Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.
GO:0045332
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phospholipid translocation
Biological Process
Definition (GO:0045332 GONUTS page)
The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. PMID:16452632 PMID:20043909 PMID:20302864
Comments
Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
phospholipid scrambling | related |
flippase | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045332
Child Term | Relationship to GO:0045332 |
---|---|
negative regulation of phospholipid translocation
|
negatively_regulates |
regulation of phospholipid translocation
|
regulates |
aminophospholipid translocation
|
is_a |
positive regulation of phospholipid translocation
|
positively_regulates |
lysophospholipid translocation
|
is_a |
plasma membrane phospholipid scrambling
|
is_a |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:16247 | phospholipid |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045332 based on ALL annotations
The top 100 of 1,028 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phospholipid translocation
|
3,234.16 | 100.00 | 60,275 | 60,275 |
ATPase-coupled intramembrane lipid transporter activity
|
3,065.87 | 77.66 | 48,897 | 51,581 |
phospholipid transport
|
898.61 | 24.12 | 38,965 | 140,237 |
trans-Golgi network
|
515.07 | 13.45 | 27,973 | 175,644 |
phosphatidylethanolamine flippase activity
|
3,217.33 | 7.61 | 4,590 | 4,614 |
Golgi organization
|
277.84 | 5.41 | 7,691 | 89,527 |
post-Golgi vesicle-mediated transport
|
981.97 | 5.33 | 3,659 | 12,051 |
recycling endosome
|
308.26 | 5.09 | 5,936 | 62,279 |
phosphatidic acid transfer activity
|
2,081.00 | 4.56 | 2,817 | 4,378 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
|
224.95 | 4.48 | 6,748 | 97,019 |
Totals | 504609 | 80625194 |
No co-occurrence statistics for GO:0045332 based on MANUAL annotations
The top 100 of 612 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phospholipid translocation
|
988.37 | 100.00 | 1,307 | 1,307 |
ATPase-coupled intramembrane lipid transporter activity
|
971.49 | 78.19 | 1,036 | 1,054 |
trans-Golgi network
|
80.97 | 6.81 | 377 | 4,602 |
phospholipid-translocating ATPase complex
|
858.04 | 5.99 | 79 | 91 |
phosphatidic acid transfer activity
|
271.64 | 5.44 | 83 | 302 |
Golgi vesicle budding
|
430.42 | 3.92 | 54 | 124 |
mitochondrial intermembrane space
|
59.34 | 3.20 | 84 | 1,399 |
recycling endosome
|
51.99 | 2.93 | 81 | 1,540 |
phosphatidylethanolamine flippase activity
|
867.84 | 2.74 | 36 | 41 |
phosphatidylcholine floppase activity
|
494.18 | 2.61 | 35 | 70 |
Totals | 6015 | 208503 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2018-10-05 | Added | SYNONYM | phospholipid scrambling |
2018-10-05 | Deleted | RELATION | has part GO:0017121 (plasma membrane phospholipid scrambling) |
2013-07-12 | Added | RELATION | has part GO:0017121 (plasma membrane phospholipid scrambling) |
2010-10-31 | Added | DEFINITION | The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. |
2010-10-31 | Deleted | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2010-01-31 | Deleted | RELATION | is a GO:0016044 (cellular membrane organization) |
2008-05-13 | Added | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2008-05-12 | Deleted | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2008-04-01 | Updated | RELATION | is a GO:0034204 (lipid translocation) |
2008-04-01 | Updated | RELATION | is a GO:0016044 (cellular membrane organization) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-07-04 | Added | TERM | phospholipid translocation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-10-05 | Added | SYNONYM | phospholipid scrambling |
2010-10-31 | Added | DEFINITION | The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. |
2010-10-31 | Deleted | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2008-05-13 | Added | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2008-05-12 | Deleted | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2008-01-31 | Added | SYNONYM | flippase |
2006-10-21 | Updated | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. |
2002-11-27 | Added | DEFINITION | The translocation, or flipping, of phospholipid molecules from one monolayer of a plasma membrane to the opposite monolayer. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-10-05 | Deleted | RELATION | has part GO:0017121 (plasma membrane phospholipid scrambling) |
2013-07-12 | Added | RELATION | has part GO:0017121 (plasma membrane phospholipid scrambling) |
2010-01-31 | Deleted | RELATION | is a GO:0016044 (cellular membrane organization) |
2008-04-01 | Updated | RELATION | is a GO:0034204 (lipid translocation) |
2008-04-01 | Updated | RELATION | is a GO:0016044 (cellular membrane organization) |
2008-04-01 | Updated | RELATION | is a GO:0015914 (phospholipid transport) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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