrane)
2012-02-03 Deleted DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2012-02-03 Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-11-27 Added SYNONYM apical cell junction complex
2008-05-13 Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-05-12 Deleted DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-04-01 Updated RELATION part of GO:0016327 (apicolateral plasma membrane)
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
Timestamp Action Category Detail
2005-01-23 Added TERM apical junction complex
Timestamp Action Category Detail
2013-02-02 Added SYNONYM apical junction
2012-02-03 Deleted DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2012-02-03 Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-11-27 Added SYNONYM apical cell junction complex
2008-05-13 Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-05-12 Deleted DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2005-01-23 Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
Timestamp Action Category Detail
2012-10-29 Deleted RELATION part of GO:0016327 (apicolateral plasma membrane)
2008-04-01 Updated RELATION part of GO:0016327 (apicolateral plasma membrane)
2008-04-01 Updated RELATION is a GO:0005911 (cell-cell junction)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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