This term is obsolete.
Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.

GO:0045332 JSON

phospholipid translocation

Biological Process

Definition (GO:0045332 GONUTS page)

The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. PMID:16452632 PMID:20043909 PMID:20302864

Comments

Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.

96,680 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
phospholipid scrambling related
flippase related

Ancestor Chart

Ancestor chart for GO:0045332
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045332

Child Term Relationship to
GO:0045332
negative regulation of phospholipid translocation
negatively_regulates
regulation of phospholipid translocation
regulates
aminophospholipid translocation
is_a
positive regulation of phospholipid translocation
positively_regulates
lysophospholipid translocation
is_a
plasma membrane phospholipid scrambling
is_a

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:16247 phospholipid

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045332 based on ALL annotations
The top 100 of 1,028 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phospholipid translocation
3,234.16 100.00 60,275 60,275
ATPase-coupled intramembrane lipid transporter activity
3,065.87 77.66 48,897 51,581
phospholipid transport
898.61 24.12 38,965 140,237
trans-Golgi network
515.07 13.45 27,973 175,644
phosphatidylethanolamine flippase activity
3,217.33 7.61 4,590 4,614
Golgi organization
277.84 5.41 7,691 89,527
post-Golgi vesicle-mediated transport
981.97 5.33 3,659 12,051
recycling endosome
308.26 5.09 5,936 62,279
phosphatidic acid transfer activity
2,081.00 4.56 2,817 4,378
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
224.95 4.48 6,748 97,019
Totals 504609 80625194
No co-occurrence statistics for GO:0045332 based on MANUAL annotations
The top 100 of 612 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phospholipid translocation
988.37 100.00 1,307 1,307
ATPase-coupled intramembrane lipid transporter activity
971.49 78.19 1,036 1,054
trans-Golgi network
80.97 6.81 377 4,602
phospholipid-translocating ATPase complex
858.04 5.99 79 91
phosphatidic acid transfer activity
271.64 5.44 83 302
Golgi vesicle budding
430.42 3.92 54 124
mitochondrial intermembrane space
59.34 3.20 84 1,399
recycling endosome
51.99 2.93 81 1,540
phosphatidylethanolamine flippase activity
867.84 2.74 36 41
phosphatidylcholine floppase activity
494.18 2.61 35 70
Totals 6015 208503

Change Log

Timestamp Action Category Detail
2018-10-05 Added SYNONYM phospholipid scrambling
2018-10-05 Deleted RELATION has part GO:0017121 (plasma membrane phospholipid scrambling)
2013-07-12 Added RELATION has part GO:0017121 (plasma membrane phospholipid scrambling)
2010-10-31 Added DEFINITION The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
2010-10-31 Deleted DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2010-01-31 Deleted RELATION is a GO:0016044 (cellular membrane organization)
2008-05-13 Added DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2008-05-12 Deleted DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2008-04-01 Updated RELATION is a GO:0034204 (lipid translocation)
2008-04-01 Updated RELATION is a GO:0016044 (cellular membrane organization)
Timestamp Action Category Detail
2002-07-04 Added TERM phospholipid translocation
Timestamp Action Category Detail
2018-10-05 Added SYNONYM phospholipid scrambling
2010-10-31 Added DEFINITION The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
2010-10-31 Deleted DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2008-05-13 Added DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2008-05-12 Deleted DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2008-01-31 Added SYNONYM flippase
2006-10-21 Updated DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2002-11-27 Added DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a plasma membrane to the opposite monolayer.
Timestamp Action Category Detail
2018-10-05 Deleted RELATION has part GO:0017121 (plasma membrane phospholipid scrambling)
2013-07-12 Added RELATION has part GO:0017121 (plasma membrane phospholipid scrambling)
2010-01-31 Deleted RELATION is a GO:0016044 (cellular membrane organization)
2008-04-01 Updated RELATION is a GO:0034204 (lipid translocation)
2008-04-01 Updated RELATION is a GO:0016044 (cellular membrane organization)
2008-04-01 Updated RELATION is a GO:0015914 (phospholipid transport)
Timestamp Action Category Detail
Timestamp Action Category Detail
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