This term is obsolete.

GO:0045127 JSON

N-acetylglucosamine kinase activity

Molecular Function

Definition (GO:0045127 GONUTS page)

Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+.

6,784 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
acetylglucosamine kinase (phosphorylating) related
2-acetylamino-2-deoxy-D-glucose kinase activity related
GlcNAc kinase activity related
ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity related
ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity related
acetylaminodeoxyglucokinase activity related

Ancestor Chart

Ancestor chart for GO:0045127
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZK09 10116 D3ZK09_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.1.59
InterPro IPR023505 N-acetyl-D-glucosamine kinase
InterPro IPR039758 N-acetyl-D-glucosamine kinase NAGK-like
KEGG_REACTION R01201
MetaCyc N-ACETYLGLUCOSAMINE-KINASE-RXN
RHEA 17417
Reactome R-HSA-6803771

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:57513 N-acetyl-D-glucosamine 6-phosphate(2-)
has_participant CHEBI CHEBI:456216 ADP(3-)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:506227 N-acetyl-D-glucosamine

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045127 based on ALL annotations
The top 100 of 163 co-occurring terms
Co-occurring Term PR S% #Together #Compared
N-acetylglucosamine kinase activity
28,978.56 100.00 6,727 6,727
carbohydrate phosphorylation
677.73 2.34 6,727 287,637
N-acetylglucosamine metabolic process
589.83 1.90 1,541 75,710
muramyl dipeptide kinase activity
28,978.56 1.25 84 84
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
6,895.75 1.20 84 353
response to fructose
787.46 1.12 125 4,600
response to muramyl dipeptide
2,372.01 1.08 83 1,014
peptidoglycan turnover
303.67 1.01 1,585 151,254
amino sugar catabolic process
273.85 0.69 170 17,989
carbon-oxygen lyase activity
218.81 0.58 170 22,514
Totals 28299 67236412
No co-occurrence statistics for GO:0045127 based on MANUAL annotations
The top 41 of 41 co-occurring terms
Co-occurring Term PR S% #Together #Compared
N-acetylglucosamine kinase activity
25,329.39 100.00 51 51
muramyl dipeptide kinase activity
25,329.39 9.80 5 5
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
4,871.04 6.94 5 26
response to muramyl dipeptide
1,489.96 3.48 4 68
N-acylmannosamine kinase activity
1,489.96 2.41 2 34
N-acetylmuramic acid metabolic process
4,221.57 1.79 1 6
N-acetylglucosamine catabolic process
569.20 1.78 4 178
mannokinase activity
734.19 1.69 2 69
carbohydrate phosphorylation
527.70 1.38 2 96
development of symbiont in host
1,101.28 1.37 1 23
Totals 135 587182

Change Log

Timestamp Action Category Detail
2024-05-22 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.
2024-05-22 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.
2020-10-08 Deleted SYNONYM 2-acetylamino-2-deoxy-D-glucose kinase activity
2020-10-08 Deleted SYNONYM ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM acetylaminodeoxyglucokinase activity
2020-10-08 Added SYNONYM acetylaminodeoxyglucokinase activity
2020-10-08 Added SYNONYM ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity
Timestamp Action Category Detail
2010-06-09 Updated TERM N-acetylglucosamine kinase activity
2010-06-08 Updated TERM N-acetylglucosamine kinase activity
2003-03-19 Updated TERM N-acetylglucosamine kinase activity
2002-04-18 Added TERM N-acetylglucosamine kinase
Timestamp Action Category Detail
2024-05-22 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.
2024-05-22 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.
2020-10-08 Deleted SYNONYM 2-acetylamino-2-deoxy-D-glucose kinase activity
2020-10-08 Deleted SYNONYM ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM acetylaminodeoxyglucokinase activity
2020-10-08 Added SYNONYM acetylaminodeoxyglucokinase activity
2020-10-08 Added SYNONYM ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM GlcNAc kinase activity
2020-10-08 Added SYNONYM acetylglucosamine kinase (phosphorylating)
2020-10-08 Added SYNONYM GlcNAc kinase activity
2020-10-08 Deleted SYNONYM acetylglucosamine kinase (phosphorylating)
2020-10-08 Added SYNONYM 2-acetylamino-2-deoxy-D-glucose kinase activity
2020-10-08 Added SYNONYM ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
2007-11-08 Added SYNONYM acetylglucosamine kinase (phosphorylating)
2007-11-08 Added SYNONYM acetylaminodeoxyglucokinase activity
2007-11-08 Added SYNONYM ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity
2007-11-08 Added SYNONYM 2-acetylamino-2-deoxy-D-glucose kinase activity
2007-11-08 Added SYNONYM ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity
2007-09-06 Added SYNONYM GlcNAc kinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0019200 (carbohydrate kinase activity)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R01201
2019-06-20 Added XREF KEGG_REACTION:R01201
2019-04-01 Deleted XREF reactome:R-HSA-6803771
2019-04-01 Added XREF Reactome:R-HSA-6803771
2018-12-11 Added XREF reactome:R-HSA-6803771
2018-07-13 Deleted XREF RHEA:17420
2018-07-13 Added XREF RHEA:17417
2010-10-11 Added XREF KEGG:R01201
2010-10-11 Added XREF RHEA:17420
2003-10-27 Added XREF MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN
2002-04-18 Added XREF EC:2.7.1.59
Timestamp Action Category Detail
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