GO:0043296
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apical junction complex
Cellular Component
Definition (GO:0043296 GONUTS page)
A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. PMID:12525486 PMID:15196556
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
apical junction | exact |
apical cell junction complex | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0043296
Child Term | Relationship to GO:0043296 |
---|---|
bicellular tight junction
|
part_of |
septate junction
|
part_of |
subapical complex
|
part_of |
zonula adherens
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0043296 | apical junction complex | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043296 based on ALL annotations
The top 100 of 1,088 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
apical junction complex
|
10,436.35 | 100.00 | 18,987 | 18,987 |
establishment of centrosome localization
|
8,659.16 | 32.48 | 6,607 | 7,963 |
establishment of cell polarity
|
3,392.92 | 20.21 | 6,612 | 20,338 |
establishment or maintenance of epithelial cell apical/basal polarity
|
1,698.76 | 12.50 | 6,648 | 40,842 |
adherens junction
|
1,193.47 | 11.18 | 15,777 | 137,963 |
cortical actin cytoskeleton
|
1,297.46 | 9.64 | 5,702 | 45,865 |
protein localization
|
1,055.82 | 8.56 | 6,803 | 67,245 |
apical plasma membrane
|
805.13 | 7.41 | 12,348 | 160,059 |
cell cortex
|
563.15 | 4.92 | 6,796 | 125,943 |
cell-cell junction organization
|
691.63 | 3.92 | 1,666 | 25,139 |
Totals | 154006 | 4094350 |
No co-occurrence statistics for GO:0043296 based on MANUAL annotations
The top 100 of 951 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
apical junction complex
|
3,724.36 | 100.00 | 379 | 379 |
establishment of centrosome localization
|
2,255.12 | 15.64 | 66 | 109 |
establishment or maintenance of epithelial cell apical/basal polarity
|
553.98 | 9.72 | 83 | 558 |
adherens junction
|
357.76 | 9.07 | 234 | 2,436 |
establishment of cell polarity
|
381.02 | 7.09 | 71 | 694 |
cortical actin cytoskeleton
|
274.36 | 5.91 | 87 | 1,181 |
apical plasma membrane
|
187.05 | 4.73 | 169 | 3,365 |
cell-cell junction organization
|
292.57 | 4.55 | 37 | 471 |
germline ring canal formation
|
3,517.45 | 4.47 | 17 | 18 |
apical junction assembly
|
1,396.64 | 4.40 | 18 | 48 |
Totals | 2783 | 54628 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2013-02-02 | Added | SYNONYM | apical junction |
2012-10-29 | Deleted | RELATION | part of GO:0016327 (apicolateral plasma membrane) |
2012-02-03 | Deleted | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2012-02-03 | Added | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2008-11-27 | Added | SYNONYM | apical cell junction complex |
2008-05-13 | Added | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2008-05-12 | Deleted | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2008-04-01 | Updated | RELATION | part of GO:0016327 (apicolateral plasma membrane) |
2008-04-01 | Updated | RELATION | is a GO:0005911 (cell-cell junction) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-01-23 | Added | TERM | apical junction complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-02-02 | Added | SYNONYM | apical junction |
2012-02-03 | Deleted | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2012-02-03 | Added | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2008-11-27 | Added | SYNONYM | apical cell junction complex |
2008-05-13 | Added | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2008-05-12 | Deleted | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
2005-01-23 | Added | DEFINITION | A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-10-29 | Deleted | RELATION | part of GO:0016327 (apicolateral plasma membrane) |
2008-04-01 | Updated | RELATION | part of GO:0016327 (apicolateral plasma membrane) |
2008-04-01 | Updated | RELATION | is a GO:0005911 (cell-cell junction) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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