This term is obsolete.

GO:0043517 JSON

positive regulation of DNA damage response, signal transduction by p53 class mediator

Biological Process

Definition (GO:0043517 GONUTS page)

Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.

2,431 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
positive regulation of p53 induced by DNA damage response exact
upregulation of DNA damage response, signal transduction by p53 class mediator exact
up-regulation of DNA damage response, signal transduction by p53 class mediator exact
up regulation of DNA damage response, signal transduction by p53 class mediator exact
stimulation of DNA damage response, signal transduction by p53 class mediator narrow
activation of DNA damage response, signal transduction by p53 class mediator narrow

Ancestor Chart

Ancestor chart for GO:0043517
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043517

Child Term Relationship to
GO:0043517
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
is_a

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Cross-references

Database ID Description
InterPro IPR042450 Eukaryotic translation elongation factor 1 epsilon-1

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043517 based on ALL annotations
The top 100 of 424 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of DNA damage response, signal transduction by p53 class mediator
94,953.13 100.00 2,053 2,053
replicative senescence
21,399.04 8.89 263 1,167
positive regulation of telomerase catalytic core complex assembly
94,953.13 8.28 170 170
establishment of RNA localization to telomere
94,953.13 8.28 170 170
regulation of protein deacetylation
49,667.79 4.75 102 195
MH2 domain binding
59,121.76 4.69 99 159
vasculogenesis involved in coronary vascular morphogenesis
45,855.41 4.59 99 205
negative regulation of lens fiber cell differentiation
26,105.71 4.39 102 371
phospholipase C/protein kinase C signal transduction
32,096.83 4.28 96 284
oxidative stress-induced premature senescence
30,768.79 4.14 93 287
Totals 13688 559640
No co-occurrence statistics for GO:0043517 based on MANUAL annotations
The top 100 of 324 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of DNA damage response, signal transduction by p53 class mediator
19,873.83 100.00 65 65
miRNA transcription
11,233.04 17.33 13 23
oxidative stress-induced premature senescence
10,334.39 16.88 13 25
replicative senescence
4,907.12 15.87 20 81
positive regulation of arachidonate secretion
10,368.96 15.79 12 23
regulation of miRNA transcription
12,776.03 12.86 9 14
regulation of skeletal muscle cell differentiation
4,874.71 12.38 13 53
regulation of protein deacetylation
10,521.44 12.33 9 17
MH2 domain binding
8,517.36 11.69 9 21
positive regulation of telomerase catalytic core complex assembly
19,873.83 10.77 7 7
Totals 688 12613

Change Log

Timestamp Action Category Detail
2023-01-16 Deleted RELATION is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus)
2013-01-20 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2013-01-20 Added RELATION is a GO:1901798 (positive regulation of signal transduction by p53 class mediator)
2011-09-04 Added RELATION is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus)
2011-01-30 Deleted RELATION is a GO:0048584 (positive regulation of response to stimulus)
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-10-06 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2008-05-13 Added DEFINITION Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Timestamp Action Category Detail
2005-10-29 Added TERM positive regulation of DNA damage response, signal transduction by p53 class mediator
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2008-05-12 Deleted DEFINITION Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2007-08-09 Deleted SYNONYM upregulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Deleted SYNONYM stimulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Deleted SYNONYM positive regulation of p53 induced by DNA damage response
2007-08-09 Deleted SYNONYM up regulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Deleted SYNONYM up-regulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Added SYNONYM activation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Added SYNONYM positive regulation of p53 induced by DNA damage response
2007-08-09 Added SYNONYM stimulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Added SYNONYM up regulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Added SYNONYM up-regulation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Deleted SYNONYM activation of DNA damage response, signal transduction by p53 class mediator
2007-08-09 Added SYNONYM upregulation of DNA damage response, signal transduction by p53 class mediator
2007-02-23 Added SYNONYM upregulation of DNA damage response, signal transduction by p53 class mediator
2007-02-23 Added SYNONYM up-regulation of DNA damage response, signal transduction by p53 class mediator
2007-02-23 Added SYNONYM up regulation of DNA damage response, signal transduction by p53 class mediator
2007-02-23 Added SYNONYM stimulation of DNA damage response, signal transduction by p53 class mediator
2007-02-23 Added SYNONYM activation of DNA damage response, signal transduction by p53 class mediator
2005-10-29 Added DEFINITION Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
2005-10-29 Added SYNONYM positive regulation of p53 induced by DNA damage response
Timestamp Action Category Detail
2023-01-16 Deleted RELATION is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus)
2013-01-20 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2013-01-20 Added RELATION is a GO:1901798 (positive regulation of signal transduction by p53 class mediator)
2011-09-04 Added RELATION is a GO:2001022 (obsolete positive regulation of response to DNA damage stimulus)
2011-01-30 Deleted RELATION is a GO:0048584 (positive regulation of response to stimulus)
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-10-06 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2008-04-01 Added RELATION positively regulates GO:0030330 (DNA damage response, signal transduction by p53 class mediator)
2008-04-01 Updated RELATION is a GO:0043516 (regulation of DNA damage response, signal transduction by p53 class mediator)
2008-04-01 Updated RELATION is a GO:0048584 (positive regulation of response to stimulus)
2008-04-01 Updated RELATION is a GO:0009967 (positive regulation of signal transduction)
Timestamp Action Category Detail
Timestamp Action Category Detail
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