GO:0045127
JSON
N-acetylglucosamine kinase activity
Molecular Function
Definition (GO:0045127 GONUTS page)
Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
acetylglucosamine kinase (phosphorylating) | related |
2-acetylamino-2-deoxy-D-glucose kinase activity | related |
GlcNAc kinase activity | related |
ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity | related |
ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity | related |
acetylaminodeoxyglucokinase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A1Z6G6 | 7227 | A1Z6G6_DROME | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6IDC6 | 10116 | A6IDC6_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L7 | 10116 | A6K8L7_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L8 | 10116 | A6K8L8_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZHG3 | 10116 | D3ZHG3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZK09 | 10116 | D3ZK09_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.1.59 | |
InterPro | IPR023505 | N-acetyl-D-glucosamine kinase |
InterPro | IPR039758 | N-acetyl-D-glucosamine kinase NAGK-like |
KEGG_REACTION | R01201 | |
MetaCyc | N-ACETYLGLUCOSAMINE-KINASE-RXN | |
RHEA | 17417 | |
Reactome | R-HSA-6803771 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:57513 | N-acetyl-D-glucosamine 6-phosphate(2-) |
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:506227 | N-acetyl-D-glucosamine |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045127 based on ALL annotations
The top 100 of 163 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
N-acetylglucosamine kinase activity
|
28,978.56 | 100.00 | 6,727 | 6,727 |
carbohydrate phosphorylation
|
677.73 | 2.34 | 6,727 | 287,637 |
N-acetylglucosamine metabolic process
|
589.83 | 1.90 | 1,541 | 75,710 |
muramyl dipeptide kinase activity
|
28,978.56 | 1.25 | 84 | 84 |
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
|
6,895.75 | 1.20 | 84 | 353 |
response to fructose
|
787.46 | 1.12 | 125 | 4,600 |
response to muramyl dipeptide
|
2,372.01 | 1.08 | 83 | 1,014 |
peptidoglycan turnover
|
303.67 | 1.01 | 1,585 | 151,254 |
amino sugar catabolic process
|
273.85 | 0.69 | 170 | 17,989 |
carbon-oxygen lyase activity
|
218.81 | 0.58 | 170 | 22,514 |
Totals | 28299 | 67236412 |
No co-occurrence statistics for GO:0045127 based on MANUAL annotations
The top 41 of 41 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
N-acetylglucosamine kinase activity
|
25,329.39 | 100.00 | 51 | 51 |
muramyl dipeptide kinase activity
|
25,329.39 | 9.80 | 5 | 5 |
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
|
4,871.04 | 6.94 | 5 | 26 |
response to muramyl dipeptide
|
1,489.96 | 3.48 | 4 | 68 |
N-acylmannosamine kinase activity
|
1,489.96 | 2.41 | 2 | 34 |
N-acetylmuramic acid metabolic process
|
4,221.57 | 1.79 | 1 | 6 |
N-acetylglucosamine catabolic process
|
569.20 | 1.78 | 4 | 178 |
mannokinase activity
|
734.19 | 1.69 | 2 | 69 |
carbohydrate phosphorylation
|
527.70 | 1.38 | 2 | 96 |
development of symbiont in host
|
1,101.28 | 1.37 | 1 | 23 |
Totals | 135 | 587182 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-22 | Deleted | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+. |
2024-05-22 | Added | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+. |
2020-10-08 | Deleted | SYNONYM | 2-acetylamino-2-deoxy-D-glucose kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | acetylaminodeoxyglucokinase activity |
2020-10-08 | Added | SYNONYM | acetylaminodeoxyglucokinase activity |
2020-10-08 | Added | SYNONYM | ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-06-09 | Updated | TERM | N-acetylglucosamine kinase activity |
2010-06-08 | Updated | TERM | N-acetylglucosamine kinase activity |
2003-03-19 | Updated | TERM | N-acetylglucosamine kinase activity |
2002-04-18 | Added | TERM | N-acetylglucosamine kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-22 | Deleted | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+. |
2024-05-22 | Added | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+. |
2020-10-08 | Deleted | SYNONYM | 2-acetylamino-2-deoxy-D-glucose kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | acetylaminodeoxyglucokinase activity |
2020-10-08 | Added | SYNONYM | acetylaminodeoxyglucokinase activity |
2020-10-08 | Added | SYNONYM | ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | GlcNAc kinase activity |
2020-10-08 | Added | SYNONYM | acetylglucosamine kinase (phosphorylating) |
2020-10-08 | Added | SYNONYM | GlcNAc kinase activity |
2020-10-08 | Deleted | SYNONYM | acetylglucosamine kinase (phosphorylating) |
2020-10-08 | Added | SYNONYM | 2-acetylamino-2-deoxy-D-glucose kinase activity |
2020-10-08 | Added | SYNONYM | ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+). |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. |
2007-11-08 | Added | SYNONYM | acetylglucosamine kinase (phosphorylating) |
2007-11-08 | Added | SYNONYM | acetylaminodeoxyglucokinase activity |
2007-11-08 | Added | SYNONYM | ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity |
2007-11-08 | Added | SYNONYM | 2-acetylamino-2-deoxy-D-glucose kinase activity |
2007-11-08 | Added | SYNONYM | ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity |
2007-09-06 | Added | SYNONYM | GlcNAc kinase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0019200 (carbohydrate kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R01201 |
2019-06-20 | Added | XREF | KEGG_REACTION:R01201 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-6803771 |
2019-04-01 | Added | XREF | Reactome:R-HSA-6803771 |
2018-12-11 | Added | XREF | reactome:R-HSA-6803771 |
2018-07-13 | Deleted | XREF | RHEA:17420 |
2018-07-13 | Added | XREF | RHEA:17417 |
2010-10-11 | Added | XREF | KEGG:R01201 |
2010-10-11 | Added | XREF | RHEA:17420 |
2003-10-27 | Added | XREF | MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN |
2002-04-18 | Added | XREF | EC:2.7.1.59 |
Timestamp | Action | Category | Detail |
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