This term is obsolete.

GO:0043495 JSON

protein-membrane adaptor activity

Molecular Function

Definition (GO:0043495 GONUTS page)

The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.

42,401 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
anchoring related
membrane-membrane adaptor activity narrow
protein membrane adaptor exact
protein membrane adaptor activity exact
protein membrane anchor related

Ancestor Chart

Ancestor chart for GO:0043495
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043495

Child Term Relationship to
GO:0043495
proteasome-nuclear membrane anchor activity
is_a
protein-mitochondrial outer membrane tethering activity
is_a
mitochondrion-plasma membrane adaptor activity
is_a
telomere-nuclear envelope anchor activity
is_a
autophagosome-membrane adaptor activity
is_a
spindle pole body-nuclear membrane anchor activity
is_a
chromatin-nuclear membrane anchor activity
is_a
peroxisome-mitochondrion membrane tether activity
is_a
endoplasmic reticulum-plasma membrane adaptor activity
is_a
mitochondrion-mitochondrion outer membrane tether activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein F1MA98 10116 TPR_RAT GO:0043495 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein F6ZDS4 10090 TPR_MOUSE GO:0043495 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein P12270 9606 TPR_HUMAN GO:0043495 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:12802065
NOT-qualified manual protein Q5EE04 8355 TPR_XENLA GO:0043495 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q61387 10090 CO72L_MOUSE GO:0030674 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:27775717

Cross-references

Database ID Description
InterPro IPR019568 Rapsyn, myristoylation/linker region, N-terminal
InterPro IPR035293 Vacuole-related protein 17
InterPro IPR045156 Vacuolar protein 8

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043495 based on ALL annotations
The top 100 of 1,321 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein-membrane adaptor activity
5,201.19 100.00 38,098 38,098
meiotic nuclear membrane microtubule tethering complex
2,974.46 18.05 7,952 13,905
phagophore
2,633.97 13.65 5,997 11,842
glycophagy
1,832.18 12.22 6,005 17,047
phagophore assembly site membrane
897.74 10.33 7,803 45,208
nucleus-vacuole junction assembly
5,199.80 9.85 3,751 3,752
autophagosome assembly
572.49 8.94 12,294 111,693
reticulophagy
874.43 8.86 6,007 35,730
phosphatidylinositol-3-phosphate binding
679.42 7.69 5,997 45,909
GET complex
1,765.09 7.49 3,339 9,839
Totals 240092 6721813
No co-occurrence statistics for GO:0043495 based on MANUAL annotations
The top 100 of 1,021 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protein-membrane adaptor activity
998.26 100.00 1,414 1,414
endoplasmic reticulum-plasma membrane tethering
960.25 45.63 657 683
endoplasmic reticulum membrane organization
871.47 43.27 653 748
meiotic nuclear membrane microtubule tethering complex
608.69 9.93 150 246
phagophore
377.05 7.55 122 323
glycophagy
146.06 5.89 127 868
pexophagy
127.50 5.46 123 963
nuclear envelope
73.87 5.44 241 3,257
reticulophagy
119.60 5.41 127 1,060
autophagy of mitochondrion
110.82 5.10 122 1,099
Totals 7348 242371

Change Log

Timestamp Action Category Detail
2023-02-28 Added SYNONYM membrane-membrane adaptor activity
2020-03-27 Added SYNONYM protein membrane adaptor activity
2020-03-27 Added DEFINITION The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
2020-03-27 Deleted DEFINITION Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
2020-03-27 Updated TERM protein-membrane adaptor activity
2020-02-07 Added SYNONYM protein membrane adaptor
2020-02-07 Updated TERM protein membrane adaptor activity
2019-11-27 Added SYNONYM protein membrane anchor
2019-11-27 Updated TERM protein membrane adaptor
2018-12-06 Deleted RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
2020-03-27 Updated TERM protein-membrane adaptor activity
2020-02-07 Updated TERM protein membrane adaptor activity
2019-11-27 Updated TERM protein membrane adaptor
2017-08-13 Updated TERM protein membrane anchor
2005-10-22 Added TERM protein anchor
Timestamp Action Category Detail
2023-02-28 Added SYNONYM membrane-membrane adaptor activity
2020-03-27 Added SYNONYM protein membrane adaptor activity
2020-03-27 Added DEFINITION The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
2020-03-27 Deleted DEFINITION Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
2020-02-07 Added SYNONYM protein membrane adaptor
2019-11-27 Added SYNONYM protein membrane anchor
2017-04-16 Deleted DEFINITION Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2017-04-16 Added DEFINITION Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2009-07-03 Deleted DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2008-05-13 Added DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2008-05-12 Deleted DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2007-08-09 Deleted SYNONYM anchoring
2007-08-09 Added SYNONYM anchoring
2005-10-22 Added DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2005-10-22 Added SYNONYM anchoring
Timestamp Action Category Detail
2018-12-06 Deleted RELATION is a GO:0005515 (protein binding)
2018-12-06 Added RELATION is a GO:0030674 (protein-macromolecule adaptor activity)
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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