GO:0043517
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positive regulation of DNA damage response, signal transduction by p53 class mediator
Biological Process
Definition (GO:0043517 GONUTS page)
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
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positive regulation of p53 induced by DNA damage response | exact |
upregulation of DNA damage response, signal transduction by p53 class mediator | exact |
up-regulation of DNA damage response, signal transduction by p53 class mediator | exact |
up regulation of DNA damage response, signal transduction by p53 class mediator | exact |
stimulation of DNA damage response, signal transduction by p53 class mediator | narrow |
activation of DNA damage response, signal transduction by p53 class mediator | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0043517
Child Term | Relationship to GO:0043517 |
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positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
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is_a |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR042450 | Eukaryotic translation elongation factor 1 epsilon-1 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043517 based on ALL annotations
The top 100 of 424 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of DNA damage response, signal transduction by p53 class mediator
|
94,953.13 | 100.00 | 2,053 | 2,053 |
replicative senescence
|
21,399.04 | 8.89 | 263 | 1,167 |
positive regulation of telomerase catalytic core complex assembly
|
94,953.13 | 8.28 | 170 | 170 |
establishment of RNA localization to telomere
|
94,953.13 | 8.28 | 170 | 170 |
regulation of protein deacetylation
|
49,667.79 | 4.75 | 102 | 195 |
MH2 domain binding
|
59,121.76 | 4.69 | 99 | 159 |
vasculogenesis involved in coronary vascular morphogenesis
|
45,855.41 | 4.59 | 99 | 205 |
negative regulation of lens fiber cell differentiation
|
26,105.71 | 4.39 | 102 | 371 |
phospholipase C/protein kinase C signal transduction
|
32,096.83 | 4.28 | 96 | 284 |
oxidative stress-induced premature senescence
|
30,768.79 | 4.14 | 93 | 287 |
Totals | 13688 | 559640 |
No co-occurrence statistics for GO:0043517 based on MANUAL annotations
The top 100 of 324 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of DNA damage response, signal transduction by p53 class mediator
|
19,873.83 | 100.00 | 65 | 65 |
miRNA transcription
|
11,233.04 | 17.33 | 13 | 23 |
oxidative stress-induced premature senescence
|
10,334.39 | 16.88 | 13 | 25 |
replicative senescence
|
4,907.12 | 15.87 | 20 | 81 |
positive regulation of arachidonate secretion
|
10,368.96 | 15.79 | 12 | 23 |
regulation of miRNA transcription
|
12,776.03 | 12.86 | 9 | 14 |
regulation of skeletal muscle cell differentiation
|
4,874.71 | 12.38 | 13 | 53 |
regulation of protein deacetylation
|
10,521.44 | 12.33 | 9 | 17 |
MH2 domain binding
|
8,517.36 | 11.69 | 9 | 21 |
positive regulation of telomerase catalytic core complex assembly
|
19,873.83 | 10.77 | 7 | 7 |
Totals | 688 | 12613 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
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2023-01-16 | Deleted | RELATION | is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus) |
2013-01-20 | Deleted | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2013-01-20 | Added | RELATION | is a GO:1901798 (positive regulation of signal transduction by p53 class mediator) |
2011-09-04 | Added | RELATION | is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus) |
2011-01-30 | Deleted | RELATION | is a GO:0048584 (positive regulation of response to stimulus) |
2011-01-16 | Deleted | RELATION | is a GO:0035468 (positive regulation of signaling pathway) |
2010-10-06 | Added | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2010-04-21 | Deleted | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2010-04-21 | Added | RELATION | is a GO:0035468 (positive regulation of signaling pathway) |
2008-05-13 | Added | DEFINITION | Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. |
Timestamp | Action | Category | Detail |
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2005-10-29 | Added | TERM | positive regulation of DNA damage response, signal transduction by p53 class mediator |
Timestamp | Action | Category | Detail |
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2008-05-13 | Added | DEFINITION | Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. |
2008-05-12 | Deleted | DEFINITION | Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. |
2007-08-09 | Deleted | SYNONYM | upregulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Deleted | SYNONYM | stimulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Deleted | SYNONYM | positive regulation of p53 induced by DNA damage response |
2007-08-09 | Deleted | SYNONYM | up regulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Deleted | SYNONYM | up-regulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Added | SYNONYM | activation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Added | SYNONYM | positive regulation of p53 induced by DNA damage response |
2007-08-09 | Added | SYNONYM | stimulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Added | SYNONYM | up regulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Added | SYNONYM | up-regulation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Deleted | SYNONYM | activation of DNA damage response, signal transduction by p53 class mediator |
2007-08-09 | Added | SYNONYM | upregulation of DNA damage response, signal transduction by p53 class mediator |
2007-02-23 | Added | SYNONYM | upregulation of DNA damage response, signal transduction by p53 class mediator |
2007-02-23 | Added | SYNONYM | up-regulation of DNA damage response, signal transduction by p53 class mediator |
2007-02-23 | Added | SYNONYM | up regulation of DNA damage response, signal transduction by p53 class mediator |
2007-02-23 | Added | SYNONYM | stimulation of DNA damage response, signal transduction by p53 class mediator |
2007-02-23 | Added | SYNONYM | activation of DNA damage response, signal transduction by p53 class mediator |
2005-10-29 | Added | DEFINITION | Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. |
2005-10-29 | Added | SYNONYM | positive regulation of p53 induced by DNA damage response |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-01-16 | Deleted | RELATION | is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus) |
2013-01-20 | Deleted | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2013-01-20 | Added | RELATION | is a GO:1901798 (positive regulation of signal transduction by p53 class mediator) |
2011-09-04 | Added | RELATION | is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus) |
2011-01-30 | Deleted | RELATION | is a GO:0048584 (positive regulation of response to stimulus) |
2011-01-16 | Deleted | RELATION | is a GO:0035468 (positive regulation of signaling pathway) |
2010-10-06 | Added | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2010-04-21 | Deleted | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
2010-04-21 | Added | RELATION | is a GO:0035468 (positive regulation of signaling pathway) |
2008-04-01 | Added | RELATION | positively regulates GO:0030330 (DNA damage response, signal transduction by p53 class mediator) |
2008-04-01 | Updated | RELATION | is a GO:0043516 (regulation of DNA damage response, signal transduction by p53 class mediator) |
2008-04-01 | Updated | RELATION | is a GO:0048584 (positive regulation of response to stimulus) |
2008-04-01 | Updated | RELATION | is a GO:0009967 (positive regulation of signal transduction) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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