GO:0043495
JSON
protein-membrane adaptor activity
Molecular Function
Definition (GO:0043495 GONUTS page)
The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
anchoring | related |
membrane-membrane adaptor activity | narrow |
protein membrane adaptor | exact |
protein membrane adaptor activity | exact |
protein membrane anchor | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0043495
Child Term | Relationship to GO:0043495 |
---|---|
proteasome-nuclear membrane anchor activity
|
is_a |
protein-mitochondrial outer membrane tethering activity
|
is_a |
mitochondrion-plasma membrane adaptor activity
|
is_a |
telomere-nuclear envelope anchor activity
|
is_a |
autophagosome-membrane adaptor activity
|
is_a |
spindle pole body-nuclear membrane anchor activity
|
is_a |
chromatin-nuclear membrane anchor activity
|
is_a |
peroxisome-mitochondrion membrane tether activity
|
is_a |
endoplasmic reticulum-plasma membrane adaptor activity
|
is_a |
mitochondrion-mitochondrion outer membrane tether activity
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | F1MA98 | 10116 | TPR_RAT | GO:0043495 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | F6ZDS4 | 10090 | TPR_MOUSE | GO:0043495 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | P12270 | 9606 | TPR_HUMAN | GO:0043495 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:12802065 | |
NOT-qualified manual | protein | Q5EE04 | 8355 | TPR_XENLA | GO:0043495 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q61387 | 10090 | CO72L_MOUSE | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:27775717 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR019568 | Rapsyn, myristoylation/linker region, N-terminal |
InterPro | IPR035293 | Vacuole-related protein 17 |
InterPro | IPR045156 | Vacuolar protein 8 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043495 based on ALL annotations
The top 100 of 1,321 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein-membrane adaptor activity
|
5,201.19 | 100.00 | 38,098 | 38,098 |
meiotic nuclear membrane microtubule tethering complex
|
2,974.46 | 18.05 | 7,952 | 13,905 |
phagophore
|
2,633.97 | 13.65 | 5,997 | 11,842 |
glycophagy
|
1,832.18 | 12.22 | 6,005 | 17,047 |
phagophore assembly site membrane
|
897.74 | 10.33 | 7,803 | 45,208 |
nucleus-vacuole junction assembly
|
5,199.80 | 9.85 | 3,751 | 3,752 |
autophagosome assembly
|
572.49 | 8.94 | 12,294 | 111,693 |
reticulophagy
|
874.43 | 8.86 | 6,007 | 35,730 |
phosphatidylinositol-3-phosphate binding
|
679.42 | 7.69 | 5,997 | 45,909 |
GET complex
|
1,765.09 | 7.49 | 3,339 | 9,839 |
Totals | 240092 | 6721813 |
No co-occurrence statistics for GO:0043495 based on MANUAL annotations
The top 100 of 1,021 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein-membrane adaptor activity
|
998.26 | 100.00 | 1,414 | 1,414 |
endoplasmic reticulum-plasma membrane tethering
|
960.25 | 45.63 | 657 | 683 |
endoplasmic reticulum membrane organization
|
871.47 | 43.27 | 653 | 748 |
meiotic nuclear membrane microtubule tethering complex
|
608.69 | 9.93 | 150 | 246 |
phagophore
|
377.05 | 7.55 | 122 | 323 |
glycophagy
|
146.06 | 5.89 | 127 | 868 |
pexophagy
|
127.50 | 5.46 | 123 | 963 |
nuclear envelope
|
73.87 | 5.44 | 241 | 3,257 |
reticulophagy
|
119.60 | 5.41 | 127 | 1,060 |
autophagy of mitochondrion
|
110.82 | 5.10 | 122 | 1,099 |
Totals | 7348 | 242371 |
Change Log
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- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Added | SYNONYM | membrane-membrane adaptor activity |
2020-03-27 | Added | SYNONYM | protein membrane adaptor activity |
2020-03-27 | Added | DEFINITION | The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. |
2020-03-27 | Deleted | DEFINITION | Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location. |
2020-03-27 | Updated | TERM | protein-membrane adaptor activity |
2020-02-07 | Added | SYNONYM | protein membrane adaptor |
2020-02-07 | Updated | TERM | protein membrane adaptor activity |
2019-11-27 | Added | SYNONYM | protein membrane anchor |
2019-11-27 | Updated | TERM | protein membrane adaptor |
2018-12-06 | Deleted | RELATION | is a GO:0005515 (protein binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-27 | Updated | TERM | protein-membrane adaptor activity |
2020-02-07 | Updated | TERM | protein membrane adaptor activity |
2019-11-27 | Updated | TERM | protein membrane adaptor |
2017-08-13 | Updated | TERM | protein membrane anchor |
2005-10-22 | Added | TERM | protein anchor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Added | SYNONYM | membrane-membrane adaptor activity |
2020-03-27 | Added | SYNONYM | protein membrane adaptor activity |
2020-03-27 | Added | DEFINITION | The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. |
2020-03-27 | Deleted | DEFINITION | Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location. |
2020-02-07 | Added | SYNONYM | protein membrane adaptor |
2019-11-27 | Added | SYNONYM | protein membrane anchor |
2017-04-16 | Deleted | DEFINITION | Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2017-04-16 | Added | DEFINITION | Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2008-05-13 | Added | DEFINITION | Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2007-08-09 | Deleted | SYNONYM | anchoring |
2007-08-09 | Added | SYNONYM | anchoring |
2005-10-22 | Added | DEFINITION | Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane. |
2005-10-22 | Added | SYNONYM | anchoring |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-12-06 | Deleted | RELATION | is a GO:0005515 (protein binding) |
2018-12-06 | Added | RELATION | is a GO:0030674 (protein-macromolecule adaptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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